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Items: 1 to 50 of 105

1.

Fetal cardiomyopathy in neurofibromatosis type I: Novel phenotype and review of the literature.

Ritter A, Cuddapah S, Degenhardt K, Kasperski S, Johnson MP, O'Connor MJ, Ahrens-Nicklas R.

Am J Med Genet A. 2019 Jun;179(6):1042-1046. doi: 10.1002/ajmg.a.61123. Epub 2019 Mar 28.

PMID:
30919579
2.

Innate immune memory in the brain shapes neurological disease hallmarks.

Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ.

Nature. 2018 Apr;556(7701):332-338. doi: 10.1038/s41586-018-0023-4. Epub 2018 Apr 11.

3.

Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries.

Aghajanian H, Cho YK, Rizer NW, Wang Q, Li L, Degenhardt K, Jain R.

Dis Model Mech. 2017 Sep 1;10(9):1101-1108. doi: 10.1242/dmm.029710. Epub 2017 Jul 14.

4.

Fetal Situs, Isomerism, Heterotaxy Syndrome: Diagnostic Evaluation and Implication for Postnatal Management.

Degenhardt K, Rychik J.

Curr Treat Options Cardiovasc Med. 2016 Dec;18(12):77. Review.

PMID:
27844411
5.

Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.

Liao Y, Chu HP, Hu Z, Merkin JJ, Chen J, Liu Z, Degenhardt K, White E, Ryazanov AG.

J Biol Chem. 2016 Sep 9;291(37):19545-57. doi: 10.1074/jbc.M116.724856. Epub 2016 Jul 27.

6.

Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor.

Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA.

Nat Commun. 2016 Jun 30;7:12038. doi: 10.1038/ncomms12038.

7.

Hypoplastic left heart syndrome and the nutmeg lung pattern in utero: a cause and effect relationship or prognostic indicator?

Saul D, Degenhardt K, Iyoob SD, Surrey LF, Johnson AM, Johnson MP, Rychik J, Victoria T.

Pediatr Radiol. 2016 Apr;46(4):483-9. doi: 10.1007/s00247-015-3514-6. Epub 2015 Dec 21.

PMID:
26691156
8.

Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease.

Varvel NH, Grathwohl SA, Degenhardt K, Resch C, Bosch A, Jucker M, Neher JJ.

J Exp Med. 2015 Oct 19;212(11):1803-9. doi: 10.1084/jem.20150478. Epub 2015 Oct 12.

9.

Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.

Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S.

Dev Biol. 2015 Nov 15;407(2):195-210. doi: 10.1016/j.ydbio.2015.09.016. Epub 2015 Oct 3.

10.

Persistence of Aβ seeds in APP null mouse brain.

Ye L, Fritschi SK, Schelle J, Obermüller U, Degenhardt K, Kaeser SA, Eisele YS, Walker LC, Baumann F, Staufenbiel M, Jucker M.

Nat Neurosci. 2015 Nov;18(11):1559-61. doi: 10.1038/nn.4117. Epub 2015 Sep 9.

PMID:
26352792
11.

Maternal hyperoxygenation improves left heart filling in fetuses with atrial septal aneurysm causing impediment to left ventricular inflow.

Channing A, Szwast A, Natarajan S, Degenhardt K, Tian Z, Rychik J.

Ultrasound Obstet Gynecol. 2015 Jun;45(6):664-9. doi: 10.1002/uog.14688. Epub 2015 May 4.

12.

Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis.

Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S.

Dev Biol. 2014 Nov 15;395(2):232-44. doi: 10.1016/j.ydbio.2014.09.014. Epub 2014 Sep 19.

13.

The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK.

Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H.

Front Pharmacol. 2013 Nov 18;4:141. doi: 10.3389/fphar.2013.00141. eCollection 2013.

14.

Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections.

Degenhardt K, Singh MK, Aghajanian H, Massera D, Wang Q, Li J, Li L, Choi C, Yzaguirre AD, Francey LJ, Gallant E, Krantz ID, Gruber PJ, Epstein JA.

Nat Med. 2013 Jun;19(6):760-5. doi: 10.1038/nm.3185. Epub 2013 May 12.

15.

New approaches under development: cardiovascular embryology applied to heart disease.

Degenhardt K, Singh MK, Epstein JA.

J Clin Invest. 2013 Jan;123(1):71-4. doi: 10.1172/JCI62884. Epub 2013 Jan 2. Review.

