Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 111

1.

Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation.

Hassani Z, Saleh A, Turpault S, Khiati S, Morelle W, Vignon J, Hugnot JP, Uro-Coste E, Legrand P, Delaforge M, Loiseau S, Clarion L, Lecouvey M, Volle JN, Virieux D, Pirat JL, Duffau H, Bakalara N.

Mol Cancer Res. 2017 Oct;15(10):1376-1387. doi: 10.1158/1541-7786.MCR-17-0120. Epub 2017 Jun 20.

2.

Evidencing 98 secondary metabolites of Penicillium verrucosum using substrate isotopic labeling and high-resolution mass spectrometry.

Hautbergue T, Puel O, Tadrist S, Meneghetti L, Péan M, Delaforge M, Debrauwer L, Oswald IP, Jamin EL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Dec 15;1071:29-43. doi: 10.1016/j.jchromb.2017.03.011. Epub 2017 Mar 12.

PMID:
28351740
3.

Lactococcus lactis is an Efficient Expression System for Mammalian Membrane Proteins Involved in Liver Detoxification, CYP3A4, and MGST1.

Bakari S, Lembrouk M, Sourd L, Ousalem F, André F, Orlowski S, Delaforge M, Frelet-Barrand A.

Mol Biotechnol. 2016 Apr;58(4):299-310. doi: 10.1007/s12033-016-9928-z.

PMID:
26961909
4.

Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.

Nguyen TT, Bénech H, Delaforge M, Lenuzza N.

Pharm Stat. 2016 Mar-Apr;15(2):165-77. doi: 10.1002/pst.1731. Epub 2015 Dec 22.

PMID:
26689604
5.

Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.

Lenuzza N, Duval X, Nicolas G, Thévenot E, Job S, Videau O, Narjoz C, Loriot MA, Beaune P, Becquemont L, Mentré F, Funck-Brentano C, Alavoine L, Arnaud P, Delaforge M, Bénech H.

Eur J Drug Metab Pharmacokinet. 2016 Apr;41(2):125-38. doi: 10.1007/s13318-014-0239-0. Epub 2014 Dec 3.

PMID:
25465228
6.

New untargeted metabolic profiling combining mass spectrometry and isotopic labeling: application on Aspergillus fumigatus grown on wheat.

Cano PM, Jamin EL, Tadrist S, Bourdaud'hui P, Péan M, Debrauwer L, Oswald IP, Delaforge M, Puel O.

Anal Chem. 2013 Sep 3;85(17):8412-20. doi: 10.1021/ac401872f. Epub 2013 Aug 20.

PMID:
23901908
7.

Metabolic detoxification pathways for 5-methoxy-sterigmatocystin in primary tracheal epithelial cells.

Cabaret O, Puel O, Botterel F, Delaforge M, Bretagne S.

Xenobiotica. 2014 Jan;44(1):1-9. doi: 10.3109/00498254.2013.804635. Epub 2013 Jun 11.

PMID:
23756242
8.

Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry.

Bussy U, Delaforge M, El-Bekkali C, Ferchaud-Roucher V, Krempf M, Tea I, Galland N, Jacquemin D, Boujtita M.

Anal Bioanal Chem. 2013 Jul;405(18):6077-85. doi: 10.1007/s00216-013-7050-7. Epub 2013 May 23.

PMID:
23700103
9.

Jewelry boxes contaminated by Aspergillus oryzae: an occupational health risk?

Bellanger AP, Roussel A, Millon L, Delaforge M, Reboux G.

J Occup Environ Hyg. 2012;9(7):460-6. doi: 10.1080/15459624.2012.691332.

PMID:
22702230
10.

Cytochrome P450-catalyzed degradation of nicotine: fundamental parameters determining hydroxylation by cytochrome P450 2A6 at the 5'-carbon or the n-methyl carbon.

Kwiecień RA, Le Questel JY, Lebreton J, Delaforge M, André F, Pihan E, Roussel A, Fournial A, Paneth P, Robins RJ.

