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Items: 1 to 50 of 1187

1.

DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

Seeboth A, McCartney DL, Wang Y, Hillary RF, Stevenson AJ, Walker RM, Campbell A, Evans KL, McIntosh AM, Hägg S, Deary IJ, Marioni RE.

Clin Epigenetics. 2020 Mar 26;12(1):49. doi: 10.1186/s13148-020-00838-0.

2.

The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium.

Holleran L, Kelly S, Alloza C, Agartz I, Andreassen OA, Arango C, Banaj N, Calhoun V, Cannon D, Carr V, Corvin A, Glahn DC, Gur R, Hong E, Hoschl C, Howells FM, James A, Janssen J, Kochunov P, Lawrie SM, Liu J, Martinez C, McDonald C, Morris D, Mothersill D, Pantelis C, Piras F, Potkin S, Rasser PE, Roalf D, Rowland L, Satterthwaite T, Schall U, Spalletta G, Spaniel F, Stein DJ, Uhlmann A, Voineskos A, Zalesky A, van Erp TGM, Turner JA, Deary IJ, Thompson PM, Jahanshad N, Donohoe G.

Am J Psychiatry. 2020 Mar 26:appiajp201919030225. doi: 10.1176/appi.ajp.2019.19030225. [Epub ahead of print]

PMID:
32212855
3.

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.

Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe JR, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT.

Mol Psychiatry. 2020 Mar 16. doi: 10.1038/s41380-020-0689-5. [Epub ahead of print]

PMID:
32203155
4.

The genetic architecture of the human cerebral cortex.

Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR, Bernard M, Brouwer RM, Buimer EEL, Bülow R, Bürger C, Cannon DM, Chakravarty M, Chen Q, Cheung JW, Couvy-Duchesne B, Dale AM, Dalvie S, de Araujo TK, de Zubicaray GI, de Zwarte SMC, den Braber A, Doan NT, Dohm K, Ehrlich S, Engelbrecht HR, Erk S, Fan CC, Fedko IO, Foley SF, Ford JM, Fukunaga M, Garrett ME, Ge T, Giddaluru S, Goldman AL, Green MJ, Groenewold NA, Grotegerd D, Gurholt TP, Gutman BA, Hansell NK, Harris MA, Harrison MB, Haswell CC, Hauser M, Herms S, Heslenfeld DJ, Ho NF, Hoehn D, Hoffmann P, Holleran L, Hoogman M, Hottenga JJ, Ikeda M, Janowitz D, Jansen IE, Jia T, Jockwitz C, Kanai R, Karama S, Kasperaviciute D, Kaufmann T, Kelly S, Kikuchi M, Klein M, Knapp M, Knodt AR, Krämer B, Lam M, Lancaster TM, Lee PH, Lett TA, Lewis LB, Lopes-Cendes I, Luciano M, Macciardi F, Marquand AF, Mathias SR, Melzer TR, Milaneschi Y, Mirza-Schreiber N, Moreira JCV, Mühleisen TW, Müller-Myhsok B, Najt P, Nakahara S, Nho K, Olde Loohuis LM, Orfanos DP, Pearson JF, Pitcher TL, Pütz B, Quidé Y, Ragothaman A, Rashid FM, Reay WR, Redlich R, Reinbold CS, Repple J, Richard G, Riedel BC, Risacher SL, Rocha CS, Mota NR, Salminen L, Saremi A, Saykin AJ, Schlag F, Schmaal L, Schofield PR, Secolin R, Shapland CY, Shen L, Shin J, Shumskaya E, Sønderby IE, Sprooten E, Tansey KE, Teumer A, Thalamuthu A, Tordesillas-Gutiérrez D, Turner JA, Uhlmann A, Vallerga CL, van der Meer D, van Donkelaar MMJ, van Eijk L, van Erp TGM, van Haren NEM, van Rooij D, van Tol MJ, Veldink JH, Verhoef E, Walton E, Wang M, Wang Y, Wardlaw JM, Wen W, Westlye LT, Whelan CD, Witt SH, Wittfeld K, Wolf C, Wolfers T, Wu JQ, Yasuda CL, Zaremba D, Zhang Z, Zwiers MP, Artiges E, Assareh AA, Ayesa-Arriola R, Belger A, Brandt CL, Brown GG, Cichon S, Curran JE, Davies GE, Degenhardt F, Dennis MF, Dietsche B, Djurovic S, Doherty CP, Espiritu R, Garijo D, Gil Y, Gowland PA, Green RC, Häusler AN, Heindel W, Ho BC, Hoffmann WU, Holsboer F, Homuth G, Hosten N, Jack CR Jr, Jang M, Jansen A, Kimbrel NA, Kolskår K, Koops S, Krug A, Lim KO, Luykx JJ, Mathalon DH, Mather KA, Mattay VS, Matthews S, Mayoral Van Son J, McEwen SC, Melle I, Morris DW, Mueller BA, Nauck M, Nordvik JE, Nöthen MM, O'Leary DS, Opel N, Martinot MP, Pike GB, Preda A, Quinlan EB, Rasser PE, Ratnakar V, Reppermund S, Steen VM, Tooney PA, Torres FR, Veltman DJ, Voyvodic JT, Whelan R, White T, Yamamori H, Adams HHH, Bis JC, Debette S, Decarli C, Fornage M, Gudnason V, Hofer E, Ikram MA, Launer L, Longstreth WT, Lopez OL, Mazoyer B, Mosley TH, Roshchupkin GV, Satizabal CL, Schmidt R, Seshadri S, Yang Q; Alzheimer’s Disease Neuroimaging Initiative; CHARGE Consortium; EPIGEN Consortium; IMAGEN Consortium; SYS Consortium; Parkinson’s Progression Markers Initiative, Alvim MKM, Ames D, Anderson TJ, Andreassen OA, Arias-Vasquez A, Bastin ME, Baune BT, Beckham JC, Blangero J, Boomsma DI, Brodaty H, Brunner HG, Buckner RL, Buitelaar JK, Bustillo JR, Cahn W, Cairns MJ, Calhoun V, Carr VJ, Caseras X, Caspers S, Cavalleri GL, Cendes F, Corvin A, Crespo-Facorro B, Dalrymple-Alford JC, Dannlowski U, de Geus EJC, Deary IJ, Delanty N, Depondt C, Desrivières S, Donohoe G, Espeseth T, Fernández G, Fisher SE, Flor H, Forstner AJ, Francks C, Franke B, Glahn DC, Gollub RL, Grabe HJ, Gruber O, Håberg AK, Hariri AR, Hartman CA, Hashimoto R, Heinz A, Henskens FA, Hillegers MHJ, Hoekstra PJ, Holmes AJ, Hong LE, Hopkins WD, Hulshoff Pol HE, Jernigan TL, Jönsson EG, Kahn RS, Kennedy MA, Kircher TTJ, Kochunov P, Kwok JBJ, Le Hellard S, Loughland CM, Martin NG, Martinot JL, McDonald C, McMahon KL, Meyer-Lindenberg A, Michie PT, Morey RA, Mowry B, Nyberg L, Oosterlaan J, Ophoff RA, Pantelis C, Paus T, Pausova Z, Penninx BWJH, Polderman TJC, Posthuma D, Rietschel M, Roffman JL, Rowland LM, Sachdev PS, Sämann PG, Schall U, Schumann G, Scott RJ, Sim K, Sisodiya SM, Smoller JW, Sommer IE, St Pourcain B, Stein DJ, Toga AW, Trollor JN, Van der Wee NJA, van 't Ent D, Völzke H, Walter H, Weber B, Weinberger DR, Wright MJ, Zhou J, Stein JL, Thompson PM, Medland SE; Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group.

Science. 2020 Mar 20;367(6484). pii: eaay6690. doi: 10.1126/science.aay6690.

PMID:
32193296
5.

Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers.

Lund JB, Li S, Baumbach J, Christensen K, Li W, Mohammadnejad A, Pattie A, Marioni RE, Deary IJ, Tan Q.

J Gerontol A Biol Sci Med Sci. 2020 Mar 10. pii: glaa066. doi: 10.1093/gerona/glaa066. [Epub ahead of print]

PMID:
32154558
6.

Generational differences in loneliness and its psychological and sociodemographic predictors: an exploratory and confirmatory machine learning study.

Altschul D, Iveson M, Deary IJ.

Psychol Med. 2020 Mar 9:1-10. doi: 10.1017/S0033291719003933. [Epub ahead of print]

PMID:
32146913
7.

DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921.

Sibbett RA, Altschul DM, Marioni RE, Deary IJ, Starr JM, Russ TC.

BMC Psychiatry. 2020 Feb 28;20(1):91. doi: 10.1186/s12888-020-2469-9.

8.

