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Items: 1 to 50 of 120

1.

Iron-specific Signal Separation from within Heavy Metal Stained Biological Samples Using X-Ray Microtomography with Polychromatic Source and Energy-Integrating Detectors.

Katchalski T, Case T, Kim KY, Ramachandra R, Bushong EA, Deerinck TJ, Haberl MG, Mackey MR, Peltier S, Castillon GA, Fujikawa N, Lawrence AR, Ellisman MH.

Sci Rep. 2018 May 15;8(1):7553. doi: 10.1038/s41598-018-25099-z.

2.

Subgroup characteristics of marine methane-oxidizing ANME-2 archaea and their syntrophic partners revealed by integrated multimodal analytical microscopy.

McGlynn SE, Chadwick GL, O'Neill A, Mackey M, Thor A, Deerinck TJ, Ellisman MH, Orphan VJ.

Appl Environ Microbiol. 2018 Apr 6. pii: AEM.00399-18. doi: 10.1128/AEM.00399-18. [Epub ahead of print]

PMID:
29625978
3.

High-performance serial block-face SEM of nonconductive biological samples enabled by focal gas injection-based charge compensation.

Deerinck TJ, Shone TM, Bushong EA, Ramachandra R, Peltier ST, Ellisman MH.

J Microsc. 2018 May;270(2):142-149. doi: 10.1111/jmi.12667. Epub 2017 Dec 1.

PMID:
29194648
4.

Electron microscopy using the genetically encoded APEX2 tag in cultured mammalian cells.

Martell JD, Deerinck TJ, Lam SS, Ellisman MH, Ting AY.

Nat Protoc. 2017 Sep;12(9):1792-1816. doi: 10.1038/nprot.2017.065. Epub 2017 Aug 10.

5.

ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells.

Ou HD, Phan S, Deerinck TJ, Thor A, Ellisman MH, O'Shea CC.

Science. 2017 Jul 28;357(6349). pii: eaag0025. doi: 10.1126/science.aag0025.

6.

Activity-dependent trafficking of lysosomes in dendrites and dendritic spines.

Goo MS, Sancho L, Slepak N, Boassa D, Deerinck TJ, Ellisman MH, Bloodgood BL, Patrick GN.

J Cell Biol. 2017 Aug 7;216(8):2499-2513. doi: 10.1083/jcb.201704068. Epub 2017 Jun 19.

7.

Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.

Falkenberg CV, Azeloglu EU, Stothers M, Deerinck TJ, Chen Y, He JC, Ellisman MH, Hone JC, Iyengar R, Loew LM.

PLoS Comput Biol. 2017 Mar 16;13(3):e1005433. doi: 10.1371/journal.pcbi.1005433. eCollection 2017 Mar.

8.

Spines of the porcupine fish: Structure, composition, and mechanical properties.

Su FY, Bushong EA, Deerinck TJ, Seo K, Herrera S, Graeve OA, Kisailus D, Lubarda VA, McKittrick J.

J Mech Behav Biomed Mater. 2017 Sep;73:38-49. doi: 10.1016/j.jmbbm.2017.02.029. Epub 2017 Feb 28.

PMID:
28274703
9.

Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells.

Han S, Udeshi ND, Deerinck TJ, Svinkina T, Ellisman MH, Carr SA, Ting AY.

Cell Chem Biol. 2017 Mar 16;24(3):404-414. doi: 10.1016/j.chembiol.2017.02.002. Epub 2017 Feb 23.

10.

High resolution three-dimensional reconstruction of fibrotic skeletal muscle extracellular matrix.

Gillies AR, Chapman MA, Bushong EA, Deerinck TJ, Ellisman MH, Lieber RL.

J Physiol. 2017 Feb 15;595(4):1159-1171. doi: 10.1113/JP273376. Epub 2016 Dec 14.

11.

Deceleration of probe beam by stage bias potential improves resolution of serial block-face scanning electron microscopic images.

Bouwer JC, Deerinck TJ, Bushong E, Astakhov V, Ramachandra R, Peltier ST, Ellisman MH.

Adv Struct Chem Imaging. 2017;2(1):11. Epub 2016 Sep 15.

12.

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts.

Loh KH, Stawski PS, Draycott AS, Udeshi ND, Lehrman EK, Wilton DK, Svinkina T, Deerinck TJ, Ellisman MH, Stevens B, Carr SA, Ting AY.

