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Items: 1 to 50 of 260

1.

PlatformTM, a standards-based data custodianship platform for translational medicine research.

Emam I, Elyasigomari V, Matthews A, Pavlidis S, Rocca-Serra P, Guitton F, Verbeeck D, Grainger L, Borgogni E, Del Giudice G, Saqi M, Houston P, Guo Y.

Sci Data. 2019 Aug 13;6(1):149. doi: 10.1038/s41597-019-0156-9.

2.

Identification of potential biomarkers of vaccine inflammation in mice.

McKay PF, Cizmeci D, Aldon Y, Maertzdorf J, Weiner J, Kaufmann SH, Lewis DJ, van den Berg RA, Del Giudice G, Shattock RJ.

Elife. 2019 May 14;8. pii: e46149. doi: 10.7554/eLife.46149.

3.

Adult vaccination as part of a healthy lifestyle: moving from medical intervention to health promotion.

Doherty TM, Del Giudice G, Maggi S.

Ann Med. 2019 Mar;51(2):128-140. doi: 10.1080/07853890.2019.1588470. Epub 2019 Apr 26.

PMID:
31025882
4.

Inhibiting neuraminidase can make the difference.

Rappuoli R, Del Giudice G.

J Exp Med. 2019 Feb 4;216(2):251-252. doi: 10.1084/jem.20182245. Epub 2019 Jan 25.

5.

Short-term and mid-term solutions for influenza vaccines.

Hanon E, Van der Most R, Del Giudice G, Rappuoli R.

Lancet Infect Dis. 2018 Aug;18(8):832-833. doi: 10.1016/S1473-3099(18)30404-3. No abstract available.

PMID:
30064669
6.

Intra-seasonal antibody repertoire analysis of a subject immunized with an MF59®-adjuvanted pandemic 2009 H1N1 vaccine.

Ferdman J, Palladino G, Liao HX, Moody MA, Kepler TB, Del Giudice G, Dormitzer PR, Harrison SC, Settembre EC, Suphaphiphat P.

Vaccine. 2018 Aug 23;36(35):5325-5332. doi: 10.1016/j.vaccine.2018.06.054. Epub 2018 Jul 25.

7.

Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study.

Malfertheiner P, Selgrad M, Wex T, Romi B, Borgogni E, Spensieri F, Zedda L, Ruggiero P, Pancotto L, Censini S, Palla E, Kanesa-Thasan N, Scharschmidt B, Rappuoli R, Graham DY, Schiavetti F, Del Giudice G.

Lancet Gastroenterol Hepatol. 2018 Oct;3(10):698-707. doi: 10.1016/S2468-1253(18)30125-0. Epub 2018 Jul 2.

PMID:
30042064
8.

Vaccination programs for older adults in an era of demographic change.

Doherty TM, Connolly MP, Del Giudice G, Flamaing J, Goronzy JJ, Grubeck-Loebenstein B, Lambert PH, Maggi S, McElhaney JE, Nagai H, Schaffner W, Schmidt-Ott R, Walsh E, Di Pasquale A.

Eur Geriatr Med. 2018;9(3):289-300. doi: 10.1007/s41999-018-0040-8. Epub 2018 Mar 19. Review.

9.

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines.

Del Giudice G, Rappuoli R, Didierlaurent AM.

Semin Immunol. 2018 Oct;39:14-21. doi: 10.1016/j.smim.2018.05.001. Epub 2018 May 23. Review.

10.

Preliminary Porcine In Vivo Evaluation of a Telerobotic System for Transurethral Bladder Tumor Resection and Surveillance.

Sarli N, Del Giudice G, De S, Dietrich MS, Herrell SD, Simaan N.

J Endourol. 2018 Jun;32(6):516-522. doi: 10.1089/end.2018.0119.

11.

Age and Influenza-Specific Pre-Vaccination Antibodies Strongly Affect Influenza Vaccine Responses in the Icelandic Population whereas Disease and Medication Have Small Effects.

