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Items: 1 to 50 of 336

1.

Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer.

Ongkeko WM, Burton D, Kiang A, Abhold E, Kuo SZ, Rahimy E, Yang M, Hoffman RM, Wang-Rodriguez J, Deftos LJ.

PLoS One. 2014 Jan 22;9(1):e85803. doi: 10.1371/journal.pone.0085803. eCollection 2014.

2.

Deletion of the gene encoding calcitonin and calcitonin gene-related peptide α does not affect the outcome of severe infection in mice.

Tuvim MJ, Clement CG, Huang ES, Cote GJ, Evans SE, Lei X, Deftos LJ, Gagel RF, Dickey BF.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):151-5. doi: 10.1165/rcmb.2012-0489OC.

3.

Hypercalcemia in disseminated coccidioidomycosis: expression of parathyroid hormone-related peptide is characteristic of granulomatous inflammation.

Fierer J, Burton DW, Haghighi P, Deftos LJ.

Clin Infect Dis. 2012 Oct;55(7):e61-6. doi: 10.1093/cid/cis536. Epub 2012 Jun 5.

PMID:
22670039
4.

PTH/PTHrP and vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection.

Muehleisen B, Bikle DD, Aguilera C, Burton DW, Sen GL, Deftos LJ, Gallo RL.

Sci Transl Med. 2012 May 23;4(135):135ra66. doi: 10.1126/scitranslmed.3003759.

5.

Courts complicate industry-academia ties.

Deftos LJ.

Science. 2011 Aug 12;333(6044):823. doi: 10.1126/science.333.6044.823-b. No abstract available.

PMID:
21835999
6.

Prognostic implications of parathyroid hormone-related protein in males and females with non--small-cell lung cancer.

Montgrain PR, Deftos LJ, Arenberg D, Tipps A, Quintana R, Carskadon S, Hastings RH.

Clin Lung Cancer. 2011 May;12(3):197-205. doi: 10.1016/j.cllc.2011.03.018. Epub 2011 Apr 24.

PMID:
21663864
7.

Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis.

Grzesiak JJ, Tran Cao HS, Burton DW, Kaushal S, Vargas F, Clopton P, Snyder CS, Deftos LJ, Hoffman RM, Bouvet M.

Int J Cancer. 2011 Dec 15;129(12):2905-15. doi: 10.1002/ijc.25942. Epub 2011 Apr 13.

8.

Concurrent primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with multiple endocrine neoplasia type 1.

Milanesi A, Yu R, Geller SA, Burton D, Deftos LJ, Wolin EM.

Pancreas. 2011 May;40(4):634-7. doi: 10.1097/MPA.0b013e318214f65e.

PMID:
21483254
9.

PTHrP stimulates prostate cancer cell growth and upregulates aldo-keto reductase 1C3.

Downs TM, Burton DW, Araiza FL, Hastings RH, Deftos LJ.

Cancer Lett. 2011 Jul 1;306(1):52-9. doi: 10.1016/j.canlet.2011.02.027. Epub 2011 Mar 27.

PMID:
21444150
10.

Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.

Hastings RH, Burton DW, Nefzi A, Montgrain PR, Quintana R, Deftos LJ.

Cancer Biol Ther. 2010 Nov 15;10(10):1067-75. doi: 10.4161/cbt.10.10.13374. Epub 2010 Nov 15.

PMID:
20890111
11.

Cell cycle actions of parathyroid hormone-related protein in non-small cell lung carcinoma.

Hastings RH, Montgrain PR, Quintana R, Rascon Y, Deftos LJ, Healy E.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L578-85. doi: 10.1152/ajplung.90560.2008. Epub 2009 Jul 24.

12.

Parathyroid hormone-related protein varies with sex and androgen status in nonsmall cell lung cancer.

Montgrain PR, Quintana R, Rascon Y, Burton DW, Deftos LJ, Casillas A, Hastings RH.

Cancer. 2007 Sep 15;110(6):1313-20.

13.

Incidental finding of metastatic papillary thyroid carcinoma in a patient with primary hyperparathyroidism.

Lee JK, Obrzut SL, Yi ES, Deftos LJ, Bouvet M.

Endocr Pract. 2007 Jul-Aug;13(4):380-3.

PMID:
17669714
14.

Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells.

Grzesiak JJ, Smith KC, Burton DW, Deftos LJ, Bouvet M.

Surgery. 2007 Jun;141(6):804-14. Epub 2007 May 4.

15.

Congenital craniopharyngioma and hypercalcemia induced by parathyroid hormone-related protein.

Brown JL, Burton DW, Deftos LJ, Smith AA, Pincus DW, Haller MJ.

