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Items: 1 to 50 of 204


Integrating soft and hard dose-volume constraints into hierarchical constrained IMRT optimization.

Mukherjee S, Hong L, Deasy JO, Zarepisheh M.

Med Phys. 2019 Nov 19. doi: 10.1002/mp.13908. [Epub ahead of print]


Patch-Based Generative Adversarial Neural Network Models for Head and Neck MR-Only Planning.

Klages P, Benslimane I, Riyahi S, Jiang J, Hunt M, Deasy JO, Veeraraghavan H, Tyagi N.

Med Phys. 2019 Nov 16. doi: 10.1002/mp.13927. [Epub ahead of print]


LDeform: Longitudinal deformation analysis for adaptive radiotherapy of lung cancer.

Nadeem S, Zhang P, Rimner A, Sonke JJ, Deasy JO, Tannenbaum A.

Med Phys. 2019 Nov 6. doi: 10.1002/mp.13907. [Epub ahead of print]


Organoids reveal that inherent radiosensitivity of small and large intestinal stem cells determines organ sensitivity.

Martin ML, Adileh M, Hsu KS, Hua G, Lee SG, Li C, Fuller JD, Rotolo JA, Bodo S, Klingler S, Haimovitz-Friedman A, Deasy JO, Fuks Z, Paty PB, Kolesnick RN.

Cancer Res. 2019 Nov 5. pii: canres.0312.2019. doi: 10.1158/0008-5472.CAN-19-0312. [Epub ahead of print]


Dose to the cardio-pulmonary system and treatment-induced electrocardiogram abnormalities in locally advanced non-small cell lung cancer.

Hotca A, Thor M, Deasy JO, Rimner A.

Clin Transl Radiat Oncol. 2019 Sep 21;19:96-102. doi: 10.1016/j.ctro.2019.09.003. eCollection 2019 Nov.


Are unsatisfactory outcomes after concurrent chemoradiotherapy for locally advanced non-small cell lung cancer due to treatment-related immunosuppression?

Thor M, Montovano M, Hotca A, Luo L, Jackson A, Wu AJ, Deasy JO, Rimner A.

Radiother Oncol. 2019 Oct 12. pii: S0167-8140(19)33009-9. doi: 10.1016/j.radonc.2019.07.016. [Epub ahead of print]


Dual-input tracer kinetic modeling of dynamic contrast-enhanced MRI in thoracic malignancies.

Lee SH, Rimner A, Deasy JO, Hunt MA, Tyagi N.

J Appl Clin Med Phys. 2019 Nov;20(11):169-188. doi: 10.1002/acm2.12740. Epub 2019 Oct 11.


Dynamic multiatlas selection-based consensus segmentation of head and neck structures from CT images.

Haq R, Berry SL, Deasy JO, Hunt M, Veeraraghavan H.

Med Phys. 2019 Dec;46(12):5612-5622. doi: 10.1002/mp.13854. Epub 2019 Oct 31.


Molecular phenotyping using networks, diffusion, and topology: soft tissue sarcoma.

Mathews JC, Pouryahya M, Moosmüller C, Kevrekidis YG, Deasy JO, Tannenbaum A.

Sci Rep. 2019 Sep 27;9(1):13982. doi: 10.1038/s41598-019-50300-2.


Robust and interpretable PAM50 reclassification exhibits survival advantage for myoepithelial and immune phenotypes.

Mathews JC, Nadeem S, Levine AJ, Pouryahya M, Deasy JO, Tannenbaum A.

NPJ Breast Cancer. 2019 Sep 9;5:30. doi: 10.1038/s41523-019-0124-8. eCollection 2019.


Toward predicting the evolution of lung tumors during radiotherapy observed on a longitudinal MR imaging study via a deep learning algorithm.

Wang C, Rimner A, Hu YC, Tyagi N, Jiang J, Yorke E, Riyahi S, Mageras G, Deasy JO, Zhang P.

