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Items: 1 to 50 of 150

1.

Structural Insights into AQP2 Targeting to Multivesicular Bodies.

Roche JV, Nesverova V, Olsson C, Deen PM, Törnroth-Horsefield S.

Int J Mol Sci. 2019 Oct 28;20(21). pii: E5351. doi: 10.3390/ijms20215351.

2.

Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice.

de Groot T, Ebert LK, Christensen BM, Andralojc K, Cheval L, Doucet A, Mao C, Baumgarten R, Low BE, Sandhoff R, Wiles MV, Deen PMT, Korstanje R.

J Am Soc Nephrol. 2019 Sep 26. pii: ASN.2018050549. doi: 10.1681/ASN.2018050549. [Epub ahead of print]

PMID:
31558682
3.

Renal concentrating ability and glomerular filtration rate in lithium-treated patients.

Doornebal J, Diepenbroek A, van de Luijtgaarden MWM, Hartong EGTM, Grootens KP, Kupka RW, Klumpers UMH, Deen PMT, Gaillard CA, Wetzels JFM.

Neth J Med. 2019 May;77(4):139-149.

4.

Single nucleotide polymorphism rs13079080 is associated with differential regulation of the succinate receptor 1 (SUCNR1) gene by miRNA-4470.

Louer EMM, Lorés-Motta L, Ion AM, Den Hollander AI, Deen PMT.

RNA Biol. 2019 Nov;16(11):1547-1554. doi: 10.1080/15476286.2019.1643100. Epub 2019 Jul 24.

5.

Impact of acute versus prolonged exercise and dehydration on kidney function and injury.

Bongers CCWG, Alsady M, Nijenhuis T, Tulp ADM, Eijsvogels TMH, Deen PMT, Hopman MTE.

Physiol Rep. 2018 Jun;6(11):e13734. doi: 10.14814/phy2.13734.

6.

MicroRNA-132 controls water homeostasis through regulating MECP2-mediated vasopressin synthesis.

Bijkerk R, Trimpert C, van Solingen C, de Bruin RG, Florijn BW, Kooijman S, van den Berg R, van der Veer EP, Bredewold EOW, Rensen PCN, Rabelink TJ, Humphreys BD, Deen PMT, van Zonneveld AJ.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1129-F1138. doi: 10.1152/ajprenal.00087.2018. Epub 2018 May 30.

7.

Impact of acute versus repetitive moderate intensity endurance exercise on kidney injury markers.

Bongers CCWG, Alsady M, Nijenhuis T, Hartman YAW, Eijsvogels TMH, Deen PMT, Hopman MTE.

Physiol Rep. 2017 Dec;5(24). pii: e13544. doi: 10.14814/phy2.13544.

8.

Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice.

de Groot T, Damen L, Kosse L, Alsady M, Doty R, Baumgarten R, Sheehan S, van der Vlag J, Korstanje R, Deen PMT.

PLoS One. 2017 Dec 15;12(12):e0189485. doi: 10.1371/journal.pone.0189485. eCollection 2017.

9.

AQP2 Abundance is Regulated by the E3-Ligase CHIP Via HSP70.

Centrone M, Ranieri M, Di Mise A, Berlingerio SP, Russo A, Deen PMT, Staub O, Valenti G, Tamma G.

Cell Physiol Biochem. 2017;44(2):515-531. doi: 10.1159/000485088. Epub 2017 Nov 17.

10.

Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells.

Alsady M, de Groot T, Kortenoeven MLA, Carmone C, Neijman K, Bekkenkamp-Grovenstein M, Engelke U, Wevers R, Baumgarten R, Korstanje R, Deen PMT.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F230-F239. doi: 10.1152/ajprenal.00297.2017. Epub 2017 Oct 25.

11.

NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation.

Trimpert C, Wesche D, de Groot T, Pimentel Rodriguez MM, Wong V, van den Berg DTM, Cheval L, Ariza CA, Doucet A, Stagljar I, Deen PMT.

PLoS One. 2017 Sep 20;12(9):e0183774. doi: 10.1371/journal.pone.0183774. eCollection 2017.

12.

Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH.

Lee JW, Alsady M, Chou CL, de Groot T, Deen PMT, Knepper MA, Ecelbarger CM.

Kidney Int. 2018 Jan;93(1):128-146. doi: 10.1016/j.kint.2017.06.008. Epub 2017 Aug 23.

13.

Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5.

