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Items: 1 to 50 of 339

1.

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

Di Paolo A, Gori G, Tascini C, Danesi R, Del Tacca M.

Clin Pharmacokinet. 2013 Jul;52(7):511-42. doi: 10.1007/s40262-013-0062-9. Review.

PMID:
23605634
2.

The emerging role of sunitinib in the treatment of advanced epithelial thyroid cancer: our experience and review of literature.

Pasqualetti G, Ricci S, Dardano A, Ferdeghini M, Del Tacca M, Monzani F.

Mini Rev Med Chem. 2011 Aug;11(9):746-52. Review.

PMID:
21707530
3.

Linezolid in the central nervous system: comparison between cerebrospinal fluid and plasma pharmacokinetics.

Viaggi B, Paolo AD, Danesi R, Polillo M, Ciofi L, Del Tacca M, Malacarne P.

Scand J Infect Dis. 2011 Sep;43(9):721-7. doi: 10.3109/00365548.2011.582140. Epub 2011 May 17.

PMID:
21585240
4.

Synergistic cytotoxicity, inhibition of signal transduction pathways and pharmacogenetics of sorafenib and gemcitabine in human NSCLC cell lines.

Pasqualetti G, Ricciardi S, Mey V, Del Tacca M, Danesi R.

Lung Cancer. 2011 Nov;74(2):197-205. doi: 10.1016/j.lungcan.2011.03.003. Epub 2011 May 6.

PMID:
21529991
5.

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo.

Canu B, Fioravanti A, Orlandi P, Di Desidero T, Alì G, Fontanini G, Di Paolo A, Del Tacca M, Danesi R, Bocci G.

Neoplasia. 2011 Mar;13(3):217-29.

6.

Time-dependent pharmacokinetics of 5-fluorouracil and association with treatment tolerability in the adjuvant setting of colorectal cancer.

Ibrahim T, Di Paolo A, Amatori F, Mercatali L, Ravaioli E, Flamini E, Sacanna E, Del Tacca M, Danesi R, Amadori D.

J Clin Pharmacol. 2012 Mar;52(3):361-9. doi: 10.1177/0091270010396710. Epub 2011 Mar 7.

PMID:
21383342
7.

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

Azzariti A, Bocci G, Porcelli L, Fioravanti A, Sini P, Simone GM, Quatrale AE, Chiarappa P, Mangia A, Sebastian S, Del Bufalo D, Del Tacca M, Paradiso A.

Br J Cancer. 2011 Mar 1;104(5):769-80. doi: 10.1038/bjc.2011.21. Epub 2011 Feb 8.

8.

Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.

Antonioli L, Fornai M, Colucci R, Awwad O, Ghisu N, Tuccori M, Del Tacca M, Blandizzi C.

Eur J Pharmacol. 2011 Jan 15;650(2-3):639-49. doi: 10.1016/j.ejphar.2010.10.041. Epub 2010 Oct 27.

PMID:
21034735
9.

Esomeprazole-induced hyperchromograninemia in the absence of concomitant hypergastrinemia.

Gori G, Spinelli G, Spinelli C, Tuccori M, Blandizzi C, Del Tacca M.

Nat Rev Gastroenterol Hepatol. 2010 Nov;7(11):642-6. doi: 10.1038/nrgastro.2010.152. Epub 2010 Oct 12.

PMID:
20938461
10.

Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells.

Ricciardi S, Mey V, Nannizzi S, Pasqualetti G, Crea F, Del Tacca M, Danesi R.

Chemotherapy. 2010;56(4):303-12. doi: 10.1159/000320031. Epub 2010 Aug 13.

PMID:
20714148
11.

Augmentation of clozapine with aripiprazole in severe psychotic bipolar and schizoaffective disorders: a pilot study.

Benedetti A, Di Paolo A, Lastella M, Casamassima F, Candiracci C, Litta A, Ciofi L, Danesi R, Lattanzi L, Del Tacca M, Cassano GB.

Clin Pract Epidemiol Ment Health. 2010 Jun 4;6:30-5. doi: 10.2174/1745017901006010030.

12.

Pharmacological issues of linezolid: an updated critical review.

Di Paolo A, Malacarne P, Guidotti E, Danesi R, Del Tacca M.

Clin Pharmacokinet. 2010 Jul;49(7):439-47. doi: 10.2165/11319960-000000000-00000. Review.

PMID:
20528004
13.

Healthy volunteers and early phases of clinical experimentation.

Pasqualetti G, Gori G, Blandizzi C, Del Tacca M.

Eur J Clin Pharmacol. 2010 Jul;66(7):647-53. doi: 10.1007/s00228-010-0827-0. Epub 2010 May 12. Review.

PMID:
20461363
14.

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma.

