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Discovery of O-Linked Carbohydrate on HIV-1 Envelope and Its Role in Shielding against One Category of Broadly Neutralizing Antibodies.

Silver ZA, Antonopoulos A, Haslam SM, Dell A, Dickinson GM, Seaman MS, Desrosiers RC.

Cell Rep. 2020 Feb 11;30(6):1862-1869.e4. doi: 10.1016/j.celrep.2020.01.056.


Insights into the hyperglycosylation of human chorionic gonadotropin revealed by glycomics analysis.

Ibeto L, Antonopoulos A, Grassi P, Pang PC, Panico M, Bobdiwala S, Al-Memar M, Davis P, Davis M, Norman Taylor J, Almeida P, Johnson MR, Harvey R, Bourne T, Seckl M, Clark G, Haslam SM, Dell A.

PLoS One. 2020 Feb 11;15(2):e0228507. doi: 10.1371/journal.pone.0228507. eCollection 2020.


Choice of Host Cell Line Is Essential for the Functional Glycosylation of the Fc Region of Human IgG1 Inhibitors of Influenza B Viruses.

Blundell PA, Lu D, Dell A, Haslam S, Pleass RJ.

J Immunol. 2020 Feb 15;204(4):1022-1034. doi: 10.4049/jimmunol.1901145. Epub 2020 Jan 6.


Glycan biomarkers for Alzheimer disease correlate with T-tau and P-tau in cerebrospinal fluid in subjective cognitive impairment.

Schedin-Weiss S, Gaunitz S, Sui P, Chen Q, Haslam SM, Blennow K, Winblad B, Dell A, Tjernberg LO.

FEBS J. 2019 Dec 30. doi: 10.1111/febs.15197. [Epub ahead of print]


East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide.

Li H, Marceau M, Yang T, Liao T, Tang X, Hu R, Xie Y, Tang H, Tay A, Shi Y, Shen Y, Yang T, Pi X, Lamichhane B, Luo Y, Debowski AW, Nilsson HO, Haslam SM, Mulloy B, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

PLoS Genet. 2019 Nov 20;15(11):e1008497. doi: 10.1371/journal.pgen.1008497. eCollection 2019 Nov.


Resource distribution and internal factors interact to govern movement of a freshwater snail.

Cloyed CS, Dell AI.

Proc Biol Sci. 2019 Sep 25;286(1911):20191610. doi: 10.1098/rspb.2019.1610. Epub 2019 Sep 25.


Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae.

North SJ, Botchway K, Doonan J, Lumb FE, Dell A, Harnett W, Haslam SM.

Glycobiology. 2019 Jul 19;29(8):562-571. doi: 10.1093/glycob/cwz035.


Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen.

Abouelhadid S, North SJ, Hitchen P, Vohra P, Chintoan-Uta C, Stevens M, Dell A, Cuccui J, Wren BW.

mBio. 2019 Apr 23;10(2). pii: e00297-19. doi: 10.1128/mBio.00297-19.


Different metrics of thermal acclimation yield similar effects of latitude, acclimation duration, and body mass on acclimation capacities.

Rohr JR, Civitello DJ, Cohen JM, Roznik EA, Sinervo B, Dell AI.

Glob Chang Biol. 2019 Jul;25(7):e3-e4. doi: 10.1111/gcb.14653. Epub 2019 May 6. No abstract available.


Long-term exposure to higher temperature increases the thermal sensitivity of grazer metabolism and movement.

Cloyed CS, Dell AI, Hayes T, Kordas RL, O'Gorman EJ.

J Anim Ecol. 2019 Jun;88(6):833-844. doi: 10.1111/1365-2656.12976. Epub 2019 Apr 1.


Serum IgA1 shows increased levels of α2,6-linked sialic acid in breast cancer.

Lomax-Browne HJ, Robertson C, Antonopoulos A, Leathem AJC, Haslam SM, Dell A, Dwek MV.

Interface Focus. 2019 Apr 6;9(2):20180079. doi: 10.1098/rsfs.2018.0079. Epub 2019 Feb 15.