J Phys Chem B. 2012 Jul 12;116(27):7827-40. doi: 10.1021/jp304276v. Epub 2012 Jun 29.

PMID:
22676413
11.

Microbiological evaluation of ten French archives and link to occupational symptoms.

Roussel S, Reboux G, Millon L, Parchas MD, Boudih S, Skana F, Delaforge M, Rakotonirainy MS.

Indoor Air. 2012 Dec;22(6):514-22. doi: 10.1111/j.1600-0668.2012.00781.x. Epub 2012 Apr 18.

PMID:
22429323
12.

Can a cocktail designed for phenotyping pharmacokinetics and metabolism enzymes in human be used efficiently in rat?

Videau O, Pitarque S, Troncale S, Hery P, Thévenot E, Delaforge M, Bénech H.

Xenobiotica. 2012 Apr;42(4):349-54. doi: 10.3109/00498254.2011.625453. Epub 2012 Feb 9.

PMID:
22321050
13.

Contribution of uniformly 13C-enriched sterigmatocystin to the study of its pulmonary metabolism.

Cabaret O, Puel O, Botterel F, Pean M, Bretagne S, Delaforge M.

Rapid Commun Mass Spectrom. 2011 Oct 15;25(19):2704-10. doi: 10.1002/rcm.5068.

PMID:
21913247
14.

Metabolism of N-methyl-amide by cytochrome P450s: formation and characterization of highly stable carbinol-amide intermediate.

Perrin L, Loiseau N, André F, Delaforge M.

FEBS J. 2011 Jun;278(12):2167-78. doi: 10.1111/j.1742-4658.2011.08133.x. Epub 2011 May 19.

15.

Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells.

Cabaret O, Puel O, Botterel F, Pean M, Khoufache K, Costa JM, Delaforge M, Bretagne S.

Chem Res Toxicol. 2010 Nov 15;23(11):1673-81. doi: 10.1021/tx100127b. Epub 2010 Oct 7.

PMID:
20929267
16.

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.

Videau O, Delaforge M, Levi M, Thévenot E, Gal O, Becquemont L, Beaune P, Bénech H.

Rapid Commun Mass Spectrom. 2010 Aug 30;24(16):2407-19. doi: 10.1002/rcm.4641.

PMID:
20658680
17.

In vivo effects of zearalenone on the expression of proteins involved in the detoxification of rat xenobiotics.

Duca RC, Mabondzo A, Bravin F, Delaforge M.

Environ Toxicol. 2012 Feb;27(2):98-108. doi: 10.1002/tox.20617. Epub 2010 Jul 6.

PMID:
20607812
18.

Development of a new HPLC method used for determination of zearalenone and its metabolites in broiler samples. Influence of zearalenone on the nutritional properties of broiler meat.

Duca RC, Bravin F, Delaforge M, Vladescu L, Badea IA, Criste RD.

J Agric Food Chem. 2009 Nov 25;57(22):10497-504. doi: 10.1021/jf9014608.

PMID:
19877635
19.

ABCC1, ABCC2 and ABCC3 are implicated in the transepithelial transport of the myco-estrogen zearalenone and its major metabolites.

Videmann B, Mazallon M, Prouillac C, Delaforge M, Lecoeur S.

Toxicol Lett. 2009 Oct 28;190(2):215-23. doi: 10.1016/j.toxlet.2009.07.021. Epub 2009 Jul 30.

PMID:
19647055
20.
21.

Intramolecular hydrogen bonding as a determinant of the inhibitory potency of N-unsubstituted imidazole derivatives towards mammalian hemoproteins.

Perrin L, André F, Aninat C, Ricoux R, Mahy JP, Shangguan N, Joullié MM, Delaforge M.

Metallomics. 2009 Mar;1(2):148-56. doi: 10.1039/b817743k. Epub 2008 Nov 27.

PMID:
21305108
22.

