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Items: 26

1.

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

Steffens N, Beuter-Gunia C, Kravets E, Reich A, Legewie L, Pfeffer K, Degrandi D.

mBio. 2020 Jan 21;11(1). pii: e02993-19. doi: 10.1128/mBio.02993-19.

2.

Biochemical and structural characterization of murine GBP7, a guanylate binding protein with an elongated C-terminal tail.

Legewie L, Loschwitz J, Steffens N, Prescher M, Wang X, Smits SHJ, Schmitt L, Strodel B, Degrandi D, Pfeffer K.

Biochem J. 2019 Nov 15;476(21):3161-3182. doi: 10.1042/BCJ20190364.

PMID:
31689351
3.

Gymnotic Delivery of LNA Mixmers Targeting Viral SREs Induces HIV-1 mRNA Degradation.

Hillebrand F, Ostermann PN, Müller L, Degrandi D, Erkelenz S, Widera M, Pfeffer K, Schaal H.

Int J Mol Sci. 2019 Mar 3;20(5). pii: E1088. doi: 10.3390/ijms20051088.

4.

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

Santos JC, Dick MS, Lagrange B, Degrandi D, Pfeffer K, Yamamoto M, Meunier E, Pelczar P, Henry T, Broz P.

EMBO J. 2018 Mar 15;37(6). pii: e98089. doi: 10.15252/embj.201798089. Epub 2018 Feb 19.

5.

Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions.

Lindenberg V, Mölleken K, Kravets E, Stallmann S, Hegemann JH, Degrandi D, Pfeffer K.

PLoS One. 2017 Sep 25;12(9):e0185273. doi: 10.1371/journal.pone.0185273. eCollection 2017.

6.

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes.

Kravets E, Degrandi D, Ma Q, Peulen TO, Klümpers V, Felekyan S, Kühnemuth R, Weidtkamp-Peters S, Seidel CA, Pfeffer K.

Elife. 2016 Jan 27;5. pii: e11479. doi: 10.7554/eLife.11479.

7.

Cooperative role of lymphotoxin β receptor and tumor necrosis factor receptor p55 in murine liver regeneration.

Sorg UR, Behnke K, Degrandi D, Reich M, Keitel V, Herebian D, Deenen R, Beyer M, Schultze JL, Köhrer K, Gabbert HE, Mayatepek E, Häussinger D, Pfeffer K.

J Hepatol. 2016 May;64(5):1108-1117. doi: 10.1016/j.jhep.2015.12.006. Epub 2015 Dec 19.

PMID:
26708145
8.

Balanced splicing at the Tat-specific HIV-1 3'ss A3 is critical for HIV-1 replication.

Erkelenz S, Hillebrand F, Widera M, Theiss S, Fayyaz A, Degrandi D, Pfeffer K, Schaal H.

Retrovirology. 2015 Mar 28;12:29. doi: 10.1186/s12977-015-0154-8.

9.

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.

Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S, Dussurgey S, Dick MS, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P.

Nat Immunol. 2015 May;16(5):476-484. doi: 10.1038/ni.3119. Epub 2015 Mar 16.

10.

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

Pilla DM, Hagar JA, Haldar AK, Mason AK, Degrandi D, Pfeffer K, Ernst RK, Yamamoto M, Miao EA, Coers J.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6046-51. doi: 10.1073/pnas.1321700111. Epub 2014 Apr 8.

11.

In astrocytes the accumulation of the immunity-related GTPases Irga6 and Irgb6 at the vacuole of Toxoplasma gondii is dependent on the parasite virulence.

Lubitz FP, Degrandi D, Pfeffer K, Mausberg AK.

ScientificWorldJournal. 2013 Nov 12;2013:480231. doi: 10.1155/2013/480231. eCollection 2013.

12.

Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment.

Globisch T, Steiner N, Fülle L, Lukacs-Kornek V, Degrandi D, Dresing P, Alferink J, Lang R, Pfeffer K, Beyer M, Weighardt H, Kurts C, Ulas T, Schultze JL, Förster I.

Eur J Immunol. 2014 Feb;44(2):500-10. doi: 10.1002/eji.201343820. Epub 2013 Dec 12.

13.

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.

Selleck EM, Fentress SJ, Beatty WL, Degrandi D, Pfeffer K, Virgin HW 4th, Macmicking JD, Sibley LD.