Insertion of N-Terminal Hinge Glycosylation Enhances Interactions of the Fc Region of Human IgG1 Monomers with Glycan-Dependent Receptors and Blocks Hemagglutination by the Influenza Virus.

Blundell PA, Lu D, Wilkinson M, Dell A, Haslam S, Pleass RJ.

J Immunol. 2019 Mar 1;202(5):1595-1611. doi: 10.4049/jimmunol.1801337. Epub 2019 Jan 25.


Metabolic asymmetry and the global diversity of marine predators.

Grady JM, Maitner BS, Winter AS, Kaschner K, Tittensor DP, Record S, Smith FA, Wilson AM, Dell AI, Zarnetske PL, Wearing HJ, Alfaro B, Brown JH.

Science. 2019 Jan 25;363(6425). pii: eaat4220. doi: 10.1126/science.aat4220. Epub 2019 Jan 24.


Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans.

Giovannone N, Antonopoulos A, Liang J, Geddes Sweeney J, Kudelka MR, King SL, Lee GS, Cummings RD, Dell A, Barthel SR, Widlund HR, Haslam SM, Dimitroff CJ.

Front Immunol. 2018 Dec 14;9:2857. doi: 10.3389/fimmu.2018.02857. eCollection 2018.


Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Cell Chem Biol. 2018 Dec 20;25(12):1519-1532.e5. doi: 10.1016/j.chembiol.2018.09.012. Epub 2018 Oct 18.


The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants.

El Jellas K, Johansson BB, Fjeld K, Antonopoulos A, Immervoll H, Choi MH, Hoem D, Lowe ME, Lombardo D, Njølstad PR, Dell A, Mas E, Haslam SM, Molven A.

J Biol Chem. 2018 Dec 14;293(50):19476-19491. doi: 10.1074/jbc.RA118.001934. Epub 2018 Oct 12.


XBP1s activation can globally remodel N-glycan structure distribution patterns.

Wong MY, Chen K, Antonopoulos A, Kasper BT, Dewal MB, Taylor RJ, Whittaker CA, Hein PP, Dell A, Genereux JC, Haslam SM, Mahal LK, Shoulders MD.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10089-E10098. doi: 10.1073/pnas.1805425115. Epub 2018 Oct 10.


The S-layer protein of a Clostridium difficile SLCT-11 strain displays a complex glycan required for normal cell growth and morphology.

Richards E, Bouché L, Panico M, Arbeloa A, Vinogradov E, Morris H, Wren B, Logan SM, Dell A, Fairweather NF.

J Biol Chem. 2018 Nov 23;293(47):18123-18137. doi: 10.1074/jbc.RA118.004530. Epub 2018 Oct 1.


Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.

Sweeney JG, Liang J, Antonopoulos A, Giovannone N, Kang S, Mondala TS, Head SR, King SL, Tani Y, Brackett D, Dell A, Murphy GF, Haslam SM, Widlund HR, Dimitroff CJ.

Nat Commun. 2018 Aug 22;9(1):3368. doi: 10.1038/s41467-018-05795-0.


Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans.

Giovannone N, Liang J, Antonopoulos A, Geddes Sweeney J, King SL, Pochebit SM, Bhattacharyya N, Lee GS, Dell A, Widlund HR, Haslam SM, Dimitroff CJ.

Nat Commun. 2018 Aug 17;9(1):3287. doi: 10.1038/s41467-018-05770-9.


Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation.

Veerapen N, Kharkwal SS, Jervis P, Bhowruth V, Besra AK, North SJ, Haslam SM, Dell A, Hobrath J, Quaid PJ, Moynihan PJ, Cox LR, Kharkwal H, Zauderer M, Besra GS, Porcelli SA.

Bioconjug Chem. 2018 Sep 19;29(9):3161-3173. doi: 10.1021/acs.bioconjchem.8b00484. Epub 2018 Aug 23.


The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis.

Jankute M, Alderwick LJ, Moorey AR, Joe M, Gurcha SS, Eggeling L, Lowary TL, Dell A, Pang PC, Yang T, Haslam S, Besra GS.

Cell Surf. 2018 Jun;2:38-53. doi: 10.1016/j.tcsw.2018.06.003.