Metabolism of phenylahistin enantiomers by cytochromes P450: a possible explanation for their different cytotoxicity.

Perrin L, Aninat C, Hamon V, Hayashi Y, Abadie C, Heyd B, André F, Delaforge M.

Drug Metab Dispos. 2008 Nov;36(11):2381-92. doi: 10.1124/dmd.107.019919. Epub 2008 Aug 7.

PMID:
18687804
23.

Isolation and cytotoxicity of low-molecular-weight metabolites of Candida albicans.

Kosalec I, Puel O, Delaforge M, Kopjar N, Antolovic R, Jelic D, Matica B, Galtier P, Pepeljnjak S.

Front Biosci. 2008 May 1;13:6893-904.

PMID:
18508703
24.

Improvement of cyclophosphamide activation by CYP2B6 mutants: from in silico to ex vivo.

Nguyen TA, Tychopoulos M, Bichat F, Zimmermann C, Flinois JP, Diry M, Ahlberg E, Delaforge M, Corcos L, Beaune P, Dansette P, André F, de Waziers I.

Mol Pharmacol. 2008 Apr;73(4):1122-33. doi: 10.1124/mol.107.042861. Epub 2008 Jan 22. Erratum in: Mol Pharmacol. 2008 Jun;73(6):1866.

PMID:
18212249
25.

Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells.

Khoufache K, Puel O, Loiseau N, Delaforge M, Rivollet D, Coste A, Cordonnier C, Escudier E, Botterel F, Bretagne S.

BMC Microbiol. 2007 Jan 23;7:5.

26.

The inability of Byssochlamys fulva to produce patulin is related to absence of 6-methylsalicylic acid synthase and isoepoxydon dehydrogenase genes.

Puel O, Tadrist S, Delaforge M, Oswald IP, Lebrihi A.

Int J Food Microbiol. 2007 Apr 10;115(2):131-9. Epub 2006 Dec 13.

PMID:
17169453
27.

Hydroperoxide characterisation as a signature of the micelle/monomer balance in radiation-induced peroxidation of arachidonate.

Vitrac H, Hauville C, Collin F, Couturier M, Thérond P, Delaforge M, Rémita S, Jore D, Gardès-Albert M.

Free Radic Res. 2005 May;39(5):519-28.

PMID:
16036328
28.

Oxidative metabolism by P450 and function coupling to efflux systems: modulation of mycotoxin toxicity.

Aninat C, André F, Delaforge M.

Food Addit Contam. 2005 Apr;22(4):361-8. Review.

PMID:
16019806
29.

The INSERM expert review on glycol ethers: findings and recommendations.

Multigner L, Catala M, Cordier S, Delaforge M, Fenaux P, Garnier R, Rico-Lattes I, Vasseur P; INSERM (French Institute of Health and Medical Research).

Toxicol Lett. 2005 Mar 28;156(1):29-37.

PMID:
15705485
30.

Byssochlamys nivea as a source of mycophenolic acid.

Puel O, Tadrist S, Galtier P, Oswald IP, Delaforge M.

Appl Environ Microbiol. 2005 Jan;71(1):550-3.

31.
32.

Parameters and mechanistic studies on the oxidative ring cleavage of synthetic heterocyclic naphthoquinones by Streptomyces strains.

Fosse C, Le Texier L, Roy S, Delaforge M, Grégoire S, Neuwels M, Azerad R.

Appl Microbiol Biotechnol. 2004 Sep;65(4):446-56. Epub 2004 Jun 16.

PMID:
15205932
33.

Predicting the conformational states of cyclic tetrapeptides.

Loiseau N, Gomis JM, Santolini J, Delaforge M, André F.

Biopolymers. 2003 Jul;69(3):363-85.

PMID:
12833263
34.

Characterization of two pharmacophores on the multidrug transporter P-glycoprotein.

Garrigues A, Loiseau N, Delaforge M, Ferté J, Garrigos M, André F, Orlowski S.

