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Items: 1 to 50 of 51

1.

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis.

Nguyen PC, Delorme V, Bénarouche A, Guy A, Landry V, Audebert S, Pophillat M, Camoin L, Crauste C, Galano JM, Durand T, Brodin P, Canaan S, Cavalier JF.

Bioorg Chem. 2018 Aug 29;81:414-424. doi: 10.1016/j.bioorg.2018.08.025. [Epub ahead of print]

PMID:
30212765
2.

Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains.

Hameed HMA, Islam MM, Chhotaray C, Wang C, Liu Y, Tan Y, Li X, Tan S, Delorme V, Yew WW, Liu J, Zhang T.

Front Cell Infect Microbiol. 2018 Apr 10;8:114. doi: 10.3389/fcimb.2018.00114. eCollection 2018. Review.

3.

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

Costa-Gouveia J, Pancani E, Jouny S, Machelart A, Delorme V, Salzano G, Iantomasi R, Piveteau C, Queval CJ, Song OR, Flipo M, Deprez B, Saint-André JP, Hureaux J, Majlessi L, Willand N, Baulard A, Brodin P, Gref R.

Sci Rep. 2018 May 10;8(1):7596. doi: 10.1038/s41598-018-25177-2.

4.

Mycobacterium tuberculosis Infection and Innate Responses in a New Model of Lung Alveolar Macrophages.

Woo M, Wood C, Kwon D, Park KP, Fejer G, Delorme V.

Front Immunol. 2018 Mar 12;9:438. doi: 10.3389/fimmu.2018.00438. eCollection 2018.

5.

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

Song OR, Queval CJ, Iantomasi R, Delorme V, Marion S, Veyron-Churlet R, Werkmeister E, Popoff M, Ricard I, Jouny S, Deboosere N, Lafont F, Baulard A, Yeramian E, Marsollier L, Hoffmann E, Brodin P.

EMBO Rep. 2018 Jan;19(1):29-42. doi: 10.15252/embr.201744371. Epub 2017 Nov 15.

PMID:
29141986
6.

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling.

Queval CJ, Song OR, Carralot JP, Saliou JM, Bongiovanni A, Deloison G, Deboosère N, Jouny S, Iantomasi R, Delorme V, Debrie AS, Park SJ, Gouveia JC, Tomavo S, Brosch R, Yoshimura A, Yeramian E, Brodin P.

Cell Rep. 2017 Sep 26;20(13):3188-3198. doi: 10.1016/j.celrep.2017.08.101.

7.

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

Nguyen PC, Delorme V, Bénarouche A, Martin BP, Paudel R, Gnawali GR, Madani A, Puppo R, Landry V, Kremer L, Brodin P, Spilling CD, Cavalier JF, Canaan S.

Sci Rep. 2017 Sep 18;7(1):11751. doi: 10.1038/s41598-017-11843-4.

8.

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

Costa-Gouveia J, Pancani E, Jouny S, Machelart A, Delorme V, Salzano G, Iantomasi R, Piveteau C, Queval CJ, Song OR, Flipo M, Deprez B, Saint-André JP, Hureaux J, Majlessi L, Willand N, Baulard A, Brodin P, Gref R.

Sci Rep. 2017 Jul 14;7(1):5390. doi: 10.1038/s41598-017-05453-3. Erratum in: Sci Rep. 2018 May 10;8(1):7596.

9.

Phenotypic assays for Mycobacterium tuberculosis infection.

Song OR, Deboosere N, Delorme V, Queval CJ, Deloison G, Werkmeister E, Lafont F, Baulard A, Iantomasi R, Brodin P.

Cytometry A. 2017 Oct;91(10):983-994. doi: 10.1002/cyto.a.23129. Epub 2017 May 19.

PMID:
28544095
10.

Efflux Attenuates the Antibacterial Activity of Q203 in Mycobacterium tuberculosis.

Jang J, Kim R, Woo M, Jeong J, Park DE, Kim G, Delorme V.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02637-16. doi: 10.1128/AAC.02637-16. Print 2017 Jul.

11.

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.

Nikiforov PO, Blaszczyk M, Surade S, Boshoff HI, Sajid A, Delorme V, Deboosere N, Brodin P, Baulard AR, Barry CE 3rd, Blundell TL, Abell C.

ACS Chem Biol. 2017 May 19;12(5):1390-1396. doi: 10.1021/acschembio.7b00091. Epub 2017 Apr 5.

