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Items: 45


Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation.

Della Chiesa M, De Maria A, Muccio L, Bozzano F, Sivori S, Moretta L.

Front Microbiol. 2019 Oct 4;10:2297. doi: 10.3389/fmicb.2019.02297. eCollection 2019. Review.


NK Cell-Based Immunotherapy for Hematological Malignancies.

Sivori S, Meazza R, Quintarelli C, Carlomagno S, Della Chiesa M, Falco M, Moretta L, Locatelli F, Pende D.

J Clin Med. 2019 Oct 16;8(10). pii: E1702. doi: 10.3390/jcm8101702. Review.


Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis.

Pesce S, Belgrano V, Greppi M, Carlomagno S, Squillario M, Barla A, Della Chiesa M, Di Domenico S, Mavilio D, Moretta L, Candiani S, Sivori S, De Cian F, Marcenaro E.

Front Immunol. 2019 Aug 21;10:1963. doi: 10.3389/fimmu.2019.01963. eCollection 2019.


An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More.

Vitale M, Cantoni C, Della Chiesa M, Ferlazzo G, Carlomagno S, Pende D, Falco M, Pessino A, Muccio L, De Maria A, Marcenaro E, Moretta L, Sivori S.

Front Immunol. 2019 Jun 19;10:1415. doi: 10.3389/fimmu.2019.01415. eCollection 2019. Review.


Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content.

Bono M, Pende D, Bertaina A, Moretta A, Della Chiesa M, Sivori S, Zecca M, Locatelli F, Moretta L, Bottino C, Falco M.

J Immunol. 2018 Sep 1;201(5):1460-1467. doi: 10.4049/jimmunol.1800564. Epub 2018 Aug 1.


Late Development of FcεRγneg Adaptive Natural Killer Cells Upon Human Cytomegalovirus Reactivation in Umbilical Cord Blood Transplantation Recipients.

Muccio L, Falco M, Bertaina A, Locatelli F, Frassoni F, Sivori S, Moretta L, Moretta A, Della Chiesa M.

Front Immunol. 2018 May 15;9:1050. doi: 10.3389/fimmu.2018.01050. eCollection 2018.


NK Cells Mediate a Crucial Graft-versus-Leukemia Effect in Haploidentical-HSCT to Cure High-Risk Acute Leukemia.

Locatelli F, Pende D, Falco M, Della Chiesa M, Moretta A, Moretta L.

Trends Immunol. 2018 Jul;39(7):577-590. doi: 10.1016/ Epub 2018 May 21. Review.


Markers and function of human NK cells in normal and pathological conditions.

Del Zotto G, Marcenaro E, Vacca P, Sivori S, Pende D, Della Chiesa M, Moretta F, Ingegnere T, Mingari MC, Moretta A, Moretta L.

Cytometry B Clin Cytom. 2017 Mar;92(2):100-114. doi: 10.1002/cyto.b.21508. Epub 2017 Feb 12. Review.


Features of Memory-Like and PD-1(+) Human NK Cell Subsets.

Della Chiesa M, Pesce S, Muccio L, Carlomagno S, Sivori S, Moretta A, Marcenaro E.

Front Immunol. 2016 Sep 14;7:351. doi: 10.3389/fimmu.2016.00351. eCollection 2016. Review.


PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance.

Dondero A, Pastorino F, Della Chiesa M, Corrias MV, Morandi F, Pistoia V, Olive D, Bellora F, Locatelli F, Castellano A, Moretta L, Moretta A, Bottino C, Castriconi R.

Oncoimmunology. 2015 Jul 15;5(1):e1064578. eCollection 2016.


Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies.

Muccio L, Bertaina A, Falco M, Pende D, Meazza R, Lopez-Botet M, Moretta L, Locatelli F, Moretta A, Della Chiesa M.

Haematologica. 2016 Mar;101(3):371-81. doi: 10.3324/haematol.2015.134155. Epub 2015 Dec 11.


Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?

Della Chiesa M, Sivori S, Carlomagno S, Moretta L, Moretta A.

Front Immunol. 2015 Nov 9;6:573. doi: 10.3389/fimmu.2015.00573. eCollection 2015. Review.


Haploidentical Haematopoietic Stem Cell Transplantation: Role of NK Cells and Effect of Cytomegalovirus Infections.

Della Chiesa M, Moretta L, Muccio L, Bertaina A, Moretta F, Locatelli F, Moretta A.

Curr Top Microbiol Immunol. 2016;395:209-24. doi: 10.1007/82_2015_450. Review.


TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses.

