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Items: 1 to 50 of 137

1.

Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs.

Delecluse S, Yu J, Bernhardt K, Haar J, Poirey R, Tsai MH, Kiblawi R, Kopp-Schneider A, Schnitzler P, Zeier M, Dreger P, Wuchter P, Bulut OC, Behrends U, Delecluse HJ.

PLoS One. 2019 Sep 30;14(9):e0222847. doi: 10.1371/journal.pone.0222847. eCollection 2019.

2.

Epstein-Barr virus ncRNA from a nasopharyngeal carcinoma induces an inflammatory response that promotes virus production.

Li Z, Tsai MH, Shumilov A, Baccianti F, Tsao SW, Poirey R, Delecluse HJ.

Nat Microbiol. 2019 Sep 9. doi: 10.1038/s41564-019-0546-y. [Epub ahead of print]

PMID:
31501540
3.

A single phosphoacceptor residue in BGLF3 is essential for transcription of Epstein-Barr virus late genes.

Li J, Walsh A, Lam TT, Delecluse HJ, El-Guindy A.

PLoS Pathog. 2019 Aug 28;15(8):e1007980. doi: 10.1371/journal.ppat.1007980. eCollection 2019 Aug.

4.

Correction: Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.

Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AKS, Altieri DC, Messick TE, Lieberman PM.

Oncotarget. 2019 Jul 8;10(43):4505-4506. doi: 10.18632/oncotarget.27073. eCollection 2019 Jul 8.

5.

Progress in EBV Vaccines.

van Zyl DG, Mautner J, Delecluse HJ.

Front Oncol. 2019 Feb 25;9:104. doi: 10.3389/fonc.2019.00104. eCollection 2019. Review.

6.

Epstein-Barr Virus Induces Expression of the LPAM-1 Integrin in B Cells In Vitro and In Vivo.

Delecluse S, Tsai MH, Shumilov A, Bencun M, Arrow S, Beshirova A, Cottignies-Calamarte A, Lasitschka F, Bulut OC, Münz C, Zeier M, Behrends U, Delecluse HJ.

J Virol. 2019 Feb 19;93(5). pii: e01618-18. doi: 10.1128/JVI.01618-18. Print 2019 Mar 1.

7.

Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.

van Zyl DG, Tsai MH, Shumilov A, Schneidt V, Poirey R, Schlehe B, Fluhr H, Mautner J, Delecluse HJ.

PLoS Pathog. 2018 Dec 6;14(12):e1007464. doi: 10.1371/journal.ppat.1007464. eCollection 2018 Dec.

8.

Antigen-armed antibodies against B-cell malignancies.

Ilecka M, van Zyl DG, Delecluse HJ.

Oncotarget. 2018 Nov 2;9(86):35601-35602. doi: 10.18632/oncotarget.26276. eCollection 2018 Nov 2. No abstract available.

9.

Antibodies conjugated with viral antigens elicit a cytotoxic T cell response against primary CLL ex vivo.

Schneidt V, Ilecka M, Dreger P, van Zyl DG, Fink S, Mautner J, Delecluse HJ.

Leukemia. 2019 Jan;33(1):88-98. doi: 10.1038/s41375-018-0160-7. Epub 2018 Jun 20.

PMID:
29925906
10.

Translational profiling of B cells infected with the Epstein-Barr virus reveals 5' leader ribosome recruitment through upstream open reading frames.

Bencun M, Klinke O, Hotz-Wagenblatt A, Klaus S, Tsai MH, Poirey R, Delecluse HJ.

Nucleic Acids Res. 2018 Apr 6;46(6):2802-2819. doi: 10.1093/nar/gky129.

11.

Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.

Cirac A, Stützle S, Dieckmeyer M, Adhikary D, Moosmann A, Körber N, Bauer T, Witter K, Delecluse HJ, Behrends U, Mautner J.

Cancer Immunol Immunother. 2018 Apr;67(4):663-674. doi: 10.1007/s00262-018-2118-z. Epub 2018 Jan 27.

PMID:
29374782
12.

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

Gupta S, Ylä-Anttila P, Callegari S, Tsai MH, Delecluse HJ, Masucci MG.

PLoS Pathog. 2018 Jan 22;14(1):e1006852. doi: 10.1371/journal.ppat.1006852. eCollection 2018 Jan.

13.

[The Epstein-Barr virus and the centriole: new tricks from an old dog].

Delecluse HJ, Fink S, Tsai MH, Shumilov A.

Med Sci (Paris). 2017 Jun-Jul;33(6-7):567-569. doi: 10.1051/medsci/20173306003. Epub 2017 Jul 19. French. No abstract available.