Roche JV, Survery S, Kreida S, Nesverova V, Ampah-Korsah H, Gourdon M, Deen PMT, Törnroth-Horsefield S.

J Biol Chem. 2017 Sep 1;292(35):14636-14648. doi: 10.1074/jbc.M117.788364. Epub 2017 Jul 14.

14.

Lithium-induced NDI: acetazolamide reduces polyuria but does not improve urine concentrating ability.

de Groot T, Doornebal J, Christensen BM, Cockx S, Sinke AP, Baumgarten R, Bedford JJ, Walker RJ, Wetzels JFM, Deen PMT.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F669-F676. doi: 10.1152/ajprenal.00147.2017. Epub 2017 Jun 14.

15.

SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.

van Diepen JA, Robben JH, Hooiveld GJ, Carmone C, Alsady M, Boutens L, Bekkenkamp-Grovenstein M, Hijmans A, Engelke UFH, Wevers RA, Netea MG, Tack CJ, Stienstra R, Deen PMT.

Diabetologia. 2017 Jul;60(7):1304-1313. doi: 10.1007/s00125-017-4261-z. Epub 2017 Apr 5.

16.

Lithium in the Kidney: Friend and Foe?

Alsady M, Baumgarten R, Deen PM, de Groot T.

J Am Soc Nephrol. 2016 Jun;27(6):1587-95. doi: 10.1681/ASN.2015080907. Epub 2015 Nov 17. Review.

17.

Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus.

de Groot T, Sinke AP, Kortenoeven ML, Alsady M, Baumgarten R, Devuyst O, Loffing J, Wetzels JF, Deen PM.

J Am Soc Nephrol. 2016 Jul;27(7):2082-91. doi: 10.1681/ASN.2015070796. Epub 2015 Nov 16.

18.

Thiazide-induced hyponatraemia is associated with increased water intake and impaired urea-mediated water excretion at low plasma antidiuretic hormone and urine aquaporin-2.

Frenkel NJ, Vogt L, De Rooij SE, Trimpert C, Levi MM, Deen PM, van den Born BJ.

J Hypertens. 2015 Mar;33(3):627-33. doi: 10.1097/HJH.0000000000000423.

PMID:
25426567
19.

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG.

Science. 2014 Sep 26;345(6204):1250684. doi: 10.1126/science.1250684. Erratum in: Science. 2014 Nov 7;346(6210):aaa1503. van der Meer, Brian M J W [corrected to van der Veer, Brian M J W].

20.

Collecting duct principal cell transport processes and their regulation.

Pearce D, Soundararajan R, Trimpert C, Kashlan OB, Deen PM, Kohan DE.

Clin J Am Soc Nephrol. 2015 Jan 7;10(1):135-46. doi: 10.2215/CJN.05760513. Epub 2014 May 29. Review.

21.

X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking.

Frick A, Eriksson UK, de Mattia F, Oberg F, Hedfalk K, Neutze R, de Grip WJ, Deen PM, Törnroth-Horsefield S.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6305-10. doi: 10.1073/pnas.1321406111. Epub 2014 Apr 14.

22.

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency.

Tamma G, Lasorsa D, Trimpert C, Ranieri M, Di Mise A, Mola MG, Mastrofrancesco L, Devuyst O, Svelto M, Deen PM, Valenti G.

J Am Soc Nephrol. 2014 Oct;25(10):2241-53. doi: 10.1681/ASN.2013111234. Epub 2014 Apr 3.

23.

Lithium causes G2 arrest of renal principal cells.

de Groot T, Alsady M, Jaklofsky M, Otte-Höller I, Baumgarten R, Giles RH, Deen PM.

J Am Soc Nephrol. 2014 Mar;25(3):501-10. doi: 10.1681/ASN.2013090988. Epub 2014 Jan 9.

24.

Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter.

Sinke AP, Kortenoeven ML, de Groot T, Baumgarten R, Devuyst O, Wetzels JF, Loffing J, Deen PM.

Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F525-33. doi: 10.1152/ajprenal.00617.2013. Epub 2013 Dec 18.

25.

Demeclocycline attenuates hyponatremia by reducing aquaporin-2 expression in the renal inner medulla.

Kortenoeven ML, Sinke AP, Hadrup N, Trimpert C, Wetzels JF, Fenton RA, Deen PM.

Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1705-18. doi: 10.1152/ajprenal.00723.2012. Epub 2013 Oct 23.

