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Items: 1 to 50 of 81

1.

Protein Expression of PTTG1 as a Diagnostic Biomarker in Adrenocortical Carcinoma.

Romero Arenas MA, Whitsett TG, Aronova A, Henderson SA, LoBello J, Habra MA, Grubbs EG, Lee JE, Sircar K, Zarnegar R, Scognamiglio T, Fahey TJ, Perrier ND, Demeure MJ.

Ann Surg Oncol. 2018 Mar;25(3):801-807. doi: 10.1245/s10434-017-6297-1. Epub 2017 Dec 7.

PMID:
29218429
2.

STMN1 is Overexpressed in Adrenocortical Carcinoma and Promotes a More Aggressive Phenotype In Vitro.

Aronova A, Min IM, Crowley MJP, Panjwani SJ, Finnerty BM, Scognamiglio T, Liu YF, Whitsett TG, Garg S, Demeure MJ, Elemento O, Zarnegar R, Fahey TJ III.

Ann Surg Oncol. 2018 Mar;25(3):792-800. doi: 10.1245/s10434-017-6296-2. Epub 2017 Dec 6.

PMID:
29214451
3.

Micrometastatic gastric glomus tumour confirmed by next-generation sequencing.

Davis J, Petterson M, Newell J, Lauwers GY, Royce T, Demeure MJ.

Histopathology. 2018 Jan;72(2):351-354. doi: 10.1111/his.13303. Epub 2017 Oct 24. No abstract available.

PMID:
28675515
4.

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.

Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MCBV, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA; Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW.

Cancer Cell. 2016 Aug 8;30(2):363. doi: 10.1016/j.ccell.2016.07.013. Epub 2016 Aug 8. No abstract available.

5.

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.

Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MCBV, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA; Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW.

Cancer Cell. 2016 May 9;29(5):723-736. doi: 10.1016/j.ccell.2016.04.002. Erratum in: Cancer Cell. 2016 Aug 8;30(2):363.

6.

Pathway Implications of Aberrant Global Methylation in Adrenocortical Cancer.

Legendre CR, Demeure MJ, Whitsett TG, Gooden GC, Bussey KJ, Jung S, Waibhav T, Kim S, Salhia B.

PLoS One. 2016 Mar 10;11(3):e0150629. doi: 10.1371/journal.pone.0150629. eCollection 2016.

7.

Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma.

Bussey KJ, Bapat A, Linnehan C, Wandoloski M, Dastrup E, Rogers E, Gonzales P, Demeure MJ.

Clin Transl Med. 2016 Mar;5(1):1. doi: 10.1186/s40169-015-0080-3. Epub 2016 Jan 11.

8.

Molecular Profiling of Refractory Adrenocortical Cancers and Predictive Biomarkers to Therapy.

Millis SZ, Ejadi S, Demeure MJ.

Biomark Cancer. 2015 Dec 17;7:69-76. doi: 10.4137/BIC.S34292. eCollection 2015.

9.

Correlative Studies in Clinical Trials: A Position Statement From the International Thyroid Oncology Group.

Bible KC, Cote GJ, Demeure MJ, Elisei R, Jhiang S, Ringel MD; International Thyroid Oncology Group Correlative Science Committee.

J Clin Endocrinol Metab. 2015 Dec;100(12):4387-95. doi: 10.1210/jc.2015-2818. Epub 2015 Sep 29.

10.

Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study.

Fassnacht M, Berruti A, Baudin E, Demeure MJ, Gilbert J, Haak H, Kroiss M, Quinn DI, Hesseltine E, Ronchi CL, Terzolo M, Choueiri TK, Poondru S, Fleege T, Rorig R, Chen J, Stephens AW, Worden F, Hammer GD.

Lancet Oncol. 2015 Apr;16(4):426-35. doi: 10.1016/S1470-2045(15)70081-1. Epub 2015 Mar 18.

11.

Solitary liver metastasis from follicular variant papillary thyroid carcinoma: A case report and literature review.

Djenic B, Duick D, Newell JO, Demeure MJ.

Int J Surg Case Rep. 2015;6C:146-9. doi: 10.1016/j.ijscr.2014.11.080. Epub 2014 Dec 12.

12.

ZNF367 inhibits cancer progression and is targeted by miR-195.

Jain M, Zhang L, Boufraqech M, Liu-Chittenden Y, Bussey K, Demeure MJ, Wu X, Su L, Pacak K, Stratakis CA, Kebebew E.

