Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 80

1.

PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching.

Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S.

PLoS One. 2019 Mar 6;14(3):e0213383. doi: 10.1371/journal.pone.0213383. eCollection 2019.

2.

Transcription-dependent regulation of replication dynamics modulates genome stability.

Blin M, Le Tallec B, Nähse V, Schmidt M, Brossas C, Millot GA, Prioleau MN, Debatisse M.

Nat Struct Mol Biol. 2019 Jan;26(1):58-66. doi: 10.1038/s41594-018-0170-1. Epub 2018 Dec 31.

PMID:
30598553
3.

A journey with common fragile sites: From S phase to telophase.

Debatisse M, Rosselli F.

Genes Chromosomes Cancer. 2019 May;58(5):305-316. doi: 10.1002/gcc.22704. Epub 2018 Dec 21. Review.

PMID:
30387289
4.

Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2.

Mendez-Bermudez A, Lototska L, Bauwens S, Giraud-Panis MJ, Croce O, Jamet K, Irizar A, Mowinckel M, Koundrioukoff S, Nottet N, Almouzni G, Teulade-Fichou MP, Schertzer M, Perderiset M, Londoño-Vallejo A, Debatisse M, Gilson E, Ye J.

Mol Cell. 2018 May 3;70(3):449-461.e5. doi: 10.1016/j.molcel.2018.03.036.

5.

FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells.

Pentzold C, Shah SA, Hansen NR, Le Tallec B, Seguin-Orlando A, Debatisse M, Lisby M, Oestergaard VH.

Nucleic Acids Res. 2018 Feb 16;46(3):1280-1294. doi: 10.1093/nar/gkx1260.

6.

The impact of replication stress on replication dynamics and DNA damage in vertebrate cells.

Técher H, Koundrioukoff S, Nicolas A, Debatisse M.

Nat Rev Genet. 2017 Sep;18(9):535-550. doi: 10.1038/nrg.2017.46. Epub 2017 Jul 17. Review.

PMID:
28714480
7.

PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1.

Cabrera E, Hernández-Pérez S, Koundrioukoff S, Debatisse M, Kim D, Smolka MB, Freire R, Gillespie DA.

Oncogene. 2017 Feb 2;36(5):678-686. doi: 10.1038/onc.2016.239. Epub 2016 Jul 4.

PMID:
27375025
8.

Variability of gait speed during six minutes walking test in COPD and cystic fibrosis patients.

Reychler G, Debatisse M, Lebecque P, Pieters T, Liistro G, Gohy S.

Gait Posture. 2016 Sep;49:36-40. doi: 10.1016/j.gaitpost.2016.06.007. Epub 2016 Jun 8.

PMID:
27362278
9.

USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication.

Hernández-Pérez S, Cabrera E, Amoedo H, Rodríguez-Acebes S, Koundrioukoff S, Debatisse M, Méndez J, Freire R.

Mol Oncol. 2016 Oct;10(8):1196-206. doi: 10.1016/j.molonc.2016.05.008. Epub 2016 Jun 3.

10.

Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress.

Wilhelm T, Ragu S, Magdalou I, Machon C, Dardillac E, Técher H, Guitton J, Debatisse M, Lopez BS.

PLoS Genet. 2016 May 2;12(5):e1006007. doi: 10.1371/journal.pgen.1006007. eCollection 2016 May.

11.

Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage.

Técher H, Koundrioukoff S, Carignon S, Wilhelm T, Millot GA, Lopez BS, Brison O, Debatisse M.

Cell Rep. 2016 Feb 9;14(5):1114-1127. doi: 10.1016/j.celrep.2015.12.093. Epub 2016 Jan 21.

12.

Loss of maintenance DNA methylation results in abnormal DNA origin firing during DNA replication.

Haruta M, Shimada M, Nishiyama A, Johmura Y, Le Tallec B, Debatisse M, Nakanishi M.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):960-6. doi: 10.1016/j.bbrc.2015.12.090. Epub 2015 Dec 22.

PMID:
26721438
13.

TIPIN depletion leads to apoptosis in breast cancer cells.

Baldeyron C, Brisson A, Tesson B, Némati F, Koundrioukoff S, Saliba E, De Koning L, Martel E, Ye M, Rigaill G, Meseure D, Nicolas A, Gentien D, Decaudin D, Debatisse M, Depil S, Cruzalegui F, Pierré A, Roman-Roman S, Tucker GC, Dubois T.

Mol Oncol. 2015 Oct;9(8):1580-98. doi: 10.1016/j.molonc.2015.04.010. Epub 2015 May 9.

14.

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.

Vogt N, Gibaud A, Lemoine F, de la Grange P, Debatisse M, Malfoy B.

Nucleic Acids Res. 2014 Dec 1;42(21):13194-205. doi: 10.1093/nar/gku1101. Epub 2014 Nov 6.

