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Items: 31


African-American and Caucasian participation in postmortem human brain donation for neuropsychiatric research.

Deep-Soboslay A, Mighdoll MI, Jaffe AE, Thomas SB, Herman MM, Sirovatka J, King JP, Fowler DR, Zulauf D, DiAngelo C, Hyde TM, Kleinman JE.

PLoS One. 2019 Oct 23;14(10):e0222565. doi: 10.1371/journal.pone.0222565. eCollection 2019.


Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.

Collado-Torres L, Burke EE, Peterson A, Shin J, Straub RE, Rajpurohit A, Semick SA, Ulrich WS; BrainSeq Consortium, Price AJ, Valencia C, Tao R, Deep-Soboslay A, Hyde TM, Kleinman JE, Weinberger DR, Jaffe AE.

Neuron. 2019 Jul 17;103(2):203-216.e8. doi: 10.1016/j.neuron.2019.05.013. Epub 2019 Jun 4.


Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease.

Semick SA, Bharadwaj RA, Collado-Torres L, Tao R, Shin JH, Deep-Soboslay A, Weiss JR, Weinberger DR, Hyde TM, Kleinman JE, Jaffe AE, Mattay VS.

Acta Neuropathol. 2019 Apr;137(4):557-569. doi: 10.1007/s00401-019-01966-5. Epub 2019 Feb 2.


Association of a Noncoding RNA Postmortem With Suicide by Violent Means and In Vivo With Aggressive Phenotypes.

Punzi G, Ursini G, Viscanti G, Radulescu E, Shin JH, Quarto T, Catanesi R, Blasi G, Jaffe AE, Deep-Soboslay A, Hyde TM, Kleinman JE, Bertolino A, Weinberger DR.

Biol Psychiatry. 2019 Mar 1;85(5):417-424. doi: 10.1016/j.biopsych.2018.11.002. Epub 2018 Nov 16.


Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome.

Semick SA, Collado-Torres L, Markunas CA, Shin JH, Deep-Soboslay A, Tao R, Huestis MA, Bierut LJ, Maher BS, Johnson EO, Hyde TM, Weinberger DR, Hancock DB, Kleinman JE, Jaffe AE.

Mol Psychiatry. 2018 Aug 21. doi: 10.1038/s41380-018-0223-1. [Epub ahead of print]


Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.

Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; BrainSeq Consortium, Cross AJ, Brandon NJ, Leek JT, Hyde TM, Kleinman JE, Weinberger DR.

Nat Neurosci. 2018 Aug;21(8):1117-1125. doi: 10.1038/s41593-018-0197-y. Epub 2018 Jul 26.


Implementation and clinical characteristics of a posttraumatic stress disorder brain collection.

Mighdoll MI, Deep-Soboslay A, Bharadwaj RA, Cotoia JA, Benedek DM, Hyde TM, Kleinman JE.

J Neurosci Res. 2018 Jan;96(1):16-20. doi: 10.1002/jnr.24093. Epub 2017 Jun 13.


Altered expression of histamine signaling genes in autism spectrum disorder.

Wright C, Shin JH, Rajpurohit A, Deep-Soboslay A, Collado-Torres L, Brandon NJ, Hyde TM, Kleinman JE, Jaffe AE, Cross AJ, Weinberger DR.

Transl Psychiatry. 2017 May 9;7(5):e1126. doi: 10.1038/tp.2017.87.


Genetic risk mechanisms of posttraumatic stress disorder in the human brain.

Bharadwaj RA, Jaffe AE, Chen Q, Deep-Soboslay A, Goldman AL, Mighdoll MI, Cotoia JA, Brandtjen AC, Shin J, Hyde TM, Mattay VS, Weinberger DR, Kleinman JE.

J Neurosci Res. 2018 Jan;96(1):21-30. doi: 10.1002/jnr.23957. Epub 2016 Oct 24.


Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex.

Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR, Kleinman JE.

Nat Neurosci. 2016 Jan;19(1):40-7. doi: 10.1038/nn.4181. Epub 2015 Nov 30.


Sex differences in glutamate receptor gene expression in major depression and suicide.

Gray AL, Hyde TM, Deep-Soboslay A, Kleinman JE, Sodhi MS.

Mol Psychiatry. 2015 Sep;20(9):1139. doi: 10.1038/mp.2015.114. Epub 2015 Jul 28. No abstract available.


CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.

Kunii Y, Zhang W, Xu Q, Hyde TM, McFadden W, Shin JH, Deep-Soboslay A, Ye T, Li C, Kleinman JE, Wang KH, Lipska BK.

Am J Psychiatry. 2015 Nov 1;172(11):1122-30. doi: 10.1176/appi.ajp.2015.14080978. Epub 2015 Jul 24.


Sex differences in glutamate receptor gene expression in major depression and suicide.

Gray AL, Hyde TM, Deep-Soboslay A, Kleinman JE, Sodhi MS.

Mol Psychiatry. 2015 Sep;20(9):1057-68. doi: 10.1038/mp.2015.91. Epub 2015 Jul 14. Erratum in: Mol Psychiatry. 2015 Sep;20(9):1139.


Genetic neuropathology of obsessive psychiatric syndromes.

Jaffe AE, Deep-Soboslay A, Tao R, Hauptman DT, Kaye WH, Arango V, Weinberger DR, Hyde TM, Kleinman JE.

Transl Psychiatry. 2014 Sep 2;4:e432. doi: 10.1038/tp.2014.68.


Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain.