PLoS One. 2014 Jul 21;9(7):e101423. doi: 10.1371/journal.pone.0101423. eCollection 2014.

13.

Whole-genome sequencing of an aggressive BRAF wild-type papillary thyroid cancer identified EML4-ALK translocation as a therapeutic target.

Demeure MJ, Aziz M, Rosenberg R, Gurley SD, Bussey KJ, Carpten JD.

World J Surg. 2014 Jun;38(6):1296-305. doi: 10.1007/s00268-014-2485-3.

PMID:
24633422
14.

Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis.

Porterfield M, Zhao P, Han H, Cunningham J, Aoki K, Von Hoff DD, Demeure MJ, Pierce JM, Tiemeyer M, Wells L.

J Proteome Res. 2014 Feb 7;13(2):395-407. doi: 10.1021/pr400422g. Epub 2013 Dec 12.

15.

PTTG1 overexpression in adrenocortical cancer is associated with poor survival and represents a potential therapeutic target.

Demeure MJ, Coan KE, Grant CS, Komorowski RA, Stephan E, Sinari S, Mount D, Bussey KJ.

Surgery. 2013 Dec;154(6):1405-16; discussion 1416. doi: 10.1016/j.surg.2013.06.058.

16.

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

Weiss GJ, Liang WS, Demeure MJ, Kiefer JA, Hostetter G, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Phillips L, Benson H, Reiman R, Baker A, Marsh V, Von Hoff DD, Carpten JD, Craig DW.

PLoS One. 2013 Oct 30;8(10):e76438. doi: 10.1371/journal.pone.0076438. eCollection 2013.

17.

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs.

Christoforides A, Carpten JD, Weiss GJ, Demeure MJ, Von Hoff DD, Craig DW.

BMC Genomics. 2013 May 4;14:302. doi: 10.1186/1471-2164-14-302.

18.

Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.

Spivak-Kroizman TR, Hostetter G, Posner R, Aziz M, Hu C, Demeure MJ, Von Hoff D, Hingorani SR, Palculict TB, Izzo J, Kiriakova GM, Abdelmelek M, Bartholomeusz G, James BP, Powis G.

Cancer Res. 2013 Jun 1;73(11):3235-47. doi: 10.1158/0008-5472.CAN-11-1433. Epub 2013 Apr 30.

19.

Genomic analysis and selected molecular pathways in rare cancers.

Liu SV, Lenkiewicz E, Evers L, Holley T, Kiefer J, Ruiz C, Glatz K, Bubendorf L, Demeure MJ, Eng C, Ramanathan RK, Von Hoff DD, Barrett MT.

Phys Biol. 2012 Dec;9(6):065004. doi: 10.1088/1478-3975/9/6/065004. Epub 2012 Nov 29.

PMID:
23196986
20.

Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.

Liang WS, Craig DW, Carpten J, Borad MJ, Demeure MJ, Weiss GJ, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Barrett M, Phillips L, Benson H, Tembe W, Braggio E, Kiefer JA, Legendre C, Posner R, Hostetter GH, Baker A, Egan JB, Han H, Lake D, Stites EC, Ramanathan RK, Fonseca R, Stewart AK, Von Hoff D.

PLoS One. 2012;7(10):e43192. doi: 10.1371/journal.pone.0043192. Epub 2012 Oct 10.

21.

A fly in the ointment: reassessing mitotane's role in the treatment of adrenocortical carcinoma.

Bapat AA, Demeure MJ, Bussey KJ.

Pharmacogenomics. 2012 Aug;13(11):1207-9. doi: 10.2217/pgs.12.90. No abstract available.

22.

Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability.

Demeure MJ, Craig DW, Sinari S, Moses TM, Christoforides A, Dinh J, Izatt T, Aldrich J, Decker A, Baker A, Cherni I, Watanabe A, Koep L, Lake D, Hostetter G, Trent JM, Von Hoff DD, Carpten JD.

Genome Med. 2012 Jul 4;4(7):56. doi: 10.1186/gm357. eCollection 2012.

23.

Targeted therapies for adrenocortical carcinoma: IGF and beyond.

Demeure MJ, Bussey KJ, Kirschner LS.

Horm Cancer. 2011 Dec;2(6):385-92. doi: 10.1007/s12672-011-0090-6. Review.

PMID:
22170383
24.

