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Items: 1 to 50 of 149

1.

Optical Control of Small Molecule-Induced Protein Degradation.

Naro Y, Darrah K, Deiters A.

J Am Chem Soc. 2020 Jan 23. doi: 10.1021/jacs.9b12718. [Epub ahead of print]

PMID:
31927988
2.

Enzyme Allostery: Now Controllable by Light.

Courtney TM, Deiters A.

Cell Chem Biol. 2019 Nov 21;26(11):1481-1483. doi: 10.1016/j.chembiol.2019.11.001.

PMID:
31756329
3.

Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation.

Wesalo JS, Luo J, Morihiro K, Liu J, Deiters A.

Chembiochem. 2020 Jan 15;21(1-2):141-148. doi: 10.1002/cbic.201900464. Epub 2019 Oct 30.

PMID:
31664790
4.

Optical control of protein phosphatase function.

Courtney TM, Deiters A.

Nat Commun. 2019 Sep 26;10(1):4384. doi: 10.1038/s41467-019-12260-z.

5.

Synthesis and application of light-switchable arylazopyrazole rapamycin analogs.

Courtney TM, Horst TJ, Hankinson CP, Deiters A.

Org Biomol Chem. 2019 Sep 28;17(36):8348-8353. doi: 10.1039/c9ob01719d. Epub 2019 Aug 30.

PMID:
31469140
6.

Preface.

Deiters A.

Methods Enzymol. 2019;624:xiii-xv. doi: 10.1016/S0076-6879(19)30337-4. No abstract available.

PMID:
31370938
7.

Combinatorial control of gene function with wavelength-selective caged morpholinos.

Pattanayak S, Vázquez-Maldonado LA, Deiters A, Chen JK.

Methods Enzymol. 2019;624:69-88. doi: 10.1016/bs.mie.2019.04.007. Epub 2019 Apr 25.

PMID:
31370936
8.

Light-activation of Cre recombinase in zebrafish embryos through genetic code expansion.

Brown W, Deiters A.

Methods Enzymol. 2019;624:265-281. doi: 10.1016/bs.mie.2019.04.004. Epub 2019 Apr 30.

PMID:
31370934
9.

Small molecule inhibition of microRNA-21 expression reduces cell viability and microtumor formation.

Ankenbruck N, Kumbhare R, Naro Y, Thomas M, Gardner L, Emanuelson C, Deiters A.

Bioorg Med Chem. 2019 Aug 15;27(16):3735-3743. doi: 10.1016/j.bmc.2019.05.044. Epub 2019 May 29.

PMID:
31262664
10.

Development of photolabile protecting groups and their application to the optochemical control of cell signaling.

Bardhan A, Deiters A.

Curr Opin Struct Biol. 2019 Aug;57:164-175. doi: 10.1016/j.sbi.2019.03.028. Epub 2019 May 25. Review.

PMID:
31132552
11.

Use of the Alvarado Score in Elderly Patients with Complicated and Uncomplicated Appendicitis.

Deiters A, Drozd A, Parikh P, Markert R, Shim JK.

Am Surg. 2019 Apr 1;85(4):397-402.

PMID:
31043201
12.

Aryl Azides as Phosphine-Activated Switches for Small Molecule Function.

Lukasak B, Morihiro K, Deiters A.

Sci Rep. 2019 Feb 6;9(1):1470. doi: 10.1038/s41598-018-37023-6.

13.

A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product.

Goulden BD, Pacheco J, Dull A, Zewe JP, Deiters A, Hammond GRV.

J Cell Biol. 2019 Mar 4;218(3):1066-1079. doi: 10.1083/jcb.201809026. Epub 2018 Dec 27.

14.

Allosteres to regulate neurotransmitter sulfonation.

Darrah K, Wang T, Cook I, Cacace M, Deiters A, Leyh TS.

J Biol Chem. 2019 Feb 15;294(7):2293-2301. doi: 10.1074/jbc.RA118.006511. Epub 2018 Dec 13.

PMID:
30545938
15.

Computational design of chemogenetic and optogenetic split proteins.

Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, Deiters A, Der CJ, Hahn KM, Dokholyan NV.

Nat Commun. 2018 Oct 2;9(1):4042. doi: 10.1038/s41467-018-06531-4.

16.

Reversible and Tunable Photoswitching of Protein Function through Genetic Encoding of Azobenzene Amino Acids in Mammalian Cells.

Luo J, Samanta S, Convertino M, Dokholyan NV, Deiters A.

Chembiochem. 2018 Oct 18;19(20):2178-2185. doi: 10.1002/cbic.201800226. Epub 2018 Oct 2.

17.

Potent and Readily Accessible Bistramide A Analogues through Diverted Total Synthesis.

Hanna RD, Naro Y, Deiters A, Floreancig PE.

Chemistry. 2018 Nov 2;24(61):16271-16275. doi: 10.1002/chem.201804417. Epub 2018 Oct 9.