PLoS Pathog. 2013;9(4):e1003320. doi: 10.1371/journal.ppat.1003320. Epub 2013 Apr 25.

14.

Host cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis.

Hopfe M, Deenen R, Degrandi D, Köhrer K, Henrich B.

PLoS One. 2013;8(1):e54219. doi: 10.1371/journal.pone.0054219. Epub 2013 Jan 11.

15.

Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs).

Spekker K, Leineweber M, Degrandi D, Ince V, Brunder S, Schmidt SK, Stuhlsatz S, Howard JC, Schares G, Degistirici O, Meisel R, Sorg RV, Seissler J, Hemphill A, Pfeffer K, Däubener W.

Med Microbiol Immunol. 2013 Jun;202(3):197-206. doi: 10.1007/s00430-012-0281-y. Epub 2012 Dec 27.

PMID:
23269418
16.

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

Degrandi D, Kravets E, Konermann C, Beuter-Gunia C, Klümpers V, Lahme S, Wischmann E, Mausberg AK, Beer-Hammer S, Pfeffer K.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):294-9. doi: 10.1073/pnas.1205635110. Epub 2012 Dec 17.

17.

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

Kravets E, Degrandi D, Weidtkamp-Peters S, Ries B, Konermann C, Felekyan S, Dargazanli JM, Praefcke GJ, Seidel CA, Schmitt L, Smits SH, Pfeffer K.

J Biol Chem. 2012 Aug 10;287(33):27452-66. doi: 10.1074/jbc.M112.379636. Epub 2012 Jun 22.

18.

The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.

Beer-Hammer S, Zebedin E, von Holleben M, Alferink J, Reis B, Dresing P, Degrandi D, Scheu S, Hirsch E, Sexl V, Pfeffer K, Nürnberg B, Piekorz RP.

J Leukoc Biol. 2010 Jun;87(6):1083-95. doi: 10.1189/jlb.0809585. Epub 2010 Mar 3.

PMID:
20200404
19.

The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.

Degrandi D, Hoffmann R, Beuter-Gunia C, Pfeffer K.

J Interferon Cytokine Res. 2009 Jan;29(1):55-67. doi: 10.1089/jir.2008.0013. Erratum in: J Interferon Cytokine Res. 2009 Sep;29(9):643.

PMID:
19014335
20.

Immediate lymphotoxin beta receptor-mediated transcriptional response in host defense against L. monocytogenes.

Kutsch S, Degrandi D, Pfeffer K.

Immunobiology. 2008;213(3-4):353-66. doi: 10.1016/j.imbio.2007.10.011. Epub 2007 Dec 31.

PMID:
18406380
21.

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies.

Kresse A, Konermann C, Degrandi D, Beuter-Gunia C, Wuerthner J, Pfeffer K, Beer S.

BMC Genomics. 2008 Apr 10;9:158. doi: 10.1186/1471-2164-9-158.

22.

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

Degrandi D, Konermann C, Beuter-Gunia C, Kresse A, Würthner J, Kurig S, Beer S, Pfeffer K.

J Immunol. 2007 Dec 1;179(11):7729-40.

23.

In silico and in vitro characterization of mGBP4 splice variants.

Konermann C, Kresse A, Beuter-Gunia C, Würthner J, Degrandi D, Pfeffer K, Beer S.

DNA Cell Biol. 2007 Dec;26(12):847-51.

PMID:
17919070
24.

Carboxypeptidase D: a novel TGF-beta target gene dysregulated in patients with lupus erythematosus.

Hoff NP, Degrandi D, Hengge U, Pfeffer K, Wurthner JU.

J Clin Immunol. 2007 Nov;27(6):568-79. Epub 2007 Jul 20.

PMID:
17641957
25.

The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses.

Wang Y, Subudhi SK, Anders RA, Lo J, Sun Y, Blink S, Wang Y, Wang J, Liu X, Mink K, Degrandi D, Pfeffer K, Fu YX.

J Clin Invest. 2005 Mar;115(3):711-7.

26.

[Construction of a nasal mask for treatment using assisted intermittent positive pressure ventilation in patients with neuromuscular diseases].

Lorenzetti M, Fraccari F, Bogini A, Degrandi D, Gasperini M.

Minerva Stomatol. 1989 Aug;38(8):887-91. Italian.

PMID:
2682180

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