Preclinical investigation of nanoparticle albumin-bound paclitaxel as a potential treatment for adrenocortical cancer.

Demeure MJ, Stephan E, Sinari S, Mount D, Gately S, Gonzales P, Hostetter G, Komorowski R, Kiefer J, Grant CS, Han H, Von Hoff DD, Bussey KJ.

Ann Surg. 2012 Jan;255(1):140-6. doi: 10.1097/SLA.0b013e3182402d21.

PMID:
22156929
25.

Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.

Katchman BA, Antwi K, Hostetter G, Demeure MJ, Watanabe A, Decker GA, Miller LJ, Von Hoff DD, Lake DF.

Mol Cancer Res. 2011 Dec;9(12):1621-31. doi: 10.1158/1541-7786.MCR-11-0018. Epub 2011 Oct 11.

26.

Advancing a clinically relevant perspective of the clonal nature of cancer.

Ruiz C, Lenkiewicz E, Evers L, Holley T, Robeson A, Kiefer J, Demeure MJ, Hollingsworth MA, Shen M, Prunkard D, Rabinovitch PS, Zellweger T, Mousses S, Trent JM, Carpten JD, Bubendorf L, Von Hoff D, Barrett MT.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12054-9. doi: 10.1073/pnas.1104009108. Epub 2011 Jul 5.

27.

Genomic signatures of cancer: basis for individualized risk assessment, selective staging and therapy.

Baehner FL, Lee M, Demeure MJ, Bussey KJ, Kiefer JA, Barrett MT.

J Surg Oncol. 2011 May 1;103(6):563-73. doi: 10.1002/jso.21838. Review.

PMID:
21480251
28.

Toward a pathway-centered approach for the treatment of adrenocortical carcinoma.

Bussey KJ, Demeure MJ.

Curr Opin Oncol. 2011 Jan;23(1):34-44. doi: 10.1097/CCO.0b013e328340d879. Review.

PMID:
21045685
29.

Surgery: Does laparoscopic adrenalectomy have a role in suspected ACC?

Demeure MJ.

Nat Rev Urol. 2010 Oct;7(10):538-9. doi: 10.1038/nrurol.2010.146. No abstract available.

PMID:
20930864
30.

Multi-institutional tumor banking: lessons learned from a pancreatic cancer biospecimen repository.

Demeure MJ, Sielaff T, Koep L, Prinz R, Moser AJ, Zeh H 3rd, Hostetter G, Black J, Decker A, Rosewell S, Bussey KJ, Von Hoff D.

Pancreas. 2010 Oct;39(7):949-54. doi: 10.1097/MPA.0b013e3181df27a8. Review.

PMID:
20861694
31.

Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer.

Schwartz DL, Bankson JA, Lemos R Jr, Lai SY, Thittai AK, He Y, Hostetter G, Demeure MJ, Von Hoff DD, Powis G.

Mol Cancer Ther. 2010 Jul;9(7):2057-67. doi: 10.1158/1535-7163.MCT-09-0768. Epub 2010 Jun 29.

32.

Personalized medicine: the future is not what it used to be.

Demeure MJ.

Surgery. 2009 Dec;146(6):971-8. doi: 10.1016/j.surg.2009.10.023. No abstract available.

33.

Adrenocortical cancer.

Wandoloski M, Bussey KJ, Demeure MJ.

Surg Clin North Am. 2009 Oct;89(5):1255-67. doi: 10.1016/j.suc.2009.06.019. Review.

PMID:
19836496
34.

Analysis of the plasma peptidome from pancreas cancer patients connects a peptide in plasma to overexpression of the parent protein in tumors.

Antwi K, Hostetter G, Demeure MJ, Katchman BA, Decker GA, Ruiz Y, Sielaff TD, Koep LJ, Lake DF.

J Proteome Res. 2009 Oct;8(10):4722-31. doi: 10.1021/pr900414f.

PMID:
19795908
35.

Genomic and expression profiling of adrenocortical carcinoma: application to diagnosis, prognosis and treatment.

Bussey KJ, Demeure MJ.

Future Oncol. 2009 Jun;5(5):641-55. doi: 10.2217/fon.09.45. Review.

PMID:
19519204
36.

Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer.

Balagurunathan Y, Morse DL, Hostetter G, Shanmugam V, Stafford P, Shack S, Pearson J, Trissal M, Demeure MJ, Von Hoff DD, Hruby VJ, Gillies RJ, Han H.