16.

Effect of changes in the deuterium content of drinking water on the hydrogen isotope ratio of urinary steroids in the context of sports drug testing.

Piper T, Degenhardt K, Federherr E, Thomas A, Thevis M, Saugy M.

Anal Bioanal Chem. 2013 Mar;405(9):2911-21. doi: 10.1007/s00216-012-6504-7. Epub 2012 Nov 6.

PMID:
23128907
17.

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.

Martino JJ, Wall BA, Mastrantoni E, Wilimczyk BJ, La Cava SN, Degenhardt K, White E, Chen S.

Oncogene. 2013 Sep 12;32(37):4366-76. doi: 10.1038/onc.2012.471. Epub 2012 Oct 22.

18.

Multimodal imaging in the prenatal diagnosis of tuberous sclerosis complex.

Gusman M, Servaes S, Feygin T, Degenhardt K, Epelman M.

Case Rep Pediatr. 2012;2012:925646. doi: 10.1155/2012/925646. Epub 2012 Oct 2.

19.
20.

Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells.

Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ.

Dev Cell. 2012 Mar 13;22(3):639-50. doi: 10.1016/j.devcel.2012.01.012.

21.

Autophagy and transporter-based multi-drug resistance.

Kumar P, Zhang DM, Degenhardt K, Chen ZS.

Cells. 2012 Aug 23;1(3):558-75. doi: 10.3390/cells1030558.

22.

Design and synthesis of N-substituted indazole-3-carboxamides as poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors(†).

Patel MR, Pandya KG, Lau-Cam CA, Singh S, Pino MA, Billack B, Degenhardt K, Talele TT.

Chem Biol Drug Des. 2012 Apr;79(4):488-96. doi: 10.1111/j.1747-0285.2011.01302.x. Epub 2012 Jan 30.

PMID:
22177599
23.

Hyperoxia sensing: from molecular mechanisms to significance in disease.

Gore A, Muralidhar M, Espey MG, Degenhardt K, Mantell LL.

J Immunotoxicol. 2010 Oct-Dec;7(4):239-54. doi: 10.3109/1547691X.2010.492254. Epub 2010 Jun 29. Review.

PMID:
20586583
24.

Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine staining.

Degenhardt K, Wright AC, Horng D, Padmanabhan A, Epstein JA.

Circ Cardiovasc Imaging. 2010 May;3(3):314-22. doi: 10.1161/CIRCIMAGING.109.918482. Epub 2010 Feb 27.

25.

Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions.

Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA.

Dev Biol. 2010 Mar 15;339(2):519-27. doi: 10.1016/j.ydbio.2009.12.030. Epub 2010 Jan 4.

26.

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.

Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA.

Dev Biol. 2009 Jan 1;325(1):82-93. doi: 10.1016/j.ydbio.2008.09.031. Epub 2008 Oct 17.

27.

Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.

Mathew R, Degenhardt K, Haramaty L, Karp CM, White E.

Methods Enzymol. 2008;446:77-106. doi: 10.1016/S0076-6879(08)01605-4.

PMID:
18603117
28.

Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression.

Karp CM, Tan TT, Mathew R, Nelson D, Mukherjee C, Degenhardt K, Karantza-Wadsworth V, White E.

Cancer Res. 2008 Jun 1;68(11):4105-15. doi: 10.1158/0008-5472.CAN-07-6814.

29.

Cre reporter mouse expressing a nuclear localized fusion of GFP and beta-galactosidase reveals new derivatives of Pax3-expressing precursors.

Stoller JZ, Degenhardt KR, Huang L, Zhou DD, Lu MM, Epstein JA.

Genesis. 2008 Apr;46(4):200-4. doi: 10.1002/dvg.20384.

30.

[Chronological age of patients with Turner syndrome at diagnosis].

Simm D, Degenhardt K, Gerdemann C, Völkl TM, Rauch A, Dörr HG.

Klin Padiatr. 2008 Jan-Feb;220(1):16-20. Epub 2007 Dec 20. German.

PMID:
18095252
31.

Induction of apoptosis by diterpenes from the soft coral Xenia elongata.

Andrianasolo EH, Haramaty L, Degenhardt K, Mathew R, White E, Lutz R, Falkowski P.

J Nat Prod. 2007 Oct;70(10):1551-7. Epub 2007 Sep 28.