12.

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

Blondiaux N, Moune M, Desroses M, Frita R, Flipo M, Mathys V, Soetaert K, Kiass M, Delorme V, Djaout K, Trebosc V, Kemmer C, Wintjens R, Wohlkönig A, Antoine R, Huot L, Hot D, Coscolla M, Feldmann J, Gagneux S, Locht C, Brodin P, Gitzinger M, Déprez B, Willand N, Baulard AR.

Science. 2017 Mar 17;355(6330):1206-1211. doi: 10.1126/science.aag1006. Epub 2017 Mar 16.

PMID:
28302858
13.

High-Content Screening of Raw Actinomycete Extracts for the Identification of Antituberculosis Activities.

Heo J, Nam J, Jang J, Shum D, Radu C, Cheng J, Lee H, Suh JW, Delorme V.

SLAS Discov. 2017 Feb;22(2):144-154. doi: 10.1177/1087057116675887. Epub 2016 Nov 4.

PMID:
27810952
14.

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.

Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC.

Mol Microbiol. 2017 Jan;103(1):13-25. doi: 10.1111/mmi.13535. Epub 2016 Oct 29.

15.

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection.

Queval CJ, Song OR, Deboosère N, Delorme V, Debrie AS, Iantomasi R, Veyron-Churlet R, Jouny S, Redhage K, Deloison G, Baulard A, Chamaillard M, Locht C, Brodin P.

Sci Rep. 2016 Jul 7;6:29297. doi: 10.1038/srep29297.

16.

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters.

Nikiforov PO, Surade S, Blaszczyk M, Delorme V, Brodin P, Baulard AR, Blundell TL, Abell C.

Org Biomol Chem. 2016 Feb 21;14(7):2318-26. doi: 10.1039/c5ob02630j. Epub 2016 Jan 25.

17.

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays.

Delorme V, Song OR, Baulard A, Brodin P.

Methods Mol Biol. 2015;1285:387-411. doi: 10.1007/978-1-4939-2450-9_24.

PMID:
25779330
18.

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.

Neres J, Hartkoorn RC, Chiarelli LR, Gadupudi R, Pasca MR, Mori G, Venturelli A, Savina S, Makarov V, Kolly GS, Molteni E, Binda C, Dhar N, Ferrari S, Brodin P, Delorme V, Landry V, de Jesus Lopes Ribeiro AL, Farina D, Saxena P, Pojer F, Carta A, Luciani R, Porta A, Zanoni G, De Rossi E, Costi MP, Riccardi G, Cole ST.

ACS Chem Biol. 2015 Mar 20;10(3):705-14. doi: 10.1021/cb5007163. Epub 2014 Dec 9.

PMID:
25427196
19.

Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification.

Delorme V, Raux B, Puppo R, Leclaire J, Cavalier JF, Marc S, Kamarajugadda PK, Buono G, Fotiadu F, Canaan S, Carrière F.

Biochimie. 2014 Dec;107 Pt A:124-34. doi: 10.1016/j.biochi.2014.07.015. Epub 2014 Jul 24.

PMID:
25064360
20.

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening.

Queval CJ, Song OR, Delorme V, Iantomasi R, Veyron-Churlet R, Deboosère N, Landry V, Baulard A, Brodin P.

J Vis Exp. 2014 Jan 17;(83):e51114. doi: 10.3791/51114.

21.

Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones.

Point V, Pavan Kumar KV, Marc S, Delorme V, Parsiegla G, Amara S, Carrière F, Buono G, Fotiadu F, Canaan S, Leclaire J, Cavalier JF.

Eur J Med Chem. 2012 Dec;58:452-63. doi: 10.1016/j.ejmech.2012.10.040. Epub 2012 Oct 29.

PMID:
23153815
22.

Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.

Point V, Malla RK, Diomande S, Martin BP, Delorme V, Carriere F, Canaan S, Rath NP, Spilling CD, Cavalier JF.

J Med Chem. 2012 Nov 26;55(22):10204-19. doi: 10.1021/jm301216x. Epub 2012 Nov 7.

23.

MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth.

Delorme V, Diomandé SV, Dedieu L, Cavalier JF, Carrière F, Kremer L, Leclaire J, Fotiadu F, Canaan S.

PLoS One. 2012;7(9):e46493. doi: 10.1371/journal.pone.0046493. Epub 2012 Sep 28.

