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Items: 1 to 50 of 51

1.

Exploring the Potential Role of Moonlighting Function of the Surface-Associated Proteins From Mycobacterium bovis BCG Moreau and Pasteur by Comparative Proteomic.

Pagani TD, Guimarães ACR, Waghabi MC, Corrêa PR, Kalume DE, Berrêdo-Pinho M, Degrave WM, Mendonça-Lima L.

Front Immunol. 2019 Apr 26;10:716. doi: 10.3389/fimmu.2019.00716. eCollection 2019.

2.

Integrated analysis of ethionamide resistance loci in Mycobacterium tuberculosis clinical isolates.

da Silva DA, Ferreira NV, Rego AM, Barbosa PCP, Machado RF, Pimentel A, Dos Reis LM, de Pina LC, Redner P, Caldas PCS, Fandinho-Montes FCO, Borga L, Leite SP, da Rocha JL, Bastos LS, Ramos JP, Degrave WM, Antunes LCM, Galvão TC.

Tuberculosis (Edinb). 2018 Dec;113:163-174. doi: 10.1016/j.tube.2018.08.010. Epub 2018 Aug 26.

PMID:
30514498
3.

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries.

Pillai G, Chibale K, Constable EC, Keller AN, Gutierrez MM, Mirza F, Sengstag C, Masimirembwa C, Denti P, Maartens G, Ramsay M, Ogutu B, Makonnen E, Gordon R, Ferreira CG, Goldbaum FA, Degrave WMS, Spector J, Tadmor B, Kaiser HJ.

BMC Med Educ. 2018 Oct 10;18(1):233. doi: 10.1186/s12909-018-1331-y.

4.

Brazilian Response to Global End TB Strategy : The National Tuberculosis Research Agenda.

Kritski A, Barreira D, Junqueira-Kipnis AP, Moraes MO, Campos MM, Degrave WM, Miranda SS, Krieger MA, Chimara E, Morel C, Dalcolmo MP, Maciel EL, Evangelista Mdo S, Villa TS, Sanchez M, Costa FD, Queiroz I, Oliveira MM, Souza Junior R, Silva JRL, Ruffino-Netto A.

Rev Soc Bras Med Trop. 2016 Feb;49(1):135-45. doi: 10.1590/0037-8682-0330-2015. No abstract available.

5.

Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion.

Ferrão PM, d'Avila-Levy CM, Araujo-Jorge TC, Degrave WM, Gonçalves Ada S, Garzoni LR, Lima AP, Feige JJ, Bailly S, Mendonça-Lima L, Waghabi MC.

PLoS One. 2015 May 4;10(5):e0124832. doi: 10.1371/journal.pone.0124832. eCollection 2015.

6.

The BCG Moreau RD16 deletion inactivates a repressor reshaping transcription of an adjacent gene.

Galvão TC, Lima CR, Gomes LH, Pagani TD, Ferreira MA, Gonçalves AS, Correa PR, Degrave WM, Mendonça-Lima L.

Tuberculosis (Edinb). 2014 Jan;94(1):26-33. doi: 10.1016/j.tube.2013.11.004. Epub 2013 Nov 26.

PMID:
24332305
7.

Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease.

de Oliveira FL, Araújo-Jorge TC, de Souza EM, de Oliveira GM, Degrave WM, Feige JJ, Bailly S, Waghabi MC.

PLoS Negl Trop Dis. 2012;6(6):e1696. doi: 10.1371/journal.pntd.0001696. Epub 2012 Jun 12.

8.

A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology.

Ferrão PM, de Oliveira FL, Degrave WM, Araujo-Jorge TC, Mendonça-Lima L, Waghabi MC.

PLoS One. 2012;7(6):e38736. doi: 10.1371/journal.pone.0038736. Epub 2012 Jun 12.

9.

Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis.

Gomes LH, Otto TD, Vasconcellos EA, Ferrão PM, Maia RM, Moreira AS, Ferreira MA, Castello-Branco LR, Degrave WM, Mendonça-Lima L.

J Bacteriol. 2011 Oct;193(19):5600-1. doi: 10.1128/JB.05827-11.

10.

Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur.

