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Items: 1 to 50 of 56

1.

The Webcam system: a simple, automated, computer-based video system for quantitative measurement of movement in nonhuman primates.

Togasaki DM, Hsu A, Samant M, Farzan B, DeLanney LE, Langston JW, Di Monte DA, Quik M.

J Neurosci Methods. 2005 Jun 30;145(1-2):159-66.

PMID:
15922034
2.

Aging of the nigrostriatal system in the squirrel monkey.

McCormack AL, Di Monte DA, Delfani K, Irwin I, DeLanney LE, Langston WJ, Janson AM.

J Comp Neurol. 2004 Apr 12;471(4):387-95.

PMID:
15022260
3.

Novel observations with FDOPA-PET imaging after early nigrostriatal damage.

Yee RE, Irwin I, Milonas C, Stout DB, Huang SC, Shoghi-Jadid K, Satyamurthy N, Delanney LE, Togasaki DM, Farahani KF, Delfani K, Janson AM, Phelps ME, Langston JW, Barrio JR.

Mov Disord. 2001 Sep;16(5):838-48.

PMID:
11746613
4.

Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations.

Yee RE, Huang SC, Stout DB, Irwin I, Shoghi-Jadid K, Togaski DM, DeLanney LE, Langston JW, Satyamurthy N, Farahani KF, Phelps ME, Barrio JR.

J Neurochem. 2000 Mar;74(3):1147-57.

5.

Cutaneous mastocytomas in the neotenic caudate amphibians Ambystoma mexicanum (axolotl) and Ambystoma tigrinum (tiger salamander).

Harshbarger JC, Chang SC, DeLanney LE, Rose FL, Green DE.

J Cancer Res Clin Oncol. 1999;125(3-4):187-92.

PMID:
10235473
6.

Monoamine oxidase-dependent metabolism of dopamine in the striatum and substantia nigra of L-DOPA-treated monkeys.

Di Monte DA, DeLanney LE, Irwin I, Royland JE, Chan P, Jakowec MW, Langston JW.

Brain Res. 1996 Oct 28;738(1):53-9.

PMID:
8949927
7.

Electron microscopy of Lewy bodies in the amygdala-parahippocampal region. Comparison with inclusion bodies in the MPTP-treated squirrel monkey.

Forno LS, DeLanney LE, Irwin I, Langston JW.

Adv Neurol. 1996;69:217-28. No abstract available.

PMID:
8615131
8.

Age-dependent effects of the 2'-methyl analog of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine: prevention by inhibitors of monoamine oxidase B.

Finnegan KT, Irwin I, Delanney LE, Langston JW.

J Pharmacol Exp Ther. 1995 May;273(2):716-20.

PMID:
7752075
10.

Aging and the nigrostriatal dopamine system: a non-human primate study.

Irwin I, DeLanney LE, McNeill T, Chan P, Forno LS, Murphy GM Jr, Di Monte DA, Sandy MS, Langston JW.

Neurodegeneration. 1994 Dec;3(4):251-65.

PMID:
7531106
11.

Evolution of nerve fiber degeneration in the striatum in the MPTP-treated squirrel monkey.

Forno LS, DeLanney LE, Irwin I, Langston JW.

Mol Neurobiol. 1994 Aug-Dec;9(1-3):163-70.

PMID:
7888093
12.

Rapid ATP loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity.

Chan P, Di Monte DA, Luo JJ, DeLanney LE, Irwin I, Langston JW.

J Neurochem. 1994 Jun;62(6):2484-7.

PMID:
8189253
13.

2-deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain.

Chan P, Langston JW, Irwin I, DeLanney LE, Di Monte DA.

J Neurochem. 1993 Aug;61(2):610-6.

PMID:
8336145
14.

Early-stage loss of dopamine uptake-site binding in MPTP-treated monkeys.

Graybiel AM, Moratalla R, Quinn B, DeLanney LE, Irwin I, Langston JW.

Adv Neurol. 1993;60:34-9. No abstract available.

PMID:
8420148
15.

MPTP and aging. Studies in the C57BL/6 mouse.

Irwin I, DeLanney LE, Langston JW.