24.

Inhibition of phospholipase A1, lipase and galactolipase activities of pancreatic lipase-related protein 2 by methyl arachidonyl fluorophosphonate (MAFP).

Amara S, Delorme V, Record M, Carrière F.

Biochim Biophys Acta. 2012 Nov;1821(11):1379-85. doi: 10.1016/j.bbalip.2012.07.014. Epub 2012 Jul 24.

PMID:
22835523
25.

The Arabidopsis peptide kiss of death is an inducer of programmed cell death.

Blanvillain R, Young B, Cai YM, Hecht V, Varoquaux F, Delorme V, Lancelin JM, Delseny M, Gallois P.

EMBO J. 2011 Mar 16;30(6):1173-83. doi: 10.1038/emboj.2011.14. Epub 2011 Feb 15.

26.

Effects of surfactants on lipase structure, activity, and inhibition.

Delorme V, Dhouib R, Canaan S, Fotiadu F, Carrière F, Cavalier JF.

Pharm Res. 2011 Aug;28(8):1831-42. doi: 10.1007/s11095-010-0362-9. Epub 2011 Jan 14. Review.

PMID:
21234659
27.

[Tetragametic chimerism: Case report].

Loriaux A, Boulet S, Delorme V, Althuser M, Giroud Lathuile C, Grego S, Amblard F, Dupuis C, Schaal JP, Jouk PS.

J Gynecol Obstet Biol Reprod (Paris). 2011 Feb;40(1):77-80. doi: 10.1016/j.jgyn.2010.06.011. Epub 2010 Aug 7. French.

28.

[Preterm births circumstances in babies born before 35 weeks in French Alpes: PREMALP study].

Delorme V, Bal G, Equy V, David-Tchouda S, Arnould P, Abraham L, Cans C, Debillon T.

J Gynecol Obstet Biol Reprod (Paris). 2010 Sep;39(5):387-94. doi: 10.1016/j.jgyn.2010.04.008. Epub 2010 Jun 9. French.

29.

ATR3 encodes a diflavin reductase essential for Arabidopsis embryo development.

Varadarajan J, Guilleminot J, Saint-Jore-Dupas C, Piégu B, Chabouté ME, Gomord V, Coolbaugh RC, Devic M, Delorme V.

New Phytol. 2010 Jul;187(1):67-82. doi: 10.1111/j.1469-8137.2010.03254.x. Epub 2010 Apr 12.

30.

CO2 binding by dynamic combinatorial chemistry: an environmental selection.

Leclaire J, Husson G, Devaux N, Delorme V, Charles L, Ziarelli F, Desbois P, Chaumonnot A, Jacquin M, Fotiadu F, Buono G.

J Am Chem Soc. 2010 Mar 17;132(10):3582-93. doi: 10.1021/ja909975q.

PMID:
20170120
31.

Two cutinase-like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function.

Schué M, Maurin D, Dhouib R, Bakala N'Goma JC, Delorme V, Lambeau G, Carrière F, Canaan S.

FASEB J. 2010 Jun;24(6):1893-903. doi: 10.1096/fj.09-144766. Epub 2010 Jan 26.

PMID:
20103719
32.

Identification of protein factors and U3 snoRNAs from a Brassica oleracea RNP complex involved in the processing of pre-rRNA.

Samaha H, Delorme V, Pontvianne F, Cooke R, Delalande F, Van Dorsselaer A, Echeverria M, Sáez-Vásquez J.

Plant J. 2010 Feb 1;61(3):383-98. doi: 10.1111/j.1365-313X.2009.04061.x. Epub 2009 Nov 3.

33.

A Toxoplasma type 2C serine-threonine phosphatase is involved in parasite growth in the mammalian host cell.

Jan G, Delorme V, Saksouk N, Abrivard M, Gonzalez V, Cayla X, Hakimi MA, Tardieux I.

Microbes Infect. 2009 Oct;11(12):935-45. doi: 10.1016/j.micinf.2009.06.002. Epub 2009 Jun 27.

PMID:
19563907
34.

Host cell entry by apicomplexa parasites requires actin polymerization in the host cell.

Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, Leroy C, Blazquez S, Ménard R, Tardieux I.

Cell Host Microbe. 2009 Mar 19;5(3):259-72. doi: 10.1016/j.chom.2009.01.011.

35.

The first zygotic division in Arabidopsis requires de novo transcription of thymidylate kinase.

