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Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner.

Bian K, Delaney JC, Zhou X, Li D.

Toxics. 2019 Jun 25;7(2). pii: E36. doi: 10.3390/toxics7020036. Review.


Body Mass Index From Early-, Mid-, and Older-Adulthood and Risk of Heart Failure and Atherosclerotic Cardiovascular Disease: MESA.

Fliotsos M, Zhao D, Rao VN, Ndumele CE, Guallar E, Burke GL, Vaidya D, Delaney JCA, Michos ED.

J Am Heart Assoc. 2018 Nov 20;7(22):e009599. doi: 10.1161/JAHA.118.009599.


Antibody-Bactericidal Macrocyclic Peptide Conjugates To Target Gram-Negative Bacteria.

Touti F, Lautrette G, Johnson KD, Delaney JC, Wollacott A, Tissire H, Viswanathan K, Shriver Z, Mong SK, Mijalis AJ, Plante OJ, Pentelute BL.

Chembiochem. 2018 Oct 4;19(19):2039-2044. doi: 10.1002/cbic.201800295. Epub 2018 Sep 14.


Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1-Methyladenine and 3-Methylcytosine.

Tang Q, Cai A, Bian K, Chen F, Delaney JC, Adusumalli S, Bach AC 2nd, Akhlaghi F, Cho BP, Li D.

ACS Omega. 2017 Nov 30;2(11):8205-8212. doi: 10.1021/acsomega.7b01482. Epub 2017 Nov 20.


Behavioral activation in TFP: The role of the treatment contract in transference-focused psychotherapy.

Yeomans FE, Delaney JC, Levy KN.

Psychotherapy (Chic). 2017 Sep;54(3):260-266. doi: 10.1037/pst0000118.


Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV.

Noorhasan M, Drozd DR, Grunfeld C, Merrill JO, Burkholder GA, Mugavero MJ, Willig JH, Willig AL, Cropsey KL, Mayer KH, Blashill A, Mimiaga M, McCaul ME, Hutton H, Chander G, Mathews WC, Napravnik S, Eron JJ, Christopoulos K, Fredericksen RJ, Nance RM, Delaney JC, Crane PK, Saag MS, Kitahata MM, Crane HM.

AIDS Res Hum Retroviruses. 2017 Jun;33(6):534-545. doi: 10.1089/AID.2015.0357. Epub 2017 Feb 16.


Poorly Controlled HIV Infection: An Independent Risk Factor for Liver Fibrosis.

Kim HN, Nance R, Van Rompaey S, Delaney JC, Crane HM, Cachay ER, Geng E, Boswell SL, Rodriguez B, Eron JJ, Saag M, Moore RD, Kitahata MM.

J Acquir Immune Defic Syndr. 2016 Aug 1;72(4):437-43. doi: 10.1097/QAI.0000000000000992.


Utility of Nontraditional Risk Markers in Atherosclerotic Cardiovascular Disease Risk Assessment.

Yeboah J, Young R, McClelland RL, Delaney JC, Polonsky TS, Dawood FZ, Blaha MJ, Miedema MD, Sibley CT, Carr JJ, Burke GL, Goff DC Jr, Psaty BM, Greenland P, Herrington DM.

J Am Coll Cardiol. 2016 Jan 19;67(2):139-147. doi: 10.1016/j.jacc.2015.10.058.


A broadly neutralizing human monoclonal antibody is effective against H7N9.

Tharakaraman K, Subramanian V, Viswanathan K, Sloan S, Yen HL, Barnard DL, Leung YH, Szretter KJ, Koch TJ, Delaney JC, Babcock GJ, Wogan GN, Sasisekharan R, Shriver Z.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10890-5. doi: 10.1073/pnas.1502374112. Epub 2015 Aug 17.


Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.

Fedeles BI, Freudenthal BD, Yau E, Singh V, Chang SC, Li D, Delaney JC, Wilson SH, Essigmann JM.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4571-80. doi: 10.1073/pnas.1507709112. Epub 2015 Aug 4.


Utility of Nontraditional Risk Markers in Individuals Ineligible for Statin Therapy According to the 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines.

Yeboah J, Polonsky TS, Young R, McClelland RL, Delaney JC, Dawood F, Blaha MJ, Miedema MD, Sibley CT, Carr JJ, Burke GL, Goff DC Jr, Psaty BM, Greenland P, Herrington DM.

Circulation. 2015 Sep 8;132(10):916-22. doi: 10.1161/CIRCULATIONAHA.115.016846. Epub 2015 Jul 29.


The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.

Fedeles BI, Singh V, Delaney JC, Li D, Essigmann JM.

