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Items: 1 to 50 of 97

1.

Integrated analysis of ethionamide resistance loci in Mycobacterium tuberculosis clinical isolates.

da Silva DA, Ferreira NV, Rego AM, Barbosa PCP, Machado RF, Pimentel A, Dos Reis LM, de Pina LC, Redner P, Caldas PCS, Fandinho-Montes FCO, Borga L, Leite SP, da Rocha JL, Bastos LS, Ramos JP, Degrave WM, Antunes LCM, Galvão TC.

Tuberculosis (Edinb). 2018 Dec;113:163-174. doi: 10.1016/j.tube.2018.08.010. Epub 2018 Aug 26.

PMID:
30514498
2.

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries.

Pillai G, Chibale K, Constable EC, Keller AN, Gutierrez MM, Mirza F, Sengstag C, Masimirembwa C, Denti P, Maartens G, Ramsay M, Ogutu B, Makonnen E, Gordon R, Ferreira CG, Goldbaum FA, Degrave WMS, Spector J, Tadmor B, Kaiser HJ.

BMC Med Educ. 2018 Oct 10;18(1):233. doi: 10.1186/s12909-018-1331-y.

3.

Zika virus evolution and spread in the Americas.

Metsky HC, Matranga CB, Wohl S, Schaffner SF, Freije CA, Winnicki SM, West K, Qu J, Baniecki ML, Gladden-Young A, Lin AE, Tomkins-Tinch CH, Ye SH, Park DJ, Luo CY, Barnes KG, Shah RR, Chak B, Barbosa-Lima G, Delatorre E, Vieira YR, Paul LM, Tan AL, Barcellona CM, Porcelli MC, Vasquez C, Cannons AC, Cone MR, Hogan KN, Kopp EW, Anzinger JJ, Garcia KF, Parham LA, Ramírez RMG, Montoya MCM, Rojas DP, Brown CM, Hennigan S, Sabina B, Scotland S, Gangavarapu K, Grubaugh ND, Oliveira G, Robles-Sikisaka R, Rambaut A, Gehrke L, Smole S, Halloran ME, Villar L, Mattar S, Lorenzana I, Cerbino-Neto J, Valim C, Degrave W, Bozza PT, Gnirke A, Andersen KG, Isern S, Michael SF, Bozza FA, Souza TML, Bosch I, Yozwiak NL, MacInnis BL, Sabeti PC.

Nature. 2017 Jun 15;546(7658):411-415. doi: 10.1038/nature22402. Epub 2017 May 24.

4.

Brazilian Response to Global End TB Strategy : The National Tuberculosis Research Agenda.

Kritski A, Barreira D, Junqueira-Kipnis AP, Moraes MO, Campos MM, Degrave WM, Miranda SS, Krieger MA, Chimara E, Morel C, Dalcolmo MP, Maciel EL, Evangelista Mdo S, Villa TS, Sanchez M, Costa FD, Queiroz I, Oliveira MM, Souza Junior R, Silva JRL, Ruffino-Netto A.

Rev Soc Bras Med Trop. 2016 Feb;49(1):135-45. doi: 10.1590/0037-8682-0330-2015. No abstract available.

5.

Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome.

Henriques C, Miller MP, Catanho M, de Carvalho TM, Krieger MA, Probst CM, de Souza W, Degrave W, Amara SG.

Parasit Vectors. 2015 Jun 25;8:346. doi: 10.1186/s13071-015-0950-y.

6.

Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion.

Ferrão PM, d'Avila-Levy CM, Araujo-Jorge TC, Degrave WM, Gonçalves Ada S, Garzoni LR, Lima AP, Feige JJ, Bailly S, Mendonça-Lima L, Waghabi MC.

PLoS One. 2015 May 4;10(5):e0124832. doi: 10.1371/journal.pone.0124832. eCollection 2015.

7.

The BCG Moreau RD16 deletion inactivates a repressor reshaping transcription of an adjacent gene.

Galvão TC, Lima CR, Gomes LH, Pagani TD, Ferreira MA, Gonçalves AS, Correa PR, Degrave WM, Mendonça-Lima L.

Tuberculosis (Edinb). 2014 Jan;94(1):26-33. doi: 10.1016/j.tube.2013.11.004. Epub 2013 Nov 26.

PMID:
24332305
8.

Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease.

de Oliveira FL, Araújo-Jorge TC, de Souza EM, de Oliveira GM, Degrave WM, Feige JJ, Bailly S, Waghabi MC.

PLoS Negl Trop Dis. 2012;6(6):e1696. doi: 10.1371/journal.pntd.0001696. Epub 2012 Jun 12.

