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Items: 48

1.

Anomeric sugar boronic acid analogues as potential agents for boron neutron capture therapy.

Imperio D, Del Grosso E, Fallarini S, Lombardi G, Panza L.

Beilstein J Org Chem. 2019 Jun 19;15:1355-1359. doi: 10.3762/bjoc.15.135. eCollection 2019.

2.

Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method.

Canavesi R, Miggiano R, Stella M, Galli U, Rossi F, Rizzi M, Del Grosso E.

J Pharm Biomed Anal. 2019 Sep 5;173:154-161. doi: 10.1016/j.jpba.2019.05.025. Epub 2019 May 13.

PMID:
31129535
3.

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines.

Galli U, Hysenlika R, Meneghetti F, Del Grosso E, Pelliccia S, Novellino E, Giustiniano M, Tron GC.

Molecules. 2019 May 21;24(10). pii: E1959. doi: 10.3390/molecules24101959.

4.

Programmable RNA-based systems for sensing and diagnostic applications.

Rossetti M, Del Grosso E, Ranallo S, Mariottini D, Idili A, Bertucci A, Porchetta A.

Anal Bioanal Chem. 2019 Jul;411(19):4293-4302. doi: 10.1007/s00216-019-01622-7. Epub 2019 Feb 8. Review.

PMID:
30734852
5.

Fuel-Responsive Allosteric DNA-Based Aptamers for the Transient Release of ATP and Cocaine.

Del Grosso E, Ragazzon G, Prins LJ, Ricci F.

Angew Chem Int Ed Engl. 2019 Apr 16;58(17):5582-5586. doi: 10.1002/anie.201812885. Epub 2019 Mar 6.

PMID:
30715777
6.

Remote Electronic Control of DNA-Based Reactions and Nanostructure Assembly.

Amodio A, Del Grosso E, Troina A, Placidi E, Ricci F.

Nano Lett. 2018 May 9;18(5):2918-2923. doi: 10.1021/acs.nanolett.8b00179. Epub 2018 Apr 5.

PMID:
29608313
7.

Dissipative Synthetic DNA-Based Receptors for the Transient Loading and Release of Molecular Cargo.

Del Grosso E, Amodio A, Ragazzon G, Prins LJ, Ricci F.

Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10489-10493. doi: 10.1002/anie.201801318. Epub 2018 May 2.

PMID:
29603570
8.

Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects.

Bianchi M, Canavesi R, Aprile S, Grosa G, Del Grosso E.

J Pharm Biomed Anal. 2018 Feb 20;150:248-257. doi: 10.1016/j.jpba.2017.12.018. Epub 2017 Dec 9.

PMID:
29258044
9.

"One-pot" ethyl chloroformate derivatization and liquid-liquid extraction of reduced glutathione in erythrocyte and its quantitative GC-MS analysis.

Manca A, Alladio E, Massarenti P, Puccinelli MP, De Francesco A, Del Grosso E, Mengozzi G, Pazzi M, Vincenti M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Dec 1;1070:15-22. doi: 10.1016/j.jchromb.2017.10.030. Epub 2017 Oct 20.

PMID:
29100759
10.

Proneurogenic Effects of Trazodone in Murine and Human Neural Progenitor Cells.

Bortolotto V, Mancini F, Mangano G, Salem R, Xia E, Del Grosso E, Bianchi M, Canonico PL, Polenzani L, Grilli M.

ACS Chem Neurosci. 2017 Sep 20;8(9):2027-2038. doi: 10.1021/acschemneuro.7b00175. Epub 2017 Jul 3.

11.

New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone.

Aprile S, Canavesi R, Matucci R, Bellucci C, Del Grosso E, Grosa G.

Xenobiotica. 2018 May;48(5):478-487. doi: 10.1080/00498254.2017.1342288. Epub 2017 Jul 6.

PMID:
28608746
12.

Synthesis and Degradation of Adenosine 5'-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases.

Amici A, Grolla AA, Del Grosso E, Bellini R, Bianchi M, Travelli C, Garavaglia S, Sorci L, Raffaelli N, Ruggieri S, Genazzani AA, Orsomando G.