Endocr Pract. 2007 Jan-Feb;13(1):67-71.

PMID:
17360305
16.

Causes of hypercalcemia in a population of military veterans in the United States.

Newman EM, Bouvet M, Borgehi S, Herold DA, Deftos LJ.

Endocr Pract. 2006 Sep-Oct;12(5):535-41.

PMID:
17002928
17.

Combination therapy for osteoporosis: a counter-regulatory conundrum.

Deftos LJ.

Nat Clin Pract Rheumatol. 2006 Feb;2(2):64-5. No abstract available.

PMID:
16932655
18.

Games of hormones: the para-endocrinology of sport.

Deftos LJ.

Endocr Pract. 2006 Jul-Aug;12(4):472-4. No abstract available.

PMID:
16901804
19.

Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells.

Grzesiak JJ, Smith KC, Chalberg C, Burton DW, Deftos LJ, Bouvet M.

Int J Gastrointest Cancer. 2005;36(3):131-46.

PMID:
16720909
20.

The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model.

Yang M, Burton DW, Geller J, Hillegonds DJ, Hastings RH, Deftos LJ, Hoffman RM.

Clin Cancer Res. 2006 Apr 15;12(8):2602-6.

21.

Identification of DU 145 prostate cancer cell proteins that bind to the carboxy-terminal peptide of human PTHrP in vitro.

Grzesiak JJ, Burton DW, Deftos LJ, Bouvet M.

Peptides. 2006 Jul;27(7):1898-901. Epub 2006 Mar 2.

PMID:
16513210
23.

Sex-specific survival advantage with parathyroid hormone-related protein in non-small cell lung carcinoma patients.

Hastings RH, Laux AM, Casillas A, Xu R, Lukas Z, Ernstrom K, Deftos LJ.

Clin Cancer Res. 2006 Jan 15;12(2):499-506. Erratum in: Clin Cancer Res. 2006 Jul 1;12(13):4130.

24.

A carboxyl leucine-rich region of parathyroid hormone-related protein is critical for nuclear export.

Pache JC, Burton DW, Deftos LJ, Hastings RH.

Endocrinology. 2006 Feb;147(2):990-8. Epub 2005 Nov 17.

PMID:
16293661
25.

Hypercalcemia and local production of parathyroid hormone-related protein by a perisellar rhabdomyosarcoma after remote pituitary irradiation.

Florez JC, Burton DW, Arnell PM, Deftos LJ, Klibanski A.

Endocr Pract. 2005 May-Jun;11(3):184-9.

PMID:
16239205
26.

41Ca and accelerator mass spectrometry to monitor calcium metabolism in end stage renal disease patients.

Fitzgerald RL, Hillegonds DJ, Burton DW, Griffin TL, Mullaney S, Vogel JS, Deftos LJ, Herold DA.

Clin Chem. 2005 Nov;51(11):2095-102. Epub 2005 Sep 1.

27.

Treatment of Paget's disease--taming the wild osteoclast.

Deftos LJ.

N Engl J Med. 2005 Sep 1;353(9):872-5. No abstract available.

PMID:
16135831
28.

Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression.

Burton DW, Foster M, Johnson KA, Hiramoto M, Deftos LJ, Terkeltaub R.

Osteoarthritis Cartilage. 2005 May;13(5):395-404.

29.

Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro.

Grzesiak JJ, Smith KC, Chalberg C, Truong C, Burton DW, Deftos LJ, Bouvet M.

Endocrinology. 2005 Aug;146(8):3567-76. Epub 2005 May 5.

PMID:
15878959
30.

Direct evidence that PTHrP expression promotes prostate cancer progression in bone.

Deftos LJ, Barken I, Burton DW, Hoffman RM, Geller J.

Biochem Biophys Res Commun. 2005 Feb 11;327(2):468-72.

PMID:
15629138
31.

GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells.

Grzesiak JJ, Smith KC, Burton DW, Deftos LJ, Bouvet M.

Int J Cancer. 2005 Apr 20;114(4):522-30.

32.

Parathyroid hormone-related protein expression is correlated with clinical course in patients with glial tumors.

Pardo FS, Lien WW, Fox HS, Efird JT, Aguilera JA, Burton DW, Deftos LJ.

Cancer. 2004 Dec 1;101(11):2622-8.

33.

Monitoring of skeletal progression of prostate cancer by GFP imaging, X-ray, and serum OPG and PTHrP.

Burton DW, Geller J, Yang M, Jiang P, Barken I, Hastings RH, Hoffman RM, Deftos LJ.

Prostate. 2005 Feb 15;62(3):275-81.

PMID:
15389781
34.