Cell. 2016 Aug 25;166(5):1295-1307.e21. doi: 10.1016/j.cell.2016.07.041.

13.

A split horseradish peroxidase for the detection of intercellular protein-protein interactions and sensitive visualization of synapses.

Martell JD, Yamagata M, Deerinck TJ, Phan S, Kwa CG, Ellisman MH, Sanes JR, Ting AY.

Nat Biotechnol. 2016 Jul;34(7):774-80. doi: 10.1038/nbt.3563. Epub 2016 May 30.

14.

Corrigendum to 'Visualizing viral protein structures in cells using genetic probes for correlated light and electron microscopy' [Methods 90 (2015) 39-48].

Ou HD, Deerinck TJ, Bushong E, Ellisman MH, O'Shea CC.

Methods. 2016 Jul 15;104:206. doi: 10.1016/j.ymeth.2016.05.005. Epub 2016 May 21. No abstract available.

PMID:
27221672
15.

Click-EM for imaging metabolically tagged nonprotein biomolecules.

Ngo JT, Adams SR, Deerinck TJ, Boassa D, Rodriguez-Rivera F, Palida SF, Bertozzi CR, Ellisman MH, Tsien RY.

Nat Chem Biol. 2016 Jun;12(6):459-65. doi: 10.1038/nchembio.2076. Epub 2016 Apr 25.

16.

Evidence-based green algal genomics reveals marine diversity and ancestral characteristics of land plants.

van Baren MJ, Bachy C, Reistetter EN, Purvine SO, Grimwood J, Sudek S, Yu H, Poirier C, Deerinck TJ, Kuo A, Grigoriev IV, Wong CH, Smith RD, Callister SJ, Wei CL, Schmutz J, Worden AZ.

BMC Genomics. 2016 Mar 31;17:267. doi: 10.1186/s12864-016-2585-6.

17.

Design and synthesis of a minimal bacterial genome.

Hutchison CA 3rd, Chuang RY, Noskov VN, Assad-Garcia N, Deerinck TJ, Ellisman MH, Gill J, Kannan K, Karas BJ, Ma L, Pelletier JF, Qi ZQ, Richter RA, Strychalski EA, Sun L, Suzuki Y, Tsvetanova B, Wise KS, Smith HO, Glass JI, Merryman C, Gibson DG, Venter JC.

Science. 2016 Mar 25;351(6280):aad6253. doi: 10.1126/science.aad6253. Erratum in: ACS Chem Biol. 2016 May 20;11(5):1463.

PMID:
27013737
18.

Visualizing viral protein structures in cells using genetic probes for correlated light and electron microscopy.

Ou HD, Deerinck TJ, Bushong E, Ellisman MH, O'Shea CC.

Methods. 2015 Nov 15;90:39-48. doi: 10.1016/j.ymeth.2015.06.002. Epub 2015 Jun 9. Review.

19.

Designer diatom episomes delivered by bacterial conjugation.

Karas BJ, Diner RE, Lefebvre SC, McQuaid J, Phillips AP, Noddings CM, Brunson JK, Valas RE, Deerinck TJ, Jablanovic J, Gillard JT, Beeri K, Ellisman MH, Glass JI, Hutchison CA 3rd, Smith HO, Venter JC, Allen AE, Dupont CL, Weyman PD.

Nat Commun. 2015 Apr 21;6:6925. doi: 10.1038/ncomms7925.

20.

Correlative stochastic optical reconstruction microscopy and electron microscopy.

Kim D, Deerinck TJ, Sigal YM, Babcock HP, Ellisman MH, Zhuang X.

PLoS One. 2015 Apr 15;10(4):e0124581. doi: 10.1371/journal.pone.0124581. eCollection 2015.

21.

A workflow for the automatic segmentation of organelles in electron microscopy image stacks.

Perez AJ, Seyedhosseini M, Deerinck TJ, Bushong EA, Panda S, Tasdizen T, Ellisman MH.

Front Neuroanat. 2014 Nov 7;8:126. doi: 10.3389/fnana.2014.00126. eCollection 2014.

22.

Directed evolution of APEX2 for electron microscopy and proximity labeling.

Lam SS, Martell JD, Kamer KJ, Deerinck TJ, Ellisman MH, Mootha VK, Ting AY.

