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Items: 31

1.

Antidepressants induce profibrotic responses via the lysophosphatidic acid receptor LPA1.

Olianas MC, Dedoni S, Onali P.

Eur J Pharmacol. 2020 Apr 15;873:172963. doi: 10.1016/j.ejphar.2020.172963. Epub 2020 Jan 30.

PMID:
32007501
2.

Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors.

Dedoni S, Marras L, Olianas MC, Ingianni A, Onali P.

J Pharmacol Exp Ther. 2019 Sep;370(3):490-503. doi: 10.1124/jpet.119.258129. Epub 2019 Jul 15.

PMID:
31308194
3.

Inhibition of TNF-α-induced neuronal apoptosis by antidepressants acting through the lysophosphatidic acid receptor LPA1.

Olianas MC, Dedoni S, Onali P.

Apoptosis. 2019 Jun;24(5-6):478-498. doi: 10.1007/s10495-019-01530-2.

PMID:
30840161
4.

The orphan G-protein-coupled receptor 75 signaling is activated by the chemokine CCL5.

Dedoni S, Campbell LA, Harvey BK, Avdoshina V, Mocchetti I.

J Neurochem. 2018 Sep;146(5):526-539. doi: 10.1111/jnc.14463. Epub 2018 Aug 2.

6.

LPA1 is a key mediator of intracellular signalling and neuroprotection triggered by tetracyclic antidepressants in hippocampal neurons.

Olianas MC, Dedoni S, Onali P.

J Neurochem. 2017 Oct;143(2):183-197. doi: 10.1111/jnc.14150. Epub 2017 Sep 11.

7.

The GABAB positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABAB receptors.

Olianas MC, Dedoni S, Onali P.

Eur J Pharmacol. 2017 Jan 5;794:135-146. doi: 10.1016/j.ejphar.2016.11.030. Epub 2016 Nov 19.

PMID:
27876620
8.

LPA1 Mediates Antidepressant-Induced ERK1/2 Signaling and Protection from Oxidative Stress in Glial Cells.

Olianas MC, Dedoni S, Onali P.

J Pharmacol Exp Ther. 2016 Nov;359(2):340-353. Epub 2016 Sep 7.

PMID:
27605627
9.

Protection from interferon-β-induced neuronal apoptosis through stimulation of muscarinic acetylcholine receptors coupled to ERK1/2 activation.

Olianas MC, Dedoni S, Onali P.

Br J Pharmacol. 2016 Oct;173(19):2910-28. doi: 10.1111/bph.13570. Epub 2016 Aug 26.

10.

The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons.

Avdoshina V, Fields JA, Castellano P, Dedoni S, Palchik G, Trejo M, Adame A, Rockenstein E, Eugenin E, Masliah E, Mocchetti I.

Neurotox Res. 2016 May;29(4):583-593. doi: 10.1007/s12640-016-9608-6. Epub 2016 Mar 2.

11.

Interferon-β Inhibits Neurotrophin 3 Signalling and Pro-Survival Activity by Upregulating the Expression of Truncated TrkC-T1 Receptor.

Dedoni S, Olianas MC, Ingianni A, Onali P.

Mol Neurobiol. 2017 Apr;54(3):1825-1843. doi: 10.1007/s12035-016-9789-2. Epub 2016 Feb 18.

PMID:
26887385
12.

Identification of a binding site of the human immunodeficiency virus envelope protein gp120 to neuronal-specific tubulin.

Avdoshina V, Taraballi F, Dedoni S, Corbo C, Paige M, Saygideğer Kont Y, Üren A, Tasciotti E, Mocchetti I.

J Neurochem. 2016 Apr;137(2):287-98. doi: 10.1111/jnc.13557. Epub 2016 Mar 15.

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Interferon-β counter-regulates its own pro-apoptotic action by activating p38 MAPK signalling in human SH-SY5Y neuroblastoma cells.

Dedoni S, Olianas MC, Onali P.

Apoptosis. 2014 Oct;19(10):1509-26. doi: 10.1007/s10495-014-1024-x.

PMID:
25086905
16.

Preclinical and clinical phase I studies of a new recombinant Filgrastim (BK0023) in comparison with Neupogen®.

Crobu D, Spinetti G, Schrepfer R, Tonon G, Jotti GS, Onali P, Dedoni S, Orsini G, Di Stefano A.

