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Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans.

Thijssen DHJ, Bruno RM, van Mil ACCM, Holder SM, Faita F, Greyling A, Zock PL, Taddei S, Deanfield JE, Luscher T, Green DJ, Ghiadoni L.

Eur Heart J. 2019 Aug 7;40(30):2534-2547. doi: 10.1093/eurheartj/ehz350.


Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Dangardt F, Charakida M, Georgiopoulos G, Chiesa ST, Rapala A, Wade KH, Hughes AD, Timpson NJ, Pateras K, Finer N, Sattar N, Davey Smith G, Lawlor DA, Deanfield JE.

Lancet Child Adolesc Health. 2019 Jul;3(7):474-481. doi: 10.1016/S2352-4642(19)30105-1. Epub 2019 May 21.


Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study.

Chiesa ST, Masi S, Shipley MJ, Ellins EA, Fraser AG, Hughes AD, Patel RS, Khir AW, Halcox JP, Singh-Manoux A, Kivimaki M, Celermajer DS, Deanfield JE.

Eur Heart J. 2019 Jul 21;40(28):2300-2309. doi: 10.1093/eurheartj/ehz189.


Elevated high-density lipoprotein in adolescents with Type 1 diabetes is associated with endothelial dysfunction in the presence of systemic inflammation.

Chiesa ST, Charakida M, McLoughlin E, Nguyen HC, Georgiopoulos G, Motran L, Elia Y, Marcovecchio ML, Dunger DB, Dalton RN, Daneman D, Sochett E, Mahmud FH, Deanfield JE.

Eur Heart J. 2019 Mar 12. pii: ehz114. doi: 10.1093/eurheartj/ehz114. [Epub ahead of print]


Intensive periodontal therapy and type 2 diabetes - Authors' reply.

D'Aiuto F, Deanfield JE.

Lancet Diabetes Endocrinol. 2019 Mar;7(3):175-176. doi: 10.1016/S2213-8587(19)30030-0. No abstract available.


Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.

Wade KH, Chiesa ST, Hughes AD, Chaturvedi N, Charakida M, Rapala A, Muthurangu V, Khan T, Finer N, Sattar N, Howe LD, Fraser A, Lawlor DA, Davey Smith G, Deanfield JE, Timpson NJ.

Circulation. 2018 Nov 13;138(20):2187-2201. doi: 10.1161/CIRCULATIONAHA.117.033278. Epub 2018 Jul 30.


Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial.

D'Aiuto F, Gkranias N, Bhowruth D, Khan T, Orlandi M, Suvan J, Masi S, Tsakos G, Hurel S, Hingorani AD, Donos N, Deanfield JE; TASTE Group.

Lancet Diabetes Endocrinol. 2018 Dec;6(12):954-965. doi: 10.1016/S2213-8587(18)30038-X. Epub 2018 Oct 24. Erratum in: Lancet Diabetes Endocrinol. 2019 Mar;7(3):e3.


Early vascular damage from smoking and alcohol in teenage years: the ALSPAC study.

Charakida M, Georgiopoulos G, Dangardt F, Chiesa ST, Hughes AD, Rapala A, Davey Smith G, Lawlor D, Finer N, Deanfield JE.

Eur Heart J. 2019 Jan 21;40(4):345-353. doi: 10.1093/eurheartj/ehy524.


BMI trajectories from childhood: the slippery slope to adult obesity and cardiovascular disease.

Charakida M, Deanfield JE.

Eur Heart J. 2018 Jun 21;39(24):2271-2273. doi: 10.1093/eurheartj/ehy218. No abstract available.


Multimorbidity and survival for patients with acute myocardial infarction in England and Wales: Latent class analysis of a nationwide population-based cohort.

Hall M, Dondo TB, Yan AT, Mamas MA, Timmis AD, Deanfield JE, Jernberg T, Hemingway H, Fox KAA, Gale CP.

PLoS Med. 2018 Mar 6;15(3):e1002501. doi: 10.1371/journal.pmed.1002501. eCollection 2018 Mar.


The Congenital Heart Disease Genetic Network Study: Cohort description.