Cell Chem Biol. 2017 May 18;24(5):553-564.e4. doi: 10.1016/j.chembiol.2017.03.010. Epub 2017 Apr 13.

13.

Synthesis of Sugar-Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy.

Imperio D, Del Grosso E, Fallarini S, Lombardi G, Panza L.

Org Lett. 2017 Apr 7;19(7):1678-1681. doi: 10.1021/acs.orglett.7b00382. Epub 2017 Mar 28.

PMID:
28350469
14.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

Travelli C, Aprile S, Rahimian R, Grolla AA, Rogati F, Bertolotti M, Malagnino F, di Paola R, Impellizzeri D, Fusco R, Mercalli V, Massarotti A, Stortini G, Terrazzino S, Del Grosso E, Fakhfouri G, Troiani MP, Alisi MA, Grosa G, Sorba G, Canonico PL, Orsomando G, Cuzzocrea S, Genazzani AA, Galli U, Tron GC.

J Med Chem. 2017 Mar 9;60(5):1768-1792. doi: 10.1021/acs.jmedchem.6b01392. Epub 2017 Feb 22.

PMID:
28165742
15.

A modular clamp-like mechanism to regulate the activity of nucleic-acid target-responsive nanoswitches with external activators.

Del Grosso E, Idili A, Porchetta A, Ricci F.

Nanoscale. 2016 Oct 27;8(42):18057-18061.

PMID:
27714163
16.

Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products.

Aprile S, Canavesi R, Bianchi M, Grosa G, Del Grosso E.

J Pharm Biomed Anal. 2017 Jan 5;132:66-71. doi: 10.1016/j.jpba.2016.09.037. Epub 2016 Sep 26.

PMID:
27697571
17.

New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement.

Canavesi R, Aprile S, Giovenzana GB, Di Sotto A, Di Giacomo S, Del Grosso E, Grosa G.

Eur J Pharm Sci. 2016 Mar 10;84:123-31. doi: 10.1016/j.ejps.2016.01.015. Epub 2016 Jan 18.

PMID:
26796144
18.

Enzyme-Operated DNA-Based Nanodevices.

Del Grosso E, Dallaire AM, Vallée-Bélisle A, Ricci F.

Nano Lett. 2015 Dec 9;15(12):8407-11. doi: 10.1021/acs.nanolett.5b04566. Epub 2015 Nov 25.

19.

Solution-phase parallel synthesis of aryloxyimino amides via a novel multicomponent reaction among aromatic (Z)-chlorooximes, isocyanides, and electron-deficient phenols.

Mercalli V, Giustiniano M, Del Grosso E, Varese M, Cassese H, Massarotti A, Novellino E, Tron GC.

ACS Comb Sci. 2014 Nov 10;16(11):602-5. doi: 10.1021/co5000882. Epub 2014 Oct 22.

PMID:
25319356
20.

Are 1,4- and 1,5-disubstituted 1,2,3-triazoles good pharmacophoric groups?

Massarotti A, Aprile S, Mercalli V, Del Grosso E, Grosa G, Sorba G, Tron GC.

ChemMedChem. 2014 Nov;9(11):2497-508. doi: 10.1002/cmdc.201402233. Epub 2014 Jul 30.

PMID:
25079879
21.

Erythrocyte glutathione transferase: a non-antibody biomarker for systemic sclerosis, which correlates with severity and activity of the disease.

Fabrini R, Rosato E, Gigante A, Bocedi A, Cianci R, Barbano B, Del Grosso E, Ricci F, Zingaretti V, Salsano F, Ricci G.

Cell Death Dis. 2013 Jul 25;4:e736. doi: 10.1038/cddis.2013.255.

22.

The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force.

Bocedi A, Fabrini R, Farrotti A, Stella L, Ketterman AJ, Pedersen JZ, Allocati N, Lau PC, Grosse S, Eltis LD, Ruzzini A, Edwards TE, Morici L, Del Grosso E, Guidoni L, Bovi D, Lo Bello M, Federici G, Parker MW, Board PG, Ricci G.