BMC Pharmacol Toxicol. 2014 Feb 21;15:7. doi: 10.1186/2050-6511-15-7.

17.

Type I interferons up-regulate the expression and signalling of p75 NTR/TrkA receptor complex in differentiated human SH-SY5Y neuroblastoma cells.

Dedoni S, Olianas MC, Ingianni A, Onali P.

Neuropharmacology. 2014 Apr;79:321-34. doi: 10.1016/j.neuropharm.2013.12.002. Epub 2013 Dec 11.

PMID:
24333329
18.

Potentiation of dopamine D1-like receptor signaling by concomitant activation of δ- and μ-opioid receptors in mouse medial prefrontal cortex.

Olianas MC, Dedoni S, Onali P.

Neurochem Int. 2012 Dec;61(8):1404-16. doi: 10.1016/j.neuint.2012.10.005. Epub 2012 Oct 13.

PMID:
23073238
19.

The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors.

Olianas MC, Dedoni S, Onali P.

Br J Pharmacol. 2012 Nov;167(6):1329-41. doi: 10.1111/j.1476-5381.2012.02078.x.

20.

Type I interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons.

Dedoni S, Olianas MC, Ingianni A, Onali P.

J Neurochem. 2012 Jul;122(1):58-71. doi: 10.1111/j.1471-4159.2012.07766.x. Epub 2012 May 21.

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22.

Enzymatic mono-pegylation of glucagon-like peptide 1 towards long lasting treatment of type 2 diabetes.

Selis F, Schrepfer R, Sanna R, Scaramuzza S, Tonon G, Dedoni S, Onali P, Orsini G, Genovese S.

Results Pharma Sci. 2012 Sep 18;2:58-65. doi: 10.1016/j.rinphs.2012.09.001. eCollection 2012.

23.

δ-Opioid receptors stimulate the metabolic sensor AMP-activated protein kinase through coincident signaling with G(q/11)-coupled receptors.

Olianas MC, Dedoni S, Olianas A, Onali P.

Mol Pharmacol. 2012 Feb;81(2):154-65. doi: 10.1124/mol.111.075267. Epub 2011 Oct 26.

PMID:
22031472
24.

Regulation of PI3K/Akt signaling by N-desmethylclozapine through activation of δ-opioid receptor.

Olianas MC, Dedoni S, Onali P.

Eur J Pharmacol. 2011 Jun 25;660(2-3):341-50. doi: 10.1016/j.ejphar.2011.04.012. Epub 2011 Apr 19.

PMID:
21515255
25.

Signaling pathways mediating phosphorylation and inactivation of glycogen synthase kinase-3β by the recombinant human δ-opioid receptor stably expressed in Chinese hamster ovary cells.

Olianas MC, Dedoni S, Onali P.

Neuropharmacology. 2011 Jun;60(7-8):1326-36. doi: 10.1016/j.neuropharm.2011.01.032. Epub 2011 Jan 27.

PMID:
21276805
26.

δ-Opioid receptors stimulate GLUT1-mediated glucose uptake through Src- and IGF-1 receptor-dependent activation of PI3-kinase signalling in CHO cells.

Olianas MC, Dedoni S, Onali P.

Br J Pharmacol. 2011 Jun;163(3):624-37. doi: 10.1111/j.1476-5381.2011.01234.x.

27.

Interferon-β induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK-STAT signaling and down-regulation of PI3K/Akt pathway.

Dedoni S, Olianas MC, Onali P.

J Neurochem. 2010 Dec;115(6):1421-33. doi: 10.1111/j.1471-4159.2010.07046.x. Epub 2010 Nov 11.

28.

Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes.

Onali P, Dedoni S, Olianas MC.

J Pharmacol Exp Ther. 2010 Jan;332(1):255-65. doi: 10.1124/jpet.109.159939. Epub 2009 Oct 14.

PMID:
19828880
29.

Agonist activity of N-desmethylclozapine at delta-opioid receptors of human frontal cortex.

Olianas MC, Dedoni S, Ambu R, Onali P.

Eur J Pharmacol. 2009 Apr 1;607(1-3):96-101. doi: 10.1016/j.ejphar.2009.02.025. Epub 2009 Feb 23.

PMID:
19239909
30.

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