Polillo M, Tascini C, Lastella M, Malacarne P, Ciofi L, Viaggi B, Bocci G, Menichetti F, Danesi R, Del Tacca M, Di Paolo A.

Ther Drug Monit. 2010 Apr;32(2):200-5. doi: 10.1097/FTD.0b013e3181d3f5cb.

PMID:
20216115
15.

Targeting vascular endothelial growth factor pathway in first-line treatment of metastatic colorectal cancer: state-of-the-art and future perspectives in clinical and molecular selection of patients.

Loupakis F, Bocci G, Pasqualetti G, Fornaro L, Salvatore L, Cremolini C, Masi G, Danesi R, Del Tacca M, Falcone A.

Curr Cancer Drug Targets. 2010 Feb;10(1):37-45. Review.

PMID:
20088795
16.

Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.

Nannizzi S, Veal GJ, Giovannetti E, Mey V, Ricciardi S, Ottley CJ, Del Tacca M, Danesi R.

Cancer Chemother Pharmacol. 2010 Aug;66(3):547-58. doi: 10.1007/s00280-009-1195-2. Epub 2009 Dec 18.

17.

Periorbital necrotising fasciitis.

Lazzeri D, Lazzeri S, Figus M, Tascini C, Bocci G, Colizzi L, Giannotti G, Lorenzetti F, Gandini D, Danesi R, Menichetti F, Del Tacca M, Nardi M, Pantaloni M.

Br J Ophthalmol. 2010 Dec;94(12):1577-85. doi: 10.1136/bjo.2009.167486. Epub 2009 Nov 5. Review.

PMID:
19897473
18.

Emerging role of cyclooxygenase isoforms in the control of gastrointestinal neuromuscular functions.

Fornai M, Antonioli L, Colucci R, Bernardini N, Ghisu N, Tuccori M, De Giorgio R, Del Tacca M, Blandizzi C.

Pharmacol Ther. 2010 Jan;125(1):62-78. doi: 10.1016/j.pharmthera.2009.09.007. Epub 2009 Oct 4. Review.

PMID:
19808045
19.

Progressive multifocal leukoencephalopathy: a report of three cases in HIV-negative patients with non-Hodgkin's lymphomas treated with rituximab.

Tuccori M, Focosi D, Maggi F, Cosottini M, Meini B, Lena F, Blandizzi C, Del Tacca M, Petrini M.

Ann Hematol. 2010 May;89(5):519-22. doi: 10.1007/s00277-009-0819-2. Epub 2009 Aug 29. No abstract available.

PMID:
19727726
20.

Safety concerns associated with the use of serotonin reuptake inhibitors and other serotonergic/noradrenergic antidepressants during pregnancy: a review.

Tuccori M, Testi A, Antonioli L, Fornai M, Montagnani S, Ghisu N, Colucci R, Corona T, Blandizzi C, Del Tacca M.

Clin Ther. 2009 Jun;31 Pt 1:1426-53. doi: 10.1016/j.clinthera.2009.07.009. Review.

PMID:
19698902
21.

Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.

Fioravanti A, Canu B, Alì G, Orlandi P, Allegrini G, Di Desidero T, Emmenegger U, Fontanini G, Danesi R, Del Tacca M, Falcone A, Bocci G.

Eur J Pharmacol. 2009 Oct 1;619(1-3):8-14. doi: 10.1016/j.ejphar.2009.08.020. Epub 2009 Aug 18.

PMID:
19695243
22.

Re: Rituximab maintenance for the treatment of patients with follicular lymphoma: systematic review and meta-analysis of randomized trials.

Tuccori M, Focosi D, Blandizzi C, Del Tacca M, Petrini M.

J Natl Cancer Inst. 2009 Sep 16;101(18):1288-9; author reply 1289-90. doi: 10.1093/jnci/djp256. Epub 2009 Aug 17. No abstract available.

PMID:
19687414
23.

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients.

Consoli G, Lastella M, Ciapparelli A, Catena Dell'Osso M, Ciofi L, Guidotti E, Danesi R, Dell'Osso L, Del Tacca M, Di Paolo A.

Pharmacogenomics. 2009 Aug;10(8):1267-76. doi: 10.2217/pgs.09.51.

PMID:
19663671
24.

Discordant somatic and germline VEGF-A genotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis.

Coltelli L, Allegrini G, Orlandi P, Giuntini N, Alì G, Fioravanti A, Bona E, Barletta MT, Fontanini G, Del Tacca M, Danesi R, Falcone A, Bocci G.

Pharmacogenomics. 2009 Aug;10(8):1225-9. doi: 10.2217/pgs.09.55.

PMID:
19663667
25.

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

Del Tacca M, Pasqualetti G, Di Paolo A, Virdis A, Massimetti G, Gori G, Versari D, Taddei S, Blandizzi C.