Nat Methods. 2015 Jan;12(1):51-4. doi: 10.1038/nmeth.3179. Epub 2014 Nov 24.

23.

Computational design of a red fluorophore ligase for site-specific protein labeling in living cells.

Liu DS, Nivón LG, Richter F, Goldman PJ, Deerinck TJ, Yao JZ, Richardson D, Phipps WS, Ye AZ, Ellisman MH, Drennan CL, Baker D, Ting AY.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4551-9. doi: 10.1073/pnas.1404736111. Epub 2014 Oct 13.

24.

Three-dimensional reconstruction of skeletal muscle extracellular matrix ultrastructure.

Gillies AR, Bushong EA, Deerinck TJ, Ellisman MH, Lieber RL.

Microsc Microanal. 2014 Dec;20(6):1835-40. doi: 10.1017/S1431927614013300. Epub 2014 Oct 2.

25.

Molecular composition and ultrastructure of the caveolar coat complex.

Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, Nichols BJ.

PLoS Biol. 2013;11(8):e1001640. doi: 10.1371/journal.pbio.1001640. Epub 2013 Aug 27.

26.

Synaptic inputs compete during rapid formation of the calyx of Held: a new model system for neural development.

Holcomb PS, Hoffpauir BK, Hoyson MC, Jackson DR, Deerinck TJ, Marrs GS, Dehoff M, Wu J, Ellisman MH, Spirou GA.

J Neurosci. 2013 Aug 7;33(32):12954-69. doi: 10.1523/JNEUROSCI.1087-13.2013.

27.

Catastrophic nuclear envelope collapse in cancer cell micronuclei.

Hatch EM, Fischer AH, Deerinck TJ, Hetzer MW.

Cell. 2013 Jul 3;154(1):47-60. doi: 10.1016/j.cell.2013.06.007.

28.

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.

Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, Moscat J, Diaz-Meco M, Dawson D, Erkan M, Kleeff J, Karin M.

J Clin Invest. 2013 May;123(5):2231-43. doi: 10.1172/JCI64498. Epub 2013 Apr 8.

29.

Abundant SAR11 viruses in the ocean.

Zhao Y, Temperton B, Thrash JC, Schwalbach MS, Vergin KL, Landry ZC, Ellisman M, Deerinck T, Sullivan MB, Giovannoni SJ.

Nature. 2013 Feb 21;494(7437):357-60. doi: 10.1038/nature11921. Epub 2013 Feb 13.

PMID:
23407494
30.

Construction of a polarized neuron.

Holcomb PS, Deerinck TJ, Ellisman MH, Spirou GA.

J Physiol. 2013 Jul 1;591(13):3145-50. doi: 10.1113/jphysiol.2012.248542. Epub 2013 Jan 21. Review.

31.

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

Davalos D, Ryu JK, Merlini M, Baeten KM, Le Moan N, Petersen MA, Deerinck TJ, Smirnoff DS, Bedard C, Hakozaki H, Gonias Murray S, Ling JB, Lassmann H, Degen JL, Ellisman MH, Akassoglou K.

Nat Commun. 2012;3:1227. doi: 10.1038/ncomms2230.

32.

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy.

Martell JD, Deerinck TJ, Sancak Y, Poulos TL, Mootha VK, Sosinsky GE, Ellisman MH, Ting AY.

Nat Biotechnol. 2012 Nov;30(11):1143-8. doi: 10.1038/nbt.2375. Epub 2012 Oct 21.

33.

A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.

Ou HD, Kwiatkowski W, Deerinck TJ, Noske A, Blain KY, Land HS, Soria C, Powers CJ, May AP, Shu X, Tsien RY, Fitzpatrick JA, Long JA, Ellisman MH, Choe S, O'Shea CC.

Cell. 2012 Oct 12;151(2):304-19. doi: 10.1016/j.cell.2012.08.035.

34.

Picking faces out of a crowd: genetic labels for identification of proteins in correlated light and electron microscopy imaging.

Ellisman MH, Deerinck TJ, Shu X, Sosinsky GE.

Methods Cell Biol. 2012;111:139-55. doi: 10.1016/B978-0-12-416026-2.00008-X. Review.

35.

Advancing the state of the art. Interview by Kristie Nybo.

Deerinck T.

Biotechniques. 2011 Nov;51(5):311. doi: 10.2144/000113758. No abstract available.