9.

A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology.

Ferrão PM, de Oliveira FL, Degrave WM, Araujo-Jorge TC, Mendonça-Lima L, Waghabi MC.

PLoS One. 2012;7(6):e38736. doi: 10.1371/journal.pone.0038736. Epub 2012 Jun 12.

10.

Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis.

Gomes LH, Otto TD, Vasconcellos EA, Ferrão PM, Maia RM, Moreira AS, Ferreira MA, Castello-Branco LR, Degrave WM, Mendonça-Lima L.

J Bacteriol. 2011 Oct;193(19):5600-1. doi: 10.1128/JB.05827-11.

11.

Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur.

Berrêdo-Pinho M, Kalume DE, Correa PR, Gomes LH, Pereira MP, da Silva RF, Castello-Branco LR, Degrave WM, Mendonça-Lima L.

BMC Microbiol. 2011 Apr 20;11:80. doi: 10.1186/1471-2180-11-80.

12.

RATT: Rapid Annotation Transfer Tool.

Otto TD, Dillon GP, Degrave WS, Berriman M.

Nucleic Acids Res. 2011 May;39(9):e57. doi: 10.1093/nar/gkq1268. Epub 2011 Feb 8.

13.

Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.

Capriles PV, Guimarães AC, Otto TD, Miranda AB, Dardenne LE, Degrave WM.

BMC Genomics. 2010 Oct 29;11:610. doi: 10.1186/1471-2164-11-610.

14.

Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.

de Saldanha da Gama Fischer J, Costa Carvalho P, da Fonseca CO, Liao L, Degrave WM, da Gloria da Costa Carvalho M, Yates JR, Domont GB.

J Proteome Res. 2011 Jan 7;10(1):153-60. doi: 10.1021/pr100677g. Epub 2010 Sep 27.

15.

In vitro and in vivo experimental models for drug screening and development for Chagas disease.

Romanha AJ, Castro SL, Soeiro Mde N, Lannes-Vieira J, Ribeiro I, Talvani A, Bourdin B, Blum B, Olivieri B, Zani C, Spadafora C, Chiari E, Chatelain E, Chaves G, Calzada JE, Bustamante JM, Freitas-Junior LH, Romero LI, Bahia MT, Lotrowska M, Soares M, Andrade SG, Armstrong T, Degrave W, Andrade Zde A.

Mem Inst Oswaldo Cruz. 2010 Mar;105(2):233-8.

16.

A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information.

Alves-Ferreira M, Guimarães AC, Capriles PV, Dardenne LE, Degrave WM.

Mem Inst Oswaldo Cruz. 2009 Dec;104(8):1100-10.

17.

Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection.

Coutinho L, Ferreira MA, Cosson A, Batista MM, Batista Dda G, Minoprio P, Degrave WM, Berneman A, Soeiro Mde N.

Mem Inst Oswaldo Cruz. 2009 Dec;104(8):1055-62.

18.

ProteinWorldDB: querying radical pairwise alignments among protein sets from complete genomes.

Otto TD, Catanho M, Tristão C, Bezerra M, Fernandes RM, Elias GS, Scaglia AC, Bovermann B, Berstis V, Lifschitz S, de Miranda AB, Degrave W.

Bioinformatics. 2010 Mar 1;26(5):705-7. doi: 10.1093/bioinformatics/btq011. Epub 2010 Jan 19.

19.

GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data.

Carvalho PC, Fischer JS, Chen EI, Domont GB, Carvalho MG, Degrave WM, Yates JR 3rd, Barbosa VC.

Proteome Sci. 2009 Feb 24;7:6. doi: 10.1186/1477-5956-7-6.

20.

AnEnPi: identification and annotation of analogous enzymes.

Otto TD, Guimarães AC, Degrave WM, de Miranda AB.

BMC Bioinformatics. 2008 Dec 17;9:544. doi: 10.1186/1471-2105-9-544.

21.

In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi.

Guimarães AC, Otto TD, Alves-Ferreira M, Miranda AB, Degrave WM.

Genet Mol Res. 2008 Sep 23;7(3):872-82.

22.

ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility.

Otto TD, Vasconcellos EA, Gomes LH, Moreira AS, Degrave WM, Mendonça-Lima L, Alves-Ferreira M.

Genet Mol Res. 2008 Sep 23;7(3):861-71.

23.

ReRep: computational detection of repetitive sequences in genome survey sequences (GSS).

Otto TD, Gomes LH, Alves-Ferreira M, de Miranda AB, Degrave WM.

