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Items: 1 to 50 of 258

1.

Identification of Plasmodium falciparum and host factors associated with cerebral malaria: description of the protocol for a prospective, case-control study in Benin (NeuroCM).

Joste V, Maurice L, Bertin GI, Aubouy A, Boumédiène F, Houzé S, Ajzenberg D, Argy N, Massougbodji A, Dossou-Dagba I, Alao MJ, Cot M, Deloron P, Faucher JF; NeuroCM group.

BMJ Open. 2019 May 28;9(5):e027378. doi: 10.1136/bmjopen-2018-027378.

2.

First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria.

Mordmüller B, Sulyok M, Egger-Adam D, Resende M, de Jongh WA, Jensen MH, Smedegaard HH, Ditlev SB, Soegaard M, Poulsen L, Dyring C, Calle CL, Knoblich A, Ibáñez J, Esen M, Deloron P, Ndam N, Issifou S, Houard S, Howard RF, Reed SG, Leroy O, Luty AJF, Theander TG, Kremsner PG, Salanti A, Nielsen MA.

Clin Infect Dis. 2019 Jan 10. doi: 10.1093/cid/ciy1140. [Epub ahead of print]

PMID:
30629148
3.

Dynamics of Plasmodium falciparum gametocyte carriage in pregnant women under intermittent preventive treatment with sulfadoxine-pyrimethamine in Benin.

Jafari-Guemouri S, Dhiab J, Massougbodji A, Deloron P, Tuikue NN.

Malar J. 2018 Oct 11;17(1):356. doi: 10.1186/s12936-018-2498-8.

4.

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis.

Kloprogge F, Workman L, Borrmann S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Aweeka F, Parikh S, Mwai L, Davis TME, Karunajeewa H, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux S, Price RN, Karbwang J, Ezzet F, Bakshi R, Stepniewska K, White NJ, Guerin PJ, Barnes KI, Tarning J.

PLoS Med. 2018 Jun 12;15(6):e1002579. doi: 10.1371/journal.pmed.1002579. eCollection 2018 Jun.

5.

Persistent Plasmodium falciparum Infection in Women With an Intent to Become Pregnant as a Risk Factor for Pregnancy-associated Malaria.

Tuikue Ndam N, Tornyigah B, Dossou AY, Escriou G, Nielsen MA, Salanti A, Issifou S, Massougbodji A, Chippaux JP, Deloron P.

Clin Infect Dis. 2018 Nov 28;67(12):1890-1896. doi: 10.1093/cid/ciy380.

PMID:
29733338
6.

Determinants of primary healthcare seeking behaviours for children during the first 18 months of life in Benin.

Brembilla A, Faucher JF, Garcia A, Koura KG, Deloron P, Parmentier AL, Pierrat C, Cottrell G, Mauny F.

Int Health. 2018 Jul 1;10(4):237-245. doi: 10.1093/inthealth/ihy020.

PMID:
29659852
7.

Submicroscopic placental infection by non-falciparum Plasmodium spp.

Doritchamou JYA, Akuffo RA, Moussiliou A, Luty AJF, Massougbodji A, Deloron P, Tuikue Ndam NG.

PLoS Negl Trop Dis. 2018 Feb 12;12(2):e0006279. doi: 10.1371/journal.pntd.0006279. eCollection 2018 Feb.

8.

Matched Placental and Circulating Plasmodium falciparum Parasites are Genetically Homologous at the var2csa ID1-DBL2X Locus by Deep Sequencing.

Waltmann A, Patel JC, Thwai KL, Hathaway NJ, Parobek CM, Massougbodji A, Fievet N, Bailey JA, Deloron P, Juliano JJ, Ndam NT, Meshnick SR.

Am J Trop Med Hyg. 2018 Jan;98(1):77-82. doi: 10.4269/ajtmh.17-0529.

9.

PFI1785w: A highly conserved protein associated with pregnancy associated malaria.

Kamaliddin C, Salnot V, Leduc M, Ezinmegnon S, Broussard C, Fievet N, Deloron P, Guillonneau F, Bertin GI.

PLoS One. 2017 Nov 9;12(11):e0187817. doi: 10.1371/journal.pone.0187817. eCollection 2017.

10.

Plasmodium falciparum Infection Early in Pregnancy has Profound Consequences for Fetal Growth.

Schmiegelow C, Matondo S, Minja DTR, Resende M, Pehrson C, Nielsen BB, Olomi R, Nielsen MA, Deloron P, Salanti A, Lusingu J, Theander TG.