Hoang TT, Goldmuntz E, Roberts AE, Chung WK, Kline JK, Deanfield JE, Giardini A, Aleman A, Gelb BD, Mac Neal M, Porter GA Jr, Kim R, Brueckner M, Lifton RP, Edman S, Woyciechowski S, Mitchell LE, Agopian AJ.

PLoS One. 2018 Jan 19;13(1):e0191319. doi: 10.1371/journal.pone.0191319. eCollection 2018.


Management errors in adults with congenital heart disease: prevalence, sources, and consequences.

Cordina R, Nasir Ahmad S, Kotchetkova I, Eveborn G, Pressley L, Ayer J, Chard R, Tanous D, Robinson P, Kilian J, Deanfield JE, Celermajer DS.

Eur Heart J. 2018 Mar 21;39(12):982-989. doi: 10.1093/eurheartj/ehx685.


Relative Survival After Transcatheter Aortic Valve Implantation: How Do Patients Undergoing Transcatheter Aortic Valve Implantation Fare Relative to the General Population?

Martin GP, Sperrin M, Hulme W, Ludman PF, de Belder MA, Toff WD, Alabas O, Moat NE, Doshi SN, Buchan I, Deanfield JE, Gale CP, Mamas MA; National Institute of Cardiovascular Outcomes Research (NICOR).

J Am Heart Assoc. 2017 Oct 17;6(10). pii: e007229. doi: 10.1161/JAHA.117.007229.


β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction.

Dondo TB, Hall M, West RM, Jernberg T, Lindahl B, Bueno H, Danchin N, Deanfield JE, Hemingway H, Fox KAA, Timmis AD, Gale CP.

J Am Coll Cardiol. 2017 Jun 6;69(22):2710-2720. doi: 10.1016/j.jacc.2017.03.578.


Increased fibrinogen responses to psychophysiological stress predict future endothelial dysfunction implications for cardiovascular disease?

Ellins EA, Rees DA, Deanfield JE, Steptoe A, Halcox JP.

Brain Behav Immun. 2017 Feb;60:233-239. doi: 10.1016/j.bbi.2016.10.017. Epub 2016 Oct 18.


Online self-assessment of cardiovascular risk using the Joint British Societies (JBS3)-derived heart age tool: a descriptive study.

Patel RS, Lagord C, Waterall J, Moth M, Knapton M, Deanfield JE.

BMJ Open. 2016 Sep 28;6(9):e011511. doi: 10.1136/bmjopen-2016-011511.


Association of Clinical Factors and Therapeutic Strategies With Improvements in Survival Following Non-ST-Elevation Myocardial Infarction, 2003-2013.

Hall M, Dondo TB, Yan AT, Goodman SG, Bueno H, Chew DP, Brieger D, Timmis A, Batin PD, Deanfield JE, Hemingway H, Fox KA, Gale CP.

JAMA. 2016 Sep 13;316(10):1073-82. doi: 10.1001/jama.2016.10766.


Geographic variation in the treatment of non-ST-segment myocardial infarction in the English National Health Service: a cohort study.

Dondo TB, Hall M, Timmis AD, Yan AT, Batin PD, Oliver G, Alabas OA, Norman P, Deanfield JE, Bloor K, Hemingway H, Gale CP.

BMJ Open. 2016 Jul 12;6(7):e011600. doi: 10.1136/bmjopen-2016-011600.


Long-term excess mortality associated with diabetes following acute myocardial infarction: a population-based cohort study.

Alabas OA, Hall M, Dondo TB, Rutherford MJ, Timmis AD, Batin PD, Deanfield JE, Hemingway H, Gale CP.

J Epidemiol Community Health. 2017 Jan;71(1):25-32. doi: 10.1136/jech-2016-207402. Epub 2016 Jun 15.


Telomere length, antioxidant status and incidence of ischaemic heart disease in type 2 diabetes.

Masi S, D'Aiuto F, Cooper J, Salpea K, Stephens JW, Hurel SJ, Deanfield JE, Humphries SE.

Int J Cardiol. 2016 Aug 1;216:159-64. doi: 10.1016/j.ijcard.2016.04.130. Epub 2016 Apr 22.


Excess mortality and guideline-indicated care following non-ST-elevation myocardial infarction.

Dondo TB, Hall M, Timmis AD, Gilthorpe MS, Alabas OA, Batin PD, Deanfield JE, Hemingway H, Gale CP.

