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Items: 38


Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons.

Hallinan GI, Vargas-Caballero M, West J, Deinhardt K.

J Neurosci. 2019 Nov 27;39(48):9623-9632. doi: 10.1523/JNEUROSCI.1590-19.2019. Epub 2019 Oct 28.


Proteomic Approaches to Dissect Neuronal Signalling Pathways.

Bowling HL, Nayak S, Deinhardt K.

Adv Exp Med Biol. 2019;1140:469-475. doi: 10.1007/978-3-030-15950-4_27. Review.


A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain.

Warming H, Pegasiou CM, Pitera AP, Kariis H, Houghton SD, Kurbatskaya K, Ahmed A, Grundy P, Vajramani G, Bulters D, Altafaj X, Deinhardt K, Vargas-Caballero M.

Mol Brain. 2019 Jul 4;12(1):64. doi: 10.1186/s13041-019-0485-9.


Pathogenic tau does not drive activation of the unfolded protein response.

Pitera AP, Asuni AA, O'Connor V, Deinhardt K.

J Biol Chem. 2019 Jun 21;294(25):9679-9688. doi: 10.1074/jbc.RA119.008263. Epub 2019 May 3.


Asymmetric confinement for defining outgrowth directionality.

Holloway PM, Hallinan GI, Hegde M, Lane SIR, Deinhardt K, West J.

Lab Chip. 2019 Apr 9;19(8):1484-1489. doi: 10.1039/c9lc00078j.


Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer's disease.

Sri S, Pegasiou CM, Cave CA, Hough K, Wood N, Gomez-Nicola D, Deinhardt K, Bannerman D, Perry VH, Vargas-Caballero M.

Acta Neuropathol Commun. 2019 Feb 22;7(1):25. doi: 10.1186/s40478-019-0670-1.


Minimalistic in vitro systems for investigating tau pathology.

Hallinan GI, Pitera AP, Patel P, West J, Deinhardt K.

J Neurosci Methods. 2019 May 1;319:69-76. doi: 10.1016/j.jneumeth.2018.09.032. Epub 2018 Sep 29. Review.


Mechano-sensitization of mammalian neuronal networks through expression of the bacterial large-conductance mechanosensitive ion channel.

Soloperto A, Boccaccio A, Contestabile A, Moroni M, Hallinan GI, Palazzolo G, Chad J, Deinhardt K, Carugo D, Difato F.

J Cell Sci. 2018 Mar 8;131(5). pii: jcs210393. doi: 10.1242/jcs.210393.


Modulation of nonsense mediated decay by rapamycin.

Martinez-Nunez RT, Wallace A, Coyne D, Jansson L, Rush M, Ennajdaoui H, Katzman S, Bailey J, Deinhardt K, Sanchez-Elsner T, Sanford JR.

Nucleic Acids Res. 2017 Apr 7;45(6):3448-3459. doi: 10.1093/nar/gkw1109.


Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.

Domènech-Estévez E, Baloui H, Meng X, Zhang Y, Deinhardt K, Dupree JL, Einheber S, Chrast R, Salzer JL.

J Neurosci. 2016 Apr 20;36(16):4506-21. doi: 10.1523/JNEUROSCI.3521-15.2016.


Stable isotope labeling by amino acids in cultured primary neurons.

Zhang G, Deinhardt K, Neubert TA.

Methods Mol Biol. 2014;1188:57-64. doi: 10.1007/978-1-4939-1142-4_5.


Investigating a novel protein using mass spectrometry: the example of tumor differentiation factor (TDF).

Woods AG, Sokolowska I, Deinhardt K, Darie CC.

Adv Exp Med Biol. 2014;806:509-23. doi: 10.1007/978-3-319-06068-2_25. Review.


Proteomic approaches to dissect neuronal signaling pathways.

Bowling HL, Deinhardt K.

Adv Exp Med Biol. 2014;806:499-508. doi: 10.1007/978-3-319-06068-2_24. Review.


Trk receptors.

Deinhardt K, Chao MV.

Handb Exp Pharmacol. 2014;220:103-19. doi: 10.1007/978-3-642-45106-5_5. Review.


Trkb signaling in pericytes is required for cardiac microvessel stabilization.

Anastasia A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, Trinh J, Parada L, Rafii S, Hempstead BL, Kermani P.

PLoS One. 2014 Jan 31;9(1):e87406. doi: 10.1371/journal.pone.0087406. eCollection 2014.


Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity.

Bowling H, Zhang G, Bhattacharya A, Pérez-Cuesta LM, Deinhardt K, Hoeffer CA, Neubert TA, Gan WB, Klann E, Chao MV.

Sci Signal. 2014 Jan 14;7(308):ra4. doi: 10.1126/scisignal.2004331.


Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction.

Anastasia A, Deinhardt K, Chao MV, Will NE, Irmady K, Lee FS, Hempstead BL, Bracken C.

Nat Commun. 2013;4:2490. doi: 10.1038/ncomms3490. Erratum in: Nat Commun. 2014;5:3564.


Identification of tumor differentiation factor (TDF) in select CNS neurons.

Woods AG, Sokolowska I, Deinhardt K, Sandu C, Darie CC.