J Infect Dis. 2017 Dec 19;216(12):1601-1610. doi: 10.1093/infdis/jix530.

PMID:
29029247
11.

Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1.

Tuikue Ndam N, Moussiliou A, Lavstsen T, Kamaliddin C, Jensen ATR, Mama A, Tahar R, Wang CW, Jespersen JS, Alao JM, Gamain B, Theander TG, Deloron P.

J Infect Dis. 2017 Jun 15;215(12):1918-1925. doi: 10.1093/infdis/jix230.

PMID:
28863469
12.

Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade.

Patel JC, Hathaway NJ, Parobek CM, Thwai KL, Madanitsa M, Khairallah C, Kalilani-Phiri L, Mwapasa V, Massougbodji A, Fievet N, Bailey JA, Ter Kuile FO, Deloron P, Engel SM, Taylor SM, Juliano JJ, Tuikue Ndam N, Meshnick SR.

Sci Rep. 2017 Aug 11;7(1):7768. doi: 10.1038/s41598-017-04737-y.

13.

Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co-cultured with Plasmodium falciparum field isolates.

Essone JCBB, N'Dilimabaka N, Ondzaga J, Lekana-Douki JB, Mba DN, Deloron P, Mazier D, Gay F, Touré Ndouo FS.

BMC Infect Dis. 2017 Jun 27;17(1):454. doi: 10.1186/s12879-017-2552-0.

14.

Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae.

Gbédandé K, Fievet N, Viwami F, Ezinmegnon S, Issifou S, Chippaux JP, Dossou Y, Moutairou K, Massougbodji A, Ndam N, de Jongh WA, Søgaard TMM, Salanti A, Nielsen MA, Esen M, Mordmüller B, Deloron P, Luty AJF; Multi-centre research paper.

Vaccine. 2017 Jun 14;35(27):3474-3481. doi: 10.1016/j.vaccine.2017.05.027. Epub 2017 May 17.

PMID:
28527688
15.

Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria.

Tétard M, Milet J, Dechavanne S, Fievet N, Dorin-Semblat D, Elion J, Fairhurst RM, Deloron P, Tuikue-Ndam N, Gamain B.

Sci Rep. 2017 May 3;7(1):1414. doi: 10.1038/s41598-017-01495-9.

16.

Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West Africa.

Day KP, Artzy-Randrup Y, Tiedje KE, Rougeron V, Chen DS, Rask TS, Rorick MM, Migot-Nabias F, Deloron P, Luty AJF, Pascual M.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4103-E4111. doi: 10.1073/pnas.1613018114. Epub 2017 May 1.

17.

Influence of host factors and parasite biomass on the severity of imported Plasmodium falciparum malaria.

Argy N, Kendjo E, Augé-Courtoi C, Cojean S, Clain J, Houzé P, Thellier M, Hubert V, Deloron P, Houzé S; CNRP study group.

PLoS One. 2017 Apr 14;12(4):e0175328. doi: 10.1371/journal.pone.0175328. eCollection 2017.

18.

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon.

Ndam NT, Basco LK, Ngane VF, Ayouba A, Ngolle EM, Deloron P, Peeters M, Tahar R.

Malar J. 2017 Mar 27;16(1):130. doi: 10.1186/s12936-017-1783-2.

19.

Usefulness of a biomarker to identify placental dysfunction in the context of malaria.

Gueneuc A, Deloron P, Bertin GI.

Malar J. 2017 Jan 3;16(1):11. doi: 10.1186/s12936-016-1664-0. Review.

20.

Preferential expression of domain cassettes 4, 8 and 13 of Plasmodium falciparum erythrocyte membrane protein 1 in severe malaria imported in France.

Argy N, Bertin GI, Milet J, Hubert V, Clain J, Cojean S, Houzé P, Tuikue-Ndam N, Kendjo E, Deloron P, Houzé S; CNRP Study Group.

Clin Microbiol Infect. 2017 Mar;23(3):211.e1-211.e4. doi: 10.1016/j.cmi.2016.10.012. Epub 2016 Oct 20.

21.

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses.

Gbédandé K, Cottrell G, Vianou B, Ibitokou S, Fernando A, Troye-Blomberg M, Salanti A, Moutairou K, Massougbodji A, Ndam NT, Deloron P, Luty AJ, Fievet N.

Malar J. 2016 Sep 21;15(1):485.

22.