32.

Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist.

Simmons MJ, Fan G, Zong WX, Degenhardt K, White E, Gélinas C.

Oncogene. 2008 Feb 28;27(10):1421-8. Epub 2007 Sep 3.

33.

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.

Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ.

EMBO J. 2007 Jun 20;26(12):2856-67. Epub 2007 May 24.

34.

Autophagy suppresses tumor progression by limiting chromosomal instability.

Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K, Chen G, Jin S, White E.

Genes Dev. 2007 Jun 1;21(11):1367-81. Epub 2007 May 17. Erratum in: Genes Dev. 2007 Jul 1;21(13):1701.

35.

NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition.

Shimazu T, Degenhardt K, Nur-E-Kamal A, Zhang J, Yoshida T, Zhang Y, Mathew R, White E, Inouye M.

Genes Dev. 2007 Apr 15;21(8):929-41. Epub 2007 Apr 2.

36.

Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation.

Jiang M, Pabla N, Murphy RF, Yang T, Yin XM, Degenhardt K, White E, Dong Z.

J Biol Chem. 2007 Jan 26;282(4):2636-45. Epub 2006 Nov 27.

37.

A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis.

Degenhardt K, White E.

Clin Cancer Res. 2006 Sep 15;12(18):5298-304. Review.

38.

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.

Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gélinas C, Fan Y, Nelson DA, Jin S, White E.

Cancer Cell. 2006 Jul;10(1):51-64.

39.

Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes.

Marín YE, Namkoong J, Shin SS, Raines J, Degenhardt K, White E, Chen S.

Neuropharmacology. 2005;49 Suppl 1:70-9.

PMID:
16040064
40.

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

Tan TT, Degenhardt K, Nelson DA, Beaudoin B, Nieves-Neira W, Bouillet P, Villunger A, Adams JM, White E.

Cancer Cell. 2005 Mar;7(3):227-38.

41.

Cardiovascular anomalies in children and young adults with Ullrich-Turner syndrome the Erlangen experience.

Völkl TM, Degenhardt K, Koch A, Simm D, Dörr HG, Singer H.

Clin Cardiol. 2005 Feb;28(2):88-92.

42.

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis.

Nelson DA, Tan TT, Rabson AB, Anderson D, Degenhardt K, White E.

Genes Dev. 2004 Sep 1;18(17):2095-107. Epub 2004 Aug 16.

43.

ASAP, a novel protein complex involved in RNA processing and apoptosis.

Schwerk C, Prasad J, Degenhardt K, Erdjument-Bromage H, White E, Tempst P, Kidd VJ, Manley JL, Lahti JM, Reinberg D.

Mol Cell Biol. 2003 Apr;23(8):2981-90.

44.

Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release.

Mikhailov V, Mikhailova M, Degenhardt K, Venkatachalam MA, White E, Saikumar P.

J Biol Chem. 2003 Feb 14;278(7):5367-76. Epub 2002 Nov 25.

45.

BAX and BAK mediate p53-independent suppression of tumorigenesis.

Degenhardt K, Chen G, Lindsten T, White E.

Cancer Cell. 2002 Sep;2(3):193-203.

46.

Pathways used by adenovirus E1B 19K to inhibit apoptosis.

Degenhardt K, Perez D, White E.

Symp Soc Exp Biol. 2000;52:241-51. Review. No abstract available.

PMID:
12090012
47.

Bak and Bax function to limit adenovirus replication through apoptosis induction.

Cuconati A, Degenhardt K, Sundararajan R, Anschel A, White E.

J Virol. 2002 May;76(9):4547-58.

48.

Bax and Bak independently promote cytochrome C release from mitochondria.

Degenhardt K, Sundararajan R, Lindsten T, Thompson C, White E.

J Biol Chem. 2002 Apr 19;277(16):14127-34. Epub 2002 Feb 8.

49.

Cellular and cis-regulation of En-2 expression in the mandibular arch.

Degenhardt K, Rentschler S, Fishman G, Sassoon DA.

Mech Dev. 2002 Feb;111(1-2):125-36.

50.

Visualization and functional characterization of the developing murine cardiac conduction system.

Rentschler S, Vaidya DM, Tamaddon H, Degenhardt K, Sassoon D, Morley GE, Jalife J, Fishman GI.

Development. 2001 May;128(10):1785-92.

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