PMID:
30175480
18.

Genetic Code Expansion in Animals.

Brown W, Liu J, Deiters A.

ACS Chem Biol. 2018 Sep 21;13(9):2375-2386. doi: 10.1021/acschembio.8b00520. Epub 2018 Sep 5. Review.

PMID:
30125487
19.

Recent advances in the optical control of protein function through genetic code expansion.

Courtney T, Deiters A.

Curr Opin Chem Biol. 2018 Oct;46:99-107. doi: 10.1016/j.cbpa.2018.07.011. Epub 2018 Jul 26. Review.

PMID:
30056281
20.

Small Molecule Inhibition of MicroRNA miR-21 Rescues Chemosensitivity of Renal-Cell Carcinoma to Topotecan.

Naro Y, Ankenbruck N, Thomas M, Tivon Y, Connelly CM, Gardner L, Deiters A.

J Med Chem. 2018 Jul 26;61(14):5900-5909. doi: 10.1021/acs.jmedchem.7b01891. Epub 2018 Jul 11.

PMID:
29993250
21.

Special Issue on Optochemical and Optogenetic Control of Cellular Processes.

Deiters A.

Chembiochem. 2018 Jun 18;19(12):1198-1200. doi: 10.1002/cbic.201800277. Epub 2018 Jun 6.

PMID:
29873157
22.

Cell-Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code.

Brown W, Liu J, Tsang M, Deiters A.

Chembiochem. 2018 Jun 18;19(12):1244-1249. doi: 10.1002/cbic.201800040. Epub 2018 May 18.

23.

Optochemical Control of Protein Localization and Activity within Cell-like Compartments.

Caldwell RM, Bermudez JG, Thai D, Aonbangkhen C, Schuster BS, Courtney T, Deiters A, Hammer DA, Chenoweth DM, Good MC.

Biochemistry. 2018 May 8;57(18):2590-2596. doi: 10.1021/acs.biochem.8b00131. Epub 2018 Apr 19.

PMID:
29671583
24.

Small Molecule Release and Activation through DNA Computing.

Morihiro K, Ankenbruck N, Lukasak B, Deiters A.

J Am Chem Soc. 2017 Oct 4;139(39):13909-13915. doi: 10.1021/jacs.7b07831. Epub 2017 Sep 25.

PMID:
28945369
25.

Genetic Code Expansion in Zebrafish Embryos and Its Application to Optical Control of Cell Signaling.

Liu J, Hemphill J, Samanta S, Tsang M, Deiters A.

J Am Chem Soc. 2017 Jul 12;139(27):9100-9103. doi: 10.1021/jacs.7b02145. Epub 2017 Jun 28.

26.

Genetic Encoding of Photocaged Tyrosines with Improved Light-Activation Properties for the Optical Control of Protease Function.

Luo J, Torres-Kolbus J, Liu J, Deiters A.

Chembiochem. 2017 Jul 18;18(14):1442-1447. doi: 10.1002/cbic.201700147. Epub 2017 Jun 13.

PMID:
28608946
27.

Optochemical Control of Biological Processes in Cells and Animals.

Ankenbruck N, Courtney T, Naro Y, Deiters A.

Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2768-2798. doi: 10.1002/anie.201700171. Epub 2018 Feb 1. Review.

28.

Optical Control of DNA Helicase Function through Genetic Code Expansion.

Luo J, Kong M, Liu L, Samanta S, Van Houten B, Deiters A.

Chembiochem. 2017 Mar 2;18(5):466-469. doi: 10.1002/cbic.201600624. Epub 2017 Jan 25.

29.

Small-molecule control of protein function through Staudinger reduction.

Luo J, Liu Q, Morihiro K, Deiters A.

Nat Chem. 2016 Nov;8(11):1027-1034. doi: 10.1038/nchem.2573. Epub 2016 Jul 25.

30.

Alcohol, Aldehyde, and Ketone Liberation and Intracellular Cargo Release through Peroxide-Mediated α-Boryl Ether Fragmentation.

Hanna RD, Naro Y, Deiters A, Floreancig PE.

J Am Chem Soc. 2016 Oct 12;138(40):13353-13360. Epub 2016 Sep 30.

PMID:
27636404
31.

Genetically encoded optical activation of DNA recombination in human cells.

Luo J, Arbely E, Zhang J, Chou C, Uprety R, Chin JW, Deiters A.

Chem Commun (Camb). 2016 Jun 30;52(55):8529-32. doi: 10.1039/c6cc03934k.

32.

A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes.

Wang WW, Zeng Y, Wu B, Deiters A, Liu WR.

ACS Chem Biol. 2016 Jul 15;11(7):1973-81. doi: 10.1021/acschembio.6b00243. Epub 2016 May 17.

33.

Conditional Control of CRISPR/Cas9 Function.

Zhou W, Deiters A.

Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5394-9. doi: 10.1002/anie.201511441. Epub 2016 Mar 21. Review.