Fetal Growth Restriction Is Associated With Malaria in Pregnancy: A Prospective Longitudinal Study in Benin.

Briand V, Saal J, Ghafari C, Huynh BT, Fievet N, Schmiegelow C, Massougbodji A, Deloron P, Zeitlin J, Cot M.

J Infect Dis. 2016 Aug 1;214(3):417-25. doi: 10.1093/infdis/jiw158. Epub 2016 Apr 18.

PMID:
27389349
23.

Proteomic analysis of Plasmodium falciparum parasites from patients with cerebral and uncomplicated malaria.

Bertin GI, Sabbagh A, Argy N, Salnot V, Ezinmegnon S, Agbota G, Ladipo Y, Alao JM, Sagbo G, Guillonneau F, Deloron P.

Sci Rep. 2016 Jun 1;6:26773. doi: 10.1038/srep26773.

24.

Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum.

Bandje K, Naissant B, Bigey P, Lohezic M, Vayssières M, Blaud M, Kermasson L, Lopez-Rubio JJ, Langsley G, Lavazec C, Deloron P, Merckx A.

Malar J. 2016 Apr 29;15:248. doi: 10.1186/s12936-016-1275-9.

25.

Antibiotics usage in infants during the first 18 months of life in Benin: a population-based cohort study.

Brembilla A, Mauny F, Garcia A, Koura KG, Deloron P, Faucher JF.

Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):681-9. doi: 10.1007/s10096-016-2587-y. Epub 2016 Feb 10.

PMID:
26864042
26.

Computational Fluid Dynamic Simulations of Maternal Circulation: Wall Shear Stress in the Human Placenta and Its Biological Implications.

Lecarpentier E, Bhatt M, Bertin GI, Deloison B, Salomon LJ, Deloron P, Fournier T, Barakat AI, Tsatsaris V.

PLoS One. 2016 Jan 27;11(1):e0147262. doi: 10.1371/journal.pone.0147262. eCollection 2016.

27.

Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding.

Nunes-Silva S, Dechavanne S, Moussiliou A, Pstrąg N, Semblat JP, Gangnard S, Tuikue-Ndam N, Deloron P, Chêne A, Gamain B.

Malar J. 2016 Jan 11;15:22. doi: 10.1186/s12936-015-1061-0. No abstract available.

28.

Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding.

Nunes-Silva S, Dechavanne S, Moussiliou A, Pstrąg N, Semblat JP, Gangnard S, Tuikue-Ndam N, Deloron P, Chêne A, Gamain B.

Malar J. 2015 Dec 8;14:493. doi: 10.1186/s12936-015-1008-5. Erratum in: Malar J. 2016;15:22.

29.

Infants' Peripheral Blood Lymphocyte Composition Reflects Both Maternal and Post-Natal Infection with Plasmodium falciparum.

Nouatin O, Gbédandé K, Ibitokou S, Vianou B, Houngbegnon P, Ezinmegnon S, Borgella S, Akplogan C, Cottrell G, Varani S, Massougbodji A, Moutairou K, Troye-Blomberg M, Deloron P, Luty AJ, Fievet N.

PLoS One. 2015 Nov 18;10(11):e0139606. doi: 10.1371/journal.pone.0139606. eCollection 2015.

30.

Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA.

Doritchamou J, Sabbagh A, Jespersen JS, Renard E, Salanti A, Nielsen MA, Deloron P, Tuikue Ndam N.

PLoS One. 2015 Sep 22;10(9):e0137695. doi: 10.1371/journal.pone.0137695. eCollection 2015.

31.

Nrf2-driven CD36 and HO-1 gene expression in circulating monocytes correlates with favourable clinical outcome in pregnancy-associated malaria.

Aubouy A, Olagnier D, Bertin G, Ezinmegnon S, Majorel C, Mimar S, Massougbodji A, Deloron P, Pipy B, Coste A.

Malar J. 2015 Sep 18;14:358. doi: 10.1186/s12936-015-0888-8.

32.

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine.

Nielsen MA, Resende M, de Jongh WA, Ditlev SB, Mordmüller B, Houard S, Ndam NT, Agerbæk MØ, Hamborg M, Massougbodji A, Issifou S, Strøbæk A, Poulsen L, Leroy O, Kremsner PG, Chippaux JP, Luty AJ, Deloron P, Theander TG, Dyring C, Salanti A.

PLoS One. 2015 Sep 1;10(9):e0135406. doi: 10.1371/journal.pone.0135406. eCollection 2015.

