Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 97

1.

Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration.

Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, Neve RL, Dietz DM, Nestler EJ.

J Neurosci. 2019 May 15. pii: 0024-19. doi: 10.1523/JNEUROSCI.0024-19.2019. [Epub ahead of print]

PMID:
31092585
2.

Modeling ErbB2-p130Cas interaction to design new potential anticancer agents.

Costamagna A, Rossi Sebastiano M, Natalini D, Simoni M, Valabrega G, Defilippi P, Visentin S, Ermondi G, Turco E, Caron G, Cabodi S.

Sci Rep. 2019 Feb 28;9(1):3089. doi: 10.1038/s41598-019-39510-w.

3.

Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers.

Calorio C, Gavello D, Guarina L, Salio C, Sassoè-Pognetto M, Riganti C, Bianchi FT, Hofer NT, Tuluc P, Obermair GJ, Defilippi P, Balzac F, Turco E, Bett GC, Rasmusson RL, Carbone E.

J Physiol. 2019 Mar;597(6):1705-1733. doi: 10.1113/JP277487. Epub 2019 Jan 28.

PMID:
30629744
4.

Correction to: Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation.

Del Pilar Camacho Leal M, Costamagna A, Tassone B, Saoncella S, Simoni M, Natalini D, Dadone A, Sciortino M, Turco E, Defilippi P, Calautti E, Cabodi S.

Cell Commun Signal. 2018 Nov 26;16(1):90. doi: 10.1186/s12964-018-0296-0.

5.

Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation.

Camacho Leal MDP, Costamagna A, Tassone B, Saoncella S, Simoni M, Natalini D, Dadone A, Sciortino M, Turco E, Defilippi P, Calautti E, Cabodi S.

Cell Commun Signal. 2018 Nov 3;16(1):73. doi: 10.1186/s12964-018-0289-z. Erratum in: Cell Commun Signal. 2018 Nov 26;16(1):90.

6.

Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, di Cantogno LV, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2018 Mar 30;9:16203. doi: 10.1038/ncomms16203.

7.

p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits.

Russo I, Gavello D, Menna E, Vandael D, Veglia C, Morello N, Corradini I, Focchi E, Alfieri A, Angelini C, Bianchi FT, Morellato A, Marcantoni A, Sassoè-Pognetto M, Ottaviani MM, Yekhlef L, Giustetto M, Taverna S, Carabelli V, Matteoli M, Carbone E, Turco E, Defilippi P.

Cereb Cortex. 2019 Jan 1;29(1):91-105. doi: 10.1093/cercor/bhx306.

8.

Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells.

Bagnato P, Castagnino A, Cortese K, Bono M, Grasso S, Bellese G, Daniele T, Lundmark R, Defilippi P, Castagnola P, Tacchetti C.

Oncotarget. 2017 May 8;8(36):60109-60122. doi: 10.18632/oncotarget.17686. eCollection 2017 Sep 1.

9.

Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders.

Alfieri A, Sorokina O, Adrait A, Angelini C, Russo I, Morellato A, Matteoli M, Menna E, Boeri Erba E, McLean C, Armstrong JD, Ala U, Buxbaum JD, Brusco A, Couté Y, De Rubeis S, Turco E, Defilippi P.

Front Mol Neurosci. 2017 Jun 30;10:212. doi: 10.3389/fnmol.2017.00212. eCollection 2017.

10.

Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion.

Sciortino M, Camacho-Leal MDP, Orso F, Grassi E, Costamagna A, Provero P, Tam W, Turco E, Defilippi P, Taverna D, Cabodi S.

Sci Rep. 2017 Apr 25;7(1):1145. doi: 10.1038/s41598-017-01332-z.

11.

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.

Becchetti A, Crescioli S, Zanieri F, Petroni G, Mercatelli R, Coppola S, Gasparoli L, D'Amico M, Pillozzi S, Crociani O, Stefanini M, Fiore A, Carraresi L, Morello V, Manoli S, Brizzi MF, Ricci D, Rinaldi M, Masi A, Schmidt T, Quercioli F, Defilippi P, Arcangeli A.

Sci Signal. 2017 Apr 4;10(473). pii: eaaf3236. doi: 10.1126/scisignal.aaf3236.

