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Items: 16

1.

Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.

Prévost GP, Lonchampt MO, Holbeck S, Attoub S, Zaharevitz D, Alley M, Wright J, Brezak MC, Coulomb H, Savola A, Huchet M, Chaumeron S, Nguyen QD, Forgez P, Bruyneel E, Bracke M, Ferrandis E, Roubert P, Demarquay D, Gespach C, Kasprzyk PG.

Cancer Res. 2006 Sep 15;66(18):9227-34.

2.

BN80927: a novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo.

Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Camara J, Kasprzyk PG, Prévost G, Bigg DC.

Cancer Res. 2004 Jul 15;64(14):4942-9.

3.

A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.

Bailly C, Laine W, Baldeyrou B, Demarquay D, Huchet M, Coulomb H, Lanco C, Lavergne O, Bigg DC.

Anticancer Drug Des. 2001 Feb;16(1):27-36.

PMID:
11762642
4.

Apoptosis induced by the homocamptothecin anticancer drug BN80915 in HL-60 cells.

Lansiaux A, Facompré M, Wattez N, Hildebrand MP, Bal C, Demarquay D, Lavergne O, Bigg DC, Bailly C.

Mol Pharmacol. 2001 Sep;60(3):450-61.

5.

The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison.

Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Kasprzyk PG, Bailly C, Camara J, Bigg DC.

Anticancer Drugs. 2001 Jan;12(1):9-19.

PMID:
11272292
6.

The dual topoisomerase inhibitor, BN 80927, is highly potent against cell proliferation and tumor growth.

Huchet M, Demarquay D, Coulomb H, Kasprzyk P, Carlson M, Lauer J, Lavergne O, Bigg D.

Ann N Y Acad Sci. 2000;922:303-5. No abstract available.

PMID:
11193907
7.

The homocamptothecin, BN 80927, is a potent topoisomerase I poison and topoisomerase II catalytic inhibitor.

Demarquay D, Coulomb H, Huchet M, Lesueur-Ginot L, Camara J, Lavergne O, Bigg D.

Ann N Y Acad Sci. 2000;922:301-2. No abstract available.

PMID:
11193906
8.

Homocamptothecins: E-ring modified CPT analogues.

Lavergne O, Demarquay D, Kasprzyk PG, Bigg DC.

Ann N Y Acad Sci. 2000;922:100-11. Review.

PMID:
11193885
9.

Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins.

Lavergne O, Demarquay D, Bailly C, Lanco C, Rolland A, Huchet M, Coulomb H, Muller N, Baroggi N, Camara J, Le Breton C, Manginot E, Cazaux JB, Bigg DC.

J Med Chem. 2000 Jun 1;43(11):2285-9.

PMID:
10841808
10.

Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.

Bailly C, Lansiaux A, Dassonneville L, Demarquay D, Coulomb H, Huchet M, Lavergne O, Bigg DC.

Biochemistry. 1999 Nov 23;38(47):15556-63.

PMID:
10569939
11.

BN 80927: a novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II.

Lavergne O, Harnett J, Rolland A, Lanco C, Lesueur-Ginot L, Demarquay D, Huchet M, Coulomb H, Bigg DC.

Bioorg Med Chem Lett. 1999 Sep 6;9(17):2599-602.

PMID:
10498216
12.

Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.

Lesueur-Ginot L, Demarquay D, Kiss R, Kasprzyk PG, Dassonneville L, Bailly C, Camara J, Lavergne O, Bigg DC.

Cancer Res. 1999 Jun 15;59(12):2939-43.

13.

Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.

Lavergne O, Lesueur-Ginot L, Pla Rodas F, Kasprzyk PG, Pommier J, Demarquay D, Prévost G, Ulibarri G, Rolland A, Schiano-Liberatore AM, Harnett J, Pons D, Camara J, Bigg DC.

J Med Chem. 1998 Dec 31;41(27):5410-9.

PMID:
9876111
14.
15.

Stimulation by GH of IGF1 proforms synthesized by rabbit chondrocytes cultured with bFGF in serum-free medium.

Demarquay D, Dumontier MF, Bourguignon J, Hintz RL, Corvol MT.

Exp Cell Res. 1992 Oct;202(2):412-22.

PMID:
1397094
16.

In vitro insulin-like growth factor I interaction with cartilage cells derived from postnatal animals.

Demarquay D, Dumontier MF, Tsagris L, Bourguignon J, Nataf V, Corvol MT.

Horm Res. 1990;33(2-4):111-4; discussion 115.

PMID:
2210614

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