Eur Heart J Acute Cardiovasc Care. 2017 Aug;6(5):412-420. doi: 10.1177/2048872616647705. Epub 2016 May 3.


Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.

Boardman-Pretty F, Smith AJ, Cooper J, Palmen J, Folkersen L, Hamsten A, Catapano AL, Melander O, Price JF, Kumari M, Deanfield JE, Kivimäki M, Gertow K, Baragetti A, Norata GD, Humphries SE.

Circ Cardiovasc Genet. 2015 Oct;8(5):696-706. doi: 10.1161/CIRCGENETICS.115.001062. Epub 2015 Aug 14.


Lifetime risk: childhood obesity and cardiovascular risk.

Ayer J, Charakida M, Deanfield JE, Celermajer DS.

Eur Heart J. 2015 Jun 7;36(22):1371-6. doi: 10.1093/eurheartj/ehv089. Epub 2015 Mar 24. Review.


Novel coronary heart disease risk factors at 60-64 years and life course socioeconomic position: the 1946 British birth cohort.

Jones R, Hardy R, Sattar N, Deanfield JE, Hughes A, Kuh D, Murray ET, Whincup PH, Thomas C; NSHD Scientific and Data Collection Teams.

Atherosclerosis. 2015 Jan;238(1):70-6. doi: 10.1016/j.atherosclerosis.2014.11.011. Epub 2014 Nov 18.


Haemodynamic consequences of targeted single- and dual-site right ventricular pacing in adults with congenital heart disease undergoing surgical pulmonary valve replacement.

Plymen CM, Finlay M, Tsang V, O'leary J, Picaut N, Cullen S, Walker F, Deanfield JE, Hsia TY, Bolger AP, Lambiase PD.

Europace. 2015 Feb;17(2):274-80. doi: 10.1093/europace/euu281. Epub 2014 Nov 4.


Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort.

Masi S, D'Aiuto F, Martin-Ruiz C, Kahn T, Wong A, Ghosh AK, Whincup P, Kuh D, Hughes A, von Zglinicki T, Hardy R, Deanfield JE; NSHD scientific and data collection teams.

Eur Heart J. 2014 Dec 7;35(46):3296-303. doi: 10.1093/eurheartj/ehu226. Epub 2014 Jun 22.


Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.

Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H.

Lancet. 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1.


HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype.

Shroff R, Speer T, Colin S, Charakida M, Zewinger S, Staels B, Chinetti-Gbaguidi G, Hettrich I, Rohrer L, O'Neill F, McLoughlin E, Long D, Shanahan CM, Landmesser U, Fliser D, Deanfield JE.

J Am Soc Nephrol. 2014 Nov;25(11):2658-68. doi: 10.1681/ASN.2013111212. Epub 2014 May 22.


Association between resting heart rate across the life course and all-cause mortality: longitudinal findings from the Medical Research Council (MRC) National Survey of Health and Development (NSHD).

Ó Hartaigh B, Gill TM, Shah I, Hughes AD, Deanfield JE, Kuh D, Hardy R.

J Epidemiol Community Health. 2014 Sep;68(9):883-9. doi: 10.1136/jech-2014-203940. Epub 2014 May 21.


Association between short leukocyte telomere length, endotoxemia, and severe periodontitis in people with diabetes: a cross-sectional survey.

Masi S, Gkranias N, Li K, Salpea KD, Parkar M, Orlandi M, Suvan JE, Eng HL, Taddei S, Patel K, Darbar U, Donos N, Deanfield JE, Hurel S, Humphries SE, D'Aiuto F.

Diabetes Care. 2014 Apr;37(4):1140-7. doi: 10.2337/dc13-2106.


Association between components of body composition and scoliosis: a prospective cohort study reporting differences identifiable before the onset of scoliosis.

Clark EM, Taylor HJ, Harding I, Hutchinson J, Nelson I, Deanfield JE, Ness AR, Tobias JH.

J Bone Miner Res. 2014 Aug;29(8):1729-36. doi: 10.1002/jbmr.2207.


Body mass index and height from infancy to adulthood and carotid intima-media thickness at 60 to 64 years in the 1946 British Birth Cohort Study.

