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Items: 23

1.

A novel fluorogenic substrate for the measurement of endothelial lipase activity.

Darrow AL, Olson MW, Xin H, Burke SL, Smith C, Schalk-Hihi C, Williams R, Bayoumy SS, Deckman IC, Todd MJ, Damiano BP, Connelly MA.

J Lipid Res. 2011 Feb;52(2):374-82. doi: 10.1194/jlr.D007971.

2.

Enhancing recombinant protein quality and yield by protein stability profiling.

Mezzasalma TM, Kranz JK, Chan W, Struble GT, Schalk-Hihi C, Deckman IC, Springer BA, Todd MJ.

J Biomol Screen. 2007 Apr;12(3):418-28.

PMID:
17438070
3.

Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.

Schalk-Hihi C, Ma HC, Struble GT, Bayoumy S, Williams R, Devine E, Petrounia IP, Mezzasalma T, Zeng L, Schubert C, Grasberger B, Springer BA, Deckman IC.

J Biol Chem. 2007 Feb 9;282(6):4085-93. Epub 2006 Nov 28.

4.

Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.

Schubert C, Schalk-Hihi C, Struble GT, Ma HC, Petrounia IP, Brandt B, Deckman IC, Patch RJ, Player MR, Spurlino JC, Springer BA.

J Biol Chem. 2007 Feb 9;282(6):4094-101. Epub 2006 Nov 28.

5.

Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.

Maroney AC, Marugan JJ, Mezzasalma TM, Barnakov AN, Garrabrant TA, Weaner LE, Jones WJ, Barnakova LA, Koblish HK, Todd MJ, Masucci JA, Deckman IC, Galemmo RA Jr, Johnson DL.

Biochemistry. 2006 May 2;45(17):5678-85.

PMID:
16634649
6.

Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.

Qiao L, Baumann CA, Crysler CS, Ninan NS, Abad MC, Spurlino JC, Desjarlais RL, Kervinen J, Neeper MP, Bayoumy SS, Williams R, Deckman IC, Dasgupta M, Reed RL, Huebert ND, Tomczuk BE, Moriarty KJ.

Bioorg Med Chem Lett. 2006 Jan 1;16(1):123-8. Epub 2005 Oct 19.

PMID:
16236500
7.

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF.

J Med Chem. 2005 Feb 24;48(4):909-12.

PMID:
15715460
8.

Design and synthesis of 4,5-disubstituted-thiophene-2-amidines as potent urokinase inhibitors.

Rudolph MJ, Illig CR, Subasinghe NL, Wilson KJ, Hoffman JB, Randle T, Green D, Molloy CJ, Soll RM, Lewandowski F, Zhang M, Bone R, Spurlino JC, Deckman IC, Manthey C, Sharp C, Maguire D, Grasberger BL, DesJarlais RL, Zhou Z.

Bioorg Med Chem Lett. 2002 Feb 11;12(3):491-5.

PMID:
11814826
9.

The 80's loop (residues 78 to 85) is important for the differential activity of retroviral proteases.

Stebbins J, Towler EM, Tennant MG, Deckman IC, Debouck C.

J Mol Biol. 1997 Apr 4;267(3):467-75.

PMID:
9126830
10.

A heterologous substrate assay for the HIV-1 protease engineered in Escherichia coli.

Stebbins J, Deckman IC, Richardson SB, Debouck C.

Anal Biochem. 1996 Nov 1;242(1):90-4.

PMID:
8923970
11.

Stimulation of the herpes simplex virus type I protease by antichaeotrophic salts.

Yamanaka G, DiIanni CL, O'Boyle DR 2nd, Stevens J, Weinheimer SP, Deckman IC, Matusick-Kumar L, Colonno RJ.

J Biol Chem. 1995 Dec 15;270(50):30168-72.

12.
13.

Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles.

Weinheimer SP, McCann PJ 3rd, O'Boyle DR 2nd, Stevens JT, Boyd BA, Drier DA, Yamanaka GA, DiIanni CL, Deckman IC, Cordingley MG.

J Virol. 1993 Oct;67(10):5813-22.

14.

Inhibitor binding to the Phe53Trp mutant of HIV-1 protease promotes conformational changes detectable by spectrofluorometry.

Rodríguez EJ, Debouck C, Deckman IC, Abu-Soud H, Raushel FM, Meek TD.

Biochemistry. 1993 Apr 13;32(14):3557-63.

PMID:
8466899
15.

Identification of the herpes simplex virus-1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products.

DiIanni CL, Drier DA, Deckman IC, McCann PJ 3rd, Liu F, Roizman B, Colonno RJ, Cordingley MG.

J Biol Chem. 1993 Jan 25;268(3):2048-51.

17.

Use of protein unfolding studies to determine the conformational and dimeric stabilities of HIV-1 and SIV proteases.

Grant SK, Deckman IC, Culp JS, Minnich MD, Brooks IS, Hensley P, Debouck C, Meek TD.

Biochemistry. 1992 Oct 6;31(39):9491-501.

PMID:
1390732
18.

Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease.

Grant SK, Deckman IC, Minnich MD, Culp J, Franklin S, Dreyer GB, Tomaszek TA Jr, Debouck C, Meek TD.

Biochemistry. 1991 Aug 27;30(34):8424-34.

PMID:
1883829
19.
20.

Physical studies of ribosomal protein-RNA interactions.

Draper DE, Deckman IC, Vartikar JV.

Methods Enzymol. 1988;164:203-20. No abstract available.

PMID:
3071663
22.

S4-alpha mRNA translation repression complex. I. Thermodynamics of formation.

Deckman IC, Draper DE, Thomas MS.

J Mol Biol. 1987 Jul 20;196(2):313-22.

PMID:
2443719
23.

Specific interaction between ribosomal protein S4 and the alpha operon messenger RNA.

Deckman IC, Draper DE.

Biochemistry. 1985 Dec 31;24(27):7860-5.

PMID:
3912010

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