Polygenic Architecture of Human Neuroanatomical Diversity.

Biton A, Traut N, Poline JB, Aribisala BS, Bastin ME, Bülow R, Cox SR, Deary IJ, Fukunaga M, Grabe HJ, Hagenaars S, Hashimoto R, Kikuchi M, Muñoz Maniega S, Nauck M, Royle NA, Teumer A, Valdés Hernández M, Völker U, Wardlaw JM, Wittfeld K, Yamamori H; Alzheimer’s Disease Neuroimaging Initiative, Bourgeron T, Toro R.

Cereb Cortex. 2020 Feb 28. pii: bhz241. doi: 10.1093/cercor/bhz241. [Epub ahead of print]

PMID:
32109272
10.

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age.

Harris SE, Cox SR, Bell S, Marioni RE, Prins BP, Pattie A, Corley J, Muñoz Maniega S, Valdés Hernández M, Morris Z, John S, Bronson PG, Tucker-Drob EM, Starr JM, Bastin ME, Wardlaw JM, Butterworth AS, Deary IJ.

Nat Commun. 2020 Feb 10;11(1):800. doi: 10.1038/s41467-019-14161-7.

11.

Education, intelligence and Alzheimer's disease: evidence from a multivariable two-sample Mendelian randomization study.

Anderson EL, Howe LD, Wade KH, Ben-Shlomo Y, Hill WD, Deary IJ, Sanderson EC, Zheng J, Korologou-Linden R, Stergiakouli E, Davey Smith G, Davies NM, Hemani G.

Int J Epidemiol. 2020 Jan 31. pii: dyz280. doi: 10.1093/ije/dyz280. [Epub ahead of print]

PMID:
32003800
12.

Attitudes to ageing, biomarkers of ageing and mortality: the Lothian Birth Cohort 1936.

McLachlan KJJ, Cole JH, Harris SE, Marioni RE, Deary IJ, Gale CR.

J Epidemiol Community Health. 2020 Apr;74(4):377-383. doi: 10.1136/jech-2019-213462. Epub 2020 Jan 28.

13.

Fluctuating asymmetry in brain structure and general intelligence in 73-year-olds.

Moodie JE, Ritchie SJ, Cox SR, Harris MA, Muñoz Maniega S, Valdés Hernández MC, Pattie A, Corley J, Bastin ME, Starr JM, Wardlaw JM, Deary IJ.

Intelligence. 2020 Jan-Feb;78:101407. doi: 10.1016/j.intell.2019.101407.

14.

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.

Coleman JRI, Peyrot WJ, Purves KL, Davis KAS, Rayner C, Choi SW, Hübel C, Gaspar HA, Kan C, Van der Auwera S, Adams MJ, Lyall DM, Choi KW; on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dunn EC, Vassos E, Danese A, Maughan B, Grabe HJ, Lewis CM, O'Reilly PF, McIntosh AM, Smith DJ, Wray NR, Hotopf M, Eley TC, Breen G.

Mol Psychiatry. 2020 Jan 23. doi: 10.1038/s41380-019-0546-6. [Epub ahead of print]

PMID:
31969693
15.

Associations Between Declining Physical and Cognitive Functions in the Lothian Birth Cohort 1936.

Okely JA, Deary IJ.

J Gerontol A Biol Sci Med Sci. 2020 Jan 20. pii: glaa023. doi: 10.1093/gerona/glaa023. [Epub ahead of print]

PMID:
31957799
16.

Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation.

Wragg D, Liu Q, Lin Z, Riggio V, Pugh CA, Beveridge AJ, Brown H, Hume DA, Harris SE, Deary IJ, Tenesa A, Prendergast JGD.

Nat Commun. 2020 Jan 17;11(1):343. doi: 10.1038/s41467-019-13762-6.

17.

The effect of network thresholding and weighting on structural brain networks in the UK Biobank.

Buchanan CR, Bastin ME, Ritchie SJ, Liewald DC, Madole JW, Tucker-Drob EM, Deary IJ, Cox SR.

Neuroimage. 2020 May 1;211:116443. doi: 10.1016/j.neuroimage.2019.116443. Epub 2020 Jan 10.

18.

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.

Coleman JRI, Gaspar HA, Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Breen G.

Biol Psychiatry. 2019 Nov 1. pii: S0006-3223(19)31813-X. doi: 10.1016/j.biopsych.2019.10.015. [Epub ahead of print]

PMID:
31926635
19.