15.

Updating the mechanisms of common fragile site instability: how to reconcile the different views?

Le Tallec B, Koundrioukoff S, Wilhelm T, Letessier A, Brison O, Debatisse M.

Cell Mol Life Sci. 2014 Dec;71(23):4489-94. doi: 10.1007/s00018-014-1720-2. Epub 2014 Sep 24. Review.

16.

The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability.

Miotto B, Chibi M, Xie P, Koundrioukoff S, Moolman-Smook H, Pugh D, Debatisse M, He F, Zhang L, Defossez PA.

Cell Rep. 2014 Apr 24;7(2):575-587. doi: 10.1016/j.celrep.2014.03.030. Epub 2014 Apr 13.

17.

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.

Wilhelm T, Magdalou I, Barascu A, Técher H, Debatisse M, Lopez BS.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):763-8. doi: 10.1073/pnas.1311520111. Epub 2013 Dec 17.

18.

From the replicon to replication programs in space and time: regulation of DNA replication and implications for genomic instability.

Ostankovitch M, Debatisse M.

J Mol Biol. 2013 Nov 29;425(23):4659-62. doi: 10.1016/j.jmb.2013.10.023. No abstract available.

19.

Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes.

Le Tallec B, Millot GA, Blin ME, Brison O, Dutrillaux B, Debatisse M.

Cell Rep. 2013 Aug 15;4(3):420-8. doi: 10.1016/j.celrep.2013.07.003. Epub 2013 Aug 1.

20.

Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity.

Koundrioukoff S, Carignon S, Técher H, Letessier A, Brison O, Debatisse M.

PLoS Genet. 2013;9(7):e1003643. doi: 10.1371/journal.pgen.1003643. Epub 2013 Jul 18.

21.

Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.

Gibaud A, Vogt N, Brison O, Debatisse M, Malfoy B.

Nucleic Acids Res. 2013 Sep;41(17):8210-9. doi: 10.1093/nar/gkt566. Epub 2013 Jul 2.

22.

ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.

Naim V, Wilhelm T, Debatisse M, Rosselli F.

Nat Cell Biol. 2013 Aug;15(8):1008-15. doi: 10.1038/ncb2793. Epub 2013 Jun 30.

PMID:
23811686
23.

Replication dynamics: biases and robustness of DNA fiber analysis.

Técher H, Koundrioukoff S, Azar D, Wilhelm T, Carignon S, Brison O, Debatisse M, Le Tallec B.

J Mol Biol. 2013 Nov 29;425(23):4845-55. doi: 10.1016/j.jmb.2013.03.040. Epub 2013 Apr 1.

PMID:
23557832
24.

Molecular combing in the analysis of developmentally regulated amplified segments of Bradysia hygida.

Passos KJ, Togoro SY, Carignon S, Koundrioukoff S, Lachages AM, Debatisse M, Fernandez MA.

Genet Mol Res. 2012 Aug 6;11(3):2060-70. doi: 10.4238/2012.August.6.10.

25.

Common fragile sites: mechanisms of instability revisited.

Debatisse M, Le Tallec B, Letessier A, Dutrillaux B, Brison O.

Trends Genet. 2012 Jan;28(1):22-32. doi: 10.1016/j.tig.2011.10.003. Epub 2011 Nov 15. Review.

PMID:
22094264
26.

Molecular profiling of common fragile sites in human fibroblasts.

Le Tallec B, Dutrillaux B, Lachages AM, Millot GA, Brison O, Debatisse M.

Nat Struct Mol Biol. 2011 Nov 6;18(12):1421-3. doi: 10.1038/nsmb.2155.

PMID:
22056772
27.

[Genome: does a paucity of initiation events lead to fragility?].

Letessier A, Birnbaum D, Debatisse M, Chaffanet M.

Med Sci (Paris). 2011 Aug-Sep;27(8-9):707-9. doi: 10.1051/medsci/2011278011. Epub 2011 Aug 31. French. No abstract available.

28.

Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease.

Domínguez-Kelly R, Martín Y, Koundrioukoff S, Tanenbaum ME, Smits VA, Medema RH, Debatisse M, Freire R.

J Cell Biol. 2011 Aug 22;194(4):567-79. doi: 10.1083/jcb.201101047.

29.

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.

Chabosseau P, Buhagiar-Labarchède G, Onclercq-Delic R, Lambert S, Debatisse M, Brison O, Amor-Guéret M.

Nat Commun. 2011 Jun 28;2:368. doi: 10.1038/ncomms1363.

PMID:
21712816
30.

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.

Letessier A, Millot GA, Koundrioukoff S, Lachagès AM, Vogt N, Hansen RS, Malfoy B, Brison O, Debatisse M.

Nature. 2011 Feb 3;470(7332):120-3. doi: 10.1038/nature09745. Epub 2011 Jan 23.