J Biol Chem. 2015 Aug 21;290(34):20734-42. doi: 10.1074/jbc.R115.656462. Epub 2015 Jul 7. Review.


Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.

Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, Essigmann JM.

Nucleic Acids Res. 2015 Jun 23;43(11):5489-500. doi: 10.1093/nar/gkv243. Epub 2015 Apr 2.


Implications of the new American College of Cardiology/American Heart Association cholesterol guidelines for primary atherosclerotic cardiovascular disease event prevention in a multi ethnic cohort: Multi-Ethnic Study of Atherosclerosis (MESA).

Yeboah J, Sillau S, Delaney JC, Blaha MJ, Michos ED, Young R, Qureshi WT, McClelland R, Burke GL, Psaty BM, Herrington DM.

Am Heart J. 2015 Mar;169(3):387-395.e3. doi: 10.1016/j.ahj.2014.12.018. Epub 2015 Jan 6.


Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses.

Hendricks GL, Velazquez L, Pham S, Qaisar N, Delaney JC, Viswanathan K, Albers L, Comolli JC, Shriver Z, Knipe DM, Kurt-Jones EA, Fygenson DK, Trevejo JM, Wang JP, Finberg RW.

Antiviral Res. 2015 Apr;116:34-44. doi: 10.1016/j.antiviral.2015.01.008. Epub 2015 Jan 28.


Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.

Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM.

Chem Res Toxicol. 2014 Sep 15;27(9):1619-31. doi: 10.1021/tx5002817. Epub 2014 Aug 26.


Development of a new diabetes risk prediction tool for incident coronary heart disease events: the Multi-Ethnic Study of Atherosclerosis and the Heinz Nixdorf Recall Study.

Yeboah J, Erbel R, Delaney JC, Nance R, Guo M, Bertoni AG, Budoff M, Moebus S, Jöckel KH, Burke GL, Wong ND, Lehmann N, Herrington DM, Möhlenkamp S, Greenland P.

Atherosclerosis. 2014 Oct;236(2):411-7. doi: 10.1016/j.atherosclerosis.2014.07.035. Epub 2014 Aug 14.


A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo.

Shrivastav N, Fedeles BI, Li D, Delaney JC, Frick LE, Foti JJ, Walker GC, Essigmann JM.

PLoS One. 2014 Apr 14;9(4):e94716. doi: 10.1371/journal.pone.0094716. eCollection 2014.


Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB.

Li D, Fedeles BI, Shrivastav N, Delaney JC, Yang X, Wong C, Drennan CL, Essigmann JM.

Chem Res Toxicol. 2013 Aug 19;26(8):1182-7. doi: 10.1021/tx400096m. Epub 2013 Jul 10.


Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB.

Li D, Delaney JC, Page CM, Yang X, Chen AS, Wong C, Drennan CL, Essigmann JM.

J Am Chem Soc. 2012 May 30;134(21):8896-901. doi: 10.1021/ja3010094. Epub 2012 May 21.


Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.

Rechkoblit O, Delaney JC, Essigmann JM, Patel DJ.

Structure. 2011 Jun 8;19(6):821-32. doi: 10.1016/j.str.2011.03.020.


Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry.

Li D, Delaney JC, Page CM, Chen AS, Wong C, Drennan CL, Essigmann JM.

J Nucleic Acids. 2010 Oct 27;2010:369434. doi: 10.4061/2010/369434.


A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase.

Jarosz DF, Cohen SE, Delaney JC, Essigmann JM, Walker GC.

Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21137-42. doi: 10.1073/pnas.0907257106. Epub 2009 Nov 30.


Efficient replication bypass of size-expanded DNA base pairs in bacterial cells.

Delaney JC, Gao J, Liu H, Shrivastav N, Essigmann JM, Kool ET.

Angew Chem Int Ed Engl. 2009;48(25):4524-7. doi: 10.1002/anie.200805683.


Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).

Lee CY, Delaney JC, Kartalou M, Lingaraju GM, Maor-Shoshani A, Essigmann JM, Samson LD.

Biochemistry. 2009 Mar 10;48(9):1850-61. doi: 10.1021/bi8018898.


Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate.

Mundle ST, Delaney JC, Essigmann JM, Strauss PR.

Biochemistry. 2009 Jan 13;48(1):19-26. doi: 10.1021/bi8016137.


[Some factors affecting treatment outcome in a randomized clinical trial of borderline patients].

Delaney JC, Yeomans F, Stone MH, Haran C.

Sante Ment Que. 2008 Spring;33(1):15-36. French.


[Transference focused psychotherapy].

Yeomans F, Delaney JC, Renaud A.

Sante Ment Que. 2007 Spring;32(1):17-34. French.


Biological properties of single chemical-DNA adducts: a twenty year perspective.