An epigenome-wide association study of sex-specific chronological ageing.

McCartney DL, Zhang F, Hillary RF, Zhang Q, Stevenson AJ, Walker RM, Bermingham ML, Boutin T, Morris SW, Campbell A, Murray AD, Whalley HC, Porteous DJ, Hayward C, Evans KL, Chandra T, Deary IJ, McIntosh AM, Yang J, Visscher PM, McRae AF, Marioni RE.

Genome Med. 2019 Dec 31;12(1):1. doi: 10.1186/s13073-019-0693-z.

20.

Computational quantification of brain perivascular space morphologies: Associations with vascular risk factors and white matter hyperintensities. A study in the Lothian Birth Cohort 1936.

Ballerini L, Booth T, Valdés Hernández MDC, Wiseman S, Lovreglio R, Muñoz Maniega S, Morris Z, Pattie A, Corley J, Gow A, Bastin ME, Deary IJ, Wardlaw J.

Neuroimage Clin. 2020;25:102120. doi: 10.1016/j.nicl.2019.102120. Epub 2019 Dec 9.

22.

Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.

Hill WD, Davies NM, Ritchie SJ, Skene NG, Bryois J, Bell S, Di Angelantonio E, Roberts DJ, Xueyi S, Davies G, Liewald DCM, Porteous DJ, Hayward C, Butterworth AS, McIntosh AM, Gale CR, Deary IJ.

Nat Commun. 2019 Dec 16;10(1):5741. doi: 10.1038/s41467-019-13585-5.

23.

Navigating the landscape of non-health administrative data in Scotland: A researcher's narrative.

Iveson MH, Deary IJ.

Version 2. Wellcome Open Res. 2019 Oct 21 [revised 2019 Jan 1];4:97. doi: 10.12688/wellcomeopenres.15336.2. eCollection 2019.

24.

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.

Jia T, Chu C, Liu Y, van Dongen J, Papastergios E, Armstrong NJ, Bastin ME, Carrillo-Roa T, den Braber A, Harris M, Jansen R, Liu J, Luciano M, Ori APS, Roiz Santiañez R, Ruggeri B, Sarkisyan D, Shin J, Sungeun K, Tordesillas Gutiérrez D, Van't Ent D, Ames D, Artiges E, Bakalkin G, Banaschewski T, Bokde ALW, Brodaty H, Bromberg U, Brouwer R, Büchel C, Burke Quinlan E, Cahn W, de Zubicaray GI, Ehrlich S, Ekström TJ, Flor H, Fröhner JH, Frouin V, Garavan H, Gowland P, Heinz A, Hoare J, Ittermann B, Jahanshad N, Jiang J, Kwok JB, Martin NG, Martinot JL, Mather KA, McMahon KL, McRae AF, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Sämann PG, Schofield PR, Smolka MN, Stein DJ, Strike LT, Teeuw J, Thalamuthu A, Trollor J, Walter H, Wardlaw JM, Wen W, Whelan R, Apostolova LG, Binder EB, Boomsma DI, Calhoun V, Crespo-Facorro B, Deary IJ, Hulshoff Pol H, Ophoff RA, Pausova Z, Sachdev PS, Saykin A, Wright MJ, Thompson PM, Schumann G, Desrivières S.

Mol Psychiatry. 2019 Dec 6. doi: 10.1038/s41380-019-0605-z. [Epub ahead of print]

PMID:
31811260
25.

An epigenetic predictor of death captures multi-modal measures of brain health.

Hillary RF, Stevenson AJ, Cox SR, McCartney DL, Harris SE, Seeboth A, Higham J, Sproul D, Taylor AM, Redmond P, Corley J, Pattie A, Hernández MDCV, Muñoz-Maniega S, Bastin ME, Wardlaw JM, Horvath S, Ritchie CW, Spires-Jones TL, McIntosh AM, Evans KL, Deary IJ, Marioni RE.

Mol Psychiatry. 2019 Dec 3. doi: 10.1038/s41380-019-0616-9. [Epub ahead of print]

PMID:
31796892
26.

Loss-of-Function Mutations in the ALPL Gene Presenting with Adult Onset Osteoporosis and Low Serum Concentrations of Total Alkaline Phosphatase.

Alonso N, Larraz-Prieto B, Berg K, Lambert Z, Redmond P, Harris SE, Deary IJ, Pugh C, Prendergast J, Ralston SH.

