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Items: 5


Role of GARP in the activation of latent TGF-β1.

Stockis J, Dedobbeleer O, Lucas S.

Mol Biosyst. 2017 Sep 26;13(10):1925-1935. doi: 10.1039/c7mb00251c. Review.


Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA.

Dedobbeleer O, Stockis J, van der Woning B, Coulie PG, Lucas S.

J Immunol. 2017 Jul 15;199(2):391-396. doi: 10.4049/jimmunol.1601882. Epub 2017 Jun 12.


Targeting immunosuppression by Tregs with monoclonal antibodies against GARP.

Liénart S, Stockis J, Dedobbeleer O, Lucas S.

Oncoimmunology. 2016 Feb 23;5(3):e1074379. eCollection 2016 Mar.


Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells.

Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie PG, Lucas S.

J Biol Chem. 2015 Aug 14;290(33):20105-16. doi: 10.1074/jbc.M115.655340. Epub 2015 Jun 30.


Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.

Cuende J, Liénart S, Dedobbeleer O, van der Woning B, De Boeck G, Stockis J, Huygens C, Colau D, Somja J, Delvenne P, Hannon M, Baron F, Dumoutier L, Renauld JC, De Haard H, Saunders M, Coulie PG, Lucas S.

Sci Transl Med. 2015 Apr 22;7(284):284ra56. doi: 10.1126/scitranslmed.aaa1983.

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