Med Phys. 2019 Oct;46(10):4699-4707. doi: 10.1002/mp.13765. Epub 2019 Sep 6.


Cross-modality (CT-MRI) prior augmented deep learning for robust lung tumor segmentation from small MR datasets.

Jiang J, Hu YC, Tyagi N, Zhang P, Rimner A, Deasy JO, Veeraraghavan H.

Med Phys. 2019 Oct;46(10):4392-4404. doi: 10.1002/mp.13695. Epub 2019 Aug 20.


Optimal mass transport kinetic modeling for head and neck DCE-MRI: Initial analysis.

Elkin R, Nadeem S, LoCastro E, Paudyal R, Hatzoglou V, Lee NY, Shukla-Dave A, Deasy JO, Tannenbaum A.

Magn Reson Med. 2019 Dec;82(6):2314-2325. doi: 10.1002/mrm.27897. Epub 2019 Jul 4.


Impact of image preprocessing on the scanner dependence of multi-parametric MRI radiomic features and covariate shift in multi-institutional glioblastoma datasets.

Um H, Tixier F, Bermudez D, Deasy JO, Young RJ, Veeraraghavan H.

Phys Med Biol. 2019 Aug 21;64(16):165011. doi: 10.1088/1361-6560/ab2f44.


Spatial signature of dose patterns associated with acute radiation-induced lung damage in lung cancer patients treated with stereotactic body radiation therapy.

Palma G, Monti S, Thor M, Rimner A, Deasy JO, Cella L.

Phys Med Biol. 2019 Aug 7;64(15):155006. doi: 10.1088/1361-6560/ab2e16.


A theoretical investigation of adequate range uncertainty margins in proton treatment planning to preserve tumor control probability.

Taasti VT, Jeong J, Jackson A, Deasy JO.

Acta Oncol. 2019 Oct;58(10):1446-1450. doi: 10.1080/0284186X.2019.1627415. Epub 2019 Jun 26.


Toward personalized dose-prescription in locally advanced non-small cell lung cancer: Validation of published normal tissue complication probability models.

Thor M, Deasy J, Iyer A, Bendau E, Fontanella A, Apte A, Yorke E, Rimner A, Jackson A.

Radiother Oncol. 2019 Sep;138:45-51. doi: 10.1016/j.radonc.2019.05.011. Epub 2019 May 27.


Automated intensity modulated treatment planning: The expedited constrained hierarchical optimization (ECHO) system.

Zarepisheh M, Hong L, Zhou Y, Hun Oh J, Mechalakos JG, Hunt MA, Mageras GS, Deasy JO.

Med Phys. 2019 Jul;46(7):2944-2954. doi: 10.1002/mp.13572. Epub 2019 May 29.


Tolerance doses for late adverse events after hypofractionated radiotherapy for prostate cancer on trial NRG Oncology/RTOG 0415.

Thor M, Deasy JO, Paulus R, Robert Lee W, Amin MB, Bruner DW, Low DA, Shah AB, Malone SC, Michalski JM, Dayes IS, Seaward SA, Gore EM, Albert M, Pisansky TM, Faria SL, Chen Y, Koontz BF, Swanson GP, Pugh SL, Sandler HM.

Radiother Oncol. 2019 Jun;135:19-24. doi: 10.1016/j.radonc.2019.02.014. Epub 2019 Mar 5.


Enhancement of Long-Term External-Internal Correlation by Phase-Shift Detection and Correction Based on Concurrent External Bellows and Internal Navigator Signals.

Milewski AR, Olek D, Deasy JO, Rimner A, Li G.

Adv Radiat Oncol. 2019 Mar 1;4(2):377-389. doi: 10.1016/j.adro.2019.02.001. eCollection 2019 Apr-Jun.


Daily Fractionation of External Beam Accelerated Partial Breast Irradiation to 40 Gy Is Well Tolerated and Locally Effective.