Olafsdottir TA, Alexandersson KF, Sveinbjornsson G, Lapini G, Palladino L, Montomoli E, Del Giudice G, Gudbjartsson DF, Jonsdottir I.

Front Immunol. 2018 Jan 8;8:1872. doi: 10.3389/fimmu.2017.01872. eCollection 2017.

12.

Challenges in adult vaccination.

de Gomensoro E, Del Giudice G, Doherty TM.

Ann Med. 2018 May;50(3):181-192. doi: 10.1080/07853890.2017.1417632. Epub 2018 Jan 16. Review.

PMID:
29338438
13.

Fighting against a protean enemy: immunosenescence, vaccines, and healthy aging.

Del Giudice G, Goronzy JJ, Grubeck-Loebenstein B, Lambert PH, Mrkvan T, Stoddard JJ, Doherty TM.

NPJ Aging Mech Dis. 2017 Dec 21;4:1. doi: 10.1038/s41514-017-0020-0. eCollection 2018.

14.

Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination.

Haks MC, Bottazzi B, Cecchinato V, De Gregorio C, Del Giudice G, Kaufmann SHE, Lanzavecchia A, Lewis DJM, Maertzdorf J, Mantovani A, Sallusto F, Sironi M, Uguccioni M, Ottenhoff THM.

Front Immunol. 2017 Nov 15;8:1563. doi: 10.3389/fimmu.2017.01563. eCollection 2017. Review.

15.

Spermatogenic dynamics of the spiny rat Kannabateomys amblyonyx (Wagner, 1845) (Rodentia, Echimyidae).

Siman VA, Godoy RSM, Dias FCR, Silva FA, Del Giudice GML, Gomes MLM, Matta SLP.

Anim Reprod Sci. 2017 Sep;184:36-43. doi: 10.1016/j.anireprosci.2017.06.011. Epub 2017 Jun 28.

PMID:
28693937
16.

Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.

Raymond DD, Stewart SM, Lee J, Ferdman J, Bajic G, Do KT, Ernandes MJ, Suphaphiphat P, Settembre EC, Dormitzer PR, Del Giudice G, Finco O, Kang TH, Ippolito GC, Georgiou G, Kepler TB, Haynes BF, Moody MA, Liao HX, Schmidt AG, Harrison SC.

Nat Med. 2016 Dec;22(12):1465-1469. doi: 10.1038/nm.4223. Epub 2016 Nov 7.

17.

Kinematic and experimental investigation of manual resection tools for transurethral bladder tumor resection.

Sarli N, Marien T, Mitchell CR, Del Giudice G, Dietrich MS, Herrell SD, Simaan N.

Int J Med Robot. 2017 Jun;13(2). doi: 10.1002/rcs.1757. Epub 2016 Oct 20.

18.

Early Rise of Blood T Follicular Helper Cell Subsets and Baseline Immunity as Predictors of Persisting Late Functional Antibody Responses to Vaccination in Humans.

Spensieri F, Siena E, Borgogni E, Zedda L, Cantisani R, Chiappini N, Schiavetti F, Rosa D, Castellino F, Montomoli E, Bodinham CL, Lewis DJ, Medini D, Bertholet S, Del Giudice G.

PLoS One. 2016 Jun 23;11(6):e0157066. doi: 10.1371/journal.pone.0157066. eCollection 2016.

19.

Multivariate probability distribution for sewer system vulnerability assessment under data-limited conditions.

Del Giudice G, Padulano R, Siciliano D.

Water Sci Technol. 2016;73(4):751-60. doi: 10.2166/wst.2015.546.

PMID:
26901717
20.

Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood.

Nakaya HI, Clutterbuck E, Kazmin D, Wang L, Cortese M, Bosinger SE, Patel NB, Zak DE, Aderem A, Dong T, Del Giudice G, Rappuoli R, Cerundolo V, Pollard AJ, Pulendran B, Siegrist CA.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1853-8. doi: 10.1073/pnas.1519690113. Epub 2016 Jan 11.

