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Items: 36

1.

RAGE is a Critical Mediator of Pulmonary Oxidative Stress, Alveolar Macrophage Activation and Emphysema in Response to Cigarette Smoke.

Sanders KA, Delker DA, Huecksteadt T, Beck E, Wuren T, Chen Y, Zhang Y, Hazel MW, Hoidal JR.

Sci Rep. 2019 Jan 18;9(1):231. doi: 10.1038/s41598-018-36163-z.

2.

Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2.

Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, Guinney J, Dienstmann R, Vilar E.

Ann Oncol. 2018 Oct 1;29(10):2061-2067. doi: 10.1093/annonc/mdy337.

PMID:
30412224
3.

Small RNA sequencing of sessile serrated polyps identifies microRNA profile associated with colon cancer.

Kanth P, Hazel MW, Boucher KM, Yang Z, Wang L, Bronner MP, Boylan KE, Burt RW, Westover M, Neklason DW, Delker DA.

Genes Chromosomes Cancer. 2019 Jan;58(1):23-33. doi: 10.1002/gcc.22686. Epub 2018 Nov 18.

PMID:
30265426
4.

RNA sequencing confirms similarities between PPI-responsive oesophageal eosinophilia and eosinophilic oesophagitis.

Peterson KA, Yoshigi M, Hazel MW, Delker DA, Lin E, Krishnamurthy C, Consiglio N, Robson J, Yandell M, Clayton F.

Aliment Pharmacol Ther. 2018 Jul;48(2):219-225. doi: 10.1111/apt.14825. Epub 2018 Jun 4.

PMID:
29863285
5.

Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia.

Delker DA, Wood AC, Snow AK, Samadder NJ, Samowitz WS, Affolter KE, Boucher KM, Pappas LM, Stijleman IJ, Kanth P, Byrne KR, Burt RW, Bernard PS, Neklason DW.

Cancer Prev Res (Phila). 2018 Jan;11(1):4-15. doi: 10.1158/1940-6207.CAPR-17-0130. Epub 2017 Nov 6.

6.

Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.

Kanth P, Bronner MP, Boucher KM, Burt RW, Neklason DW, Hagedorn CH, Delker DA.

Cancer Prev Res (Phila). 2016 Jun;9(6):456-65. doi: 10.1158/1940-6207.CAPR-15-0363. Epub 2016 Mar 29.

7.

RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers.

Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH.

PLoS One. 2014 Feb 12;9(2):e88367. doi: 10.1371/journal.pone.0088367. eCollection 2014.

8.

The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.

McFarland AP, Horner SM, Jarret A, Joslyn RC, Bindewald E, Shapiro BA, Delker DA, Hagedorn CH, Carrington M, Gale M Jr, Savan R.

Nat Immunol. 2014 Jan;15(1):72-9. doi: 10.1038/ni.2758. Epub 2013 Nov 17.

9.

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease.

Smalling RL, Delker DA, Zhang Y, Nieto N, McGuiness MS, Liu S, Friedman SL, Hagedorn CH, Wang L.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G364-74. doi: 10.1152/ajpgi.00077.2013. Epub 2013 Jun 27.

10.

Association of brominated proteins and changes in protein expression in the rat kidney with subcarcinogenic to carcinogenic doses of bromate.

Kolisetty N, Bull RJ, Muralidhara S, Costyn LJ, Delker DA, Guo Z, Cotruvo JA, Fisher JW, Cummings BS.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):391-8. doi: 10.1016/j.taap.2013.06.018. Epub 2013 Jun 26.

PMID:
23811332
11.

IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease.

Negash AA, Ramos HJ, Crochet N, Lau DT, Doehle B, Papic N, Delker DA, Jo J, Bertoletti A, Hagedorn CH, Gale M Jr.

PLoS Pathog. 2013;9(4):e1003330. doi: 10.1371/journal.ppat.1003330. Epub 2013 Apr 25.

12.

Changes in mRNA and protein expression in the renal cortex of male and female F344 rats treated with bromate.

Kolisetty N, Delker DA, Muralidhara S, Bull RJ, Cotruvo JA, Fisher JW, Cummings BS.

Arch Toxicol. 2013 Nov;87(11):1911-1925. doi: 10.1007/s00204-013-1052-2. Epub 2013 Apr 16.

PMID:
23588252
13.

RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infection.

Papic N, Maxwell CI, Delker DA, Liu S, Heale BS, Hagedorn CH.

Viruses. 2012 Apr;4(4):581-612. doi: 10.3390/v4040581. Epub 2012 Apr 16.

14.

ENCODE tiling array analysis identifies differentially expressed annotated and novel 5' capped RNAs in hepatitis C infected liver.

Folkers ME, Delker DA, Maxwell CI, Nelson CA, Schwartz JJ, Nix DA, Hagedorn CH.

PLoS One. 2011 Feb 16;6(2):e14697. doi: 10.1371/journal.pone.0014697.

15.

Carcinogenic effects of "whole-life" exposure to inorganic arsenic in CD1 mice.

Tokar EJ, Diwan BA, Ward JM, Delker DA, Waalkes MP.

Toxicol Sci. 2011 Jan;119(1):73-83. doi: 10.1093/toxsci/kfq315. Epub 2010 Oct 11.

16.

Oncogene expression profiles in K6/ODC mouse skin and papillomas following a chronic exposure to monomethylarsonous acid.