PMID:
21258320
31.

Relationships linking amplification level to gene over-expression in gliomas.

Vogt N, Gibaud A, Almeida A, Ourliac-Garnier I, Debatisse M, Malfoy B.

PLoS One. 2010 Dec 8;5(12):e14249. doi: 10.1371/journal.pone.0014249.

32.

Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone.

Lubelsky Y, Sasaki T, Kuipers MA, Lucas I, Le Beau MM, Carignon S, Debatisse M, Prinz JA, Dennis JH, Gilbert DM.

Nucleic Acids Res. 2011 Apr;39(8):3141-55. doi: 10.1093/nar/gkq1276. Epub 2010 Dec 9.

33.

Replication origins oriGNAI3 and oriB of the mammalian AMPD2 locus nested in a region of straight DNA flanked by intrinsically bent DNA sites.

Balani VA, de Lima Neto QA, Takeda KI, Gimenes F, Fiorini A, Debatisse M, Fernandez MA.

BMB Rep. 2010 Nov;43(11):744-9. doi: 10.5483/BMBRep.2010.43.11.744.

34.

Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions.

Gay S, Lachages AM, Millot GA, Courbet S, Letessier A, Debatisse M, Brison O.

EMBO Rep. 2010 Sep;11(9):698-704. doi: 10.1038/embor.2010.112. Epub 2010 Jul 30.

35.

Extrachromosomal amplification mechanisms in a glioma with amplified sequences from multiple chromosome loci.

Gibaud A, Vogt N, Hadj-Hamou NS, Meyniel JP, Hupé P, Debatisse M, Malfoy B.

Hum Mol Genet. 2010 Apr 1;19(7):1276-85. doi: 10.1093/hmg/ddq004. Epub 2010 Jan 7.

PMID:
20056677
36.

Gene amplification mechanisms.

Debatisse M, Malfoy B.

Adv Exp Med Biol. 2005;570:343-61. doi: 10.1007/1-4020-3764-3_12. Review. No abstract available.

PMID:
18727507
37.

Replication fork movement sets chromatin loop size and origin choice in mammalian cells.

Courbet S, Gay S, Arnoult N, Wronka G, Anglana M, Brison O, Debatisse M.

Nature. 2008 Sep 25;455(7212):557-60. doi: 10.1038/nature07233. Epub 2008 Aug 17.

PMID:
18716622
38.

A homologous recombination defect affects replication-fork progression in mammalian cells.

Daboussi F, Courbet S, Benhamou S, Kannouche P, Zdzienicka MZ, Debatisse M, Lopez BS.

J Cell Sci. 2008 Jan 15;121(Pt 2):162-6. Epub 2007 Dec 18.

39.

Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells.

Quignon F, Rozier L, Lachages AM, Bieth A, Simili M, Debatisse M.

Oncogene. 2007 Jan 11;26(2):165-72. Epub 2006 Jul 10.

PMID:
16832348
40.

Gene amplification: yeast takes a turn.

Haber JE, Debatisse M.

Cell. 2006 Jun 30;125(7):1237-40. Review.

41.

Common fragile sites nested at the interfaces of early and late-replicating chromosome bands: cis acting components of the G2/M checkpoint?

Debatisse M, El Achkar E, Dutrillaux B.

Cell Cycle. 2006 Mar;5(6):578-81. Epub 2006 Mar 15. Review.

PMID:
16582603
42.

Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.

El Achkar E, Gerbault-Seureau M, Muleris M, Dutrillaux B, Debatisse M.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18069-74. Epub 2005 Dec 5.

43.
44.

Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.

Vogt N, Lefèvre SH, Apiou F, Dutrillaux AM, Cör A, Leuraud P, Poupon MF, Dutrillaux B, Debatisse M, Malfoy B.

Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11368-73. Epub 2004 Jul 21.

45.

Replication initiation in mammalian cells: changing preferences.

Debatisse M, Toledo F, Anglana M.

Cell Cycle. 2004 Jan;3(1):19-21. Review.

PMID:
14657657
46.
47.

How cells of repair-deficient mice handle chromosome breaks and proliferate as malignant survivors.

Debatisse M.

Trends Mol Med. 2002 Nov;8(11):503-5. No abstract available.

PMID:
12421678
49.

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I.

Ciullo M, Debily MA, Rozier L, Autiero M, Billault A, Mayau V, El Marhomy S, Guardiola J, Bernheim A, Coullin P, Piatier-Tonneau D, Debatisse M.

Hum Mol Genet. 2002 Nov 1;11(23):2887-94.

PMID:
12393800
50.

Mammalian recombination hot spot in a DNA loop anchorage region: a model for the study of common fragile sites.

Svetlova EY, Razin SV, Debatisse M.

J Cell Biochem Suppl. 2001;Suppl 36:170-8.

PMID:
11455582

Supplemental Content

Loading ...
Support Center