Kaalund SS, Newburn EN, Ye T, Tao R, Li C, Deep-Soboslay A, Herman MM, Hyde TM, Weinberger DR, Lipska BK, Kleinman JE.

Mol Psychiatry. 2014 Dec;19(12):1258-66. doi: 10.1038/mp.2013.165. Epub 2013 Dec 10.


Use of postmortem human dura mater and scalp for deriving human fibroblast cultures.

Bliss LA, Sams MR, Deep-Soboslay A, Ren-Patterson R, Jaffe AE, Chenoweth JG, Jaishankar A, Kleinman JE, Hyde TM.

PLoS One. 2012;7(9):e45282. doi: 10.1371/journal.pone.0045282. Epub 2012 Sep 27.


Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia.

Jenko KJ, Hirvonen J, Henter ID, Anderson KB, Zoghbi SS, Hyde TM, Deep-Soboslay A, Innis RB, Kleinman JE.

Schizophr Res. 2012 Nov;141(2-3):185-8. doi: 10.1016/j.schres.2012.07.021. Epub 2012 Aug 19.


Psychiatric brain banking: three perspectives on current trends and future directions.

Deep-Soboslay A, Benes FM, Haroutunian V, Ellis JK, Kleinman JE, Hyde TM.

Biol Psychiatry. 2011 Jan 15;69(2):104-12. doi: 10.1016/j.biopsych.2010.05.025. Epub 2010 Jul 31. Review.


Handedness, heritability, neurocognition and brain asymmetry in schizophrenia.

Deep-Soboslay A, Hyde TM, Callicott JP, Lener MS, Verchinski BA, Apud JA, Weinberger DR, Elvevåg B.

Brain. 2010 Oct;133(10):3113-22. doi: 10.1093/brain/awq160. Epub 2010 Jul 17.


Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia.

Wong J, Hyde TM, Cassano HL, Deep-Soboslay A, Kleinman JE, Weickert CS.

Neuroscience. 2010 Sep 1;169(3):1071-84. doi: 10.1016/j.neuroscience.2010.05.037. Epub 2010 May 27.


Evaluation of tissue collection for postmortem studies of bipolar disorder.

Deep-Soboslay A, Iglesias B, Hyde TM, Bigelow LB, Imamovic V, Herman MM, Kleinman JE.

Bipolar Disord. 2008 Nov;10(7):822-8. doi: 10.1111/j.1399-5618.2008.00607.x.


Enuresis as a premorbid developmental marker of schizophrenia.

Hyde TM, Deep-Soboslay A, Iglesias B, Callicott JH, Gold JM, Meyer-Lindenberg A, Honea RA, Bigelow LB, Egan MF, Emsellem EM, Weinberger DR.

Brain. 2008 Sep;131(Pt 9):2489-98. doi: 10.1093/brain/awn167. Epub 2008 Jul 31.


Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex.

Colantuoni C, Hyde TM, Mitkus S, Joseph A, Sartorius L, Aguirre C, Creswell J, Johnson E, Deep-Soboslay A, Herman MM, Lipska BK, Weinberger DR, Kleinman JE.

Brain Struct Funct. 2008 Sep;213(1-2):255-71. doi: 10.1007/s00429-008-0181-5. Epub 2008 May 10. Erratum in: Brain Struct Funct. 2008 Sep;213(1-2):273.


Postmortem diagnosis and toxicological validation of illicit substance use.

Lehrmann E, Afanador ZR, Deep-Soboslay A, Gallegos G, Darwin WD, Lowe RH, Barnes AJ, Huestis MA, Cadet JL, Herman MM, Hyde TM, Kleinman JE, Freed WJ.

Addict Biol. 2008 Mar;13(1):105-17. doi: 10.1111/j.1369-1600.2007.00085.x. Epub 2008 Jan 14.


Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds.

Halim ND, Lipska BK, Hyde TM, Deep-Soboslay A, Saylor EM, Herman MM, Thakar J, Verma A, Kleinman JE.

J Neurosci Methods. 2008 Mar 30;169(1):208-13. doi: 10.1016/j.jneumeth.2007.11.017. Epub 2007 Nov 29.


Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.

Lehrmann E, Colantuoni C, Deep-Soboslay A, Becker KG, Lowe R, Huestis MA, Hyde TM, Kleinman JE, Freed WJ.

PLoS One. 2006 Dec 27;1:e114.


Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.

Lipska BK, Deep-Soboslay A, Weickert CS, Hyde TM, Martin CE, Herman MM, Kleinman JE.

Biol Psychiatry. 2006 Sep 15;60(6):650-8.


The development of a posttraumatic stress disorder brain collection.

Deep-Soboslay A, Martin CE, Kleinman JE.

Psychiatry. 2004 Winter;67(4):416-8. No abstract available.


Reliability of psychiatric diagnosis in postmortem research.

Deep-Soboslay A, Akil M, Martin CE, Bigelow LB, Herman MM, Hyde TM, Kleinman JE.

Biol Psychiatry. 2005 Jan 1;57(1):96-101.


Candidate gene analysis of the Price Foundation anorexia nervosa affected relative pair dataset.

Bergen AW, Yeager M, Welch R, Ganjei JK, Deep-Soboslay A, Haque K, van den Bree MB, Goldman D, Berrettini WH, Kaye WH; Price Foundation Collaborative Group (

Curr Drug Targets CNS Neurol Disord. 2003 Feb;2(1):41-51. Review.


Weight gain with anorexia nervosa.

Deep-Soboslay A, Sebastiani LM, Kaye WH.

Am J Psychiatry. 2000 Sep;157(9):1526. No abstract available.


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