21.

Influence of Statins on Influenza Vaccine Response in Elderly Individuals.

Black S, Nicolay U, Del Giudice G, Rappuoli R.

J Infect Dis. 2016 Apr 15;213(8):1224-8. doi: 10.1093/infdis/jiv456. Epub 2015 Oct 28.

PMID:
26516142
22.

Lung and Nodal Involvement in Nontuberculous Mycobacterial Disease: PET/CT Role.

Del Giudice G, Bianco A, Cennamo A, Santoro G, Bifulco M, Marzo C, Mazzarella G.

Biomed Res Int. 2015;2015:353202. doi: 10.1155/2015/353202. Epub 2015 May 28.

23.

B Cells and Functional Antibody Responses to Combat Influenza.

Lofano G, Kumar A, Finco O, Del Giudice G, Bertholet S.

Front Immunol. 2015 Jun 30;6:336. doi: 10.3389/fimmu.2015.00336. eCollection 2015. Review.

24.

Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro.

Chiappini N, Cantisani R, Pancotto L, Ruggiero P, Rosa D, Manetti A, Romano A, Montagnani F, Bertholet S, Castellino F, Del Giudice G.

PLoS One. 2015 Jun 12;10(6):e0129879. doi: 10.1371/journal.pone.0129879. eCollection 2015.

25.

MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life.

Mastelic Gavillet B, Eberhardt CS, Auderset F, Castellino F, Seubert A, Tregoning JS, Lambert PH, de Gregorio E, Del Giudice G, Siegrist CA.

J Immunol. 2015 May 15;194(10):4836-45. doi: 10.4049/jimmunol.1402071. Epub 2015 Apr 13.

26.

mTOR inhibition improves immune function in the elderly.

Mannick JB, Del Giudice G, Lattanzi M, Valiante NM, Praestgaard J, Huang B, Lonetto MA, Maecker HT, Kovarik J, Carson S, Glass DJ, Klickstein LB.

Sci Transl Med. 2014 Dec 24;6(268):268ra179. doi: 10.1126/scitranslmed.3009892.

PMID:
25540326
27.

Vaccines for the elderly.

Del Giudice G, Weinberger B, Grubeck-Loebenstein B.

Gerontology. 2015;61(3):203-10. doi: 10.1159/000366162. Epub 2014 Nov 13. Review.

PMID:
25402229
28.

Optimized fluorescent labeling to identify memory B cells specific for Neisseria meningitidis serogroup B vaccine antigens ex vivo.

Nair N, Buti L, Faenzi E, Buricchi F, Nuti S, Sammicheli C, Tavarini S, Popp MW, Ploegh H, Berti F, Pizza M, Castellino F, Finco O, Rappuoli R, Del Giudice G, Galli G, Bardelli M.

Immun Inflamm Dis. 2013 Oct;1(1):3-13. doi: 10.1002/iid3.3. Epub 2013 Oct 30.

29.

Vaccines, new opportunities for a new society.

Rappuoli R, Pizza M, Del Giudice G, De Gregorio E.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12288-93. doi: 10.1073/pnas.1402981111. Epub 2014 Aug 18. Review.

30.

Inactivated and adjuvanted influenza vaccines.

Del Giudice G, Rappuoli R.

Curr Top Microbiol Immunol. 2015;386:151-80. doi: 10.1007/82_2014_406. Review.

PMID:
25038938
31.

Dissecting the immune response to MF59-adjuvanted and nonadjuvanted seasonal influenza vaccines in children less than three years of age.

Zedda L, Forleo-Neto E, Vertruyen A, Raes M, Marchant A, Jansen W, Clouting H, Arora A, Beatty ME, Galli G, Del Giudice G, Castellino F.

Pediatr Infect Dis J. 2015 Jan;34(1):73-8. doi: 10.1097/INF.0000000000000465.

