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Items: 1 to 50 of 135

1.

Imaging of NKT Cell Recirculation and Tissue Migration during Antimicrobial Immunity.

Delovitch TL.

Front Immunol. 2015 Jul 14;6:356. doi: 10.3389/fimmu.2015.00356. eCollection 2015. Review. No abstract available.

2.

Different subsets of natural killer T cells may vary in their roles in health and disease.

Kumar V, Delovitch TL.

Immunology. 2014 Jul;142(3):321-36. doi: 10.1111/imm.12247. Review.

3.

NKT cells stimulated by long fatty acyl chain sulfatides significantly reduce the incidence of type 1 diabetes in nonobese diabetic mice [corrected].

Subramanian L, Blumenfeld H, Tohn R, Ly D, Aguilera C, Maricic I, Mansson JE, Buschard K, Kumar V, Delovitch TL.

PLoS One. 2012;7(5):e37771. doi: 10.1371/journal.pone.0037771. Epub 2012 May 23. Erratum in: PLoS One. 2012;7(6). doi:10.1371/annotation/b5c4c567-f17b-4ebb-a6ea-d3cdff36d5ce. PLoS One. 2012;7(7). doi:10.1371/annotation/b737472b-f38a-4ef6-b10c-e052c3b66148.

4.

Structure-guided design of an invariant natural killer T cell agonist for optimum protection from type 1 diabetes in non-obese diabetic mice.

Blumenfeld HJ, Tohn R, Haeryfar SM, Liu Y, Savage PB, Delovitch TL.

Clin Exp Immunol. 2011 Oct;166(1):121-33. doi: 10.1111/j.1365-2249.2011.04454.x.

5.

Stimulation of a shorter duration in the state of anergy by an invariant natural killer T cell agonist enhances its efficiency of protection from type 1 diabetes.

Tohn R, Blumenfeld H, Haeryfar SM, Veerapen N, Besra GS, Porcelli SA, Delovitch TL.

Clin Exp Immunol. 2011 Apr;164(1):26-41. doi: 10.1111/j.1365-2249.2011.04323.x. Epub 2011 Mar 1.

6.

Engagement of glycosylphosphatidylinositol-anchored proteins results in enhanced mouse and human invariant natural killer T cell responses.

Mannik LA, Chin-Yee I, Sharif S, Van Kaer L, Delovitch TL, Haeryfar SM.

Immunology. 2011 Mar;132(3):361-75. doi: 10.1111/j.1365-2567.2010.03369.x. Epub 2010 Nov 11.

7.

Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism.

Meagher C, Beilke J, Arreaza G, Mi QS, Chen W, Salojin K, Horst N, Cruikshank WW, Delovitch TL.

Diabetes. 2010 Nov;59(11):2862-71. doi: 10.2337/db09-0131. Epub 2010 Aug 6.

8.

An alpha-galactosylceramide C20:2 N-acyl variant enhances anti-inflammatory and regulatory T cell-independent responses that prevent type 1 diabetes.

Ly D, Tohn R, Rubin B, Blumenfeld H, Besra GS, Veerapen N, Porcelli SA, Delovitch TL.

Clin Exp Immunol. 2010 May;160(2):185-98. doi: 10.1111/j.1365-2249.2009.04074.x. Epub 2009 Dec 15.

9.
10.

Decreased renal ischemia-reperfusion injury by IL-16 inactivation.

Wang S, Diao H, Guan Q, Cruikshank WW, Delovitch TL, Jevnikar AM, Du C.

Kidney Int. 2008 Feb;73(3):318-26. Epub 2007 Nov 14.

11.

The "End of the beginning" of the immunobiology of iNKT cells in health and disease.

Delovitch TL.

Int Rev Immunol. 2007 Jan-Apr;26(1-2):1-3. No abstract available.

PMID:
17454261
12.

CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.

Meagher C, Arreaza G, Peters A, Strathdee CA, Gilbert PA, Mi QS, Santamaria P, Dekaban GA, Delovitch TL.