14.

Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.

McHugh D, Caduff N, Barros MHM, Rämer PC, Raykova A, Murer A, Landtwing V, Quast I, Styles CT, Spohn M, Fowotade A, Delecluse HJ, Papoudou-Bai A, Lee YM, Kim JM, Middeldorp J, Schulz TF, Cesarman E, Zbinden A, Capaul R, White RE, Allday MJ, Niedobitek G, Blackbourn DJ, Grundhoff A, Münz C.

Cell Host Microbe. 2017 Jul 12;22(1):61-73.e7. doi: 10.1016/j.chom.2017.06.009.

15.

Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)- induced lymphoproliferative disease and lytic viral replication.

Bilger A, Plowshay J, Ma S, Nawandar D, Barlow EA, Romero-Masters JC, Bristol JA, Li Z, Tsai MH, Delecluse HJ, Kenney SC.

Oncotarget. 2017 Jul 4;8(27):44266-44280. doi: 10.18632/oncotarget.17863.

16.

Epstein-Barr virus particles induce centrosome amplification and chromosomal instability.

Shumilov A, Tsai MH, Schlosser YT, Kratz AS, Bernhardt K, Fink S, Mizani T, Lin X, Jauch A, Mautner J, Kopp-Schneider A, Feederle R, Hoffmann I, Delecluse HJ.

Nat Commun. 2017 Feb 10;8:14257. doi: 10.1038/ncomms14257.

17.

Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.

Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AK, Altieri DC, Messick TE, Lieberman PM.

Oncotarget. 2017 Jan 31;8(5):7248-7264. doi: 10.18632/oncotarget.14540. Erratum in: Oncotarget. 2019 Jul 08;10(43):4505-4506.

18.

Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential.

Ma SD, Tsai MH, Romero-Masters JC, Ranheim EA, Huebner SM, Bristol JA, Delecluse HJ, Kenney SC.

J Virol. 2017 Mar 13;91(7). pii: e01928-16. doi: 10.1128/JVI.01928-16. Print 2017 Apr 1.

19.

The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers.

Tsai MH, Lin X, Shumilov A, Bernhardt K, Feederle R, Poirey R, Kopp-Schneider A, Pereira B, Almeida R, Delecluse HJ.

Oncotarget. 2017 Feb 7;8(6):10238-10254. doi: 10.18632/oncotarget.14380.

20.

The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex.

McKenzie J, Lopez-Giraldez F, Delecluse HJ, Walsh A, El-Guindy A.

PLoS Pathog. 2016 Nov 17;12(11):e1006008. doi: 10.1371/journal.ppat.1006008. eCollection 2016 Nov.

21.

Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation.

Kratz AS, Richter KT, Schlosser YT, Schmitt M, Shumilov A, Delecluse HJ, Hoffmann I.

Cell Cycle. 2016 Dec 16;15(24):3419-3431. doi: 10.1080/15384101.2016.1246093. Epub 2016 Oct 18.

22.

The Epstein-Barr virus DNA load in the peripheral blood of transplant recipients does not accurately reflect the burden of infected cells.

Fink S, Tsai MH, Schnitzler P, Zeier M, Dreger P, Wuchter P, Bulut OC, Behrends U, Delecluse HJ.

Transpl Int. 2017 Jan;30(1):57-67. doi: 10.1111/tri.12871. Epub 2016 Nov 5.

23.

PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model.

Ma SD, Xu X, Jones R, Delecluse HJ, Zumwalde NA, Sharma A, Gumperz JE, Kenney SC.

PLoS Pathog. 2016 May 17;12(5):e1005642. doi: 10.1371/journal.ppat.1005642. eCollection 2016 May.

24.

Diagnosis and Treatment of Nasopharyngeal Carcinoma in Children and Adolescents - Recommendations of the GPOH-NPC Study Group.

Kontny U, Franzen S, Behrends U, Bührlen M, Christiansen H, Delecluse H, Eble M, Feuchtinger T, Gademann G, Granzen B, Kratz CP, Lassay L, Leuschner I, Mottaghy FM, Schmitt C, Staatz G, Timmermann B, Vorwerk P, Wilop S, Wolff HA, Mertens R.

Klin Padiatr. 2016 Apr;228(3):105-12. doi: 10.1055/s-0041-111180. Epub 2016 May 2. Review.

PMID:
27135270
25.

A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog.

Bernhardt K, Haar J, Tsai MH, Poirey R, Feederle R, Delecluse HJ.

PLoS Pathog. 2016 Jan 22;12(1):e1005405. doi: 10.1371/journal.ppat.1005405. eCollection 2016 Jan.