PMID:
25037034
32.

Heterologous prime-boost vaccination with MF59-adjuvanted H5 vaccines promotes antibody affinity maturation towards the hemagglutinin HA1 domain and broad H5N1 cross-clade neutralization.

Khurana S, Coyle EM, Dimitrova M, Castellino F, Nicholson K, Del Giudice G, Golding H.

PLoS One. 2014 Apr 22;9(4):e95496. doi: 10.1371/journal.pone.0095496. eCollection 2014.

33.

A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration.

Della Cioppa G, Nicolay U, Lindert K, Leroux-Roels G, Clement F, Castellino F, Galli C, Groth N, Levin Y, Del Giudice G.

Hum Vaccin Immunother. 2014;10(6):1701-10. doi: 10.4161/hv.28618. Epub 2014 Apr 14.

34.

Challenges and responses in human vaccine development.

Kaufmann SH, McElrath MJ, Lewis DJ, Del Giudice G.

Curr Opin Immunol. 2014 Jun;28:18-26. doi: 10.1016/j.coi.2014.01.009. Epub 2014 Feb 19. Review.

35.

Predictive markers of safety and immunogenicity of adjuvanted vaccines.

Mastelic B, Garçon N, Del Giudice G, Golding H, Gruber M, Neels P, Fritzell B.

Biologicals. 2013 Nov;41(6):458-68. doi: 10.1016/j.biologicals.2013.08.006. Epub 2013 Sep 23.

PMID:
24071553
36.

Pneumococcal polysaccharide abrogates conjugate-induced germinal center reaction and depletes antibody secreting cell pool, causing hyporesponsiveness.

Bjarnarson SP, Benonisson H, Del Giudice G, Jonsdottir I.

PLoS One. 2013 Sep 12;8(9):e72588. doi: 10.1371/journal.pone.0072588. eCollection 2013.

37.

Ex vivo analysis of human memory B lymphocytes specific for A and B influenza hemagglutinin by polychromatic flow-cytometry.

Bardelli M, Alleri L, Angiolini F, Buricchi F, Tavarini S, Sammicheli C, Nuti S, Degl'Innocenti E, Isnardi I, Fragapane E, Del Giudice G, Castellino F, Galli G.

PLoS One. 2013 Aug 15;8(8):e70620. doi: 10.1371/journal.pone.0070620. eCollection 2013.

38.

Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines.

Tontini M, Berti F, Romano MR, Proietti D, Zambonelli C, Bottomley MJ, De Gregorio E, Del Giudice G, Rappuoli R, Costantino P; Study Group, Brogioni G, Balocchi C, Biancucci M, Malito E.

Vaccine. 2013 Oct 1;31(42):4827-33. doi: 10.1016/j.vaccine.2013.07.078. Epub 2013 Aug 17.

PMID:
23965218
39.

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses.

Spensieri F, Borgogni E, Zedda L, Bardelli M, Buricchi F, Volpini G, Fragapane E, Tavarini S, Finco O, Rappuoli R, Del Giudice G, Galli G, Castellino F.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14330-5. doi: 10.1073/pnas.1311998110. Epub 2013 Aug 12.

40.

Expression of the Streptococcus pneumoniae pilus-1 undergoes on and off switching during colonization in mice.

Pancotto L, De Angelis G, Bizzarri E, Barocchi MA, Del Giudice G, Moschioni M, Ruggiero P.

Sci Rep. 2013;3:2040. doi: 10.1038/srep02040.

41.

The gracefully aging immune system.

Boraschi D, Aguado MT, Dutel C, Goronzy J, Louis J, Grubeck-Loebenstein B, Rappuoli R, Del Giudice G.

Sci Transl Med. 2013 May 15;5(185):185ps8. doi: 10.1126/scitranslmed.3005624. Review.

PMID:
23677590
42.

Is the adjuvant solely to blame?