J Bone Miner Res. 2019 Dec 2. doi: 10.1002/jbmr.3928. [Epub ahead of print]

PMID:
31793067
27.

Structural brain imaging correlates of general intelligence in UK Biobank.

Cox SR, Ritchie SJ, Fawns-Ritchie C, Tucker-Drob EM, Deary IJ.

Intelligence. 2019 Sep-Oct;76:101376. doi: 10.1016/j.intell.2019.101376.

28.

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life.

Stevenson AJ, McCartney DL, Hillary RF, Redmond P, Taylor AM, Zhang Q, McRae AF, Spires-Jones TL, McIntosh AM, Deary IJ, Marioni RE.

Transl Psychiatry. 2019 Nov 28;9(1):323. doi: 10.1038/s41398-019-0657-5.

29.

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population.

Clarke TK, Adams MJ, Howard DM, Xia C, Davies G, Hayward C, Campbell A, Padmanabhan S, Smith BH, Murray A, Porteous D, Deary IJ, McIntosh AM.

Mol Psychiatry. 2019 Nov 25. doi: 10.1038/s41380-019-0607-x. [Epub ahead of print]

PMID:
31767999
30.

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions.

Halachev M, Meynert A, Taylor MS, Vitart V, Kerr SM, Klaric L; S. G. P. Consortium, Aitman TJ, Haley CS, Prendergast JG, Pugh C, Hume DA, Harris SE, Liewald DC, Deary IJ, Semple CA, Wilson JF.

PLoS Genet. 2019 Nov 25;15(11):e1008480. doi: 10.1371/journal.pgen.1008480. eCollection 2019 Nov.

31.

Playing Analog Games Is Associated With Reduced Declines in Cognitive Function: A 68-Year Longitudinal Cohort Study.

Altschul DM, Deary IJ.

J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):474-482. doi: 10.1093/geronb/gbz149.

32.

The MMPI factor scales and risk of death in men during 45 years of follow-up: The Western Electric study.

Weiss A, Costa PT, Deary IJ, Garside DB, Stamler J.

Psychol Aging. 2020 Feb;35(1):97-111. doi: 10.1037/pag0000421. Epub 2019 Nov 11.

PMID:
31714099
33.

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.

Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, González MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del Río Noriega F, Perez FP, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Küstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, Müller-Myhsok B, Forstner AJ, Nöthen MM, Rietschel M.

Mol Psychiatry. 2019 Nov 11. doi: 10.1038/s41380-019-0558-2. [Epub ahead of print]

PMID:
31712721
34.

Cross-sectional associations between personality traits and device-based measures of step count and sedentary behaviour in older age: the Lothian Birth Cohort 1936.

Čukić I, Gale CR, Chastin SFM, Dall PM, Dontje ML, Skelton DA, Deary IJ; Seniors USP Team.

BMC Geriatr. 2019 Nov 10;19(1):302. doi: 10.1186/s12877-019-1328-3.

35.

Physical frailty and decline in general and specific cognitive abilities: the Lothian Birth Cohort 1936.

Gale C, Ritchie SJ, Starr JM, Deary IJ.

J Epidemiol Community Health. 2020 Feb;74(2):108-113. doi: 10.1136/jech-2019-213280. Epub 2019 Nov 5.

36.

Associations between Brief Resilience Scale scores and ageing-related domains in the Lothian Birth Cohort 1936.

Taylor AM, Ritchie SJ, Madden C, Deary IJ.

Psychol Aging. 2019 Nov 4. doi: 10.1037/pag0000419. [Epub ahead of print]

PMID:
31682139
37.

Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai JF, Corre T, Cousminer DL, Dekker AM, Eccles DA, van Eijk KR, Fuchsberger C, Gao H, Germain M, Gordon SD, de Haan HG, Harris SE, Hofer E, Huerta-Chagoya A, Igartua C, Jansen IE, Jia Y, Kacprowski T, Karlsson T, Kleber ME, Li SA, Li-Gao R, Mahajan A, Matsuda K, Meidtner K, Meng W, Montasser ME, van der Most PJ, Munz M, Nutile T, Palviainen T, Prasad G, Prasad RB, Priyanka TDS, Rizzi F, Salvi E, Sapkota BR, Shriner D, Skotte L, Smart MC, Smith AV, van der Spek A, Spracklen CN, Strawbridge RJ, Tajuddin SM, Trompet S, Turman C, Verweij N, Viberti C, Wang L, Warren HR, Wootton RE, Yanek LR, Yao J, Yousri NA, Zhao W, Adeyemo AA, Afaq S, Aguilar-Salinas CA, Akiyama M, Albert ML, Allison MA, Alver M, Aung T, Azizi F, Bentley AR, Boeing H, Boerwinkle E, Borja JB, de Borst GJ, Bottinger EP, Broer L, Campbell H, Chanock S, Chee ML, Chen G, Chen YI, Chen Z, Chiu YF, Cocca M, Collins FS, Concas MP, Corley J, Cugliari G, van Dam RM, Damulina A, Daneshpour MS, Day FR, Delgado GE, Dhana K, Doney ASF, Dörr M, Doumatey AP, Dzimiri N, Ebenesersdóttir SS, Elliott J, Elliott P, Ewert R, Felix JF, Fischer K, Freedman BI, Girotto G, Goel A, Gögele M, Goodarzi MO, Graff M, Granot-Hershkovitz E, Grodstein F, Guarrera S, Gudbjartsson DF, Guity K, Gunnarsson B, Guo Y, Hagenaars SP, Haiman CA, Halevy A, Harris TB, Hedayati M, van Heel DA, Hirata M, Höfer I, Hsiung CA, Huang J, Hung YJ, Ikram MA, Jagadeesan A, Jousilahti P, Kamatani Y, Kanai M, Kerrison ND, Kessler T, Khaw KT, Khor CC, de Kleijn DPV, Koh WP, Kolcic I, Kraft P, Krämer BK, Kutalik Z, Kuusisto J, Langenberg C, Launer LJ, Lawlor DA, Lee IT, Lee WJ, Lerch MM, Li L, Liu J, Loh M, London SJ, Loomis S, Lu Y, Luan J, Mägi R, Manichaikul AW, Manunta P, Másson G, Matoba N, Mei XW, Meisinger C, Meitinger T, Mezzavilla M, Milani L, Millwood IY, Momozawa Y, Moore A, Morange PE, Moreno-Macías H, Mori TA, Morrison AC, Muka T, Murakami Y, Murray AD, de Mutsert R, Mychaleckyj JC, Nalls MA, Nauck M, Neville MJ, Nolte IM, Ong KK, Orozco L, Padmanabhan S, Pálsson G, Pankow JS, Pattaro C, Pattie A, Polasek O, Poulter N, Pramstaller PP, Quintana-Murci L, Räikkönen K, Ralhan S, Rao DC, van Rheenen W, Rich SS, Ridker PM, Rietveld CA, Robino A, van Rooij FJA, Ruggiero D, Saba Y, Sabanayagam C, Sabater-Lleal M, Sala CF, Salomaa V, Sandow K, Schmidt H, Scott LJ, Scott WR, Sedaghati-Khayat B, Sennblad B, van Setten J, Sever PJ, Sheu WH, Shi Y, Shrestha S, Shukla SR, Sigurdsson JK, Sikka TT, Singh JR, Smith BH, Stančáková A, Stanton A, Starr JM, Stefansdottir L, Straker L, Sulem P, Sveinbjornsson G, Swertz MA, Taylor AM, Taylor KD, Terzikhan N, Tham YC, Thorleifsson G, Thorsteinsdottir U, Tillander A, Tracy RP, Tusié-Luna T, Tzoulaki I, Vaccargiu S, Vangipurapu J, Veldink JH, Vitart V, Völker U, Vuoksimaa E, Wakil SM, Waldenberger M, Wander GS, Wang YX, Wareham NJ, Wild S, Yajnik CS, Yuan JM, Zeng L, Zhang L, Zhou J, Amin N, Asselbergs FW, Bakker SJL, Becker DM, Lehne B, Bennett DA, van den Berg LH, Berndt SI, Bharadwaj D, Bielak LF, Bochud M, Boehnke M, Bouchard C, Bradfield JP, Brody JA, Campbell A, Carmi S, Caulfield MJ, Cesarini D, Chambers JC, Chandak GR, Cheng CY, Ciullo M, Cornelis M, Cusi D, Smith GD, Deary IJ, Dorajoo R, van Duijn CM, Ellinghaus D, Erdmann J, Eriksson JG, Evangelou E, Evans MK, Faul JD, Feenstra B, Feitosa M, Foisy S, Franke A, Friedlander Y, Gasparini P, Gieger C, Gonzalez C, Goyette P, Grant SFA, Griffiths LR, Groop L, Gudnason V, Gyllensten U, Hakonarson H, Hamsten A, van der Harst P, Heng CK, Hicks AA, Hochner H, Huikuri H, Hunt SC, Jaddoe VWV, De Jager PL, Johannesson M, Johansson Å, Jonas JB, Jukema JW, Junttila J, Kaprio J, Kardia SLR, Karpe F, Kumari M, Laakso M, van der Laan SW, Lahti J, Laudes M, Lea RA, Lieb W, Lumley T, Martin NG, März W, Matullo G, McCarthy MI, Medland SE, Merriman TR, Metspalu A, Meyer BF, Mohlke KL, Montgomery GW, Mook-Kanamori D, Munroe PB, North KE, Nyholt DR, O'connell JR, Ober C, Oldehinkel AJ, Palmas W, Palmer C, Pasterkamp GG, Patin E, Pennell CE, Perusse L, Peyser PA, Pirastu M, Polderman TJC, Porteous DJ, Posthuma D, Psaty BM, Rioux JD, Rivadeneira F, Rotimi C, Rotter JI, Rudan I, Den Ruijter HM, Sanghera DK, Sattar N, Schmidt R, Schulze MB, Schunkert H, Scott RA, Shuldiner AR, Sim X, Small N, Smith JA, Sotoodehnia N, Tai ES, Teumer A, Timpson NJ, Toniolo D, Tregouet DA, Tuomi T, Vollenweider P, Wang CA, Weir DR, Whitfield JB, Wijmenga C, Wong TY, Wright J, Yang J, Yu L, Zemel BS, Zonderman AB, Perola M, Magnusson PKE, Uitterlinden AG, Kooner JS, Chasman DI, Loos RJF, Franceschini N, Franke L, Haley CS, Hayward C, Walters RG, Perry JRB, Esko T, Helgason A, Stefansson K, Joshi PK, Kubo M, Wilson JF.