Mol Cancer Ther. 2008 Sep;7(9):3071-80. doi: 10.1158/1535-7163.MCT-08-0402. Epub 2008 Sep 2.

37.

Adrenocortical carcinoma survival rates correlated to genomic copy number variants.

Stephan EA, Chung TH, Grant CS, Kim S, Von Hoff DD, Trent JM, Demeure MJ.

Mol Cancer Ther. 2008 Feb;7(2):425-31. doi: 10.1158/1535-7163.MCT-07-0267.

38.

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells.

Stephens B, Han H, Hostetter G, Demeure MJ, Von Hoff DD.

Mol Cancer Ther. 2008 Jan;7(1):202-10. doi: 10.1158/1535-7163.MCT-07-0542. Epub 2008 Jan 9.

39.

End-of-procedure cefazolin concentrations after administration for prevention of surgical-site infection.

Koopman E, Nix DE, Erstad BL, Demeure MJ, Hayes MM, Ruth JT, Matthias KR.

Am J Health Syst Pharm. 2007 Sep 15;64(18):1927-34.

PMID:
17823104
40.

The elderly surgical patient and postoperative delirium.

Demeure MJ, Fain MJ.

J Am Coll Surg. 2006 Nov;203(5):752-7. Epub 2006 Sep 26. No abstract available. Erratum in: J Am Coll Surg. 2007 Jan;204(1):191.

PMID:
17084339
41.

Islet cell tumors.

Mittendorf EA, Shifrin AL, Inabnet WB, Libutti SK, McHenry CR, Demeure MJ.

Curr Probl Surg. 2006 Oct;43(10):685-765. Review. No abstract available.

PMID:
17055796
42.

Detection of multiple gland primary hyperparathyroidism in the era of minimally invasive parathyroidectomy.

Sugg SL, Krzywda EA, Demeure MJ, Wilson SD.

Surgery. 2004 Dec;136(6):1303-9.

PMID:
15657591
43.

Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice.

Grippo PJ, Nowlin PS, Demeure MJ, Longnecker DS, Sandgren EP.

Cancer Res. 2003 May 1;63(9):2016-9.

44.

Improved survival in resected biliary malignancies.

Nakeeb A, Tran KQ, Black MJ, Erickson BA, Ritch PS, Quebbeman EJ, Wilson SD, Demeure MJ, Rilling WS, Dua KS, Pitt HA.

Surgery. 2002 Oct;132(4):555-63; discission 563-4.

PMID:
12407338
45.

Effect of gender on endothelium-dependent dilation to bradykinin in human adipose microvessels.

Sato A, Miura H, Liu Y, Somberg LB, Otterson MF, Demeure MJ, Schulte WJ, Eberhardt LM, Loberiza FR, Sakuma I, Gutterman DD.

Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H845-52.

46.

Nonfunctioning islet cell carcinoma of the pancreas.

Neeleman S, Demeure MJ.

Curr Treat Options Oncol. 2002 Aug;3(4):355-60. Review.

PMID:
12074772
47.

Patient-based surgical outcome tool demonstrating alleviation of symptoms following parathyroidectomy in patients with primary hyperparathyroidism.

Pasieka JL, Parsons LL, Demeure MJ, Wilson S, Malycha P, Jones J, Krzywda B.

World J Surg. 2002 Aug;26(8):942-9. Epub 2002 May 21.

PMID:
12016473
48.

Cystic pancreatic neuroendocrine tumors: is preoperative diagnosis possible?

Ahrendt SA, Komorowski RA, Demeure MJ, Wilson SD, Pitt HA.

J Gastrointest Surg. 2002 Jan-Feb;6(1):66-74.

PMID:
11986020
49.

Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.

Ahrendt SA, Decker PA, Alawi EA, Zhu Yr YR, Sanchez-Cespedes M, Yang SC, Haasler GB, Kajdacsy-Balla A, Demeure MJ, Sidransky D.

Cancer. 2001 Sep 15;92(6):1525-30.

PMID:
11745231
50.

Subtotal parathyroidectomy in renal failure: still needed after all these years.

Decker PA, Cohen EP, Doffek KM, Ashley BA, Bienemann ME, Zhu YR, Adams ME, Wilson SD, Demeure MJ.

World J Surg. 2001 Jun;25(6):708-12.

PMID:
11376403

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