Ronceret A, Gadea-Vacas J, Guilleminot J, Lincker F, Delorme V, Lahmy S, Pelletier G, Chabouté ME, Devic M.

Plant J. 2008 Mar;53(5):776-89. Epub 2007 Nov 23.

36.

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.

Delorme V, Machacek M, DerMardirossian C, Anderson KL, Wittmann T, Hanein D, Waterman-Storer C, Danuser G, Bokoch GM.

Dev Cell. 2007 Nov;13(5):646-62.

37.

The toxofilin-actin-PP2C complex of Toxoplasma: identification of interacting domains.

Jan G, Delorme V, David V, Revenu C, Rebollo A, Cayla X, Tardieux I.

Biochem J. 2007 Feb 1;401(3):711-9.

38.

Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis.

Ronceret A, Guilleminot J, Lincker F, Gadea-Vacas J, Delorme V, Bechtold N, Pelletier G, Delseny M, Chabouté ME, Devic M.

Plant J. 2005 Oct;44(2):223-36.

39.

The Arabidopsis root transcriptome by serial analysis of gene expression. Gene identification using the genome sequence.

Fizames C, Muños S, Cazettes C, Nacry P, Boucherez J, Gaymard F, Piquemal D, Delorme V, Commes T, Doumas P, Cooke R, Marti J, Sentenac H, Gojon A.

Plant Physiol. 2004 Jan;134(1):67-80.

40.

Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin.

Delorme V, Cayla X, Faure G, Garcia A, Tardieux I.

Mol Biol Cell. 2003 May;14(5):1900-12. Epub 2003 Feb 6.

41.

A role for Toxoplasma gondii type 1 ser/thr protein phosphatase in host cell invasion.

Delorme V, Garcia A, Cayla X, Tardieux I.

Microbes Infect. 2002 Mar;4(3):271-8.

PMID:
11909736
42.

Molecular diagnosis of recurrent Streptococcus mutans endocarditis by PCR amplification and sequencing.

Gauduchon V, Benito Y, Célard M, Mouren C, Delorme V, Philippe-Bert J, Etienne J, Vandenesch F.

Clin Microbiol Infect. 2001 Jan;7(1):36-7. No abstract available.

43.
44.

The S15 self-incompatibility haplotype in Brassica oleracea includes three S gene family members expressed in stigmas.

Cabrillac D, Delorme V, Garin J, Ruffio-Châble V, Giranton JL, Dumas C, Gaude T, Cock JM.

Plant Cell. 1999 May;11(5):971-86.

45.

A functional S locus anther gene is not required for the self-incompatibility response in Brassica oleracea.

Pastuglia M, Ruffio-Châble V, Delorme V, Gaude T, Dumas C, Cock JM.

Plant Cell. 1997 Nov;9(11):2065-76.

46.

Distribution of the synergistic haemolysin genes hld and slush with respect to agr in human staphylococci.

Donvito B, Etienne J, Greenland T, Mouren C, Delorme V, Vandenesch F.

FEMS Microbiol Lett. 1997 Jun 15;151(2):139-44.

47.

Staphylococcus pasteuri-specific oligonucleotide probes derived from a random amplified DNA fragment.

Vandenesch F, Perrier-Gros-Claude JD, Bes M, Fuhrmann C, Delorme V, Mouren C, Etienne J.

FEMS Microbiol Lett. 1995 Oct 1;132(1-2):147-52.

PMID:
7590156
48.

SLR3: a modified receptor kinase gene that has been adapted to encode a putative secreted glycoprotein similar to the S locus glycoprotein.

Cock JM, Stanchev B, Delorme V, Croy RR, Dumas C.

Mol Gen Genet. 1995 Jul 28;248(2):151-61.

PMID:
7651338
49.

Characterization of the S locus genes, SLG and SRK, of the Brassica S3 haplotype: identification of a membrane-localized protein encoded by the S locus receptor kinase gene.

Delorme V, Giranton JL, Hatzfeld Y, Friry A, Heizmann P, Ariza MJ, Dumas C, Gaude T, Cock JM.

Plant J. 1995 Mar;7(3):429-40.

50.

Characterization of clinically significant isolates of Staphylococcus epidermidis from patients with endocarditis.

Etienne J, Brun Y, el Solh N, Delorme V, Mouren C, Bes M, Fleurette J.

J Clin Microbiol. 1988 Apr;26(4):613-7.

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