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Items: 29

1.

Impact of human neutralizing antibodies on antitumor efficacy of an oncolytic adenovirus in a murine model.

Tsai V, Johnson DE, Rahman A, Wen SF, LaFace D, Philopena J, Nery J, Zepeda M, Maneval DC, Demers GW, Ralston R.

Clin Cancer Res. 2004 Nov 1;10(21):7199-206.

2.

Pharmacologic indicators of antitumor efficacy for oncolytic virotherapy.

Demers GW, Johnson DE, Tsai V, Wen SF, Quijano E, Machemer T, Philopena J, Ramachandra M, Howe JA, Shabram P, Ralston R, Engler H.

Cancer Res. 2003 Jul 15;63(14):4003-8.

3.

Tumor growth inhibition by interferon-alpha using PEGylated protein or adenovirus gene transfer with constitutive or regulated expression.

Demers GW, Johnson DE, Machemer T, Looper LD, Batinica A, Beltran JC, Sugarman BJ, Howe JA.

Mol Ther. 2002 Jul;6(1):50-6.

4.

Interferon-alpha2b secretion by adenovirus-mediated gene delivery in rat, rabbit, and chimpanzee results in similar pharmacokinetic profiles.

Demers GW, Sugarman BJ, Beltran JC, Westreich LN, Ahmed CM, Lau JY, Hong Z, Lanford RE, Maneval DC.

Toxicol Appl Pharmacol. 2002 Apr 1;180(1):36-42.

PMID:
11922775
5.

Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy.

Ramachandra M, Rahman A, Zou A, Vaillancourt M, Howe JA, Antelman D, Sugarman B, Demers GW, Engler H, Johnson D, Shabram P.

Nat Biotechnol. 2001 Nov;19(11):1035-41.

PMID:
11689848
6.

Interferon alpha2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers.

Iqbal Ahmed CM, Johnson DE, Demers GW, Engler H, Howe JA, Wills KN, Wen SF, Shinoda J, Beltran J, Nodelman M, Machemer T, Maneval DC, Nagabhushan TL, Sugarman BJ.

Cancer Gene Ther. 2001 Oct;8(10):788-95.

7.

Evaluation of E1-mutant adenoviruses as conditionally replicating agents for cancer therapy.

Howe JA, Demers GW, Johnson DE, Neugebauer SE, Perry ST, Vaillancourt MT, Faha B.

Mol Ther. 2000 Nov;2(5):485-95.

8.

Calpain inhibitor 1 activates p53-dependent apoptosis in tumor cell lines.

Atencio IA, Ramachandra M, Shabram P, Demers GW.

Cell Growth Differ. 2000 May;11(5):247-53.

9.

A recombinant adenoviral vector expressing full-length human retinoblastoma susceptibility gene inhibits human tumor cell growth.

Demers GW, Harris MP, Wen SF, Engler H, Nielsen LL, Maneval DC.

Cancer Gene Ther. 1998 Jul-Aug;5(4):207-14.

PMID:
9694072
10.

Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer.

Cheney IW, Johnson DE, Vaillancourt MT, Avanzini J, Morimoto A, Demers GW, Wills KN, Shabram PW, Bolen JB, Tavtigian SV, Bookstein R.

Cancer Res. 1998 Jun 1;58(11):2331-4.

12.

Preferential radiosensitization of G1 checkpoint-deficient cells by methylxanthines.

Russell KJ, Wiens LW, Demers GW, Galloway DA, Le T, Rice GC, Bianco JA, Singer JW, Groudine M.

Int J Radiat Oncol Biol Phys. 1996 Dec 1;36(5):1099-106.

PMID:
8985032
13.

Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.

Demers GW, Espling E, Harry JB, Etscheid BG, Galloway DA.

J Virol. 1996 Oct;70(10):6862-9.

14.

Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents.

Hawkins DS, Demers GW, Galloway DA.

Cancer Res. 1996 Feb 15;56(4):892-8.

15.

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis.

Wahl AF, Donaldson KL, Fairchild C, Lee FY, Foster SA, Demers GW, Galloway DA.

Nat Med. 1996 Jan;2(1):72-9.

PMID:
8564846
16.

Analysis of human papillomavirus type 16 variants indicates establishment of persistent infection.

Xi LF, Demers GW, Koutsky LA, Kiviat NB, Kuypers J, Watts DH, Holmes KK, Galloway DA.

J Infect Dis. 1995 Sep;172(3):747-55.

PMID:
7658068
17.

Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells.

Russell KJ, Wiens LW, Demers GW, Galloway DA, Plon SE, Groudine M.

Cancer Res. 1995 Apr 15;55(8):1639-42.

19.

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

Demers GW, Foster SA, Halbert CL, Galloway DA.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4382-6.

20.
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Cell cycle checkpoint control is bypassed by human papillomavirus oncogenes.

Galloway DA, Demers GW, Foster SA, Halbert CL, Russell K.

Cold Spring Harb Symp Quant Biol. 1994;59:297-306. No abstract available.

PMID:
7587081
22.
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26.

Complete nucleotide sequence of the rabbit beta-like globin gene cluster: insights into evolution and regulation.

Hardison RC, Margot JB, Demers GW.

Prog Clin Biol Res. 1989;316B:1-17. Review.

PMID:
2694173
27.

Rabbit alpha-like and beta-like globin gene clusters: comparisons among mammalian globin gene clusters.

Hardison R, Cheng JF, Demers GW, Margot JB.

Prog Clin Biol Res. 1987;251:91-105. No abstract available.

PMID:
3432279
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