Br J Clin Pharmacol. 2009 Jul;68(1):34-42. doi: 10.1111/j.1365-2125.2009.03399.x.

26.

Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer.

Ferrandina G, Mey V, Nannizzi S, Ricciardi S, Petrillo M, Ferlini C, Danesi R, Scambia G, Del Tacca M.

Cancer Chemother Pharmacol. 2010 Mar;65(4):679-86. doi: 10.1007/s00280-009-1073-y. Epub 2009 Jul 29.

PMID:
19639316
27.

Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

Fontana A, Galli L, Fioravanti A, Orlandi P, Galli C, Landi L, Bursi S, Allegrini G, Fontana E, Di Marsico R, Antonuzzo A, D'Arcangelo M, Danesi R, Del Tacca M, Falcone A, Bocci G.

Clin Cancer Res. 2009 Aug 1;15(15):4954-62. doi: 10.1158/1078-0432.CCR-08-3317. Epub 2009 Jul 21.

28.

Three-times weekly teicoplanin as outpatient treatment of chronic osteoarticular infections.

Tascini C, Tagliaferri E, Di Paolo A, Ciofi L, Del Tacca M, Lambelet P, Menichetti F.

J Chemother. 2009 Aug;21(4):421-5.

PMID:
19622461
29.

Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.

Crea F, Giovannetti E, Cortesi F, Mey V, Nannizzi S, Gallegos Ruiz MI, Ricciardi S, Del Tacca M, Peters GJ, Danesi R.

Mol Cancer Ther. 2009 Jul;8(7):1964-73. doi: 10.1158/1535-7163.MCT-09-0027. Epub 2009 Jun 16.

30.

Genetic polymorphisms of thiopurine S-methyltransferase in a cohort of patients with systemic autoimmune diseases.

Tani C, Mosca M, Colucci R, Gori G, d'Ascanio A, Ghisu N, Fornai M, Di Paolo A, Blandizzi C, Del Tacca M, Bombardieri S.

Clin Exp Rheumatol. 2009 Mar-Apr;27(2):321-4.

PMID:
19473575
31.

Single nucleotide polymorphisms and clinical outcome in patients with biliary tract carcinoma treated with epirubicin, cisplatin and capecitabine.

Pacetti P, Giovannetti E, Mambrini A, Nannizzi S, Orlandi M, Tartarini R, Del Freo A, Del Tacca M, Danesi R, Cantore M.

Anticancer Res. 2009 May;29(5):1835-40.

32.

Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids.

Virdis A, Colucci R, Versari D, Ghisu N, Fornai M, Antonioli L, Duranti E, Daghini E, Giannarelli C, Blandizzi C, Taddei S, Del Tacca M.

Hypertension. 2009 Jun;53(6):1008-16. doi: 10.1161/HYPERTENSIONAHA.109.132258. Epub 2009 Apr 20.

PMID:
19380610
33.

Pharmacogenomics in non-small-cell lung cancer chemotherapy.

Danesi R, Pasqualetti G, Giovannetti E, Crea F, Altavilla G, Del Tacca M, Rosell R.

Adv Drug Deliv Rev. 2009 May 20;61(5):408-17. doi: 10.1016/j.addr.2009.03.001. Epub 2009 Mar 16. Review.

PMID:
19292993
34.

Characterization of mechanisms underlying the effects of esomeprazole on the impairment of gastric ulcer healing with addition of NSAID treatment.

Colucci R, Fornai M, Antonioli L, Ghisu N, Tuccori M, Blandizzi C, Del Tacca M.

Dig Liver Dis. 2009 Jun;41(6):395-405. doi: 10.1016/j.dld.2008.10.004. Epub 2009 Feb 28.

PMID:
19251492
35.

Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.

La Motta C, Sartini S, Mugnaini L, Salerno S, Simorini F, Taliani S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Antonioli L, Fornai M, Blandizzi C, Del Tacca M.

J Med Chem. 2009 Mar 26;52(6):1681-92. doi: 10.1021/jm801427r.

PMID:
19226143
36.

Role of coxibs in the strategies for gastrointestinal protection in patients requiring chronic non-steroidal anti-inflammatory therapy.

Blandizzi C, Tuccori M, Colucci R, Fornai M, Antonioli L, Ghisu N, Del Tacca M.

Pharmacol Res. 2009 Feb;59(2):90-100. doi: 10.1016/j.phrs.2008.11.004. Epub 2008 Nov 27. Review.

PMID:
19073262
37.

Statin-associated psychiatric adverse events: a case/non-case evaluation of an Italian database of spontaneous adverse drug reaction reporting.

Tuccori M, Lapi F, Testi A, Coli D, Moretti U, Vannacci A, Motola D, Salvo F, Rivolta AL, Blandizzi C, Mugelli A, Del Tacca M.