PMID:
28377405
12.

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, Verdun di Cantogno L, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2017 Mar 16;8:14797. doi: 10.1038/ncomms14797. Erratum in: Nat Commun. 2018 Mar 30;9:16203.

13.

Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.

Principe M, Borgoni S, Cascione M, Chattaragada MS, Ferri-Borgogno S, Capello M, Bulfamante S, Chapelle J, Di Modugno F, Defilippi P, Nisticò P, Cappello P, Riganti C, Leporatti S, Novelli F.

J Hematol Oncol. 2017 Jan 13;10(1):16. doi: 10.1186/s13045-016-0385-8.

14.

Histone arginine methylation in cocaine action in the nucleus accumbens.

Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, Cates H, Lobo MK, Dietz D, Allis CD, Guccione E, Turecki G, Defilippi P, Neve RL, Hurd YL, Shen L, Nestler EJ.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9623-8. doi: 10.1073/pnas.1605045113. Epub 2016 Aug 9.

15.

p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy.

Bisaro B, Sciortino M, Colombo S, Camacho Leal MP, Costamagna A, Castellano I, Montemurro F, Rossi V, Valabrega G, Turco E, Defilippi P, Cabodi S.

Oncotarget. 2016 Jan 26;7(4):4442-53. doi: 10.18632/oncotarget.6710.

16.

New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia.

Panuzzo C, Volpe G, Cibrario Rocchietti E, Casnici C, Crotta K, Crivellaro S, Carrà G, Lorenzatti R, Peracino B, Torti D, Morotti A, Camacho-Leal MP, Defilippi P, Marelli O, Saglio G.

Oncoscience. 2015 Nov 11;2(10):880-91. eCollection 2015.

17.

Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome.

Rea K, Pinciroli P, Sensi M, Alciato F, Bisaro B, Lozneanu L, Raspagliesi F, Centritto F, Cabodi S, Defilippi P, Avanzi GC, Canevari S, Tomassetti A.

Oncotarget. 2015 Oct 13;6(31):30859-75. doi: 10.18632/oncotarget.5087.

18.

p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis.

Camacho Leal Mdel P, Sciortino M, Tornillo G, Colombo S, Defilippi P, Cabodi S.

Gene. 2015 May 10;562(1):1-7. doi: 10.1016/j.gene.2015.02.027. Epub 2015 Feb 27. Review.

PMID:
25727852
19.

Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, Sharma V, Papale A, Pozzi D, Defilippi P, Meier JC, Brambilla R, Turco E, Rosenblum K, Wanker EE, Ziv NE, Menna E, Matteoli M.

Cell Death Differ. 2015 Sep;22(9):1425-36. doi: 10.1038/cdd.2014.227. Epub 2015 Feb 13.

20.

Cas proteins: dodgy scaffolding in breast cancer.

Tornillo G, Defilippi P, Cabodi S.

Breast Cancer Res. 2014;16(5):443. Review.

21.

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.

Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P.

J Neurosci. 2014 Jan 22;34(4):1542-53. doi: 10.1523/JNEUROSCI.2341-13.2014.

22.
23.

SNAP-25 regulates spine formation through postsynaptic binding to p140Cap.

Tomasoni R, Repetto D, Morini R, Elia C, Gardoni F, Di Luca M, Turco E, Defilippi P, Matteoli M.

Nat Commun. 2013;4:2136. doi: 10.1038/ncomms3136.

24.

Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties.

Sharma N, Repetto D, Aramu S, Grasso S, Russo I, Fiorentino A, Mello-Grand M, Cabodi S, Singh V, Chiorino G, Turco E, Stefano PD, Defilippi P.

Am J Cancer Res. 2013 Jun 20;3(3):290-301. Print 2013.

25.

Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells.

Pincini A, Tornillo G, Orso F, Sciortino M, Bisaro B, Leal Mdel P, Lembo A, Brizzi MF, Turco E, De Pittà C, Provero P, Medico E, Defilippi P, Taverna D, Cabodi S.

Cell Cycle. 2013 Aug 1;12(15):2409-22. doi: 10.4161/cc.25415. Epub 2013 Jun 28.

26.

The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase.