Berrêdo-Pinho M, Kalume DE, Correa PR, Gomes LH, Pereira MP, da Silva RF, Castello-Branco LR, Degrave WM, Mendonça-Lima L.

BMC Microbiol. 2011 Apr 20;11:80. doi: 10.1186/1471-2180-11-80.

11.

Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.

Capriles PV, Guimarães AC, Otto TD, Miranda AB, Dardenne LE, Degrave WM.

BMC Genomics. 2010 Oct 29;11:610. doi: 10.1186/1471-2164-11-610.

12.

Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.

de Saldanha da Gama Fischer J, Costa Carvalho P, da Fonseca CO, Liao L, Degrave WM, da Gloria da Costa Carvalho M, Yates JR, Domont GB.

J Proteome Res. 2011 Jan 7;10(1):153-60. doi: 10.1021/pr100677g. Epub 2010 Sep 27.

13.

A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information.

Alves-Ferreira M, Guimarães AC, Capriles PV, Dardenne LE, Degrave WM.

Mem Inst Oswaldo Cruz. 2009 Dec;104(8):1100-10.

14.

Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection.

Coutinho L, Ferreira MA, Cosson A, Batista MM, Batista Dda G, Minoprio P, Degrave WM, Berneman A, Soeiro Mde N.

Mem Inst Oswaldo Cruz. 2009 Dec;104(8):1055-62.

15.

GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data.

Carvalho PC, Fischer JS, Chen EI, Domont GB, Carvalho MG, Degrave WM, Yates JR 3rd, Barbosa VC.

Proteome Sci. 2009 Feb 24;7:6. doi: 10.1186/1477-5956-7-6.

16.

AnEnPi: identification and annotation of analogous enzymes.

Otto TD, Guimarães AC, Degrave WM, de Miranda AB.

BMC Bioinformatics. 2008 Dec 17;9:544. doi: 10.1186/1471-2105-9-544.

17.

In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi.

Guimarães AC, Otto TD, Alves-Ferreira M, Miranda AB, Degrave WM.

Genet Mol Res. 2008 Sep 23;7(3):872-82.

18.

ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility.

Otto TD, Vasconcellos EA, Gomes LH, Moreira AS, Degrave WM, Mendonça-Lima L, Alves-Ferreira M.

Genet Mol Res. 2008 Sep 23;7(3):861-71.

19.

ReRep: computational detection of repetitive sequences in genome survey sequences (GSS).

Otto TD, Gomes LH, Alves-Ferreira M, de Miranda AB, Degrave WM.

BMC Bioinformatics. 2008 Sep 9;9:366. doi: 10.1186/1471-2105-9-366.

20.

Investigation of a protein expression profile by high-resolution bidimensional electrophoresis of Trypanosoma cruzi epimastigotes.

Souza RA, Henriques C, Alves-Ferreira M, Mendonça-Lima L, Degrave WM.

Anal Biochem. 2007 Jun 1;365(1):144-6. Epub 2007 Jan 13. No abstract available.

PMID:
17418799
21.

Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity.

Chamond N, Goytia M, Coatnoan N, Barale JC, Cosson A, Degrave WM, Minoprio P.

Mol Microbiol. 2005 Oct;58(1):46-60.

22.

Squid - a simple bioinformatics grid.

Carvalho PC, Glória RV, de Miranda AB, Degrave WM.

BMC Bioinformatics. 2005 Aug 3;6:197.

23.

Towards a bioinformatics network for Latin America and the Caribbean (LACBioNet).

Degrave WM, Vargas R, Alvarez F, Collado-Vides J, Nuñez L, Ramirez JL, Grau O.

Appl Bioinformatics. 2002;1(1):53-6.

PMID:
15130857
24.

Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis.

Nascimento AL, Ko AI, Martins EA, Monteiro-Vitorello CB, Ho PL, Haake DA, Verjovski-Almeida S, Hartskeerl RA, Marques MV, Oliveira MC, Menck CF, Leite LC, Carrer H, Coutinho LL, Degrave WM, Dellagostin OA, El-Dorry H, Ferro ES, Ferro MI, Furlan LR, Gamberini M, Giglioti EA, Góes-Neto A, Goldman GH, Goldman MH, Harakava R, Jerônimo SM, Junqueira-de-Azevedo IL, Kimura ET, Kuramae EE, Lemos EG, Lemos MV, Marino CL, Nunes LR, de Oliveira RC, Pereira GG, Reis MS, Schriefer A, Siqueira WJ, Sommer P, Tsai SM, Simpson AJ, Ferro JA, Camargo LE, Kitajima JP, Setubal JC, Van Sluys MA.