Drug Saf. 2008;31(12):1115-23. doi: 10.2165/0002018-200831120-00007.

PMID:
19026028
38.

A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon.

Fornai M, Antonioli L, Colucci R, Ghisu N, Buccianti P, Marioni A, Chiarugi M, Tuccori M, Blandizzi C, Del Tacca M.

Neurogastroenterol Motil. 2009 Apr;21(4):451-66. doi: 10.1111/j.1365-2982.2008.01213.x. Epub 2008 Oct 25.

PMID:
19019012
39.

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction.

Bocci G, Di Paolo A, Barbara C, Masi G, Fornaro L, Loupakis F, Allegrini G, Falcone A, Del Tacca M, Danesi R.

Br J Clin Pharmacol. 2009 Jan;67(1):132-4. doi: 10.1111/j.1365-2125.2008.03307.x. Epub 2008 Nov 5. No abstract available.

40.

Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats.

Virdis A, Colucci R, Fornai M, Polini A, Daghini E, Duranti E, Ghisu N, Versari D, Dardano A, Blandizzi C, Taddei S, Del Tacca M, Monzani F.

Endocrinology. 2009 Feb;150(2):1033-42. doi: 10.1210/en.2008-1112. Epub 2008 Oct 16.

PMID:
18927216
41.

Effects of pantoprazole on ulcer healing delay associated with NSAID treatment.

Fornai M, Colucci R, Antonioli L, Ghisu N, Tuccori M, Blandizzi C, Del Tacca M.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Mar;379(3):305-13. doi: 10.1007/s00210-008-0355-y. Epub 2008 Oct 14.

PMID:
18853145
42.

Regulation of enteric functions by adenosine: pathophysiological and pharmacological implications.

Antonioli L, Fornai M, Colucci R, Ghisu N, Tuccori M, Del Tacca M, Blandizzi C.

Pharmacol Ther. 2008 Dec;120(3):233-53. doi: 10.1016/j.pharmthera.2008.08.010. Epub 2008 Sep 14. Review.

PMID:
18848843
43.

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

Fornaro L, Masi G, Bursi S, Loupakis F, Vasile E, Antonuzzo A, Chiara S, Pfanner E, Di Paolo A, Bocci G, Del Tacca M, Falcone A.

Cancer Chemother Pharmacol. 2009 Apr;63(5):965-9. doi: 10.1007/s00280-008-0840-5. Epub 2008 Oct 7.

PMID:
18839174
44.

Severe thrombocytopenia and haemolytic anaemia associated with ciprofloxacin: a case report with fatal outcome.

Tuccori M, Guidi B, Carulli G, Blandizzi C, Del Tacca M, Di Paolo M.

Platelets. 2008 Aug;19(5):384-7. doi: 10.1080/09537100801993040.

PMID:
18791946
45.

Effects of a bicarbonate-alkaline mineral water on digestive motility in experimental models of functional and inflammatory gastrointestinal disorders.

Fornai M, Colucci R, Antonioli L, Ghisu N, Tuccori M, Gori G, Blandizzi C, Del Tacca M.

Methods Find Exp Clin Pharmacol. 2008 May;30(4):261-9. doi: 10.1358/mf.2008.30.4.1159650.

PMID:
18773120
46.

Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients.

Di Paolo A, Bocci G, Danesi R, Del Tacca M.

Curr Clin Pharmacol. 2006 Sep;1(3):311-23. Review.

PMID:
18666754
47.

Serotonin syndrome and the T102-->C polymorphism of the 5-HT2A receptor: a case report.

Lattanzi L, Danesi R, Lastella M, Mungai F, Di Paolo A, Tuccori M, Cassano GB, Del Tacca M.

Bipolar Disord. 2008 Jul;10(5):655-6. doi: 10.1111/j.1399-5618.2008.00598.x. No abstract available.

PMID:
18657250
48.

Endocrinology and art. Queen Ankhesenammon with goiter.

Martino E, Del Tacca M.

J Endocrinol Invest. 2008 Jun;31(6):583. No abstract available.

PMID:
18591896
49.

Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation.

Colucci R, Blandizzi C, Ghisu N, Florio T, Del Tacca M.

Br J Pharmacol. 2008 Sep;155(2):198-209. doi: 10.1038/bjp.2008.268. Epub 2008 Jun 30.

50.

The genetics of the serotonin transporter and irritable bowel syndrome.

Colucci R, Blandizzi C, Bellini M, Ghisu N, Tonini M, Del Tacca M.

Trends Mol Med. 2008 Jul;14(7):295-304. doi: 10.1016/j.molmed.2008.05.001. Epub 2008 Jun 10. Review.

PMID:
18550438

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