Brain Struct Funct. 2014 Jul;219(4):1333-42. doi: 10.1007/s00429-013-0571-1. Epub 2013 May 17.


Shaping neurons: Long and short range effects of mature and proBDNF signalling upon neuronal structure.

Deinhardt K, Chao MV.

Neuropharmacology. 2014 Jan;76 Pt C:603-9. doi: 10.1016/j.neuropharm.2013.04.054. Epub 2013 May 7. Review.


Protein-protein interactions: switch from classical methods to proteomics and bioinformatics-based approaches.

Ngounou Wetie AG, Sokolowska I, Woods AG, Roy U, Deinhardt K, Darie CC.

Cell Mol Life Sci. 2014 Jan;71(2):205-28. doi: 10.1007/s00018-013-1333-1. Epub 2013 Apr 12. Review.


Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors.

Kaphzan H, Hernandez P, Jung JI, Cowansage KK, Deinhardt K, Chao MV, Abel T, Klann E.

Biol Psychiatry. 2012 Aug 1;72(3):182-90. doi: 10.1016/j.biopsych.2012.01.021. Epub 2012 Mar 3.


Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL.

Sci Signal. 2011 Dec 6;4(202):ra82. doi: 10.1126/scisignal.2002060.


Fine-tuning MAPK signaling in the brain: The role of MKP-1.

Jeanneteau F, Deinhardt K.

Commun Integr Biol. 2011 May;4(3):281-3. doi: 10.4161/cib.4.3.14766.


Identifying transient protein-protein interactions in EphB2 signaling by blue native PAGE and mass spectrometry.

Darie CC, Deinhardt K, Zhang G, Cardasis HS, Chao MV, Neubert TA.

Proteomics. 2011 Dec;11(23):4514-28. doi: 10.1002/pmic.201000819. Epub 2011 Oct 28.


Study of neurotrophin-3 signaling in primary cultured neurons using multiplex stable isotope labeling with amino acids in cell culture.

Zhang G, Deinhardt K, Chao MV, Neubert TA.

J Proteome Res. 2011 May 6;10(5):2546-54. doi: 10.1021/pr200016n. Epub 2011 Mar 28.


The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching.

Jeanneteau F, Deinhardt K, Miyoshi G, Bennett AM, Chao MV.

Nat Neurosci. 2010 Nov;13(11):1373-9. doi: 10.1038/nn.2655. Epub 2010 Oct 10.


A role for huntington disease protein in dendritic RNA granules.

Savas JN, Ma B, Deinhardt K, Culver BP, Restituito S, Wu L, Belasco JG, Chao MV, Tanese N.

J Biol Chem. 2010 Apr 23;285(17):13142-53. doi: 10.1074/jbc.M110.114561. Epub 2010 Feb 25.


Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons.

Ohka S, Sakai M, Bohnert S, Igarashi H, Deinhardt K, Schiavo G, Nomoto A.

J Virol. 2009 May;83(10):4995-5004. doi: 10.1128/JVI.02225-08. Epub 2009 Feb 25.


Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling.

Spellman DS, Deinhardt K, Darie CC, Chao MV, Neubert TA.

Mol Cell Proteomics. 2008 Jun;7(6):1067-76. doi: 10.1074/mcp.M700387-MCP200. Epub 2008 Feb 6.


Neurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport.

Deinhardt K, Reversi A, Berninghausen O, Hopkins CR, Schiavo G.

Traffic. 2007 Dec;8(12):1736-49. Epub 2007 Sep 26.


The phagocytic capacity of neurones.

Bowen S, Ateh DD, Deinhardt K, Bird MM, Price KM, Baker CS, Robson JC, Swash M, Shamsuddin W, Kawar S, El-Tawil T, Roos J, Hoyle A, Nickols CD, Knowles CH, Pullen AH, Luthert PJ, Weller RO, Hafezparast M, Franklin RJ, Revesz T, King RH, Berninghausen O, Fisher EM, Schiavo G, Martin JE.

Eur J Neurosci. 2007 May;25(10):2947-55.


Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality.

Müller JM, Deinhardt K, Rosewell I, Warren G, Shima DT.

Biochem Biophys Res Commun. 2007 Mar 9;354(2):459-65. Epub 2007 Jan 8.


An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis.

Ioannidou S, Deinhardt K, Miotla J, Bradley J, Cheung E, Samuelsson S, Ng YS, Shima DT.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16770-5. Epub 2006 Oct 30.


Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway.

Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C, Schiavo G.

Neuron. 2006 Oct 19;52(2):293-305.


Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1.

Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR, Schiavo G.

J Cell Biol. 2006 Jul 31;174(3):459-71.


Endocytosis and retrograde axonal traffic in motor neurons.

Deinhardt K, Schiavo G.

Biochem Soc Symp. 2005;(72):139-50. Review.


The journey of tetanus and botulinum neurotoxins in neurons.

Lalli G, Bohnert S, Deinhardt K, Verastegui C, Schiavo G.

Trends Microbiol. 2003 Sep;11(9):431-7. Review.


Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion.

Muller JM, Shorter J, Newman R, Deinhardt K, Sagiv Y, Elazar Z, Warren G, Shima DT.

J Cell Biol. 2002 Jun 24;157(7):1161-73. Epub 2002 Jun 17.

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