BMC Bioinformatics. 2008 Sep 9;9:366. doi: 10.1186/1471-2105-9-366.

24.

Typing of Mycobacterium tuberculosis strains isolated in Community Health Centers of Rio de Janeiro City, Brazil.

Oelemann MC, Fontes AN, Pereira MA, Bravin Y, Silva G, Degrave W, Carvalho AC, Brito RC, Kritski AL, Suffys PN.

Mem Inst Oswaldo Cruz. 2007 Jun;102(4):455-62.

25.

Investigation of a protein expression profile by high-resolution bidimensional electrophoresis of Trypanosoma cruzi epimastigotes.

Souza RA, Henriques C, Alves-Ferreira M, Mendonça-Lima L, Degrave WM.

Anal Biochem. 2007 Jun 1;365(1):144-6. Epub 2007 Jan 13. No abstract available.

PMID:
17418799
26.

Differential protein expression patterns obtained by mass spectrometry can aid in the diagnosis of Hodgkin's disease.

Carvalho PC, Carvalho Mda G, Degrave W, Lilla S, De Nucci G, Fonseca R, Spector N, Musacchio J, Domont GB.

J Exp Ther Oncol. 2007;6(2):137-45.

PMID:
17407972
27.

Personalized diagnosis by cached solutions with hypertension as a study model.

Carvalho PC, Freitas SS, Lima AB, Barros M, Bittencourt I, Degrave W, Cordovil I, Fonseca R, Carvalho MG, Moura Neto RS, Cabello PH.

Genet Mol Res. 2006 Dec 18;5(4):856-67.

28.

GenoMycDB: a database for comparative analysis of mycobacterial genes and genomes.

Catanho M, Mascarenhas D, Degrave W, Miranda AB.

Genet Mol Res. 2006 Mar 31;5(1):115-26.

29.

BioParser: a tool for processing of sequence similarity analysis reports.

Catanho M, Mascarenhas D, Degrave W, de Miranda AB.

Appl Bioinformatics. 2006;5(1):49-53.

PMID:
16539538
30.

Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase.

Buschiazzo A, Goytia M, Schaeffer F, Degrave W, Shepard W, Grégoire C, Chamond N, Cosson A, Berneman A, Coatnoan N, Alzari PM, Minoprio P.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1705-10. Epub 2006 Jan 30.

31.

Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.

Waghabi MC, Keramidas M, Bailly S, Degrave W, Mendonça-Lima L, Soeiro Mde N, Meirelles Mde N, Paciornik S, Araújo-Jorge TC, Feige JJ.

Am J Pathol. 2005 Oct;167(4):993-1003.

32.

Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity.

Chamond N, Goytia M, Coatnoan N, Barale JC, Cosson A, Degrave WM, Minoprio P.

Mol Microbiol. 2005 Oct;58(1):46-60.

33.

Squid - a simple bioinformatics grid.

Carvalho PC, Glória RV, de Miranda AB, Degrave WM.

BMC Bioinformatics. 2005 Aug 3;6:197.

34.

Minicircle organization and diversity in Trypanosoma cruzi populations.

Junqueira AC, Degrave W, Brandão A.

Trends Parasitol. 2005 Jun;21(6):270-2. Review.

PMID:
15922247
35.

A survey of Leishmania braziliensis genome by shotgun sequencing.

Laurentino EC, Ruiz JC, Fazelinia G, Myler PJ, Degrave W, Alves-Ferreira M, Ribeiro JM, Cruz AK.

Mol Biochem Parasitol. 2004 Sep;137(1):81-6.

PMID:
15279954
36.

Towards a bioinformatics network for Latin America and the Caribbean (LACBioNet).

Degrave WM, Vargas R, Alvarez F, Collado-Vides J, Nuñez L, Ramirez JL, Grau O.

Appl Bioinformatics. 2002;1(1):53-6.

PMID:
15130857
37.

Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis.

Nascimento AL, Ko AI, Martins EA, Monteiro-Vitorello CB, Ho PL, Haake DA, Verjovski-Almeida S, Hartskeerl RA, Marques MV, Oliveira MC, Menck CF, Leite LC, Carrer H, Coutinho LL, Degrave WM, Dellagostin OA, El-Dorry H, Ferro ES, Ferro MI, Furlan LR, Gamberini M, Giglioti EA, Góes-Neto A, Goldman GH, Goldman MH, Harakava R, Jerônimo SM, Junqueira-de-Azevedo IL, Kimura ET, Kuramae EE, Lemos EG, Lemos MV, Marino CL, Nunes LR, de Oliveira RC, Pereira GG, Reis MS, Schriefer A, Siqueira WJ, Sommer P, Tsai SM, Simpson AJ, Ferro JA, Camargo LE, Kitajima JP, Setubal JC, Van Sluys MA.