33.

Immunoglobulin response to Plasmodium falciparum RESA proteins in uncomplicated and severe malaria.

Badaut C, Guyonnet L, Milet J, Renard E, Durand R, Viwami F, Sagbo G, Layla F, Deloron P, Bonnefoy S, Migot-Nabias F.

Malar J. 2015 Jul 16;14:278. doi: 10.1186/s12936-015-0799-8.

34.

Developing vaccines to prevent malaria in pregnant women.

Tuikue-Ndam N, Deloron P.

Expert Opin Biol Ther. 2015;15(8):1173-82. doi: 10.1517/14712598.2015.1049595. Epub 2015 Jun 8. Review.

PMID:
26051589
35.

Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin.

Ndam NT, Denoeud-Ndam L, Doritchamou J, Viwami F, Salanti A, Nielsen MA, Fievet N, Massougbodji A, Luty AJ, Deloron P.

Emerg Infect Dis. 2015 May;21(5):813-23. doi: 10.3201/eid2105.141626.

36.

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.

WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group, Adjuik MA, Allan R, Anvikar AR, Ashley EA, Ba MS, Barennes H, Barnes KI, Bassat Q, Baudin E, Björkman A, Bompart F, Bonnet M, Borrmann S, Brasseur P, Bukirwa H, Checchi F, Cot M, Dahal P, D'Alessandro U, Deloron P, Desai M, Diap G, Djimde AA, Dorsey G, Doumbo OK, Espié E, Etard JF, Fanello CI, Faucher JF, Faye B, Flegg JA, Gaye O, Gething PW, González R, Grandesso F, Guerin PJ, Guthmann JP, Hamour S, Hasugian AR, Hay SI, Humphreys GS, Jullien V, Juma E, Kamya MR, Karema C, Kiechel JR, Kremsner PG, Krishna S, Lameyre V, Ibrahim LM, Lee SJ, Lell B, Mårtensson A, Massougbodji A, Menan H, Ménard D, Menéndez C, Meremikwu M, Moreira C, Nabasumba C, Nambozi M, Ndiaye JL, Nikiema F, Nsanzabana C, Ntoumi F, Ogutu BR, Olliaro P, Osorio L, Ouédraogo JB, Penali LK, Pene M, Pinoges L, Piola P, Price RN, Roper C, Rosenthal PJ, Rwagacondo CE, Same-Ekobo A, Schramm B, Seck A, Sharma B, Sibley CH, Sinou V, Sirima SB, Smith JJ, Smithuis F, Somé FA, Sow D, Staedke SG, Stepniewska K, Swarthout TD, Sylla K, Talisuna AO, Tarning J, Taylor WR, Temu EA, Thwing JI, Tjitra E, Tine RC, Tinto H, Vaillant MT, Valecha N, Van den Broek I, White NJ, Yeka A, Zongo I.

BMC Med. 2015 Mar 31;13:66. doi: 10.1186/s12916-015-0301-z.

37.

Parity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria.

Dechavanne S, Srivastava A, Gangnard S, Nunes-Silva S, Dechavanne C, Fievet N, Deloron P, Chêne A, Gamain B.

Infect Immun. 2015 Jun;83(6):2466-74. doi: 10.1128/IAI.03116-14. Epub 2015 Mar 30.

38.

Submicroscopic Plasmodium falciparum Infections Are Associated With Maternal Anemia, Premature Births, and Low Birth Weight.

Cottrell G, Moussiliou A, Luty AJ, Cot M, Fievet N, Massougbodji A, Deloron P, Tuikue Ndam N.

Clin Infect Dis. 2015 May 15;60(10):1481-8. doi: 10.1093/cid/civ122. Epub 2015 Feb 18.

PMID:
25694651
39.

Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers.

Almelli T, Nuel G, Bischoff E, Aubouy A, Elati M, Wang CW, Dillies MA, Coppée JY, Ayissi GN, Basco LK, Rogier C, Ndam NT, Deloron P, Tahar R.

PLoS One. 2014 Dec 5;9(12):e114401. doi: 10.1371/journal.pone.0114401. eCollection 2014.

40.

High plasma levels of soluble endothelial protein C receptor are associated with increased mortality among children with cerebral malaria in Benin.

Moussiliou A, Alao MJ, Denoeud-Ndam L, Tahar R, Ezimegnon S, Sagbo G, Amoussou A, Luty AJ, Deloron P, Tuikue Ndam N.

