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Items: 20

1.

A novel RNA polymerase-binding protein that interacts with a sigma-factor docking site.

Wang Erickson AF, Deighan P, Chen S, Barrasso K, Garcia CP, Martínez-Lumbreras S, Alfano C, Krysztofinska EM, Thapaliya A, Camp AH, Isaacson RL, Hochschild A, Losick R.

Mol Microbiol. 2017 Aug;105(4):652-662. doi: 10.1111/mmi.13724. Epub 2017 Jun 19.

2.

An Amino Acid Substitution in RNA Polymerase That Inhibits the Utilization of an Alternative Sigma Factor.

Wang Erickson AF, Deighan P, Garcia CP, Weinzierl ROJ, Hochschild A, Losick R.

J Bacteriol. 2017 Jun 27;199(14). pii: e00277-17. doi: 10.1128/JB.00277-17. Print 2017 Jul 15.

3.

Precipitation SELEX: identification of DNA aptamers for calcium phosphate materials synthesis.

Baillargeon KR, Meserve K, Faulkner S, Watson S, Butts H, Deighan P, Gerdon AE.

Chem Commun (Camb). 2017 Jan 17;53(6):1092-1095. doi: 10.1039/c6cc08687j.

PMID:
28045140
4.

Nascent RNA length dictates opposing effects of NusA on antitermination.

Wells CD, Deighan P, Brigham M, Hochschild A.

Nucleic Acids Res. 2016 Jun 20;44(11):5378-89. doi: 10.1093/nar/gkw198. Epub 2016 Mar 28.

5.

Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance.

Javid B, Sorrentino F, Toosky M, Zheng W, Pinkham JT, Jain N, Pan M, Deighan P, Rubin EJ.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1132-7. doi: 10.1073/pnas.1317580111. Epub 2014 Jan 6.

6.

Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system.

Montero-Diez C, Deighan P, Osmundson J, Darst SA, Hochschild A.

J Bacteriol. 2013 Aug;195(16):3621-8. doi: 10.1128/JB.00499-13. Epub 2013 Jun 7.

7.

Efficient and specific gene knockdown by small interfering RNAs produced in bacteria.

Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J.

Nat Biotechnol. 2013 Apr;31(4):350-6. doi: 10.1038/nbt.2537. Epub 2013 Mar 10.

8.

Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the β-subunit flap domain of Escherichia coli RNA polymerase.

Twist KA, Campbell EA, Deighan P, Nechaev S, Jain V, Geiduschek EP, Hochschild A, Darst SA.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19961-6. doi: 10.1073/pnas.1113328108. Epub 2011 Dec 1.

9.

Initial transcribed region sequences influence the composition and functional properties of the bacterial elongation complex.

Deighan P, Pukhrambam C, Nickels BE, Hochschild A.

Genes Dev. 2011 Jan 1;25(1):77-88. doi: 10.1101/gad.1991811.

10.

A regulator from Chlamydia trachomatis modulates the activity of RNA polymerase through direct interaction with the beta subunit and the primary sigma subunit.

Rao X, Deighan P, Hua Z, Hu X, Wang J, Luo M, Wang J, Liang Y, Zhong G, Hochschild A, Shen L.

Genes Dev. 2009 Aug 1;23(15):1818-29. doi: 10.1101/gad.1784009.

11.

The bacteriophage lambda Q antiterminator protein contacts the beta-flap domain of RNA polymerase.

Deighan P, Diez CM, Leibman M, Hochschild A, Nickels BE.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15305-10. doi: 10.1073/pnas.0805757105. Epub 2008 Oct 1.

13.

Conformational toggle triggers a modulator of RNA polymerase activity.

Deighan P, Hochschild A.

Trends Biochem Sci. 2006 Aug;31(8):424-6. Epub 2006 Jul 11. Review.

PMID:
16815708
14.
15.

An artificial activator that contacts a normally occluded surface of the RNA polymerase holoenzyme.

Gregory BD, Deighan P, Hochschild A.

J Mol Biol. 2005 Oct 28;353(3):497-506. Epub 2005 Sep 2.

PMID:
16185714
16.

Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh protein.

Beloin C, Deighan P, Doyle M, Dorman CJ.

Mol Genet Genomics. 2003 Oct;270(1):66-77. Epub 2003 Aug 1.

PMID:
12898223
17.
18.

Regulation of gene expression by histone-like proteins in bacteria.

Dorman CJ, Deighan P.

Curr Opin Genet Dev. 2003 Apr;13(2):179-84. Review.

PMID:
12672495
19.
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