Delker DA, Geter DR, Roop BC, Ward WO, Ahlborn GJ, Allen JW, Nelson GM, Ouyang M, Welsh W, Chen Y, O'Brien T, Kitchin KT.

J Biochem Mol Toxicol. 2009 Nov-Dec;23(6):406-18. doi: 10.1002/jbt.20304.

PMID:
20024957
17.

Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic.

Nelson GM, Ahlborn GJ, Allen JW, Ren H, Corton JC, Waalkes MP, Kitchin KT, Diwan BA, Knapp G, Delker DA.

Toxicology. 2009 Dec 21;266(1-3):6-15. doi: 10.1016/j.tox.2009.10.004. Epub 2009 Oct 12.

PMID:
19822182
18.

Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H mice.

Ahlborn GJ, Nelson GM, Grindstaff RD, Waalkes MP, Diwan BA, Allen JW, Kitchin KT, Preston RJ, Hernandez-Zavala A, Adair B, Thomas DJ, Delker DA.

Toxicology. 2009 Aug 3;262(2):106-13. doi: 10.1016/j.tox.2009.05.003. Epub 2009 May 18.

19.

Early alterations in protein and gene expression in rat kidney following bromate exposure.

Ahlborn GJ, Delker DA, Roop BC, Geter DR, Allen JW, DeAngelo AB, Winnik WM.

Food Chem Toxicol. 2009 Jun;47(6):1154-60. doi: 10.1016/j.fct.2009.02.003.

PMID:
19425233
20.

Subchronic, reproductive, and developmental toxicity of a fluorotelomer-based urethane polymeric product.

Stadler JC, Delker DA, Malley LA, Frame SR, Everds NE, Mylchreest E, Munley SM, Loveless SE, Buck RC.

Drug Chem Toxicol. 2008;31(3):317-37. doi: 10.1080/01480540701873418 .

PMID:
18622868
21.

Frequency and spectrum of lacI mutations in the liver of Big Blue mice following the administration of genotoxic carcinogens singly and in series.

Delker DA, Geter DR, Kleinert KM, Gollapudi BB.

Int J Toxicol. 2008 Jan-Feb;27(1):35-42. doi: 10.1080/10915810701876620.

PMID:
18293211
22.

Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite.

Ahlborn GJ, Nelson GM, Ward WO, Knapp G, Allen JW, Ouyang M, Roop BC, Chen Y, O'Brien T, Kitchin KT, Delker DA.

Toxicol Appl Pharmacol. 2008 Mar 15;227(3):400-16. doi: 10.1016/j.taap.2007.10.029. Epub 2007 Nov 28.

PMID:
18191166
23.

Folate deficiency enhances arsenic effects on expression of genes involved in epidermal differentiation in transgenic K6/ODC mouse skin.

Nelson GM, Ahlborn GJ, Delker DA, Kitchin KT, O'Brien TG, Chen Y, Kohan MJ, Roop BC, Ward WO, Allen JW.

Toxicology. 2007 Nov 30;241(3):134-45. Epub 2007 Sep 1.

PMID:
17928125
24.
25.

Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.

Allen JW, Wolf DC, George MH, Hester SD, Sun G, Thai SF, Delker DA, Moore T, Jones C, Nelson G, Roop BC, Leavitt S, Winkfield E, Ward WO, Nesnow S.

Toxicol Pathol. 2006;34(7):853-62.

PMID:
17178687
26.

Kidney toxicogenomics of chronic potassium bromate exposure in f344 male rats.

Geter DR, Ward WO, Knapp GW, Deangelo AB, Rubis JA, Owen RD, Allen JW, Delker DA.

Transl Oncogenomics. 2006 Nov 23;1:33-52. Print 2006.

27.

Molecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points.

Glatt CM, Ouyang M, Welsh W, Green JW, Connor JO, Frame SR, Everds NE, Poindexter G, Snajdr S, Delker DA.

Environ Health Perspect. 2005 Oct;113(10):1354-61.

28.
29.

Diallyl sulfide enhances azoxymethane-induced preneoplasia in Fischer 344 rat colon.

Delker DA, Papanikolaou A, Suhr YJ, Rosenberg DW.

Chem Biol Interact. 2000 Feb 1;124(3):149-60.

PMID:
10728775
30.

Azoxymethane induces KI-ras activation in the tumor resistant AKR/J mouse colon.

Bolt AB, Papanikolaou A, Delker DA, Wang QS, Rosenberg DW.

Mol Carcinog. 2000 Mar;27(3):210-8.

PMID:
10708483
31.
32.

Quantitative assessment of azoxymethane-induced aberrant crypt foci in inbred mice.

Delker DA, Wang QS, Papanikolaou A, Whiteley HE, Rosenberg DW.

Exp Mol Pathol. 1999 Feb;65(3):141-9.

PMID:
10234360
33.

The role of alcohol dehydrogenase in the metabolism of the colon carcinogen methylazoxymethanol.

Delker DA, McKnight SJ 3rd, Rosenberg DW.

Toxicol Sci. 1998 Sep;45(1):66-71.

PMID:
9848112
34.

Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility.

Papanikolaou A, Wang QS, Delker DA, Rosenberg DW.

Cancer Lett. 1998 Aug 14;130(1-2):29-34.

PMID:
9751253
35.

Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice.

Papanikolaou A, Shank RC, Delker DA, Povey A, Cooper DP, Rosenberg DW.

Toxicol Appl Pharmacol. 1998 May;150(1):196-203.

PMID:
9630469

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