Tsai T, Del Giudice G, Crucitti A, Weil J, Narasimhan V.

BMJ. 2013 Apr 17;346:f2375. doi: 10.1136/bmj.f2375. No abstract available.

PMID:
23596217
43.

Impact of preexisting memory to seasonal A/H1N1 influenza virus on the immune response following vaccination against avian A/H5N1 virus.

Buricchi F, Bardelli M, Malzone C, Capecchi B, Nicolay U, Fragapane E, Castellino F, Del Giudice G, Galli G, Finco O.

Eur J Immunol. 2013 Mar;43(3):641-8. doi: 10.1002/eji.201242563. Epub 2013 Jan 24.

44.

Aflunov®: a vaccine tailored for pre-pandemic and pandemic approaches against influenza.

Del Giudice G, Fragapane E, Della Cioppa G, Rappuoli R.

Expert Opin Biol Ther. 2013 Jan;13(1):121-35. doi: 10.1517/14712598.2013.748030. Epub 2012 Nov 29. Review.

PMID:
23189937
45.

The adjuvant LT-K63 can restore delayed maturation of follicular dendritic cells and poor persistence of both protein- and polysaccharide-specific antibody-secreting cells in neonatal mice.

Bjarnarson SP, Adarna BC, Benonisson H, Del Giudice G, Jonsdottir I.

J Immunol. 2012 Aug 1;189(3):1265-73. doi: 10.4049/jimmunol.1200761. Epub 2012 Jul 2.

46.

Implant and long-term evaluation of atrial signal amplification in a single-lead ICD.

Stazi F, Mampieri M, Cardinale M, Laudadio MT, Gargaro A, Del Giudice GB.

Pacing Clin Electrophysiol. 2012 Sep;35(9):1119-25. doi: 10.1111/j.1540-8159.2012.03452.x. Epub 2012 Jun 26.

PMID:
22734815
47.

One dose of an MF59-adjuvanted pandemic A/H1N1 vaccine recruits pre-existing immune memory and induces the rapid rise of neutralizing antibodies.

Faenzi E, Zedda L, Bardelli M, Spensieri F, Borgogni E, Volpini G, Buricchi F, Pasini FL, Capecchi PL, Montanaro F, Belli R, Lattanzi M, Piccirella S, Montomoli E, Ahmed SS, Rappuoli R, Del Giudice G, Finco O, Castellino F, Galli G.

Vaccine. 2012 Jun 8;30(27):4086-94. doi: 10.1016/j.vaccine.2012.04.020. Epub 2012 Apr 19.

PMID:
22521851
48.

A caprine herpesvirus 1 vaccine adjuvanted with MF59™ protects against vaginal infection and interferes with the establishment of latency in goats.

Marinaro M, Rezza G, Del Giudice G, Colao V, Tarsitano E, Camero M, Losurdo M, Buonavoglia C, Tempesta M.

PLoS One. 2012;7(4):e34913. doi: 10.1371/journal.pone.0034913. Epub 2012 Apr 12.

49.

Effects of nonylphenol on vitellogenin synthesis in adult males of the spotted ray Torpedo marmorata.

Del Giudice G, Prisco M, Agnese M, Verderame M, Rosati L, Limatola E, Andreuccetti P.

J Fish Biol. 2012 Apr;80(5):2112-21. doi: 10.1111/j.1095-8649.2011.03172.x. Epub 2012 Jan 5.

PMID:
22497418
50.

Superior immunogenicity of seasonal influenza vaccines containing full dose of MF59 (®) adjuvant: results from a dose-finding clinical trial in older adults.

Della Cioppa G, Nicolay U, Lindert K, Leroux-Roels G, Clement F, Castellino F, Galli G, Groth N, Del Giudice G.

Hum Vaccin Immunother. 2012 Feb;8(2):216-27. doi: 10.4161/hv.18445. Epub 2012 Feb 1.

PMID:
22426371

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