Diabetes. 2007 Mar;56(3):809-17.

13.

Characterization of PAF-AH Ib1 in NOD mice: PAF-AH may not be a candidate gene of the diabetes susceptibility Idd4.1 locus.

Mi QS, Zhou L, Grattan M, Wang ZZ, Sivilotti M, She JX, Delovitch TL.

Ann N Y Acad Sci. 2006 Oct;1079:147-52.

PMID:
17130546
14.

The autoimmune regulator (Aire) controls iNKT cell development and maturation.

Mi QS, Deng ZB, Joshi SK, Wang ZZ, Zhou L, Eckenrode S, Joshi R, Ly D, Yi B, Delovitch TL, She JX.

Nat Med. 2006 Sep;12(9):1100. No abstract available.

PMID:
16960577
15.

Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells.

Ly D, Mi QS, Hussain S, Delovitch TL.

J Immunol. 2006 Sep 15;177(6):3695-704.

16.

The autoimmune regulator (Aire) controls iNKT cell development and maturation.

Mi QS, Deng ZB, Joshi SK, Wang ZZ, Zhou L, Eckenrode S, Joshi R, Ly D, Yi B, Delovitch TL, She JX.

Nat Med. 2006 Jun;12(6):624-6. Epub 2006 May 28. Retraction in: Mi QS, Deng ZB, Joshi SK, Wang ZZ, Zhou L, Eckenrode S, Joshi R, Ly D, Yi B, Delovitch TL, She JX. Nat Med. 2006 Sep;12(9):1100.

PMID:
16732280
17.

A defect in lineage fate decision during fetal thymic invariant NKT cell development may regulate susceptibility to type 1 diabetes.

Wagner MJ, Hussain S, Mehan M, Verdi JM, Delovitch TL.

J Immunol. 2005 Jun 1;174(11):6764-71.

18.

Role of regulatory invariant CD1d-restricted natural killer T-cells in protection against type 1 diabetes.

Hussain S, Wagner M, Ly D, Delovitch TL.

Immunol Res. 2005;31(3):177-88. Review.

PMID:
15888910
20.
23.

Insulin-like growth factor (IGF)-I/IGF-binding protein-3 complex: therapeutic efficacy and mechanism of protection against type 1 diabetes.

Chen W, Salojin KV, Mi QS, Grattan M, Meagher TC, Zucker P, Delovitch TL.

Endocrinology. 2004 Feb;145(2):627-38. Epub 2003 Nov 14.

PMID:
14617576
24.

CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes.

Mi QS, Meagher C, Delovitch TL.

Novartis Found Symp. 2003;252:146-60; discussion 160-4, 203-10. Review.

PMID:
14609217
25.

Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice.

Mi QS, Ly D, Lamhamedi-Cherradi SE, Salojin KV, Zhou L, Grattan M, Meagher C, Zucker P, Chen YH, Nagle J, Taub D, Delovitch TL.

Diabetes. 2003 Aug;52(8):1967-75.

26.

Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice.

Arreaza G, Salojin K, Yang W, Zhang J, Gill B, Mi QS, Gao JX, Meagher C, Cameron M, Delovitch TL.

Clin Immunol. 2003 May;107(2):103-15.

PMID:
12763479
27.

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity.

Wilson SB, Delovitch TL.

Nat Rev Immunol. 2003 Mar;3(3):211-22. Review.

PMID:
12658269
28.

Cytokines and chemokines in the pathogenesis of murine type 1 diabetes.

Meagher C, Sharif S, Hussain S, Cameron MJ, Arreaza GA, Delovitch TL.

Adv Exp Med Biol. 2003;520:133-58. Review. No abstract available.

PMID:
12613577
29.

Regulation of autoimmune disease by natural killer T cells.

Sharif S, Arreaza GA, Zucker P, Mi QS, Delovitch TL.

J Mol Med (Berl). 2002 May;80(5):290-300. Epub 2002 Apr 11. Review.