Adv Neurol. 1993;60:197-206. No abstract available.

PMID:
8420136
16.
17.

MPTP-induced ATP loss in mouse brain.

Chan P, DeLanney LE, Irwin I, Langston JW, Di Monte D.

Ann N Y Acad Sci. 1992 May 11;648:306-8. No abstract available.

PMID:
1637060
18.

Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Moratalla R, Quinn B, DeLanney LE, Irwin I, Langston JW, Graybiel AM.

Proc Natl Acad Sci U S A. 1992 May 1;89(9):3859-63.

19.

Toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.

Di Monte DA, Wu EY, Delanney LE, Irwin I, Langston JW.

J Pharmacol Exp Ther. 1992 Apr;261(1):44-9.

PMID:
1560384
20.

The relationships between aging, monoamine oxidase, striatal dopamine and the effects of MPTP in C57BL/6 mice: a critical reassessment.

Irwin I, Finnegan KT, Delanney LE, Di Monte D, Langston JW.

Brain Res. 1992 Feb 14;572(1-2):224-31.

PMID:
1611516
21.

Production and disposition of 1-methyl-4-phenylpyridinium in primary cultures of mouse astrocytes.

Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.

Glia. 1992;5(1):48-55.

PMID:
1311704
22.

Astrocytes and Parkinson's disease.

Forno LS, DeLanney LE, Irwin I, Di Monte D, Langston JW.

Prog Brain Res. 1992;94:429-36. Review. No abstract available.

PMID:
1287728
23.

Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.

Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.

J Pharmacol Exp Ther. 1991 Aug;258(2):594-600.

PMID:
1907660
24.

Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain.

Chan P, DeLanney LE, Irwin I, Langston JW, Di Monte D.

J Neurochem. 1991 Jul;57(1):348-51.

PMID:
2051170
25.

Mechanism of accumulation of the 1-methyl-4-phenylpyridinium species into mouse brain synaptosomes.

Scotcher KP, Irwin I, DeLanney LE, Langston JW, Di Monte D.

J Neurochem. 1991 May;56(5):1602-7.

PMID:
2013755
26.

The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey.

Irwin I, DeLanney LE, Forno LS, Finnegan KT, Di Monte DA, Langston JW.

Brain Res. 1990 Oct 29;531(1-2):242-52.

PMID:
1981162
27.

Modulating role of dopamine on anesthetic requirements.

Segal IS, Walton JK, Irwin I, DeLanney LE, Ricaurte GA, Langston JW, Maze M.

Eur J Pharmacol. 1990 Sep 4;186(1):9-15.

PMID:
2282937
28.

Protection against DSP-4-induced neurotoxicity by deprenyl is not related to its inhibition of MAO B.

Finnegan KT, Skratt JJ, Irwin I, DeLanney LE, Langston JW.

Eur J Pharmacol. 1990 Aug 2;184(1):119-26.

PMID:
2120076
29.

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on ATP levels of mouse brain synaptosomes.

Scotcher KP, Irwin I, DeLanney LE, Langston JW, Di Monte D.

J Neurochem. 1990 Apr;54(4):1295-301.

PMID:
2313288
30.

The amine-depleting effects of 5,7-dihydroxytryptamine (5,7-DHT) in C57BL/6 mice do not increase with age.

Finnegan KT, DeLanney LE, Irwin I, Ricaurte GA, Langston JW.

Brain Res. 1989 Sep 4;496(1-2):251-6.

PMID:
2804634
31.

Diethyldithiocarbamate and disulfiram inhibit MPP+ and dopamine uptake by striatal synaptosomes.

Di Monte D, Irwin I, Kupsch A, Cooper S, DeLanney LE, Langston JW.

Eur J Pharmacol. 1989 Jul 4;166(1):23-9.

PMID:
2553428
32.

Evaluation of the neurotoxic potential of N,N-dimethylamphetamine: an illicit analog of methamphetamine.

Ricaurte GA, DeLanney LE, Irwin I, Witkin JM, Katz JL, Langston JW.

Brain Res. 1989 Jun 26;490(2):301-6.

PMID:
2765865
33.