Johnson W, Kuh D, Tikhonoff V, Charakida M, Woodside J, Whincup P, Hughes AD, Deanfield JE, Hardy R; NSHD Scientific and Data Collection Teams.

Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):654-60. doi: 10.1161/ATVBAHA.113.302572. Epub 2014 Jan 23.


Reply: Intestinal cholesterol absorption and cardiovascular risk.

Silbernagel G, Chapman MJ, Genser B, Kleber ME, Fauler G, Scharnagl H, Grammer TB, Mäkelä KM, Kähönen M, Carmena R, Rietzschel ER, Bruckert E, Deanfield JE, Raitakari OT, Lehtimäki T, März W.

J Am Coll Cardiol. 2014 Feb 25;63(7):696-697. doi: 10.1016/j.jacc.2013.09.081. Epub 2013 Dec 11. No abstract available.


An assessment of composite measures of hospital performance and associated mortality for patients with acute myocardial infarction. Analysis of individual hospital performance and outcome for the National Institute for Cardiovascular Outcomes Research (NICOR).

Simms AD, Baxter PD, Cattle BA, Batin PD, Wilson JI, West RM, Hall AS, Weston CF, Deanfield JE, Fox KA, Gale CP.

Eur Heart J Acute Cardiovasc Care. 2013 Mar;2(1):9-18. doi: 10.1177/2048872612469132.


Nighttime aircraft noise exposure: flying towards arterial disease.

Charakida M, Deanfield JE.

Eur Heart J. 2013 Dec;34(45):3472-4. doi: 10.1093/eurheartj/eht339. Epub 2013 Aug 28. No abstract available.


Variability and reproducibility of flow-mediated dilatation in a multicentre clinical trial.

Charakida M, de Groot E, Loukogeorgakis SP, Khan T, Lüscher T, Kastelein JJ, Gasser T, Deanfield JE.

Eur Heart J. 2013 Dec;34(45):3501-7. doi: 10.1093/eurheartj/eht223. Epub 2013 Jul 2.


Exercise: friend or foe?

Dangardt FJ, McKenna WJ, Lüscher TF, Deanfield JE.

Nat Rev Cardiol. 2013 Sep;10(9):495-507. doi: 10.1038/nrcardio.2013.90. Epub 2013 Jun 25. Review.


High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis.

Silbernagel G, Chapman MJ, Genser B, Kleber ME, Fauler G, Scharnagl H, Grammer TB, Boehm BO, Mäkelä KM, Kähönen M, Carmena R, Rietzschel ER, Bruckert E, Deanfield JE, Miettinen TA, Raitakari OT, Lehtimäki T, März W.

J Am Coll Cardiol. 2013 Jul 23;62(4):291-9. doi: 10.1016/j.jacc.2013.01.100. Epub 2013 May 22.


Habitual alcohol consumption is associated with lower cardiovascular stress responses--a novel explanation for the known cardiovascular benefits of alcohol?

Jones A, McMillan MR, Jones RW, Kowalik GT, Steeden JA, Pruessner JC, Taylor AM, Deanfield JE, Muthurangu V.

Stress. 2013 Jul;16(4):369-76. doi: 10.3109/10253890.2013.777833. Epub 2013 Apr 8.


The Year in Cardiology 2012: focus on cardiovascular disease prevention.

Charakida M, Masi S, Deanfield JE.

Eur Heart J. 2013 Jan;34(4):314-7. doi: 10.1093/eurheartj/ehs429. Epub 2013 Jan 2. Review.


High-dose statin monotherapy versus low-dose statin/ezetimibe combination on fasting and postprandial lipids and endothelial function in obese patients with the metabolic syndrome: The PANACEA study.

Westerink J, Deanfield JE, Imholz BP, Spiering W, Basart DC, Coll B, Kastelein JJ, Visseren FL.

Atherosclerosis. 2013 Mar;227(1):118-24. doi: 10.1016/j.atherosclerosis.2012.11.028. Epub 2012 Dec 6.


A gene-centric study of common carotid artery remodelling.