Mol Pharmacol. 2002 Dec;62(6):1288-98.

PMID:
12435795
35.

Synthesis of a fluorine-18-labelled derivative of 6-nitroquipazine, as a radioligand for the in vivo serotonin transporter imaging with PET.

Karramkam M, Dollé F, Valette H, Besret L, Bramoullé Y, Hinnen F, Vaufrey F, Franklin C, Bourg S, Coulon C, Ottaviani M, Delaforge M, Loc'h C, Bottlaender M, Crouzel C.

Bioorg Med Chem. 2002 Aug;10(8):2611-23.

PMID:
12057650
36.

Structure-activity relationships of cyclotetrapeptides: interaction of tentoxin derivatives with three membrane proteins.

Loiseau N, Delaforge M, Minoletti C, André F, Garrigues A, Orlowski S, Gomis JM.

Adv Exp Med Biol. 2001;500:343-6. No abstract available.

PMID:
11764966
37.

Inhibitory effects of roquefortine on hepatic cytochromes P450.

Aninat C, Delaforge M.

Adv Exp Med Biol. 2001;500:331-4. No abstract available.

PMID:
11764963
38.

Oxidative stress and the structure/activity relationships of ergopeptide alkaloids.

Bensaude F, Bouillé G, Delaforge M.

Adv Exp Med Biol. 2001;500:221-4. No abstract available.

PMID:
11764940
39.

Molecular requirements for inhibition of cytochrome p450 activities by roquefortine.

Aninat C, Hayashi Y, André F, Delaforge M.

Chem Res Toxicol. 2001 Sep;14(9):1259-65.

PMID:
11559041
40.

Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes.

Vadon-Le Goff S, Delaforge M, Boucher JL, Janosik M, Kraus JP, Mansuy D.

Biochem Biophys Res Commun. 2001 May 4;283(2):487-92.

PMID:
11327727
41.

Recognition and oxidative metabolism of cyclodipeptides by hepatic cytochrome P450.

Delaforge M, Bouillé G, Jaouen M, Jankowski CK, Lamouroux C, Bensoussan C.

Peptides. 2001 Apr;22(4):557-65.

PMID:
11311724
42.
43.

Ornithine alpha-ketoglutarate counteracts the decrease of liver cytochrome P-450 content in burned rats.

Roch-Arveiller M, Fontagné J, Coudray-Lucas C, Le Boucher J, Cynober L, Muntaner O, Delaforge M.

Nutrition. 1999 May;15(5):379-83.

PMID:
10355851
44.

The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation.

Rouaud C, Delaforge M, Anger-Leroy M, Le Filliatre G, Finet M, Hanf R.

Br J Pharmacol. 1999 Jan;126(1):35-44.

45.

Importance of metabolism in pharmacological studies: possible in vitro predictability.

Delaforge M.

Nucl Med Biol. 1998 Nov;25(8):705-9. Review.

PMID:
9863553
46.

Conformational analysis of ketolide, conformations of RU 004 in solution and bound to bacterial ribosomes.

Bertho G, Gharbi-Benarous J, Delaforge M, Lang C, Parent A, Girault JP.

J Med Chem. 1998 Aug 27;41(18):3373-86.

PMID:
9719590
48.
49.

Oxidation of tetrahydro-beta-carboline by cytochrome P-450cam--determination and rationalisation of product distribution.

Sopková-de Oliveira Santos J, Smith JC, Delaforge M, Virelizier H, Jankowski CK.

Eur J Biochem. 1998 Jan 15;251(1-2):398-404. Erratum in: Eur J Biochem 1998 Aug 15;256(1):251.

50.

Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen.

Renodon A, Boucher JL, Sari MA, Delaforge M, Ouazzani J, Mansuy D.

Biochem Pharmacol. 1997 Nov 15;54(10):1109-14.

PMID:
9464453

Supplemental Content

Loading ...
Support Center