Sciacovelli M, Guzzo G, Morello V, Frezza C, Zheng L, Nannini N, Calabrese F, Laudiero G, Esposito F, Landriscina M, Defilippi P, Bernardi P, Rasola A.

Cell Metab. 2013 Jun 4;17(6):988-99. doi: 10.1016/j.cmet.2013.04.019.

27.

p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity.

Tornillo G, Elia AR, Castellano I, Spadaro M, Bernabei P, Bisaro B, Camacho-Leal Mdel P, Pincini A, Provero P, Sapino A, Turco E, Defilippi P, Cabodi S.

Stem Cells. 2013 Jul;31(7):1422-33. doi: 10.1002/stem.1403.

28.

Mapping of p140Cap phosphorylation sites: the EPLYA and EGLYA motifs have a key role in tyrosine phosphorylation and Csk binding, and are substrates of the Abl kinase.

Repetto D, Aramu S, Boeri Erba E, Sharma N, Grasso S, Russo I, Jensen ON, Cabodi S, Turco E, Di Stefano P, Defilippi P.

PLoS One. 2013;8(1):e54931. doi: 10.1371/journal.pone.0054931. Epub 2013 Jan 31.

29.

p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.

Camacho Leal Mdel P, Pincini A, Tornillo G, Fiorito E, Bisaro B, Di Luca E, Turco E, Defilippi P, Cabodi S.

PLoS One. 2012;7(12):e49817. doi: 10.1371/journal.pone.0049817. Epub 2012 Dec 11.

30.

p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.

Bisaro B, Montani M, Konstantinidou G, Marchini C, Pietrella L, Iezzi M, Galiè M, Orso F, Camporeale A, Colombo SM, Di Stefano P, Tornillo G, Camacho-Leal MP, Turco E, Taverna D, Cabodi S, Amici A, Defilippi P.

Breast Cancer Res. 2012 Oct 26;14(5):R137. doi: 10.1186/bcr3342.

31.

Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche.

Brizzi MF, Tarone G, Defilippi P.

Curr Opin Cell Biol. 2012 Oct;24(5):645-51. doi: 10.1016/j.ceb.2012.07.001. Epub 2012 Aug 13. Review.

PMID:
22898530
32.

The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells.

Di Stefano P, Leal MP, Tornillo G, Bisaro B, Repetto D, Pincini A, Santopietro E, Sharma N, Turco E, Cabodi S, Defilippi P.

Am J Cancer Res. 2011;1(5):663-73. Epub 2011 May 2.

33.

p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.

Damiano L, Le Dévédec SE, Di Stefano P, Repetto D, Lalai R, Truong H, Xiong JL, Danen EH, Yan K, Verbeek FJ, De Luca E, Attanasio F, Buccione R, Turco E, van de Water B, Defilippi P.

Oncogene. 2012 Feb 2;31(5):624-33. doi: 10.1038/onc.2011.257. Epub 2011 Jul 4.

PMID:
21725361
34.

β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells.

Morello V, Cabodi S, Sigismund S, Camacho-Leal MP, Repetto D, Volante M, Papotti M, Turco E, Defilippi P.

Oncogene. 2011 Sep 29;30(39):4087-96. doi: 10.1038/onc.2011.107. Epub 2011 Apr 11.

35.

Integrin signalling adaptors: not only figurants in the cancer story.

Cabodi S, del Pilar Camacho-Leal M, Di Stefano P, Defilippi P.

Nat Rev Cancer. 2010 Dec;10(12):858-70. doi: 10.1038/nrc2967. Epub 2010 Nov 24. Review.

36.

p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1.

Tornillo G, Bisaro B, Camacho-Leal Mdel P, Galiè M, Provero P, Di Stefano P, Turco E, Defilippi P, Cabodi S.

Eur J Cell Biol. 2011 Feb-Mar;90(2-3):237-48. doi: 10.1016/j.ejcb.2010.09.002. Epub 2010 Oct 18.

37.

Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis.

Uberti B, Dentelli P, Rosso A, Defilippi P, Brizzi MF.

Oncogene. 2010 Dec 16;29(50):6581-90. doi: 10.1038/onc.2010.384. Epub 2010 Aug 30.