The complex drivers of thermal acclimation and breadth in ectotherms.

Rohr JR, Civitello DJ, Cohen JM, Roznik EA, Sinervo B, Dell AI.

Ecol Lett. 2018 Sep;21(9):1425-1439. doi: 10.1111/ele.13107. Epub 2018 Jul 16. Review.


Orthopaedic Surgeon Density in South Africa.

Dell AJ, Gray S, Fraser R, Held M, Dunn R.

World J Surg. 2018 Dec;42(12):3849-3855. doi: 10.1007/s00268-018-4709-4.


Towards automation of glycomic profiling of complex biological materials.

Shubhakar A, Pang PC, Fernandes DL, Dell A, Spencer DIR, Haslam SM.

Glycoconj J. 2018 Jun;35(3):311-321. doi: 10.1007/s10719-018-9825-8. Epub 2018 Jun 16.


Where are general surgeons located in South Africa?

Dell AJ, Kahn D.

S Afr J Surg. 2018 Mar;56(1):12-18.


Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesion.

Zhu F, Zhang H, Yang T, Haslam SM, Dell A, Wu H.

J Biol Chem. 2018 Mar 30;293(13):4952. doi: 10.1074/jbc.AAC118.002681. No abstract available.


Collective animal navigation and migratory culture: from theoretical models to empirical evidence.

Berdahl AM, Kao AB, Flack A, Westley PAH, Codling EA, Couzin ID, Dell AI, Biro D.

Philos Trans R Soc Lond B Biol Sci. 2018 May 19;373(1746). pii: 20170009. doi: 10.1098/rstb.2017.0009. Review.


The thermal dependence of carbon stable isotope incorporation and trophic discrimination in the domestic cricket, Acheta domesticus.

Cloyed CS, Eason PK, Dell AI.

J Insect Physiol. 2018 May - Jun;107:34-40. doi: 10.1016/j.jinsphys.2018.02.003. Epub 2018 Feb 9.


Pediatric surgeon density in South Africa.

Dell A, Numanoglu A, Arnold M, Rode H.

J Pediatr Surg. 2018 Oct;53(10):2065-2071. doi: 10.1016/j.jpedsurg.2017.11.067. Epub 2017 Dec 27. Review.


Infections on the move: how transient phases of host movement influence disease spread.

Daversa DR, Fenton A, Dell AI, Garner TWJ, Manica A.

Proc Biol Sci. 2017 Dec 20;284(1869). pii: 20171807. doi: 10.1098/rspb.2017.1807. Review.


Geographical maldistribution of surgical resources in South Africa: A review of the number of hospitals, hospital beds and surgical beds.

Dell AJ, Kahn D.

S Afr Med J. 2017 Nov 27;107(12):1099-1105. doi: 10.7196/SAMJ.2017.v107i12.12539.


The little things that run: a general scaling of invertebrate exploratory speed with body mass.

Hirt MR, Lauermann T, Brose U, Noldus LPJJ, Dell AI.

Ecology. 2017 Nov;98(11):2751-2757. doi: 10.1002/ecy.2006.


Structural Analysis of Glycans.

Mulloy B, Dell A, Stanley P, H. Prestegard J.

In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Chapter 50.


Surgical Resources in South Africa: An International Comparison and Deficit Calculation.

Dell AJ, Kahn D.

World J Surg. 2018 Feb;42(2):541-548. doi: 10.1007/s00268-017-4176-3.


Human Immunodeficiency Virus and Simian Immunodeficiency Virus Maintain High Levels of Infectivity in the Complete Absence of Mucin-Type O-Glycosylation.

Termini JM, Church ES, Silver ZA, Haslam SM, Dell A, Desrosiers RC.

J Virol. 2017 Sep 12;91(19). pii: e01228-17. doi: 10.1128/JVI.01228-17. Print 2017 Oct 1.


Insights from the redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains.

Li H, Yang T, Liao T, Debowski AW, Nilsson HO, Haslam SM, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

Microb Cell. 2017 Apr 25;4(5):175-178. doi: 10.15698/mic2017.05.574.


HEK293T cell lines defective for O-linked glycosylation.

