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Items: 15

1.

PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry.

Palmigiano A, Santaniello F, Cerutti A, Penkov D, Purushothaman D, Makhija E, Luzi L, di Fagagna FD, Pelicci PG, Shivashankar V, Dellino GI, Blasi F.

Sci Rep. 2018 Feb 16;8(1):3198. doi: 10.1038/s41598-018-21363-4.

2.

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

Carugo A, Genovese G, Seth S, Nezi L, Rose JL, Bossi D, Cicalese A, Shah PK, Viale A, Pettazzoni PF, Akdemir KC, Bristow CA, Robinson FS, Tepper J, Sanchez N, Gupta S, Estecio MR, Giuliani V, Dellino GI, Riva L, Yao W, Di Francesco ME, Green T, D'Alesio C, Corti D, Kang Y, Jones P, Wang H, Fleming JB, Maitra A, Pelicci PG, Chin L, DePinho RA, Lanfrancone L, Heffernan TP, Draetta GF.

Cell Rep. 2016 Jun 28;16(1):133-147. doi: 10.1016/j.celrep.2016.05.063. Epub 2016 Jun 16.

3.

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L.

Cancer Discov. 2016 Jun;6(6):650-63. doi: 10.1158/2159-8290.CD-15-1200. Epub 2016 May 13.

4.

Cell cycle-dependent resolution of DNA double-strand breaks.

Ambrosio S, Di Palo G, Napolitano G, Amente S, Dellino GI, Faretta M, Pelicci PG, Lania L, Majello B.

Oncotarget. 2016 Jan 26;7(4):4949-60. doi: 10.18632/oncotarget.6644.

5.

Peak shape clustering reveals biological insights.

Cremona MA, Sangalli LM, Vantini S, Dellino GI, Pelicci PG, Secchi P, Riva L.

BMC Bioinformatics. 2015 Oct 28;16:349. doi: 10.1186/s12859-015-0787-6.

6.

Next-generation sequencing and DNA replication in human cells: the future has arrived.

Dellino GI, Pelicci PG.

Future Oncol. 2014 Mar;10(4):683-93. doi: 10.2217/fon.13.182. Review.

PMID:
24754597
7.

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.

Riva L, Ronchini C, Bodini M, Lo-Coco F, Lavorgna S, Ottone T, Martinelli G, Iacobucci I, Tarella C, Cignetti A, Volorio S, Bernard L, Russo A, Melloni GE, Luzi L, Alcalay M, Dellino GI, Pelicci PG.

Blood Cancer J. 2014 Mar 21;4:e195. doi: 10.1038/bcj.2014.19. No abstract available.

8.

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.

Riva L, Ronchini C, Bodini M, Lo-Coco F, Lavorgna S, Ottone T, Martinelli G, Iacobucci I, Tarella C, Cignetti A, Volorio S, Bernard L, Russo A, Melloni GE, Luzi L, Alcalay M, Dellino GI, Pelicci PG.

Blood Cancer J. 2013 Sep 13;3:e147. doi: 10.1038/bcj.2013.46. No abstract available.

9.

Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation.

Napolitano G, Amente S, Lavadera ML, Di Palo G, Ambrosio S, Lania L, Dellino GI, Pelicci PG, Majello B.

Mutat Res. 2013 Sep;749(1-2):21-7. doi: 10.1016/j.mrfmmm.2013.07.005. Epub 2013 Jul 29.

10.

Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing.

Dellino GI, Cittaro D, Piccioni R, Luzi L, Banfi S, Segalla S, Cesaroni M, Mendoza-Maldonado R, Giacca M, Pelicci PG.

Genome Res. 2013 Jan;23(1):1-11. doi: 10.1101/gr.142331.112. Epub 2012 Nov 27.

11.

Pathology tissue-chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples.

Fanelli M, Amatori S, Barozzi I, Soncini M, Dal Zuffo R, Bucci G, Capra M, Quarto M, Dellino GI, Mercurio C, Alcalay M, Viale G, Pelicci PG, Minucci S.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21535-40. doi: 10.1073/pnas.1007647107. Epub 2010 Nov 24.

12.

Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene.

Kahn TG, Schwartz YB, Dellino GI, Pirrotta V.

J Biol Chem. 2006 Sep 29;281(39):29064-75. Epub 2006 Aug 2.

13.

Polycomb silencing mechanisms in Drosophila.

Schwartz YB, Kahn TG, Dellino GI, Pirrotta V.

Cold Spring Harb Symp Quant Biol. 2004;69:301-8. No abstract available.

PMID:
16117662
14.

Polycomb silencing blocks transcription initiation.

Dellino GI, Schwartz YB, Farkas G, McCabe D, Elgin SC, Pirrotta V.

Mol Cell. 2004 Mar 26;13(6):887-93.

15.

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