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Items: 13


Cellular models of alpha-synuclein toxicity and aggregation.

Delenclos M, Burgess JD, Lamprokostopoulou A, Outeiro TF, Vekrellis K, McLean PJ.

J Neurochem. 2019 Sep;150(5):566-576. doi: 10.1111/jnc.14806. Epub 2019 Jul 30. Review.


CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.

Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S.

Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8.


Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain.

Delenclos M, Faroqi AH, Yue M, Kurti A, Castanedes-Casey M, Rousseau L, Phillips V, Dickson DW, Fryer JD, McLean PJ.

Acta Neuropathol Commun. 2017 Jun 23;5(1):51. doi: 10.1186/s40478-017-0455-3.


Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein.

Delenclos M, Trendafilova T, Mahesh D, Baine AM, Moussaud S, Yan IK, Patel T, McLean PJ.

Front Neurosci. 2017 Mar 30;11:172. doi: 10.3389/fnins.2017.00172. eCollection 2017.


A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo.

Delenclos M, Trendafilova T, Jones DR, Moussaud S, Baine AM, Yue M, Hirst WD, McLean PJ.

Front Neurosci. 2016 Jan 19;9:511. doi: 10.3389/fnins.2015.00511. eCollection 2015.


Transmission of Soluble and Insoluble α-Synuclein to Mice.

Jones DR, Delenclos M, Baine AT, DeTure M, Murray ME, Dickson DW, McLean PJ.

J Neuropathol Exp Neurol. 2015 Dec;74(12):1158-69. doi: 10.1097/NEN.0000000000000262.


Untangling a role for tau in synucleinopathies.

Delenclos M, Moussaud S, McLean PJ.

Biol Psychiatry. 2015 Nov 15;78(10):666-7. doi: 10.1016/j.biopsych.2015.08.020. No abstract available.


Biomarkers in Parkinson's disease: Advances and strategies.

Delenclos M, Jones DR, McLean PJ, Uitti RJ.

Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1:S106-10. doi: 10.1016/j.parkreldis.2015.09.048. Epub 2015 Sep 30. Review.


Alpha-synuclein and tau: teammates in neurodegeneration?

Moussaud S, Jones DR, Moussaud-Lamodière EL, Delenclos M, Ross OA, McLean PJ.

Mol Neurodegener. 2014 Oct 29;9:43. doi: 10.1186/1750-1326-9-43. Review.


Immunolocalization of human alpha-synuclein in the Thy1-aSyn ("Line 61") transgenic mouse line.

Delenclos M, Carrascal L, Jensen K, Romero-Ramos M.

Neuroscience. 2014 Sep 26;277:647-64. doi: 10.1016/j.neuroscience.2014.07.042. Epub 2014 Aug 1. Erratum in: Neuroscience. 2015 Jan 29;285:356.


Mapping of the spontaneous deletion in the Ap3d1 gene of mocha mice: fast and reliable genotyping.

Drasbek KR, Holm MM, Delenclos M, Jensen K.

BMC Res Notes. 2008 Nov 25;1:119. doi: 10.1186/1756-0500-1-119.


SSADH deficiency leads to elevated extracellular GABA levels and increased GABAergic neurotransmission in the mouse cerebral cortex.

Drasbek KR, Vardya I, Delenclos M, Gibson KM, Jensen K.

J Inherit Metab Dis. 2008 Dec;31(6):662-8. doi: 10.1007/s10545-008-0941-7. Epub 2008 Aug 15.


Cognitive performance in neurokinin 3 receptor knockout mice.

Nordquist RE, Delenclos M, Ballard TM, Savignac H, Pauly-Evers M, Ozmen L, Spooren W.

Psychopharmacology (Berl). 2008 Jun;198(2):211-20. doi: 10.1007/s00213-008-1119-6. Epub 2008 Mar 20.


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