Braunstein LZ, Thor M, Flynn J, Cost Z, Wilgucki M, Rosenbaum S, Zhang Z, Gillespie E, McCormick B, Khan A, Ho A, Cahlon O, Deasy JO, Powell SN.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):859-866. doi: 10.1016/j.ijrobp.2019.02.050. Epub 2019 Mar 7.


Preoperative MRI-radiomics features improve prediction of survival in glioblastoma patients over MGMT methylation status alone.

Tixier F, Um H, Bermudez D, Iyer A, Apte A, Graham MS, Nevel KS, Deasy JO, Young RJ, Veeraraghavan H.

Oncotarget. 2019 Jan 18;10(6):660-672. doi: 10.18632/oncotarget.26578. eCollection 2019 Jan 18.


Dosimetric evaluation of an atlas-based synthetic CT generation approach for MR-only radiotherapy of pelvis anatomy.

Farjam R, Tyagi N, Deasy JO, Hunt MA.

J Appl Clin Med Phys. 2019 Jan;20(1):101-109. doi: 10.1002/acm2.12501. Epub 2018 Nov 26.


Diffusion-weighted MRI of the lung at 3T evaluated using echo-planar-based and single-shot turbo spin-echo-based acquisition techniques for radiotherapy applications.

Tyagi N, Cloutier M, Zakian K, Deasy JO, Hunt M, Rimner A.

J Appl Clin Med Phys. 2019 Jan;20(1):284-292. doi: 10.1002/acm2.12493. Epub 2018 Nov 12.


Robust radiotherapy planning.

Unkelbach J, Alber M, Bangert M, Bokrantz R, Chan TCY, Deasy JO, Fredriksson A, Gorissen BL, van Herk M, Liu W, Mahmoudzadeh H, Nohadani O, Siebers JV, Witte M, Xu H.

Phys Med Biol. 2018 Nov 12;63(22):22TR02. doi: 10.1088/1361-6560/aae659. Review.


An Antitumor Immune Response Is Evoked by Partial-Volume Single-Dose Radiation in 2 Murine Models.

Markovsky E, Budhu S, Samstein RM, Li H, Russell J, Zhang Z, Drill E, Bodden C, Chen Q, Powell SN, Merghoub T, Wolchok JD, Humm J, Deasy JO, Haimovitz-Friedman A.

Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):697-708. doi: 10.1016/j.ijrobp.2018.10.009. Epub 2018 Oct 18.


Tumor-aware, Adversarial Domain Adaptation from CT to MRI for Lung Cancer Segmentation.

Jiang J, Hu YC, Tyagi N, Zhang P, Rimner A, Mageras GS, Deasy JO, Veeraraghavan H.

Med Image Comput Comput Assist Interv. 2018 Sep;11071:777-785. doi: 10.1007/978-3-030-00934-2_86.


Predictors of acute throat or esophageal patient reported pain during radiation therapy for head and neck cancer.

Gay HA, Oh JH, Apte AP, Daly MD, Adkins DR, Rich J, Oppelt PJ, Dyk PT, Mullen DF, Eschen L, Chin RI, Nussenbaum B, Haughey BH, Thorstad WL, Deasy JO.

Clin Transl Radiat Oncol. 2018 Sep 4;13:1-6. doi: 10.1016/j.ctro.2018.08.004. eCollection 2018 Nov.


A Systematic Post-QUANTEC Review of Tolerance Doses for Late Toxicity After Prostate Cancer Radiation Therapy.

Olsson CE, Jackson A, Deasy JO, Thor M.

Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1514-1532. doi: 10.1016/j.ijrobp.2018.08.015. Epub 2018 Aug 17.


Validating a Predictive Atlas of Tumor Shrinkage for Adaptive Radiotherapy of Locally Advanced Lung Cancer.

Zhang P, Yorke E, Mageras G, Rimner A, Sonke JJ, Deasy JO.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):978-986. doi: 10.1016/j.ijrobp.2018.05.056. Epub 2018 Jun 2.


Image-based Data Mining to Probe Dosimetric Correlates of Radiation-induced Trismus.