J Infect Dis. 2015 May 1;211(9):1484-8. doi: 10.1093/infdis/jiu661. Epub 2014 Nov 25.

PMID:
25425698
41.

Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria.

Almelli T, Ndam NT, Ezimegnon S, Alao MJ, Ahouansou C, Sagbo G, Amoussou A, Deloron P, Tahar R.

Malar J. 2014 Aug 25;13:333. doi: 10.1186/1475-2875-13-333.

42.

Placental cytokine and chemokine profiles reflect pregnancy outcomes in women exposed to Plasmodium falciparum infection.

Chêne A, Briand V, Ibitokou S, Dechavanne S, Massougbodji A, Deloron P, Luty AJ, Gamain B, Fievet N.

Infect Immun. 2014 Sep;82(9):3783-9. doi: 10.1128/IAI.01922-14. Epub 2014 Jun 23.

43.

Dynamics in the cytoadherence phenotypes of Plasmodium falciparum infected erythrocytes isolated during pregnancy.

Doritchamou J, Sossou-tchatcha S, Cottrell G, Moussiliou A, Hounton Houngbeme C, Massougbodji A, Deloron P, Ndam NT.

PLoS One. 2014 Jun 6;9(6):e98577. doi: 10.1371/journal.pone.0098577. eCollection 2014.

44.

Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria.

Bordbar B, Tuikue Ndam N, Renard E, Jafari-Guemouri S, Tavul L, Jennison C, Gnidehou S, Tahar R, Gamboa D, Bendezu J, Menard D, Barry AE, Deloron P, Sabbagh A.

Infect Genet Evol. 2014 Jul;25:81-92. doi: 10.1016/j.meegid.2014.04.010. Epub 2014 Apr 21.

PMID:
24768682
45.

Submicroscopic infections with Plasmodium falciparum during pregnancy and their association with circulating cytokine, chemokine, and cellular profiles.

Ibitokou SA, Boström S, Brutus L, Tuikue Ndam N, Vianou B, Agbowaï C, Amadoudji Zin M, Huynh BT, Massougbodji A, Deloron P, Troye-Blomberg M, Fievet N, Luty AJ.

Clin Vaccine Immunol. 2014 Jun;21(6):859-66. doi: 10.1128/CVI.00009-14. Epub 2014 Apr 9. Erratum in: Clin Vaccine Immunol. 2014 Oct;21(10):1468.

46.

Impact of pregnancy-associated malaria on infant malaria infection in southern Benin.

Borgella S, Fievet N, Huynh BT, Ibitokou S, Hounguevou G, Affedjou J, Sagbo JC, Houngbegnon P, Guezo-Mévo B, Massougbodji A, Luty AJ, Cot M, Deloron P.

PLoS One. 2013 Nov 13;8(11):e80624. doi: 10.1371/journal.pone.0080624. eCollection 2013.

47.

Epistatic Interactions between apolipoprotein E and hemoglobin S Genes in regulation of malaria parasitemia.

Rougeron V, Woods CM, Tiedje KE, Bodeau-Livinec F, Migot-Nabias F, Deloron P, Luty AJ, Fowkes FJ, Day KP.

PLoS One. 2013 Oct 8;8(10):e76924. doi: 10.1371/journal.pone.0076924. eCollection 2013.

48.

Plasmodium falciparum Polymorphisms associated with ex vivo drug susceptibility and clinical effectiveness of artemisinin-based combination therapies in Benin.

Dahlström S, Aubouy A, Maïga-Ascofaré O, Faucher JF, Wakpo A, Ezinmègnon S, Massougbodji A, Houzé P, Kendjo E, Deloron P, Le Bras J, Houzé S.

Antimicrob Agents Chemother. 2014;58(1):1-10. doi: 10.1128/AAC.01790-12. Epub 2013 Oct 7.

49.

Plasmodium vivax malaria during pregnancy, Bolivia.

Brutus L, Santalla J, Schneider D, Avila JC, Deloron P.

Emerg Infect Dis. 2013 Oct;19(10):1605-11. doi: 10.3201/eid1910.130308.

50.

Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA.

Doritchamou J, Bigey P, Nielsen MA, Gnidehou S, Ezinmegnon S, Burgain A, Massougbodji A, Deloron P, Salanti A, Ndam NT.

Vaccine. 2013 Sep 23;31(41):4516-22. doi: 10.1016/j.vaccine.2013.07.072. Epub 2013 Aug 9.

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