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Items: 12

1.

Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.

Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF.

Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. No abstract available.

2.

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

Hoang CQ, Hale MA, Azevedo-Pouly AC, Elsässer HP, Deering TG, Willet SG, Pan FC, Magnuson MA, Wright CV, Swift GH, MacDonald RJ.

Mol Cell Biol. 2016 Nov 28;36(24):3033-3047. Print 2016 Dec 15.

3.

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice.

Jiang M, Azevedo-Pouly AC, Deering TG, Hoang CQ, DiRenzo D, Hess DA, Konieczny SF, Swift GH, MacDonald RJ.

Mol Cell Biol. 2016 Nov 14;36(23):2945-2955. doi: 10.1128/MCB.00370-16. Print 2016 Dec 1.

4.

MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response.

Hess DA, Strelau KM, Karki A, Jiang M, Azevedo-Pouly AC, Lee AH, Deering TG, Hoang CQ, MacDonald RJ, Konieczny SF.

Mol Cell Biol. 2016 Nov 14;36(23):2931-2944. doi: 10.1128/MCB.00366-16. Print 2016 Dec 1.

5.

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.

Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC.

J Lipid Res. 2016 Jul;57(7):1231-42. doi: 10.1194/jlr.M067389. Epub 2016 May 2.

6.

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.

Hale MA, Swift GH, Hoang CQ, Deering TG, Masui T, Lee YK, Xue J, MacDonald RJ.

Development. 2014 Aug;141(16):3123-33. doi: 10.1242/dev.109405. Epub 2014 Jul 25.

7.

Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility.

Meredith DM, Borromeo MD, Deering TG, Casey BH, Savage TK, Mayer PR, Hoang C, Tung KC, Kumar M, Shen C, Swift GH, Macdonald RJ, Johnson JE.

Mol Cell Biol. 2013 Aug;33(16):3166-79. doi: 10.1128/MCB.00364-13. Epub 2013 Jun 10.

8.

Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro.

Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, LeCluyse EL, Blackman BR, Wamhoff BR.

Am J Physiol Cell Physiol. 2013 Jun 1;304(11):C1053-63. doi: 10.1152/ajpcell.00331.2012. Epub 2013 Mar 13.

9.

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure.

Evans-Molina C, Robbins RD, Kono T, Tersey SA, Vestermark GL, Nunemaker CS, Garmey JC, Deering TG, Keller SR, Maier B, Mirmira RG.

Mol Cell Biol. 2009 Apr;29(8):2053-67. doi: 10.1128/MCB.01179-08. Epub 2009 Feb 23.

10.

Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes.

Deering TG, Ogihara T, Trace AP, Maier B, Mirmira RG.

Diabetes. 2009 Jan;58(1):185-93. doi: 10.2337/db08-1150. Epub 2008 Nov 4.

11.

A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.

Babu DA, Deering TG, Mirmira RG.

Mol Genet Metab. 2007 Sep-Oct;92(1-2):43-55. Epub 2007 Jul 30. Review.

12.

Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1.

Francis J, Babu DA, Deering TG, Chakrabarti SK, Garmey JC, Evans-Molina C, Taylor DG, Mirmira RG.

Mol Endocrinol. 2006 Dec;20(12):3133-45. Epub 2006 Aug 10.

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