Harrison SC, Zabaneh D, Asselbergs FW, Drenos F, Jones GT, Shah S, Gertow K, Sennblad B, Strawbridge RJ, Gigante B, Holewijn S, De Graaf J, Vermeulen S, Folkersen L, van Rij AM, Baldassarre D, Veglia F, Talmud PJ, Deanfield JE, Agu O, Kivimaki M, Kumari M, Bown MJ, Nyyssönen K, Rauramaa R, Smit AJ, Franco-Cereceda A, Giral P, Mannarino E, Silveira A, Syvänen AC, de Borst GJ, van der Graaf Y, de Faire U, Baas AF, Blankensteijn JD, Wareham NJ, Fowkes G, Tzoulaki I, Price JF, Tremoli E, Hingorani AD, Eriksson P, Hamsten A, Humphries SE.

Atherosclerosis. 2013 Feb;226(2):440-6. doi: 10.1016/j.atherosclerosis.2012.11.002. Epub 2012 Nov 23.


Childhood obesity and vascular phenotypes: a population study.

Charakida M, Jones A, Falaschetti E, Khan T, Finer N, Sattar N, Hingorani A, Lawlor DA, Smith GD, Deanfield JE.

J Am Coll Cardiol. 2012 Dec 25;60(25):2643-50. doi: 10.1016/j.jacc.2012.08.1017. Epub 2012 Nov 21.


Evaluation of the NICE mini-GRACE risk scores for acute myocardial infarction using the Myocardial Ischaemia National Audit Project (MINAP) 2003-2009: National Institute for Cardiovascular Outcomes Research (NICOR).

Simms AD, Reynolds S, Pieper K, Baxter PD, Cattle BA, Batin PD, Wilson JI, Deanfield JE, West RM, Fox KA, Hall AS, Gale CP.

Heart. 2013 Jan;99(1):35-40. doi: 10.1136/heartjnl-2012-302632. Epub 2012 Sep 22.


Impact of pulmonary valve replacement in tetralogy of Fallot with pulmonary regurgitation: a comparison of intervention and nonintervention.

Quail MA, Frigiola A, Giardini A, Muthurangu V, Hughes M, Lurz P, Khambadkone S, Deanfield JE, Tsang V, Taylor AM.

Ann Thorac Surg. 2012 Nov;94(5):1619-26. doi: 10.1016/j.athoracsur.2012.06.062. Epub 2012 Sep 7.


Cardiac outcomes in adults with supravalvar aortic stenosis.

Greutmann M, Tobler D, Sharma NC, Vonder Muhll I, Mebus S, Kaemmerer H, Schuler PK, Deanfield JE, Beauchesne L, Salehian O, Hoffmann A, Golovatyuk V, Oechslin EN, Silversides CK.

Eur Heart J. 2012 Oct;33(19):2442-50. doi: 10.1093/eurheartj/ehs206. Epub 2012 Jul 19.


Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia.

Fabbri-Arrigoni FI, Clarke L, Wang G, Charakida M, Ellins E, Halliday N, Brogan PA, Deanfield JE, Halcox JP, Klein N.

Pediatr Res. 2012 Sep;72(3):299-304. doi: 10.1038/pr.2012.76. Epub 2012 Jun 12.


Adiposity is associated with blunted cardiovascular, neuroendocrine and cognitive responses to acute mental stress.

Jones A, McMillan MR, Jones RW, Kowalik GT, Steeden JA, Deanfield JE, Pruessner JC, Taylor AM, Muthurangu V.

PLoS One. 2012;7(6):e39143. doi: 10.1371/journal.pone.0039143. Epub 2012 Jun 20.


Engaging with the clinical data transparency initiative: a view from the National Institute for Cardiovascular Outcomes Research (NICOR).

Gale CP, Weston C, Denaxas S, Cunningham D, de Belder MA, Gray HH, Boyle R, Deanfield JE; NICOR Executive.

Heart. 2012 Jul;98(14):1040-3. doi: 10.1136/heartjnl-2012-302469. No abstract available.


Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents.

Masi S, Nightingale CM, Day IN, Guthrie P, Rumley A, Lowe GD, von Zglinicki T, D'Aiuto F, Taddei S, Klein N, Salpea K, Cook DG, Humphries SE, Whincup PH, Deanfield JE.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):2029-34. doi: 10.1161/ATVBAHA.112.250589. Epub 2012 Jun 7.


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