26.

Intellectual disability and bleeding diathesis due to deficient CMP--sialic acid transport.

Mohamed M, Ashikov A, Guillard M, Robben JH, Schmidt S, van den Heuvel B, de Brouwer AP, Gerardy-Schahn R, Deen PM, Wevers RA, Lefeber DJ, Morava E.

Neurology. 2013 Aug 13;81(7):681-7. doi: 10.1212/WNL.0b013e3182a08f53. Epub 2013 Jul 19.

PMID:
23873973
27.

Small-molecule screening identifies modulators of aquaporin-2 trafficking.

Bogum J, Faust D, Zühlke K, Eichhorst J, Moutty MC, Furkert J, Eldahshan A, Neuenschwander M, von Kries JP, Wiesner B, Trimpert C, Deen PM, Valenti G, Rosenthal W, Klussmann E.

J Am Soc Nephrol. 2013 Apr;24(5):744-58. doi: 10.1681/ASN.2012030295. Epub 2013 Apr 4.

28.

Aquaporin-2 levels in vitro and in vivo are regulated by VACM-1, a cul 5 gene.

Le IP, Schultz S, Andresen BT, Dewey GL, Zhao P, Listenberger L, Deen PM, Buchwalter A, Barney CC, Burnatowska-Hledin MA.

Cell Physiol Biochem. 2012;30(5):1148-58. doi: 10.1159/000343305. Epub 2012 Oct 5.

29.

CO2 permeability of cell membranes is regulated by membrane cholesterol and protein gas channels.

Itel F, Al-Samir S, Öberg F, Chami M, Kumar M, Supuran CT, Deen PM, Meier W, Hedfalk K, Gros G, Endeward V.

FASEB J. 2012 Dec;26(12):5182-91. doi: 10.1096/fj.12-209916. Epub 2012 Sep 10.

PMID:
22964306
30.

Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.

Trimpert C, van den Berg DT, Fenton RA, Klussmann E, Deen PM.

Nephrol Dial Transplant. 2012 Dec;27(12):4389-97. doi: 10.1093/ndt/gfs292. Epub 2012 Jul 9.

PMID:
22778181
31.

The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions.

Ariza AC, Deen PM, Robben JH.

Front Endocrinol (Lausanne). 2012 Feb 16;3:22. doi: 10.3389/fendo.2012.00022. eCollection 2012.

32.

Congenital nephrogenic diabetes insipidus: the current state of affairs.

Wesche D, Deen PM, Knoers NV.

Pediatr Nephrol. 2012 Dec;27(12):2183-204. doi: 10.1007/s00467-012-2118-8. Epub 2012 Mar 17. Review.

PMID:
22427315
33.

In mpkCCD cells, long-term regulation of aquaporin-2 by vasopressin occurs independent of protein kinase A and CREB but may involve Epac.

Kortenoeven ML, Trimpert C, van den Brand M, Li Y, Wetzels JF, Deen PM.

Am J Physiol Renal Physiol. 2012 Jun 1;302(11):F1395-401. doi: 10.1152/ajprenal.00376.2011. Epub 2012 Mar 14.

34.

Lithium reduces aquaporin-2 transcription independent of prostaglandins.

Kortenoeven ML, Schweer H, Cox R, Wetzels JF, Deen PM.

Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C131-40. doi: 10.1152/ajpcell.00197.2011. Epub 2011 Aug 31.

35.

Succinate receptors in the kidney.

Deen PM, Robben JH.

J Am Soc Nephrol. 2011 Aug;22(8):1416-22. doi: 10.1681/ASN.2010050481. Review.

36.

The physiological implication of novel proteins in systemic osmoregulation.

Sinke AP, Deen PM.

FASEB J. 2011 Oct;25(10):3279-89. doi: 10.1096/fj.11-188433. Epub 2011 Jul 7. Review.

PMID:
21737616
37.

Novel mutation in the AVPR2 gene in a Danish male with nephrogenic diabetes insipidus caused by ER retention and subsequent lysosomal degradation of the mutant receptor.

Nejsum LN, Christensen TM, Robben JH, Milligan G, Deen PM, Bichet DG, Levin K.

NDT Plus. 2011 Jun;4(3):158-163. Epub 2011 Mar 2.

38.

Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study.

Rennings AJ, Russel FG, Li Y, Deen PM, Masereeuw R, Tack CJ, Smits P.