Beasley W, Thor M, McWilliam A, Green A, Mackay R, Slevin N, Olsson C, Pettersson N, Finizia C, Estilo C, Riaz N, Lee NY, Deasy JO, van Herk M.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1330-1338. doi: 10.1016/j.ijrobp.2018.05.054. Epub 2018 Jun 1.


Multiple Resolution Residually Connected Feature Streams for Automatic Lung Tumor Segmentation From CT Images.

Jiang J, Hu YC, Liu CJ, Halpenny D, Hellmann MD, Deasy JO, Mageras G, Veeraraghavan H.

IEEE Trans Med Imaging. 2019 Jan;38(1):134-144. doi: 10.1109/TMI.2018.2857800. Epub 2018 Jul 23.


Parotid gland fat related Magnetic Resonance image biomarkers improve prediction of late radiation-induced xerostomia.

van Dijk LV, Thor M, Steenbakkers RJHM, Apte A, Zhai TT, Borra R, Noordzij W, Estilo C, Lee N, Langendijk JA, Deasy JO, Sijtsema NM.

Radiother Oncol. 2018 Sep;128(3):459-466. doi: 10.1016/j.radonc.2018.06.012. Epub 2018 Jun 26.


Technical Note: Extension of CERR for computational radiomics: A comprehensive MATLAB platform for reproducible radiomics research.

Apte AP, Iyer A, Crispin-Ortuzar M, Pandya R, van Dijk LV, Spezi E, Thor M, Um H, Veeraraghavan H, Oh JH, Shukla-Dave A, Deasy JO.

Med Phys. 2018 Jun 13. doi: 10.1002/mp.13046. [Epub ahead of print]


Characterizing Cancer Drug Response and Biological Correlates: A Geometric Network Approach.

Pouryahya M, Oh JH, Mathews JC, Deasy JO, Tannenbaum AR.

Sci Rep. 2018 Apr 23;8(1):6402. doi: 10.1038/s41598-018-24679-3.


Correlation Between Tumor Metabolism and Semiquantitative Perfusion Magnetic Resonance Imaging Metrics in Non-Small Cell Lung Cancer.

Lee SH, Rimner A, Gelb E, Deasy JO, Hunt MA, Humm JL, Tyagi N.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):718-726. doi: 10.1016/j.ijrobp.2018.02.031. Epub 2018 Mar 2.


Image-guided radiotherapy reduces the risk of under-dosing high-risk prostate cancer extra-capsular disease and improves biochemical control.

Munck Af Rosenschold P, Zelefsky MJ, Apte AP, Jackson A, Oh JH, Shulman E, Desai N, Hunt M, Ghadjar P, Yorke E, Deasy JO.

Radiat Oncol. 2018 Apr 12;13(1):64. doi: 10.1186/s13014-018-0978-1.


Appearance Constrained Semi-Automatic Segmentation from DCE-MRI is Reproducible and Feasible for Breast Cancer Radiomics: A Feasibility Study.

Veeraraghavan H, Dashevsky BZ, Onishi N, Sadinski M, Morris E, Deasy JO, Sutton EJ.

Sci Rep. 2018 Mar 19;8(1):4838. doi: 10.1038/s41598-018-22980-9.


Inter-institutional analysis demonstrates the importance of lower than previously anticipated dose regions to prevent late rectal bleeding following prostate radiotherapy.

Thor M, Jackson A, Zelefsky MJ, Steineck G, Karlsdòttir A, Høyer M, Liu M, Nasser NJ, Petersen SE, Moiseenko V, Deasy JO.

Radiother Oncol. 2018 Apr;127(1):88-95. doi: 10.1016/j.radonc.2018.02.020. Epub 2018 Mar 9.


Machine Learning on a Genome-wide Association Study to Predict Late Genitourinary Toxicity After Prostate Radiation Therapy.

Lee S, Kerns S, Ostrer H, Rosenstein B, Deasy JO, Oh JH.

Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):128-135. doi: 10.1016/j.ijrobp.2018.01.054. Epub 2018 Jan 31.