PMID:
20802515
38.

Integrins and signal transduction.

Cabodi S, Di Stefano P, Leal Mdel P, Tinnirello A, Bisaro B, Morello V, Damiano L, Aramu S, Repetto D, Tornillo G, Defilippi P.

Adv Exp Med Biol. 2010;674:43-54. Review.

PMID:
20549939
39.

p130Cas is an essential transducer element in ErbB2 transformation.

Cabodi S, Tinnirello A, Bisaro B, Tornillo G, del Pilar Camacho-Leal M, Forni G, Cojoca R, Iezzi M, Amici A, Montani M, Eva A, Di Stefano P, Muthuswamy SK, Tarone G, Turco E, Defilippi P.

FASEB J. 2010 Oct;24(10):3796-808. doi: 10.1096/fj.10-157347. Epub 2010 May 26.

PMID:
20505116
40.

p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.

Damiano L, Di Stefano P, Camacho Leal MP, Barba M, Mainiero F, Cabodi S, Tordella L, Sapino A, Castellano I, Canel M, Frame M, Turco E, Defilippi P.

Oncogene. 2010 Jun 24;29(25):3677-90. doi: 10.1038/onc.2010.128. Epub 2010 May 10.

PMID:
20453886
41.

p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling.

Belletti B, Pellizzari I, Berton S, Fabris L, Wolf K, Lovat F, Schiappacassi M, D'Andrea S, Nicoloso MS, Lovisa S, Sonego M, Defilippi P, Vecchione A, Colombatti A, Friedl P, Baldassarre G.

Mol Cell Biol. 2010 May;30(9):2229-40. doi: 10.1128/MCB.00723-09. Epub 2010 Mar 1.

42.

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC.

Neuron. 2009 Jan 15;61(1):85-100. doi: 10.1016/j.neuron.2008.11.013.

43.

Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression.

Cabodi S, Morello V, Masi A, Cicchi R, Broggio C, Distefano P, Brunelli E, Silengo L, Pavone F, Arcangeli A, Turco E, Tarone G, Moro L, Defilippi P.

J Cell Physiol. 2009 Feb;218(2):294-303. doi: 10.1002/jcp.21603.

PMID:
18844239
44.

Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.

Ito H, Atsuzawa K, Sudo K, Di Stefano P, Iwamoto I, Morishita R, Takei S, Semba R, Defilippi P, Asano T, Usuda N, Nagata K.

J Neurochem. 2008 Oct;107(1):61-72. doi: 10.1111/j.1471-4159.2008.05585.x. Epub 2008 Jul 24.

45.

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.

Di Stefano P, Damiano L, Cabodi S, Aramu S, Tordella L, Praduroux A, Piva R, Cavallo F, Forni G, Silengo L, Tarone G, Turco E, Defilippi P.

EMBO J. 2007 Jun 20;26(12):2843-55. Epub 2007 May 24.

46.

Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.

Boeri Erba E, Matthiesen R, Bunkenborg J, Schulze WX, Di Stefano P, Cabodi S, Tarone G, Defilippi P, Jensen ON.

J Proteome Res. 2007 Jul;6(7):2768-85. Epub 2007 May 25.

PMID:
17523611
47.

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.

Cancer Res. 2006 May 1;66(9):4672-80.

48.

p130Cas: a versatile scaffold in signaling networks.

Defilippi P, Di Stefano P, Cabodi S.

Trends Cell Biol. 2006 May;16(5):257-63. Epub 2006 Apr 3. Review.

PMID:
16581250
49.

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

Ambrogio C, Voena C, Manazza AD, Piva R, Riera L, Barberis L, Costa C, Tarone G, Defilippi P, Hirsch E, Boeri Erba E, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.

Blood. 2005 Dec 1;106(12):3907-16. Epub 2005 Aug 16. Erratum in: Blood. 2009 Sep 24;114(13):2851.

50.

The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization.

Dentelli P, Rosso A, Garbarino G, Calvi C, Lombard E, Di Stefano P, Defilippi P, Pegoraro L, Brizzi MF.

Oncogene. 2005 Sep 22;24(42):6394-405.

PMID:
16007196

Supplemental Content

Loading ...
Support Center