Riise RE, Bernson E, Aurelius J, Martner A, Pesce S, Della Chiesa M, Marcenaro E, Bylund J, Hellstrand K, Moretta L, Moretta A, Thorén FB.

J Immunol. 2015 Aug 1;195(3):1121-8. doi: 10.4049/jimmunol.1500709. Epub 2015 Jun 17.


Human NK cell response to pathogens.

Della Chiesa M, Marcenaro E, Sivori S, Carlomagno S, Pesce S, Moretta A.

Semin Immunol. 2014 Apr;26(2):152-60. doi: 10.1016/j.smim.2014.02.001. Epub 2014 Feb 28. Review.


Human cytomegalovirus infection promotes rapid maturation of NK cells expressing activating killer Ig-like receptor in patients transplanted with NKG2C-/- umbilical cord blood.

Della Chiesa M, Falco M, Bertaina A, Muccio L, Alicata C, Frassoni F, Locatelli F, Moretta L, Moretta A.

J Immunol. 2014 Feb 15;192(4):1471-9. doi: 10.4049/jimmunol.1302053. Epub 2014 Jan 17.


Impact of HCMV Infection on NK Cell Development and Function after HSCT.

Della Chiesa M, Falco M, Muccio L, Bertaina A, Locatelli F, Moretta A.

Front Immunol. 2013 Dec 13;4:458. doi: 10.3389/fimmu.2013.00458. Review.


CMV induces rapid NK cell maturation in HSCT recipients.

Della Chiesa M, Muccio L, Moretta A.

Immunol Lett. 2013 Sep-Oct;155(1-2):11-3. doi: 10.1016/j.imlet.2013.09.020. Epub 2013 Sep 26. Review.


Human NK cell receptors/markers: a tool to analyze NK cell development, subsets and function.

Montaldo E, Del Zotto G, Della Chiesa M, Mingari MC, Moretta A, De Maria A, Moretta L.

Cytometry A. 2013 Aug;83(8):702-13. doi: 10.1002/cyto.a.22302. Epub 2013 May 6. Review.


Human NK Cells induce neutrophil apoptosis via an NKp46- and Fas-dependent mechanism.

Thorén FB, Riise RE, Ousbäck J, Della Chiesa M, Alsterholm M, Marcenaro E, Pesce S, Prato C, Cantoni C, Bylund J, Moretta L, Moretta A.

J Immunol. 2012 Feb 15;188(4):1668-74. doi: 10.4049/jimmunol.1102002. Epub 2012 Jan 9.


Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus?

Della Chiesa M, Falco M, Podestà M, Locatelli F, Moretta L, Frassoni F, Moretta A.

Blood. 2012 Jan 12;119(2):399-410. doi: 10.1182/blood-2011-08-372003. Epub 2011 Nov 17.


NK cells and their receptors during viral infections.

Marcenaro E, Carlomagno S, Pesce S, Della Chiesa M, Parolini S, Moretta A, Sivori S.

Immunotherapy. 2011 Sep;3(9):1075-86. doi: 10.2217/imt.11.99. Review.


Role of alloreactive KIR2DS1(+) NK cells in haploidentical hematopoietic stem cell transplantation.

Marcenaro E, Carlomagno S, Pesce S, Della Chiesa M, Moretta A, Sivori S.

J Leukoc Biol. 2011 Oct;90(4):661-7. doi: 10.1189/jlb.0311137. Epub 2011 Jul 26. Review.


GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues.

Della Chiesa M, Falco M, Parolini S, Bellora F, Petretto A, Romeo E, Balsamo M, Gambarotti M, Scordamaglia F, Tabellini G, Facchetti F, Vermi W, Bottino C, Moretta A, Vitale M.

Int Immunol. 2010 Feb;22(2):91-100. doi: 10.1093/intimm/dxp116. Epub 2009 Dec 14.


Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells.

Romagné F, André P, Spee P, Zahn S, Anfossi N, Gauthier L, Capanni M, Ruggeri L, Benson DM Jr, Blaser BW, Della Chiesa M, Moretta A, Vivier E, Caligiuri MA, Velardi A, Wagtmann N.

Blood. 2009 Sep 24;114(13):2667-77. doi: 10.1182/blood-2009-02-206532. Epub 2009 Jun 24.


The NK/DC complot.

Marcenaro E, Della Chiesa M, Pesce S, Agaugué S, Moretta A.

Adv Exp Med Biol. 2009;633:7-16. Review. No abstract available.


Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.