J Bacteriol. 2004 Apr;186(7):2164-72.

25.

TcruziDB: an integrated Trypanosoma cruzi genome resource.

Luchtan M, Warade C, Weatherly DB, Degrave WM, Tarleton RL, Kissinger JC.

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D344-6.

26.

Biochemical characterization of proline racemases from the human protozoan parasite Trypanosoma cruzi and definition of putative protein signatures.

Chamond N, Grégoire C, Coatnoan N, Rougeot C, Freitas-Junior LH, da Silveira JF, Degrave WM, Minoprio P.

J Biol Chem. 2003 May 2;278(18):15484-94.

27.

Novel allelic variants of Mycobacteria isolated in Brazil as determined by PCR-restriction enzyme analysis of hsp65.

da Silva Rocha A, Werneck Barreto AM, Dias Campos CE, Villas-Bôas da Silva M, Fonseca L, Saad MH, Degrave WM, Suffys PN.

J Clin Microbiol. 2002 Nov;40(11):4191-6.

28.

Comparative evaluation of Mycobacterium vaccae as a surrogate cloning host for use in the study of mycobacterial genetics.

Medeiros MA, Dellagostin OA, Armôa GR, Degrave WM, De Mendonça-Lima L, Lopes MQ, Costa JF, McFadden J, McIntosh D.

Microbiology. 2002 Jul;148(Pt 7):1999-2009.

PMID:
12101288
29.

Detection of Mycobacterium leprae DNA by polymerase chain reaction in the blood of individuals, eight years after completion of anti-leprosy therapy.

Santos AR, Balassiano V, Oliveira ML, Pereira MA, Santos PB, Degrave WM, Suffys PN.

Mem Inst Oswaldo Cruz. 2001 Nov;96(8):1129-33.

30.

Parasite genome initiatives.

Degrave WM, Melville S, Ivens A, Aslett M.

Int J Parasitol. 2001 May 1;31(5-6):532-6. Review.

PMID:
11334938
31.

The heterogeneity of choanomastigote-shaped trypanosomatids as analyzed by their kDNA minicircle size: taxonomic implicaitons.

Brandão AA, Miranda A, Degrave WM, Sousa MA.

Parasitol Res. 2000 Oct;86(10):809-12.

PMID:
11068813
32.

Usefulness of IS6110-restriction fragment length polymorphism typing of Brazilian strains of Mycobacterium tuberculosis and comparison with an international fingerprint database.

Suffys PN, Ivens de Araujo ME, Rossetti ML, Zahab A, Barroso EW, Barreto AM, Campos E, van Soolingen D, Kremer K, Heersma H, Degrave WM.

Res Microbiol. 2000 Jun;151(5):343-51.

PMID:
10919514
33.
34.

Physical mapping of a 670-kb region of chromosomes XVI and XVII from the human protozoan parasite Trypanosoma cruzi encompassing the genes for two immunodominant antigens.

Santos MR, Lorenzi H, Porcile P, Carmo MS, Schijman A, Brandão A, Araya JE, Gomes HB, Chiurillo MA, Ramirez JL, Degrave WM, Levin MJ, da Silveira JF.

Genome Res. 1999 Dec;9(12):1268-76.

35.

Use of PCR-restriction fragment length polymorphism analysis of the hsp65 gene for rapid identification of mycobacteria in Brazil.

da Silva Rocha A, da Costa Leite C, Torres HM, de Miranda AB, Pires Lopes MQ, Degrave WM, Suffys PN.

J Microbiol Methods. 1999 Sep;37(3):223-9.

PMID:
10480266
36.

Use of polymerase chain reaction (PCR) in leprosy research.

Santos AR, Degrave WM, Suffys PN.

Indian J Lepr. 1999 Jan-Mar;71(1):101-10. Review. No abstract available.