36.

A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms.

Shu X, Lev-Ram V, Deerinck TJ, Qi Y, Ramko EB, Davidson MW, Jin Y, Ellisman MH, Tsien RY.

PLoS Biol. 2011 Apr;9(4):e1001041. doi: 10.1371/journal.pbio.1001041. Epub 2011 Apr 5.

37.

Spiers Memorial Lecture. Breeding and building molecular spies.

Shu X, Lev-Ram V, Olson ES, Aguilera TA, Jiang T, Whitney M, Crisp JL, Steinbach P, Deerinck T, Ellisman MH, Ellies LG, Nguyen QT, Tsien RY.

Faraday Discuss. 2011;149:9; discussion 63-77.

PMID:
21413170
38.

Investigating synapse formation and function using human pluripotent stem cell-derived neurons.

Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3005-10. doi: 10.1073/pnas.1007753108. Epub 2011 Jan 28.

39.

Correlated live cell light and electron microscopy using tetracysteine tags and biarsenicals.

Gaietta GM, Deerinck TJ, Ellisman MH.

Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.top94. doi: 10.1101/pdb.top94.

PMID:
21205860
40.

Fluorescence photoconversion of biarsenical-labeled cells for correlated electron microscopy (EM).

Gaietta GM, Deerinck TJ, Ellisman MH.

Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5548. doi: 10.1101/pdb.prot5548.

PMID:
21205848
41.

Labeling tetracysteine-tagged proteins with biarsenical dyes for live cell imaging.

Gaietta GM, Deerinck TJ, Ellisman MH.

Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5547. doi: 10.1101/pdb.prot5547.

PMID:
21205847
42.

Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety.

Xia K, Xiong H, Shin Y, Wang D, Deerinck T, Takahashi H, Ellisman MH, Lipton SA, Tong G, Descalzi G, Zhang D, Zhuo M, Zhang Z.

Mol Brain. 2010 Aug 2;3:23. doi: 10.1186/1756-6606-3-23.

43.

Direct restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particles.

Fitzpatrick K, Skasko M, Deerinck TJ, Crum J, Ellisman MH, Guatelli J.

PLoS Pathog. 2010 Mar 5;6(3):e1000701. doi: 10.1371/journal.ppat.1000701.

44.

Structure-function studies of blood and air capillaries in chicken lung using 3D electron microscopy.

West JB, Fu Z, Deerinck TJ, Mackey MR, Obayashi JT, Ellisman MH.

Respir Physiol Neurobiol. 2010 Feb 28;170(2):202-9. doi: 10.1016/j.resp.2009.12.010. Epub 2009 Dec 28.

45.

The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum.

Lichtenstein A, Gaietta GM, Deerinck TJ, Crum J, Sosinsky GE, Beyer EC, Berthoud VM.

Exp Eye Res. 2009 Mar;88(3):600-9. doi: 10.1016/j.exer.2008.11.024. Epub 2008 Dec 6.

46.

Quantum dots for tracking dendritic cells and priming an immune response in vitro and in vivo.

Sen D, Deerinck TJ, Ellisman MH, Parker I, Cahalan MD.

PLoS One. 2008 Sep 29;3(9):e3290. doi: 10.1371/journal.pone.0003290.

47.

The application of fluorescent quantum dots to confocal, multiphoton, and electron microscopic imaging.

Deerinck TJ.

Toxicol Pathol. 2008 Jan;36(1):112-6. doi: 10.1177/0192623307310950.

48.

Regulation of spine morphology and spine density by NMDA receptor signaling in vivo.

Ultanir SK, Kim JE, Hall BJ, Deerinck T, Ellisman M, Ghosh A.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19553-8. Epub 2007 Nov 28.

49.

Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists.

Khan IM, Wart CV, Singletary EA, Stanislaus S, Deerinck T, Yaksh TL, Printz MP.

Neuropharmacology. 2008 Feb;54(2):269-79. Epub 2007 Oct 17.

50.

Visualizing flock house virus infection in Drosophila cells with correlated fluorescence and electron microscopy.

Lanman J, Crum J, Deerinck TJ, Gaietta GM, Schneemann A, Sosinsky GE, Ellisman MH, Johnson JE.

J Struct Biol. 2008 Mar;161(3):439-46. Epub 2007 Sep 19.

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