J Biol Chem. 2013 Aug 23;288(34):24936-47. doi: 10.1074/jbc.M113.476135. Epub 2013 Jul 3.

23.

Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites.

Aprile S, Zaninetti R, Del Grosso E, Genazzani AA, Grosa G.

J Pharm Biomed Anal. 2013 May 5;78-79:233-42. doi: 10.1016/j.jpba.2013.02.030. Epub 2013 Feb 27.

PMID:
23501444
24.

Erythrocyte glutathione transferase: a novel biomarker to check environmental pollution hazardous for humans.

Fabrini R, Bocedi A, Del Grosso E, Morici L, Federici G, Palleschi A, Ricci G.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):71-5. doi: 10.1016/j.bbrc.2012.08.037. Epub 2012 Aug 14.

PMID:
22910412
25.

In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry.

Aprile S, Del Grosso E, Grosa G.

J Mass Spectrom. 2012 Jun;47(6):737-50. doi: 10.1002/jms.3011.

PMID:
22707166
26.

The metabolic fate of isocombretastatin A-4 in human liver microsomes: identification, synthesis and biological evaluation of metabolites.

Soussi MA, Aprile S, Messaoudi S, Provot O, Del Grosso E, Bignon J, Dubois J, Brion JD, Grosa G, Alami M.

ChemMedChem. 2011 Oct 4;6(10):1781-8. doi: 10.1002/cmdc.201100193. Epub 2011 Jul 11. No abstract available.

PMID:
21748852
27.

In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite.

Aprile S, Del Grosso E, Grosa G.

Xenobiotica. 2011 Mar;41(3):212-25. doi: 10.3109/00498254.2010.532887. Epub 2010 Nov 18.

PMID:
21087117
28.

Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.

Aprile S, Del Grosso E, Grosa G.

Drug Metab Dispos. 2010 Jul;38(7):1141-6. doi: 10.1124/dmd.109.031435. Epub 2010 Apr 7.

PMID:
20375181
29.

In vitro and in vivo phase II metabolism of combretastatin A-4: evidence for the formation of a sulphate conjugate metabolite.

Aprile S, Del Grosso E, Grosa G.

Xenobiotica. 2009 Feb;39(2):148-61. doi: 10.1080/00498250802566976.

PMID:
19255941
30.

Solution-phase parallel synthesis and biological evaluation of combretatriazoles.

Cafici L, Pirali T, Condorelli F, Del Grosso E, Massarotti A, Sorba G, Canonico PL, Tron GC, Genazzani AA.

J Comb Chem. 2008 Sep-Oct;10(5):732-40. doi: 10.1021/cc800090d. Epub 2008 Aug 6.

PMID:
18681482
31.

In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes.

Aprile S, Del Grosso E, Tron GC, Grosa G.

Drug Metab Dispos. 2007 Dec;35(12):2252-61. Epub 2007 Sep 21.

PMID:
17890446
32.

The furoxan system: design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasodilating activities.

Del Grosso E, Boschi D, Lazzarato L, Cena C, Di Stilo A, Fruttero R, Moro S, Gasco A.

Chem Biodivers. 2005 Jul;2(7):886-900.

PMID:
17193179
33.

Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup.

Grosa G, Del Grosso E, Russo R, Allegrone G.

J Pharm Biomed Anal. 2006 Jun 7;41(3):798-803. Epub 2006 Feb 23.

PMID:
16497471
34.

Rapid synthesis of triazole-modified resveratrol analogues via click chemistry.

Pagliai F, Pirali T, Del Grosso E, Di Brisco R, Tron GC, Sorba G, Genazzani AA.

J Med Chem. 2006 Jan 26;49(2):467-70.

PMID:
16420033
35.

LC-ESI-MS/MS characterization of strophanthin-K.

Grosa G, Allegrone G, Del Grosso E.

J Pharm Biomed Anal. 2005 Jun 1;38(1):79-86. Epub 2005 Jan 19.

PMID:
15907623
36.

Synthesis and cytotoxic evaluation of combretafurazans.

Tron GC, Pagliai F, Del Grosso E, Genazzani AA, Sorba G.