Delaney JC, Essigmann JM.

Chem Res Toxicol. 2008 Jan;21(1):232-52. Epub 2007 Dec 12. Review.


Mismatch repair proteins collaborate with methyltransferases in the repair of O(6)-methylguanine.

Rye PT, Delaney JC, Netirojjanakul C, Sun DX, Liu JZ, Essigmann JM.

DNA Repair (Amst). 2008 Feb 1;7(2):170-6. Epub 2007 Oct 24.


Chemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite.

Delaney S, Delaney JC, Essigmann JM.

Chem Res Toxicol. 2007 Nov;20(11):1718-29. Epub 2007 Oct 18.


Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli.

Patro JN, Wiederholt CJ, Jiang YL, Delaney JC, Essigmann JM, Greenberg MM.

Biochemistry. 2007 Sep 4;46(35):10202-12. Epub 2007 Aug 11.


AlkB influences the chloroacetaldehyde-induced mutation spectra and toxicity in the pSP189 supF shuttle vector.

Kim MY, Zhou X, Delaney JC, Taghizadeh K, Dedon PC, Essigmann JM, Wogan GN.

Chem Res Toxicol. 2007 Aug;20(8):1075-83. Epub 2007 Jul 20.


DNA polymerase V allows bypass of toxic guanine oxidation products in vivo.

Neeley WL, Delaney S, Alekseyev YO, Jarosz DF, Delaney JC, Walker GC, Essigmann JM.

J Biol Chem. 2007 Apr 27;282(17):12741-8. Epub 2007 Feb 24.


The substrate specificity of MutY for hyperoxidized guanine lesions in vivo.

Delaney S, Neeley WL, Delaney JC, Essigmann JM.

Biochemistry. 2007 Feb 6;46(5):1448-55.


Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB.

Frick LE, Delaney JC, Wong C, Drennan CL, Essigmann JM.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):755-60. Epub 2007 Jan 9.


A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates.

Jarosz DF, Godoy VG, Delaney JC, Essigmann JM, Walker GC.

Nature. 2006 Jan 12;439(7073):225-8.


Probing the active site tightness of DNA polymerase in subangstrom increments.

Kim TW, Delaney JC, Essigmann JM, Kool ET.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15803-8. Epub 2005 Oct 25.


AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo.

Delaney JC, Smeester L, Wong C, Frick LE, Taghizadeh K, Wishnok JS, Drennan CL, Samson LD, Essigmann JM.

Nat Struct Mol Biol. 2005 Oct;12(10):855-60. Epub 2005 Oct 2.


Urea lesion formation in DNA as a consequence of 7,8-dihydro-8-oxoguanine oxidation and hydrolysis provides a potent source of point mutations.

Henderson PT, Neeley WL, Delaney JC, Gu F, Niles JC, Hah SS, Tannenbaum SR, Essigmann JM.

Chem Res Toxicol. 2005 Jan;18(1):12-8.


In vivo bypass efficiencies and mutational signatures of the guanine oxidation products 2-aminoimidazolone and 5-guanidino-4-nitroimidazole.

Neeley WL, Delaney JC, Henderson PT, Essigmann JM.

J Biol Chem. 2004 Oct 15;279(42):43568-73. Epub 2004 Aug 6.


The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo.

Henderson PT, Delaney JC, Muller JG, Neeley WL, Tannenbaum SR, Burrows CJ, Essigmann JM.

Biochemistry. 2003 Aug 12;42(31):9257-62.


High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds.

Delaney JC, Henderson PT, Helquist SA, Morales JC, Essigmann JM, Kool ET.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4469-73. Epub 2003 Apr 3.


Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo.

Henderson PT, Delaney JC, Gu F, Tannenbaum SR, Essigmann JM.

Biochemistry. 2002 Jan 22;41(3):914-21.


The development of a psychodynamic treatment for patients with borderline personality disorder: a preliminary study of behavioral change.

Clarkin JF, Foelsch PA, Levy KN, Hull JW, Delaney JC, Kernberg OF.

J Pers Disord. 2001 Dec;15(6):487-95.


Effect of sequence context on O(6)-methylguanine repair and replication in vivo.

Delaney JC, Essigmann JM.

Biochemistry. 2001 Dec 11;40(49):14968-75.


Simultaneous bilateral spontaneous pneumothoraces in a young woman with anorexia nervosa.

Corless JA, Delaney JC, Page RD.

Int J Eat Disord. 2001 Jul;30(1):110-2.


A pulmonary mass and hyperviscosity.

Corless JA, Allsup DJ, Deeble TJ, Delaney JC.

Postgrad Med J. 2000 Sep;76(899):582, 587. No abstract available.

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