Nat Commun. 2019 Oct 31;10(1):4957. doi: 10.1038/s41467-019-12283-6.

38.

Genetic correlations between pain phenotypes and depression and neuroticism.

Meng W, Adams MJ, Reel P, Rajendrakumar A, Huang Y, Deary IJ, Palmer CNA, McIntosh AM, Smith BH.

Eur J Hum Genet. 2020 Mar;28(3):358-366. doi: 10.1038/s41431-019-0530-2. Epub 2019 Oct 29.

39.

Genetic architecture of subcortical brain structures in 38,851 individuals.

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S, Arias-Vasquez A, Chauhan G, Athanasiu L, Rentería ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santiañez R, Kraemer B, Håberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Pütz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Sämann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdés Hernández MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR Jr, Schofield PR, Mühleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jönsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT Jr, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaître H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Müller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Völzke H, Wright MJ, van 't Ent D, Nöthen MM, Ophoff RA, Buitelaar JK, Fernández G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA.

Nat Genet. 2019 Nov;51(11):1624-1636. doi: 10.1038/s41588-019-0511-y. Epub 2019 Oct 21.

PMID:
31636452
40.

Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study.

Bressler J, Marioni RE, Walker RM, Xia R, Gottesman RF, Windham BG, Grove ML, Guan W, Pankow JS, Evans KL, Mcintosh AM, Deary IJ, Mosley TH, Boerwinkle E, Fornage M.

J Gerontol A Biol Sci Med Sci. 2020 Feb 14;75(3):473-480. doi: 10.1093/gerona/glz245.

PMID:
31630168
41.

Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people.

Calvin CM, Wilkinson T, Starr JM, Sudlow C, Hagenaars SP, Harris SE, Schnier C, Davies G, Fawns-Ritchie C, Gale CR, Gallacher J, Deary IJ.

Alzheimers Dement. 2019 Dec;15(12):1546-1557. doi: 10.1016/j.jalz.2019.07.014. Epub 2019 Oct 13.

PMID:
31619348
42.

Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease.

Veluchamy A, Ballerini L, Vitart V, Schraut KE, Kirin M, Campbell H, Joshi PK, Relan D, Harris S, Brown E, Vaidya SS, Dhillon B, Zhou K, Pearson ER, Hayward C, Polasek O, Deary IJ, MacGillivray T, Wilson JF, Trucco E, Palmer CNA, Doney ASF.

Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2542-2552. doi: 10.1161/ATVBAHA.119.312552. Epub 2019 Oct 10.

43.

Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936.