J Bacteriol. 2004 Apr;186(7):2164-72.

38.

TcruziDB: an integrated Trypanosoma cruzi genome resource.

Luchtan M, Warade C, Weatherly DB, Degrave WM, Tarleton RL, Kissinger JC.

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D344-6.

39.

Biochemical characterization of proline racemases from the human protozoan parasite Trypanosoma cruzi and definition of putative protein signatures.

Chamond N, Grégoire C, Coatnoan N, Rougeot C, Freitas-Junior LH, da Silveira JF, Degrave WM, Minoprio P.

J Biol Chem. 2003 May 2;278(18):15484-94.

40.

A refined molecular karyotype for the reference strain of the Trypanosoma cruzi genome project (clone CL Brener) by assignment of chromosome markers.

Porcile PE, Santos MR, Souza RT, Verbisck NV, Brandão A, Urmenyi T, Silva R, Rondinelli E, Lorenzi H, Levin MJ, Degrave W, Franco da Silveira J.

Gene. 2003 Apr 10;308:53-65.

PMID:
12711390
41.

Novel allelic variants of Mycobacteria isolated in Brazil as determined by PCR-restriction enzyme analysis of hsp65.

da Silva Rocha A, Werneck Barreto AM, Dias Campos CE, Villas-Bôas da Silva M, Fonseca L, Saad MH, Degrave WM, Suffys PN.

J Clin Microbiol. 2002 Nov;40(11):4191-6.

42.

Comparative evaluation of Mycobacterium vaccae as a surrogate cloning host for use in the study of mycobacterial genetics.

Medeiros MA, Dellagostin OA, Armôa GR, Degrave WM, De Mendonça-Lima L, Lopes MQ, Costa JF, McFadden J, McIntosh D.

Microbiology. 2002 Jul;148(Pt 7):1999-2009.

PMID:
12101288
43.

Detection of Mycobacterium leprae DNA by polymerase chain reaction in the blood of individuals, eight years after completion of anti-leprosy therapy.

Santos AR, Balassiano V, Oliveira ML, Pereira MA, Santos PB, Degrave WM, Suffys PN.

Mem Inst Oswaldo Cruz. 2001 Nov;96(8):1129-33.

44.

Parasite genome initiatives.

Degrave WM, Melville S, Ivens A, Aslett M.

Int J Parasitol. 2001 May 1;31(5-6):532-6. Review.

PMID:
11334938
45.

Intraspecific heterogeneity in the mini-exon gene localization of Leishmania (Viannia) panamensis and Leishmania (Viannia) guyanensis from Colombia.

Pacheco RS, Fernandes O, Salinas G, Segura I, Momen H, Degrave W, Saravia NG, Campbell DA.

J Parasitol. 2000 Dec;86(6):1250-3.

PMID:
11191900
46.

The heterogeneity of choanomastigote-shaped trypanosomatids as analyzed by their kDNA minicircle size: taxonomic implicaitons.

Brandão AA, Miranda A, Degrave WM, Sousa MA.

Parasitol Res. 2000 Oct;86(10):809-12.

PMID:
11068813
47.

A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase.

Reina-San-Martín B, Degrave W, Rougeot C, Cosson A, Chamond N, Cordeiro-Da-Silva A, Arala-Chaves M, Coutinho A, Minoprio P.

Nat Med. 2000 Aug;6(8):890-7.

PMID:
10932226
48.

Usefulness of IS6110-restriction fragment length polymorphism typing of Brazilian strains of Mycobacterium tuberculosis and comparison with an international fingerprint database.

Suffys PN, Ivens de Araujo ME, Rossetti ML, Zahab A, Barroso EW, Barreto AM, Campos E, van Soolingen D, Kremer K, Heersma H, Degrave WM.

Res Microbiol. 2000 Jun;151(5):343-51.

PMID:
10919514
49.
50.

Physical mapping of a 670-kb region of chromosomes XVI and XVII from the human protozoan parasite Trypanosoma cruzi encompassing the genes for two immunodominant antigens.

Santos MR, Lorenzi H, Porcile P, Carmo MS, Schijman A, Brandão A, Araya JE, Gomes HB, Chiurillo MA, Ramirez JL, Degrave WM, Levin MJ, da Silveira JF.

Genome Res. 1999 Dec;9(12):1268-76.

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