J Med Chem. 2005 May 5;48(9):3260-8.

PMID:
15857132
37.

Polycyclic compounds from aminopolyols and alpha-dicarbonyls: structure and application in the synthesis of exoditopic ligands.

Giovenzana GB, Palmisano G, Del Grosso E, Giovannelli L, Penoni A, Pilati T.

Org Biomol Chem. 2005 Apr 21;3(8):1489-94. Epub 2005 Mar 15.

PMID:
15827646
38.

Balance between autocrine interleukin-1beta and caspases defines life versus death of polymorphonuclear cells.

Bossù P, del Grosso E, Cesaroni MP, Maurizi G, Balestro N, Stoppacciaro A, del Giudice E, Ruggiero P, Boraschi D.

Eur Cytokine Netw. 2001 Mar;12(1):177-86.

39.

Inhibitory activity of IL-1 receptor antagonist depends on the balance between binding capacity for IL-1 receptor type 1 and IL-1 receptor type II.

Ruggiero P, Bossù P, Macchia G, Del Grosso E, Sabbatini V, Bertini R, Colagrande A, Bizzarri C, Maurizi G, Di Cioccio V, D'Andrea G, Di Giulio A, Frigerio F, Grifantini R, Grandi G, Tagliabue A, Boraschi D.

J Immunol. 1997 Apr 15;158(8):3881-7.

PMID:
9103457
40.

Involvement of an arachidonic-acid-dependent pathway in the interferon-beta-mediated expression of C202 gene in Ehrlich-ascites-tumor cells.

Toniato E, Flati V, Cifone MG, Del Grosso E, Roncaioli P, Cilenti L, Tessitore A, Lista F, Frati L, Gulino A, Martinotti S.

Eur J Biochem. 1996 Jan 15;235(1-2):91-6.

41.

Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains.

Boraschi D, Bossù P, Ruggiero P, Tagliabue A, Bertini R, Macchia G, Gasbarro C, Pellegrini L, Melillo G, Ulisse E, Visconti U, Bizzarri C, Del Grosso E, Mackay AR, Frascotti G, Frigerio F, Grifantini R, Grandi G.

J Immunol. 1995 Nov 15;155(10):4719-25.

PMID:
7594472
42.

Laparoscopic cholecystectomy: imaging of complications and normal postoperative CT appearance.

Moran J, Del Grosso E, Wills JS, Hagy JA, Baker R.

Abdom Imaging. 1994 Mar-Apr;19(2):143-6.

PMID:
8199546
43.

Involvement of phospholipase A2 activation and arachidonic acid metabolism in the cytotoxic functions of rat NK cells.

Cifone MG, Botti D, Festuccia C, Napolitano T, del Grosso E, Cavallo G, Chessa MA, Santoni A.

Cell Immunol. 1993 May;148(2):247-58.

PMID:
8388321
44.

Preferential involvement of a phospholipase A2-dependent pathway in CD69-mediated platelet activation.

Testi R, Pulcinelli FM, Cifone MG, Botti D, Del Grosso E, Riondino S, Frati L, Gazzaniga PP, Santoni A.

J Immunol. 1992 May 1;148(9):2867-71.

PMID:
1315360
45.

A possible plasma membrane particle containing malic enzyme activity.

Pupillo P, Del Grosso E.

Planta. 1981 May;151(6):506-11. doi: 10.1007/BF00387427.

PMID:
24302201
46.

The substrate specificity of pantethinase.

Duprè S, Rosei MA, Bellussi L, Del Grosso E, Cavallini D.

Eur J Biochem. 1973 Dec 3;40(1):103-7. No abstract available.

47.

The enzymatic breakdown of pantethine to pantothenic acid and cystamine.

Duprè S, Graziani MT, Rosei MA, Fabi A, Del Grosso E.

Eur J Biochem. 1970 Nov;16(3):571-8. No abstract available.

48.

Molecular weight of native and dissociated cysteamine oxygenase.

Cavallini D, Cannella C, Federici G, Duprè S, Fiori A, Del Grosso E.

Eur J Biochem. 1970 Nov;16(3):537-40. No abstract available.

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