Corley J, Cox SR, Harris SE, Hernandez MV, Maniega SM, Bastin ME, Wardlaw JM, Starr JM, Marioni RE, Deary IJ.

Transl Psychiatry. 2019 Oct 7;9(1):248. doi: 10.1038/s41398-019-0576-5.

44.

Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition.

Adams MJ, Howard DM, Luciano M, Clarke TK, Davies G, Hill WD; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Smith D, Deary IJ, Porteous DJ, McIntosh AM.

Psychol Med. 2019 Oct 2:1-10. doi: 10.1017/S0033291719002629. [Epub ahead of print]

PMID:
31576797
45.

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.

Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, Dannlowski U, Direk N, Dunn EC, Forstner AJ, de Geus EJC, Grabe HJ, Hamilton SP, Jones I, Jones LA, Knowles JA, Kutalik Z, Levinson DF, Lewis G, Lind PA, Lucae S, Magnusson PK, McGuffin P, McIntosh AM, Milaneschi Y, Mors O, Mostafavi S, Müller-Myhsok B, Pedersen NL, Penninx BWJH, Potash JB, Preisig M, Ripke S, Shi J, Shyn SI, Smoller JW, Streit F, Sullivan PF, Tiemeier H, Uher R, Van der Auwera S, Weissman MM; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, O'Reilly PF, Lewis CM.

Biol Psychiatry. 2020 Mar 1;87(5):419-430. doi: 10.1016/j.biopsych.2019.06.031. Epub 2019 Aug 5.

46.

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Sikdar S, Joehanes R, Joubert BR, Xu CJ, Vives-Usano M, Rezwan FI, Felix JF, Ward JM, Guan W, Richmond RC, Brody JA, Küpers LK, Baïz N, Håberg SE, Smith JA, Reese SE, Aslibekyan S, Hoyo C, Dhingra R, Markunas CA, Xu T, Reynolds LM, Just AC, Mandaviya PR, Ghantous A, Bennett BD, Wang T, Consortium TB, Bakulski KM, Melen E, Zhao S, Jin J, Herceg Z, Meurs JV, Taylor JA, Baccarelli AA, Murphy SK, Liu Y, Munthe-Kaas MC, Deary IJ, Nystad W, Waldenberger M, Annesi-Maesano I, Conneely K, Jaddoe VW, Arnett D, Snieder H, Kardia SL, Relton CL, Ong KK, Ewart S, Moreno-Macias H, Romieu I, Sotoodehnia N, Fornage M, Motsinger-Reif A, Koppelman GH, Bustamante M, Levy D, London SJ.

Epigenomics. 2019 Oct;11(13):1487-1500. doi: 10.2217/epi-2019-0066. Epub 2019 Sep 19.

47.

Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health.

Davies NM, Hill WD, Anderson EL, Sanderson E, Deary IJ, Davey Smith G.

Elife. 2019 Sep 17;8. pii: e43990. doi: 10.7554/eLife.43990.

48.

Epigenome-wide association study of leukocyte telomere length.

Lee Y, Sun D, Ori APS, Lu AT, Seeboth A, Harris SE, Deary IJ, Marioni RE, Soerensen M, Mengel-From J, Hjelmborg J, Christensen K, Wilson JG, Levy D, Reiner AP, Chen W, Li S, Harris JR, Magnus P, Aviv A, Jugessur A, Horvath S.

Aging (Albany NY). 2019 Aug 26;11(16):5876-5894. doi: 10.18632/aging.102230. Epub 2019 Aug 26.

49.

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing.

Zhang Q, Vallerga CL, Walker RM, Lin T, Henders AK, Montgomery GW, He J, Fan D, Fowdar J, Kennedy M, Pitcher T, Pearson J, Halliday G, Kwok JB, Hickie I, Lewis S, Anderson T, Silburn PA, Mellick GD, Harris SE, Redmond P, Murray AD, Porteous DJ, Haley CS, Evans KL, McIntosh AM, Yang J, Gratten J, Marioni RE, Wray NR, Deary IJ, McRae AF, Visscher PM.

Genome Med. 2019 Aug 23;11(1):54. doi: 10.1186/s13073-019-0667-1.

50.

Early-life predictors of retirement decisions and post-retirement health.

Iveson MH, Deary IJ.

SSM Popul Health. 2019 Jun 10;8:100430. doi: 10.1016/j.ssmph.2019.100430. eCollection 2019 Aug.

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