Clin Pharmacol Ther. 2011 Apr;89(4):587-94. doi: 10.1038/clpt.2010.360. Epub 2011 Mar 2.

PMID:
21368750
39.

Hypotonicity-induced reduction of aquaporin-2 transcription in mpkCCD cells is independent of the tonicity responsive element, vasopressin, and cAMP.

Kortenoeven ML, van den Brand M, Wetzels JF, Deen PM.

J Biol Chem. 2011 Apr 15;286(15):13002-10. doi: 10.1074/jbc.M110.207878. Epub 2011 Feb 15.

40.

Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of action.

Boone M, Kortenoeven ML, Robben JH, Tamma G, Deen PM.

Am J Physiol Renal Physiol. 2011 Mar;300(3):F761-71. doi: 10.1152/ajprenal.00247.2010. Epub 2011 Jan 5.

41.

Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation.

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R.

Physiol Genomics. 2011 Mar 16;43(5):265-70. doi: 10.1152/physiolgenomics.00188.2010. Epub 2010 Dec 21.

42.

Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.

Tamma G, Robben JH, Trimpert C, Boone M, Deen PM.

Am J Physiol Cell Physiol. 2011 Mar;300(3):C636-46. doi: 10.1152/ajpcell.00433.2009. Epub 2010 Dec 9.

43.

alphaENaC-mediated lithium absorption promotes nephrogenic diabetes insipidus.

Christensen BM, Zuber AM, Loffing J, Stehle JC, Deen PM, Rossier BC, Hummler E.

J Am Soc Nephrol. 2011 Feb;22(2):253-61. doi: 10.1681/ASN.2010070734. Epub 2010 Nov 4.

44.

Autosomal recessive mental retardation, deafness, ankylosis, and mild hypophosphatemia associated with a novel ANKH mutation in a consanguineous family.

Morava E, Kühnisch J, Drijvers JM, Robben JH, Cremers C, van Setten P, Branten A, Stumpp S, de Jong A, Voesenek K, Vermeer S, Heister A, Claahsen-van der Grinten HL, O'Neill CW, Willemsen MA, Lefeber D, Deen PM, Kornak U, Kremer H, Wevers RA.

J Clin Endocrinol Metab. 2011 Jan;96(1):E189-98. doi: 10.1210/jc.2010-1539. Epub 2010 Oct 13.

45.

A systems biology approach: modelling of Aquaporin-2 trafficking.

Fröhlich M, Deen PM, Klipp E.

Genome Inform. 2010;24:42-55.

PMID:
22081588
46.

Functional variation in the arginine vasopressin 2 receptor as a modifier of human plasma von Willebrand factor levels.

Nossent AY, Robben JH, Deen PM, Vos HL, Rosendaal FR, Doggen CJ, Hansen JL, Sheikh SP, Bertina RM, Eikenboom JC.

J Thromb Haemost. 2010 Jul;8(7):1547-54. doi: 10.1111/j.1538-7836.2010.03884.x. Epub 2010 Apr 16.

47.

RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter.

Ko B, Kamsteeg EJ, Cooke LL, Moddes LN, Deen PM, Hoover RS.

Am J Physiol Renal Physiol. 2010 Aug;299(2):F300-9. doi: 10.1152/ajprenal.00441.2009. Epub 2010 Apr 14.

48.

The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.

Boone M, Mobasheri A, Fenton RA, van Balkom BW, Wismans R, van der Zee CE, Deen PM.

J Mol Histol. 2010 Feb;41(1):61-74. doi: 10.1007/s10735-010-9263-9. Epub 2010 Apr 1.

PMID:
20358264
49.

Potential of nonpeptide (ant)agonists to rescue vasopressin V2 receptor mutants for the treatment of X-linked nephrogenic diabetes insipidus.

Los EL, Deen PM, Robben JH.

J Neuroendocrinol. 2010 May;22(5):393-9. doi: 10.1111/j.1365-2826.2010.01983.x. Epub 2010 Feb 12. Review.

PMID:
20163515
50.

Blockade of dopamine, but not noradrenaline, transporters produces hyperthermia in rats that lack serotonin transporters.

Olivier JD, Cools AR, Deen PM, Olivier B, Ellenbroek BA.

Eur J Pharmacol. 2010 Mar 10;629(1-3):7-11. doi: 10.1016/j.ejphar.2009.11.049. Epub 2009 Dec 21.

PMID:
20004658

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