PMID:
26996256
34.

Genetic Code Expansion of Mammalian Cells with Unnatural Amino Acids.

Brown KA, Deiters A.

Curr Protoc Chem Biol. 2015 Sep 1;7(3):187-199. doi: 10.1002/9780470559277.ch150038.

PMID:
26331526
35.

Aryl amide small-molecule inhibitors of microRNA miR-21 function.

Naro Y, Thomas M, Stephens MD, Connelly CM, Deiters A.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4793-4796. doi: 10.1016/j.bmcl.2015.07.016. Epub 2015 Jul 17.

PMID:
26220158
36.

Optically Triggered Immune Response through Photocaged Oligonucleotides.

Govan JM, Young DD, Lively MO, Deiters A.

Tetrahedron Lett. 2015 Jun 3;56(23):3639-3642.

37.

Optical Control of CRISPR/Cas9 Gene Editing.

Hemphill J, Borchardt EK, Brown K, Asokan A, Deiters A.

J Am Chem Soc. 2015 May 6;137(17):5642-5. doi: 10.1021/ja512664v. Epub 2015 Apr 23.

38.

Engineering a bacterial tape recorder.

Prokup A, Deiters A.

Chembiochem. 2015 May 4;16(7):1027-9. doi: 10.1002/cbic.201500061. Epub 2015 Mar 27.

PMID:
25821162
39.

Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides.

Hemphill J, Liu Q, Uprety R, Samanta S, Tsang M, Juliano RL, Deiters A.

J Am Chem Soc. 2015 Mar 18;137(10):3656-62. doi: 10.1021/jacs.5b00580. Epub 2015 Mar 3.

40.

Light-cleavable rapamycin dimer as an optical trigger for protein dimerization.

Brown KA, Zou Y, Shirvanyants D, Zhang J, Samanta S, Mantravadi PK, Dokholyan NV, Deiters A.

Chem Commun (Camb). 2015 Apr 4;51(26):5702-5. doi: 10.1039/c4cc09442e.

PMID:
25716548
41.

Optically Controlled Signal Amplification for DNA Computation.

Prokup A, Hemphill J, Liu Q, Deiters A.

ACS Synth Biol. 2015 Oct 16;4(10):1064-9. doi: 10.1021/sb500279w. Epub 2015 Jan 26.

PMID:
25621535
42.

Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides.

Chukkapalli V, Berger KL, Kelly SM, Thomas M, Deiters A, Randall G.

Virology. 2015 Feb;476:168-179. doi: 10.1016/j.virol.2014.12.018. Epub 2014 Dec 26.

43.

Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation.

Luo J, Uprety R, Naro Y, Chou C, Nguyen DP, Chin JW, Deiters A.

J Am Chem Soc. 2014 Nov 5;136(44):15551-8. doi: 10.1021/ja5055862. Epub 2014 Oct 23.

44.

Interfacing synthetic DNA logic operations with protein outputs.

Prokup A, Deiters A.

Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13192-5. doi: 10.1002/anie.201406892. Epub 2014 Oct 5.

PMID:
25283524
45.

Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.

Lee YJ, Kurra Y, Yang Y, Torres-Kolbus J, Deiters A, Liu WR.

Chem Commun (Camb). 2014 Nov 7;50(86):13085-8. doi: 10.1039/c4cc06435f. Erratum in: Chem Commun (Camb). 2014 Nov 11;50(87):13396.

46.

Synthesis of non-linear protein dimers through a genetically encoded Thiol-ene reaction.

Torres-Kolbus J, Chou C, Liu J, Deiters A.

PLoS One. 2014 Sep 2;9(9):e105467. doi: 10.1371/journal.pone.0105467. eCollection 2014.

47.

Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

Kurra Y, Odoi KA, Lee YJ, Yang Y, Lu T, Wheeler SE, Torres-Kolbus J, Deiters A, Liu WR.

Bioconjug Chem. 2014 Sep 17;25(9):1730-8. doi: 10.1021/bc500361d. Epub 2014 Sep 4.

48.

Sequential gene silencing using wavelength-selective caged morpholino oligonucleotides.

Yamazoe S, Liu Q, McQuade LE, Deiters A, Chen JK.

Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10114-8. doi: 10.1002/anie.201405355. Epub 2014 Aug 1.

49.

Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells.

Uprety R, Luo J, Liu J, Naro Y, Samanta S, Deiters A.

Chembiochem. 2014 Aug 18;15(12):1793-9. doi: 10.1002/cbic.201400073. Epub 2014 Jun 27.

PMID:
24976145
50.

Thiourea-based fluorescent chemosensors for aqueous metal ion detection and cellular imaging.

Vonlanthen M, Connelly CM, Deiters A, Linden A, Finney NS.

J Org Chem. 2014 Jul 3;79(13):6054-60. doi: 10.1021/jo500710g. Epub 2014 Jun 24.

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