Technical Note: Scintillation well counters and particle counting digital autoradiography devices can be used to detect activities associated with genomic profiling adequacy of biopsy specimens obtained after a low activity 18 F-FDG injection.

Kirov AS, Fanchon LM, Seiter D, Czmielewski C, Russell J, Dogan S, Carlin S, Pinker-Domenig K, Yorke E, Schmidtlein CR, Boyko V, Fujisawa S, Manova-Todorova K, Zanzonico P, Dauer L, Deasy JO, Humm JL, Solomon S.

Med Phys. 2018 May;45(5):2179-2185. doi: 10.1002/mp.12836. Epub 2018 Mar 23.


Radiomics analysis of pulmonary nodules in low-dose CT for early detection of lung cancer.

Choi W, Oh JH, Riyahi S, Liu CJ, Jiang F, Chen W, White C, Rimner A, Mechalakos JG, Deasy JO, Lu W.

Med Phys. 2018 Apr;45(4):1537-1549. doi: 10.1002/mp.12820. Epub 2018 Mar 12.


MRI features predictive of negative surgical margins in patients with HER2 overexpressing breast cancer undergoing breast conservation.

Dashevsky BZ, Oh JH, Apte AP, Bernard-Davila B, Morris EA, Deasy JO, Sutton EJ.

Sci Rep. 2018 Jan 10;8(1):315. doi: 10.1038/s41598-017-18758-0.


Predicting hypoxia status using a combination of contrast-enhanced computed tomography and [18F]-Fluorodeoxyglucose positron emission tomography radiomics features.

Crispin-Ortuzar M, Apte A, Grkovski M, Oh JH, Lee NY, Schöder H, Humm JL, Deasy JO.

Radiother Oncol. 2018 Apr;127(1):36-42. doi: 10.1016/j.radonc.2017.11.025. Epub 2017 Dec 19.


Simulating intrafraction prostate motion with a random walk model.

Pommer T, Oh JH, Munck Af Rosenschöld P, Deasy JO.

Adv Radiat Oncol. 2017 Mar 28;2(3):429-436. doi: 10.1016/j.adro.2017.03.005. eCollection 2017 Jul-Sep.


A Magnetic Resonance Imaging-based approach to quantify radiation-induced normal tissue injuries applied to trismus in head and neck cancer.

Thor M, Tyagi N, Hatzoglou V, Apte A, Saleh Z, Riaz N, Lee NY, Deasy JO.

Phys Imaging Radiat Oncol. 2017 Jan;1:34-40. doi: 10.1016/j.phro.2017.02.006. Epub 2017 Mar 25.


Spatial rectal dose/volume metrics predict patient-reported gastro-intestinal symptoms after radiotherapy for prostate cancer.

Casares-Magaz O, Muren LP, Moiseenko V, Petersen SE, Pettersson NJ, Høyer M, Deasy JO, Thor M.

Acta Oncol. 2017 Nov;56(11):1507-1513. doi: 10.1080/0284186X.2017.1370130. Epub 2017 Sep 8.


Beyond the margin recipe: the probability of correct target dosage and tumor control in the presence of a dose limiting structure.

Witte MG, Sonke JJ, Siebers J, Deasy JO, van Herk M.

Phys Med Biol. 2017 Sep 20;62(19):7874-7888. doi: 10.1088/1361-6560/aa87fe.


IMRT QA using machine learning: A multi-institutional validation.

Valdes G, Chan MF, Lim SB, Scheuermann R, Deasy JO, Solberg TD.

J Appl Clin Med Phys. 2017 Sep;18(5):279-284. doi: 10.1002/acm2.12161. Epub 2017 Aug 17.


A Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model.

Hajj C, Russell J, Hart CP, Goodman KA, Lowery MA, Haimovitz-Friedman A, Deasy JO, Humm JL.

Transl Oncol. 2017 Oct;10(5):760-765. doi: 10.1016/j.tranon.2017.06.010. Epub 2017 Jul 31.

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