PMID:
10439331
37.

Cystic fibrosis: low frequency of DF508 mutation in 2 population samples from Rio de Janeiro, Brazil.

Cabello GM, Moreira AF, Horovitz D, Correia P, Santa Rosa A, Llerena J Jr, Greg J, Grody WW, Degrave WM, Fernandes O, Cabello PH.

Hum Biol. 1999 Apr;71(2):189-96.

PMID:
10222642
38.

Genomics and the biology of parasites.

Johnston DA, Blaxter ML, Degrave WM, Foster J, Ivens AC, Melville SE.

Bioessays. 1999 Feb;21(2):131-47. Review.

PMID:
10193187
39.

DNA fingerprinting of Mycobacterium tuberculosis from patients with and without AIDS in Rio de Janeiro.

Ivens-de-Araujo ME, Fandinho FC, Werneck-Barreto AM, Gonçalves-Veloso V, Grinstejn B, Lourenço MK, Werneck-Barroso E, Degrave WM, Suffys PN.

Braz J Med Biol Res. 1998 Mar;31(3):369-72.

PMID:
9698784
40.

The Trypanosoma cruzi genome project: nuclear karyotype and gene mapping of clone CL Brener.

Santos MR, Cano MI, Schijman A, Lorenzi H, Vázquez M, Levin MJ, Ramirez JL, Brandão A, Degrave WM, da Silveira JF.

Mem Inst Oswaldo Cruz. 1997 Nov-Dec;92(6):821-8. Review.

41.

Mini-exon gene sequences define six groups within the genus Crithidia.

Fernandes O, Teixeira MM, Sturm NR, Sousa MA, Camargo EP, Degrave WM, Campbell DA.

J Eukaryot Microbiol. 1997 Nov-Dec;44(6):535-9.

PMID:
9435125
42.

The changing face of the epidemiology of tuberculosis due to molecular strain typing--a review.

Suffys PN, de Araujo ME, Degrave WM.

Mem Inst Oswaldo Cruz. 1997 May-Jun;92(3):297-316. Review.

43.

Use of the polymerase chain reaction in the diagnosis of leprosy.

Santos AR, Nery JC, Duppre NC, Gallo ME, Filho JT, Suffys PN, Degrave WM.

J Med Microbiol. 1997 Feb;46(2):170-2.

PMID:
9060878
44.

An oligonucleotide probe derived from kDNA minirepeats is specific for Leishmania (Viannia).

Fernandes O, Bozza M, Pascale JM, de Miranda AB, Lopes UG, Degrave WM.

Mem Inst Oswaldo Cruz. 1996 May-Jun;91(3):279-84.

45.

Characterization of 'Old World' Leishmania species using amplified minicircle variable regions as molecular probes.

Bozza M, Fernandes O, Degrave WM, Lopes UG.

Trans R Soc Trop Med Hyg. 1995 May-Jun;89(3):333-4. No abstract available.

PMID:
7660454
46.

Evaluation of PCR mediated DNA amplification in non-invasive biological specimens for subclinical detection of Mycobacterium leprae.

Santos AR, Goes Filho JT, Nery JA, Duppre NC, Gallo ME, Suffys PN, Degrave WM.

FEMS Immunol Med Microbiol. 1995 Apr;11(2):113-20.

PMID:
7640671
47.
48.

Mini-exon gene variation in human pathogenic Leishmania species.

Fernandes O, Murthy VK, Kurath U, Degrave WM, Campbell DA.

Mol Biochem Parasitol. 1994 Aug;66(2):261-71.

PMID:
7808476
49.

Use of PCR-mediated amplification of Mycobacterium leprae DNA in different types of clinical samples for the diagnosis of leprosy.

Santos AR, De Miranda AB, Sarno EN, Suffys PN, Degrave WM.

J Med Microbiol. 1993 Oct;39(4):298-304.

PMID:
8411091
50.

Use of PCR for the determination of the frequency of the delta F508 mutation in Brazilian cystic fibrosis patients.

de Miranda AB, Llerena Júnior J, Dallalana LT, Moura-Neto RS, Suffys PN, Degrave WM.

Mem Inst Oswaldo Cruz. 1993 Apr-Jun;88(2):309-12.

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