Should serum calcitonin be routinely measured in patients with thyroid nodules--will the law answer before endocrinologists do?

Deftos LJ.

J Clin Endocrinol Metab. 2004 Sep;89(9):4768-9; author reply 4769-70. No abstract available.

PMID:
15356093
35.

Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A.

Hastings RH, Araiza F, Burton DW, Bedley M, Deftos LJ.

Am J Physiol Cell Physiol. 2004 Dec;287(6):C1616-22. Epub 2004 Jul 28.

36.

The extracellular matrix differentially regulates the expression of PTHrP and the PTH/PTHrP receptor in FG pancreatic cancer cells.

Grzesiak JJ, Clopton P, Chalberg C, Smith K, Burton DW, Silletti S, Moossa AR, Deftos LJ, Bouvet M.

Pancreas. 2004 Aug;29(2):85-92.

PMID:
15257098
37.

Role of parathyroid hormone-related protein in lung cancer cell survival.

Hastings RH, Araiza F, Burton DW, Deftos LJ.

Chest. 2004 May;125(5 Suppl):150S. No abstract available.

PMID:
15136475
38.

Metachronous double parathyroid adenomas involving two different cell types: chief cell and oxyphil cell.

Zhou W, Katz MH, Deftos LJ, Snyder CS, Baird S, Bouvet M.

Endocr Pract. 2003 Nov-Dec;9(6):522-5.

PMID:
14715480
39.

Ethics and genetics.

Deftos LJ.

N Engl J Med. 2003 Nov 6;349(19):1870-2; author reply 1870-2. No abstract available.

PMID:
14606468
40.

Amino-terminal and midmolecule parathyroid hormone-related protein, phosphatidylcholine, and type II cell proliferation in silica-injured lung.

Hastings RH, Quintana RA, Sandoval R, Burton DW, Deftos LJ.

Am J Physiol Lung Cell Mol Physiol. 2003 Dec;285(6):L1312-22. Epub 2003 Aug 15.

41.

Parathyroid hormone-related protein ameliorates death receptor-mediated apoptosis in lung cancer cells.

Hastings RH, Araiza F, Burton DW, Zhang L, Bedley M, Deftos LJ.

Am J Physiol Cell Physiol. 2003 Dec;285(6):C1429-36. Epub 2003 Aug 13.

42.

Thymic parathyroid carcinoma and postoperative hungry bone syndrome.

Chandran M, Deftos LJ, Stuenkel CA, Haghighi P, Orloff LA.

Endocr Pract. 2003 Mar-Apr;9(2):152-6. Review.

PMID:
12917079
43.

Proapoptotic effects of parathyroid hormone-related protein in type II pneumocytes.

Hastings RH, Quintana RA, Sandoval R, Duey D, Rascon Y, Burton DW, Deftos LJ.

Am J Respir Cell Mol Biol. 2003 Dec;29(6):733-42. Epub 2003 Jun 5.

PMID:
12791677
44.

Stability of a transdermal salmon calcitonin formulation.

Chang SL, Hofmann GA, Zhang L, Deftos LJ, Banga AK.

Drug Deliv. 2003 Jan-Mar;10(1):41-5.

PMID:
12554363
45.

Mass spectrometric immunoassay for parathyroid hormone-related protein.

Lu CM, Burton WD, Fitzgerald RL, Deftos LJ, Buchholz BA, Vogel JS, Herold DA.

Anal Chem. 2002 Nov 1;74(21):5507-12.

PMID:
12433080
46.

Parathyroid hormone-related protein and lung injury.

Hastings RH, Deftos LJ.

Chest. 2002 Oct;122(4):1494; author reply 1494-5. No abstract available.

PMID:
12377889
47.

Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor.

Bakre MM, Zhu Y, Yin H, Burton DW, Terkeltaub R, Deftos LJ, Varner JA.

Nat Med. 2002 Sep;8(9):995-1003. Epub 2002 Aug 19.

PMID:
12185361
48.

Parathyroid hormone-related protein-(38-64) regulates lung cell proliferation after silica injury.

Hastings RH, Asirvatham A, Quintana R, Sandoval R, Dutta R, Burton DW, Deftos LJ.

Am J Physiol Lung Cell Mol Physiol. 2002 Jul;283(1):L12-21.

49.

Hypercalcemia in malignant and inflammatory diseases.

Deftos LJ.

Endocrinol Metab Clin North Am. 2002 Mar;31(1):141-58. Review.

PMID:
12055985
50.

Parathyroid hormone-related protein response to hyperoxic lung injury.

Hastings RH, Ryan RM, D'Angio CT, Holm BA, Patel A, Quintana R, Biederman E, Burton DW, Deftos LJ.

Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1198-208.

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