26.

The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells.

Lin X, Tsai MH, Shumilov A, Poirey R, Bannert H, Middeldorp JM, Feederle R, Delecluse HJ.

PLoS Pathog. 2015 Dec 22;11(12):e1005344. doi: 10.1371/journal.ppat.1005344. eCollection 2015 Dec.

27.

The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.

Haar J, Contrant M, Bernhardt K, Feederle R, Diederichs S, Pfeffer S, Delecluse HJ.

Nucleic Acids Res. 2016 Feb 18;44(3):1326-41. doi: 10.1093/nar/gkv1330. Epub 2015 Dec 3.

28.

Epstein-Barr Virus BZLF1-Mediated Downregulation of Proinflammatory Factors Is Essential for Optimal Lytic Viral Replication.

Li Y, Long X, Huang L, Yang M, Yuan Y, Wang Y, Delecluse HJ, Kuang E.

J Virol. 2015 Nov 4;90(2):887-903. doi: 10.1128/JVI.01921-15. Print 2016 Jan 15.

29.

Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Types.

Feederle R, Klinke O, Kutikhin A, Poirey R, Tsai MH, Delecluse HJ.

Curr Top Microbiol Immunol. 2015;390(Pt 1):119-48. doi: 10.1007/978-3-319-22822-8_7. Review.

PMID:
26424646
30.

Modulation of MicroRNA Cluster miR-183-96-182 Expression by Epstein-Barr Virus Latent Membrane Protein 1.

Oussaief L, Fendri A, Chane-Woon-Ming B, Poirey R, Delecluse HJ, Joab I, Pfeffer S.

J Virol. 2015 Dec;89(23):12178-88. doi: 10.1128/JVI.01757-15. Epub 2015 Sep 23.

31.

KIT Mutation and Loss of 14q May Be Sufficient for the Development of Clinically Symptomatic Very Low-Risk GIST.

Klinke OK, Mizani T, Baldwin G, Bancel B, Devouassoux-Shisheboran M, Scoazec JY, Bringuier PP, Feederle R, Jauch A, Hinderhofer K, Taniere P, Delecluse HJ.

PLoS One. 2015 Jun 23;10(6):e0130149. doi: 10.1371/journal.pone.0130149. eCollection 2015.

32.

DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA.

Wang'ondu R, Teal S, Park R, Heston L, Delecluse H, Miller G.

PLoS One. 2015 May 7;10(5):e0126088. doi: 10.1371/journal.pone.0126088. eCollection 2015.

33.

Telomerase activity impacts on Epstein-Barr virus infection of AGS cells.

Rac J, Haas F, Schumacher A, Middeldorp JM, Delecluse HJ, Speck RF, Bernasconi M, Nadal D.

PLoS One. 2015 Apr 9;10(4):e0123645. doi: 10.1371/journal.pone.0123645. eCollection 2015.

34.

Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.

Yu X, Ilecka M, Bartlett EJ, Schneidt V, Bhat R, Mautner J, Feederle R, Delecluse HJ.

Blood. 2015 Mar 5;125(10):1601-10. doi: 10.1182/blood-2014-07-591412. Epub 2015 Jan 7.

PMID:
25568348
35.

A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteins.

El-Guindy A, Lopez-Giraldez F, Delecluse HJ, McKenzie J, Miller G.

PLoS Pathog. 2014 Aug 28;10(8):e1004307. doi: 10.1371/journal.ppat.1004307. eCollection 2014 Aug.

36.

Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice.

Antsiferova O, Müller A, Rämer PC, Chijioke O, Chatterjee B, Raykova A, Planas R, Sospedra M, Shumilov A, Tsai MH, Delecluse HJ, Münz C.

PLoS Pathog. 2014 Aug 28;10(8):e1004333. doi: 10.1371/journal.ppat.1004333. eCollection 2014 Aug.

37.

Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins.

Park R, El-Guindy A, Heston L, Lin SF, Yu KP, Nagy M, Borah S, Delecluse HJ, Steitz J, Miller G.

PLoS One. 2014 Apr 4;9(4):e92593. doi: 10.1371/journal.pone.0092593. eCollection 2014.

38.

Genetics of Epstein-Barr virus microRNAs.

Klinke O, Feederle R, Delecluse HJ.

Semin Cancer Biol. 2014 Jun;26:52-9. doi: 10.1016/j.semcancer.2014.02.002. Epub 2014 Mar 3. Review.

PMID:
24602823
39.

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection.