Termini JM, Silver ZA, Connor B, Antonopoulos A, Haslam SM, Dell A, Desrosiers RC.

PLoS One. 2017 Jun 27;12(6):e0179949. doi: 10.1371/journal.pone.0179949. eCollection 2017.


Managing consequences of climate-driven species redistribution requires integration of ecology, conservation and social science.

Bonebrake TC, Brown CJ, Bell JD, Blanchard JL, Chauvenet A, Champion C, Chen IC, Clark TD, Colwell RK, Danielsen F, Dell AI, Donelson JM, Evengård B, Ferrier S, Frusher S, Garcia RA, Griffis RB, Hobday AJ, Jarzyna MA, Lee E, Lenoir J, Linnetved H, Martin VY, McCormack PC, McDonald J, McDonald-Madden E, Mitchell N, Mustonen T, Pandolfi JM, Pettorelli N, Possingham H, Pulsifer P, Reynolds M, Scheffers BR, Sorte CJB, Strugnell JM, Tuanmu MN, Twiname S, Vergés A, Villanueva C, Wapstra E, Wernberg T, Pecl GT.

Biol Rev Camb Philos Soc. 2018 Feb;93(1):284-305. doi: 10.1111/brv.12344. Epub 2017 Jun 1. Review.


Effects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactions.

Pham ND, Pang PC, Krishnamurthy S, Wands AM, Grassi P, Dell A, Haslam SM, Kohler JJ.

J Biol Chem. 2017 Jun 9;292(23):9637-9651. doi: 10.1074/jbc.M116.764597. Epub 2017 Apr 19.


The redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains.

Li H, Yang T, Liao T, Debowski AW, Nilsson HO, Fulurija A, Haslam SM, Mulloy B, Dell A, Stubbs KA, Marshall BJ, Benghezal M.

PLoS Pathog. 2017 Mar 17;13(3):e1006280. doi: 10.1371/journal.ppat.1006280. eCollection 2017 Mar.


Incidence and management of postoperative bile leaks: A prospective cohort analysis of 467 liver resections.

Dell AJ, Krige JE, Jonas E, Thomson SR, Beningfield SJ, Kotze UK, Tromp SA, Burmeister S, Bernon MM, Bornman PC.

S Afr J Surg. 2016 Sep;54(3):18-22.


Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.

Choo M, Tan HL, Ding V, Castangia R, Belgacem O, Liau B, Hartley-Tassell L, Haslam SM, Dell A, Choo A.

J Biol Chem. 2017 Apr 14;292(15):6163-6176. doi: 10.1074/jbc.M116.768887. Epub 2017 Feb 6.


Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib.

Letkemann R, Wittkowski H, Antonopoulos A, Podskabi T, Haslam SM, Föll D, Dell A, Marquardt T.

Int Immunopharmacol. 2017 Mar;44:216-225. doi: 10.1016/j.intimp.2017.01.020. Epub 2017 Jan 23.


Engineering and Dissecting the Glycosylation Pathway of a Streptococcal Serine-rich Repeat Adhesin.

Zhu F, Zhang H, Yang T, Haslam SM, Dell A, Wu H.

J Biol Chem. 2016 Dec 30;291(53):27354-27363. doi: 10.1074/jbc.M116.752998. Erratum in: J Biol Chem. 2018 Mar 30;293(13):4952.


The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.

Liu Y, McBride R, Stoll M, Palma AS, Silva L, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Novotny MV, Packer NH, Ranzinger R, Rapp E, Rudd PM, Struwe WB, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C, Paulson JC, Feizi T, Smith DF.

Glycobiology. 2017 Apr;27(4):280-284. Epub 2016 Nov 22.


The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans.

Bouché L, Panico M, Hitchen P, Binet D, Sastre F, Faulds-Pain A, Valiente E, Vinogradov E, Aubry A, Fulton K, Twine S, Logan SM, Wren BW, Dell A, Morris HR.

J Biol Chem. 2016 Dec 2;291(49):25439-25449. Epub 2016 Oct 7.


Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.

Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW.

J Biol Chem. 2016 Dec 2;291(49):25450-25461. Epub 2016 Oct 4.

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