PMID:
12021841
30.

Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes.

Sharif S, Arreaza GA, Zucker P, Delovitch TL.

Ann N Y Acad Sci. 2002 Apr;958:77-88. Review.

PMID:
12021086
32.

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes.

Chen W, Bergerot I, Elliott JF, Harrison LC, Abiru N, Eisenbarth GS, Delovitch TL.

J Immunol. 2001 Nov 1;167(9):4926-35.

33.

Regulation of immune responses by natural killer T cells.

Sharif S, Delovitch TL.

Arch Immunol Ther Exp (Warsz). 2001;49 Suppl 1:S23-31. Review.

PMID:
11603866
34.

Role of regulatory T cells in the pathogenesis of autoimmune diabetes.

Arreaza GA, Sharif S, Cameron MJ, Chen W, Delovitch TL.

Curr Dir Autoimmun. 2001;4:308-32. Review. No abstract available.

PMID:
11569408
35.

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes.

Sharif S, Arreaza GA, Zucker P, Mi QS, Sondhi J, Naidenko OV, Kronenberg M, Koezuka Y, Delovitch TL, Gombert JM, Leite-De-Moraes M, Gouarin C, Zhu R, Hameg A, Nakayama T, Taniguchi M, Lepault F, Lehuen A, Bach JF, Herbelin A.

Nat Med. 2001 Sep;7(9):1057-62.

PMID:
11533711
37.

Immune mechanisms that regulate susceptibility to autoimmune type I diabetes.

Singh B, Delovitch TL.

Clin Rev Allergy Immunol. 2000 Dec;19(3):247-64. Review. No abstract available.

PMID:
11138408
38.
39.

Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes.

Cameron MJ, Strathdee CA, Holmes KD, Arreaza GA, Dekaban GA, Delovitch TL.

Hum Gene Ther. 2000 Aug 10;11(12):1647-56.

PMID:
10954899
40.

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

Cameron MJ, Arreaza GA, Grattan M, Meagher C, Sharif S, Burdick MD, Strieter RM, Cook DN, Delovitch TL.

J Immunol. 2000 Jul 15;165(2):1102-10.

41.

Preferential proliferation and differentiation of double-positive thymocytes into CD8(+) single-positive thymocytes in a novel cell culture medium.

Gao JX, Zhang J, Awaraji C, Bhatia M, Jevnikar A, Singh B, Bell D, Delovitch TL.

Cell Immunol. 2000 May 25;202(1):41-53.

PMID:
10873305
42.

Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase.

Zhang J, Gao JX, Salojin K, Shao Q, Grattan M, Meagher C, Laird DW, Delovitch TL.

J Exp Med. 2000 Mar 20;191(6):1017-30.

43.

ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells.

Salojin KV, Zhang J, Meagher C, Delovitch TL.

J Biol Chem. 2000 Feb 25;275(8):5966-75.

44.
45.
46.

p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells.

Zhang J, Salojin KV, Gao JX, Cameron MJ, Bergerot I, Delovitch TL.

J Immunol. 1999 Apr 1;162(7):3819-29.

47.

Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.

Hill DJ, Petrik J, Arany E, McDonald TJ, Delovitch TL.

J Endocrinol. 1999 Apr;161(1):153-65.

PMID:
10194539
48.

T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease.

Salojin KV, Zhang J, Madrenas J, Delovitch TL.

Immunol Today. 1998 Oct;19(10):468-73.

PMID:
9785671
49.

TCR alpha beta chains associate with the plasma membrane independently of CD3 and TCR zeta chains in murine primary T cells.

Zhang J, Salojin K, Gao JX, Cameron M, Geisler C, Delovitch TL.

J Immunol. 1998 Sep 15;161(6):2930-7.

50.

Failure in immune regulation begets IDDM in NOD mice.

Cameron MJ, Meagher C, Delovitch TL.

Diabetes Metab Rev. 1998 Jun;14(2):177-85. Review.

PMID:
9679670

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