Chijioke O, Müller A, Feederle R, Barros MH, Krieg C, Emmel V, Marcenaro E, Leung CS, Antsiferova O, Landtwing V, Bossart W, Moretta A, Hassan R, Boyman O, Niedobitek G, Delecluse HJ, Capaul R, Münz C.

Cell Rep. 2013 Dec 26;5(6):1489-98. doi: 10.1016/j.celrep.2013.11.041. Epub 2013 Dec 19. Erratum in: Cell Rep. 2015 Aug 4;12(5):901.

40.

Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas.

Tsai MH, Raykova A, Klinke O, Bernhardt K, Gärtner K, Leung CS, Geletneky K, Sertel S, Münz C, Feederle R, Delecluse HJ.

Cell Rep. 2013 Oct 31;5(2):458-70. doi: 10.1016/j.celrep.2013.09.012. Epub 2013 Oct 10.

41.

Latency of Epstein-Barr virus is disrupted by gain-of-function mutant cellular AP-1 proteins that preferentially bind methylated DNA.

Yu KP, Heston L, Park R, Ding Z, Wang'ondu R, Delecluse HJ, Miller G.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8176-81. doi: 10.1073/pnas.1301577110. Epub 2013 Apr 26.

42.

A cluster of virus-encoded microRNAs accelerates acute systemic Epstein-Barr virus infection but does not significantly enhance virus-induced oncogenesis in vivo.

Wahl A, Linnstaedt SD, Esoda C, Krisko JF, Martinez-Torres F, Delecluse HJ, Cullen BR, Garcia JV.

J Virol. 2013 May;87(10):5437-46. doi: 10.1128/JVI.00281-13. Epub 2013 Mar 6.

43.

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.

Hernando H, Shannon-Lowe C, Islam AB, Al-Shahrour F, Rodríguez-Ubreva J, Rodríguez-Cortez VC, Javierre BM, Mangas C, Fernández AF, Parra M, Delecluse HJ, Esteller M, López-Granados E, Fraga MF, López-Bigas N, Ballestar E.

Genome Biol. 2013 Jan 15;14(1):R3. doi: 10.1186/gb-2013-14-1-r3.

44.

An Epstein-Barr virus mutant produces immunogenic defective particles devoid of viral DNA.

Pavlova S, Feederle R, Gärtner K, Fuchs W, Granzow H, Delecluse HJ.

J Virol. 2013 Feb;87(4):2011-22. doi: 10.1128/JVI.02533-12. Epub 2012 Dec 12.

45.

Essential role of Rta in lytic DNA replication of Epstein-Barr virus.

El-Guindy A, Ghiassi-Nejad M, Golden S, Delecluse HJ, Miller G.

J Virol. 2013 Jan;87(1):208-23. doi: 10.1128/JVI.01995-12. Epub 2012 Oct 17.

46.

Epidemiology and morbidity of Epstein-Barr virus infection in pediatric renal transplant recipients: a multicenter, prospective study.

Höcker B, Fickenscher H, Delecluse HJ, Böhm S, Küsters U, Schnitzler P, Pohl M, John U, Kemper MJ, Fehrenbach H, Wigger M, Holder M, Schröder M, Billing H, Fichtner A, Feneberg R, Sander A, Köpf-Shakib S, Süsal C, Tönshoff B.

Clin Infect Dis. 2013 Jan;56(1):84-92. doi: 10.1093/cid/cis823. Epub 2012 Oct 5.

PMID:
23042966
47.

Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.

Heath E, Begue-Pastor N, Chaganti S, Croom-Carter D, Shannon-Lowe C, Kube D, Feederle R, Delecluse HJ, Rickinson AB, Bell AI.

PLoS Pathog. 2012;8(5):e1002697. doi: 10.1371/journal.ppat.1002697. Epub 2012 May 10.

48.

The viral and cellular microRNA targetome in lymphoblastoid cell lines.

Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler U, Cullen BR.

PLoS Pathog. 2012 Jan;8(1):e1002484. doi: 10.1371/journal.ppat.1002484. Epub 2012 Jan 26.

49.

EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription.

Tsai K, Thikmyanova N, Wojcechowskyj JA, Delecluse HJ, Lieberman PM.

PLoS Pathog. 2011 Nov;7(11):e1002376. doi: 10.1371/journal.ppat.1002376. Epub 2011 Nov 10.

50.

The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes.

Feederle R, Haar J, Bernhardt K, Linnstaedt SD, Bannert H, Lips H, Cullen BR, Delecluse HJ.

J Virol. 2011 Oct;85(19):9801-10. doi: 10.1128/JVI.05100-11. Epub 2011 Jul 13.

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