The biodisposition of MPP+ in mouse brain.

Irwin I, DeLanney LE, Di Monte D, Langston JW.

Neurosci Lett. 1989 Jun 5;101(1):83-8.

PMID:
2788838
34.
35.

(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates.

Ricaurte GA, Forno LS, Wilson MA, DeLanney LE, Irwin I, Molliver ME, Langston JW.

JAMA. 1988 Jul 1;260(1):51-5.

PMID:
2454332
36.

An electron microscopic study of MPTP-induced inclusion bodies in an old monkey.

Forno LS, Langston JW, DeLanney LE, Irwin I.

Brain Res. 1988 May 10;448(1):150-7.

PMID:
3260534
37.

The sensitivity of nigrostriatal dopamine neurons to MPP+ does not increase with age.

Irwin I, Ricaurte GA, DeLanney LE, Langston JW.

Neurosci Lett. 1988 Apr 22;87(1-2):51-6.

PMID:
3260017
38.

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration.

Ricaurte GA, DeLanney LE, Irwin I, Langston JW.

Brain Res. 1988 Apr 12;446(1):165-8.

PMID:
2897228
39.

The dopamine-depleting effect of 6-hydroxydopamine does not increase with aging.

Ricaurte GA, DeLanney LE, Finnegan KT, Irwin I, Langston JW.

Brain Res. 1988 Jan 12;438(1-2):395-8.

PMID:
3125947
40.

The effect of diethyldithiocarbamate on the biodisposition of MPTP: an explanation for enhanced neurotoxicity.

Irwin I, Wu EY, DeLanney LE, Trevor A, Langston JW.

Eur J Pharmacol. 1987 Sep 11;141(2):209-17.

PMID:
2824216
41.

1,2,3,6-tetrahydro-1-methyl-4-(methylpyrrol-2-yl)pyridine: studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Finnegan KT, Irwin I, Delanney LE, Ricaurte GA, Langston JW.

J Pharmacol Exp Ther. 1987 Sep;242(3):1144-51.

PMID:
3498815
42.

3,4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain.

Ricaurte GA, Finnegan KF, Nichols DE, DeLanney LE, Irwin I, Langston JW.

Eur J Pharmacol. 1987 Jun 4;137(2-3):265-8.

PMID:
2886355
43.

The biotransformation of MPTP and disposition of MPP+: the effects of aging.

Langston JW, Irwin I, DeLanney LE.

Life Sci. 1987 Feb 23;40(8):749-54.

PMID:
3492654
44.

4-Phenylpyridine (4PP) and MPTP: the relationship between striatal MPP+ concentrations and neurotoxicity.

Irwin I, Langston JW, DeLanney LE.

Life Sci. 1987 Feb 23;40(8):731-40.

PMID:
3492652
45.

Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra.

Ricaurte GA, Irwin I, Forno LS, DeLanney LE, Langston E, Langston JW.

Brain Res. 1987 Feb 10;403(1):43-51.

PMID:
3493827
46.

Older dopaminergic neurons do not recover from the effects of MPTP.

Ricaurte GA, DeLanney LE, Irwin I, Langston JW.

Neuropharmacology. 1987 Jan;26(1):97-9.

PMID:
3494208
47.

Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.

Forno LS, Langston JW, DeLanney LE, Irwin I, Ricaurte GA.

Ann Neurol. 1986 Oct;20(4):449-55.

PMID:
3024555
48.

Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment.

Ricaurte GA, Langston JW, Delanney LE, Irwin I, Peroutka SJ, Forno LS.

Brain Res. 1986 Jun 18;376(1):117-24.

PMID:
3487376
49.

Dopamine uptake blockers protect against the dopamine depleting effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse striatum.

Ricaurte GA, Langston JW, DeLanney LE, Irwin I, Brooks JD.

Neurosci Lett. 1985 Sep 6;59(3):259-64.

PMID:
3932903
50.

A steady efflux of ionic current predicts hind limb development in the axolotl.

Borgens RB, Rouleau MF, DeLanney LE.

J Exp Zool. 1983 Dec;228(3):491-503.

PMID:
6663262

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