Della Chiesa M, Romeo E, Falco M, Balsamo M, Augugliaro R, Moretta L, Bottino C, Moretta A, Vitale M.

Eur J Immunol. 2008 Aug;38(8):2284-9. doi: 10.1002/eji.200838434.


In the thick of the fray: NK cells in inflamed tissues.

Marcenaro E, Della Chiesa M, Ferranti B, Moretta A.

Adv Exp Med Biol. 2007;598:12-9. Review. No abstract available.


Functional characterization of natural killer cells in type I leukocyte adhesion deficiency.

Castriconi R, Dondero A, Cantoni C, Della Chiesa M, Prato C, Nanni M, Fiorini M, Notarangelo L, Parolini S, Moretta L, Notarangelo L, Moretta A, Bottino C.

Blood. 2007 Jun 1;109(11):4873-81. Epub 2007 Feb 1.


It's only innate immunity but I like it.

Marcenaro E, Della Chiesa M, Dondero A, Ferranti B, Moretta A.

Adv Exp Med Biol. 2007;590:89-101. Review. No abstract available.


The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function.

Della Chiesa M, Carlomagno S, Frumento G, Balsamo M, Cantoni C, Conte R, Moretta L, Moretta A, Vitale M.

Blood. 2006 Dec 15;108(13):4118-25. Epub 2006 Aug 10.


Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses.

Della Chiesa M, Romagnani C, Thiel A, Moretta L, Moretta A.

Blood. 2006 Dec 1;108(12):3851-8. Epub 2006 Jul 27.


Early liaisons between cells of the innate immune system in inflamed peripheral tissues.

Moretta A, Marcenaro E, Sivori S, Della Chiesa M, Vitale M, Moretta L.

Trends Immunol. 2005 Dec;26(12):668-75. Epub 2005 Sep 28. Review.


Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells.

Romagnani C, Della Chiesa M, Kohler S, Moewes B, Radbruch A, Moretta L, Moretta A, Thiel A.

Eur J Immunol. 2005 Aug;35(8):2452-8.


NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.

Vitale M, Della Chiesa M, Carlomagno S, Pende D, Aricò M, Moretta L, Moretta A.

Blood. 2005 Jul 15;106(2):566-71. Epub 2005 Mar 22.


IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors.

Marcenaro E, Della Chiesa M, Bellora F, Parolini S, Millo R, Moretta L, Moretta A.

J Immunol. 2005 Apr 1;174(7):3992-8.


Pathogen-induced private conversations between natural killer and dendritic cells.

Della Chiesa M, Sivori S, Castriconi R, Marcenaro E, Moretta A.

Trends Microbiol. 2005 Mar;13(3):128-36. Review.


Shaping of adaptive immunity by innate interactions.

Castriconi R, Della Chiesa M, Moretta A.

C R Biol. 2004 Jun;327(6):533-7. Review.


Isolation of a novel KIR2DL3-specific mAb: comparative analysis of the surface distribution and function of KIR2DL2, KIR2DL3 and KIR2DS2.

Vitale M, Carlomagno S, Falco M, Pende D, Romeo E, Rivera P, Della Chiesa M, Mavilio D, Moretta A.

Int Immunol. 2004 Oct;16(10):1459-66. Epub 2004 Aug 16.


CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells.

Sivori S, Falco M, Della Chiesa M, Carlomagno S, Vitale M, Moretta L, Moretta A.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10116-21. Epub 2004 Jun 24.


The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors.

Della Chiesa M, Vitale M, Carlomagno S, Ferlazzo G, Moretta L, Moretta A.

Eur J Immunol. 2003 Jun;33(6):1657-66. Erratum in: Eur J Immunol. 2003 Oct;33(10):2947.


Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.

Zambello R, Falco M, Della Chiesa M, Trentin L, Carollo D, Castriconi R, Cannas G, Carlomagno S, Cabrelle A, Lamy T, Agostini C, Moretta A, Semenzato G, Vitale M.

Blood. 2003 Sep 1;102(5):1797-805. Epub 2003 May 15.


Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells.

Castriconi R, Cantoni C, Della Chiesa M, Vitale M, Marcenaro E, Conte R, Biassoni R, Bottino C, Moretta L, Moretta A.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4120-5. Epub 2003 Mar 19.


Natural killer lymphocytes: "null cells" no more.

Moretta A, Bottino C, Sivori S, Marcenaro E, Castriconi R, Della Chiesa M, Carlomagno S, Augugliaro R, Nanni M, Vitale M, Millo R.

Ital J Anat Embryol. 2001 Oct-Dec;106(4):335-42. Review.


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