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Items: 1 to 50 of 105

1.

Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment: A Randomized Clinical Trial.

Chandler MJ, Locke DE, Crook JE, Fields JA, Ball CT, Phatak VS, Dean PM, Morris M, Smith GE.

JAMA Netw Open. 2019 May 3;2(5):e193016. doi: 10.1001/jamanetworkopen.2019.3016.

2.

Self-Efficacy Mediates the Association Between Physical Function and Perceived Quality of Life in Individuals with Mild Cognitive Impairment.

Langer K, O'Shea DM, De Wit L, DeFeis B, Mejia A, Amofa P, Chandler M, Locke DEC, Fields J, Phatak V, Dean PM, Smith G.

J Alzheimers Dis. 2019;68(4):1511-1519. doi: 10.3233/JAD-181020.

PMID:
30909227
3.

Deciding to adopt revised and new psychological and neuropsychological tests: an inter-organizational position paper.

Bush SS, Sweet JJ, Bianchini KJ, Johnson-Greene D, Dean PM, Schoenberg MR.

Clin Neuropsychol. 2018 Apr;32(3):319-325. doi: 10.1080/13854046.2017.1422277. Epub 2018 Jan 18.

PMID:
29345214
4.

Correction for a potentially biased item on the Mattis dementia rating scale.

Dean PM, Cerhan JH.

Am J Alzheimers Dis Other Demen. 2013 Dec;28(8):734-7. doi: 10.1177/1533317513504610. Epub 2013 Oct 1.

PMID:
24085248
5.

Neurocognitive speed associates with frontotemporal lobar degeneration TDP-43 subtypes.

Dean PM, Smith GE, Parisi JE, Dickson DW, Petersen RC, Josephs KA.

J Clin Neurosci. 2013 Dec;20(12):1737-41. doi: 10.1016/j.jocn.2013.01.024. Epub 2013 Sep 4.

6.

Identification of an atypical variant of logopenic progressive aphasia.

Machulda MM, Whitwell JL, Duffy JR, Strand EA, Dean PM, Senjem ML, Jack CR Jr, Josephs KA.

Brain Lang. 2013 Nov;127(2):139-44. doi: 10.1016/j.bandl.2013.02.007. Epub 2013 Apr 6.

7.

Protic pharmaceutical ionic liquids and solids: aspects of protonics.

Stoimenovski J, Dean PM, Izgorodina EI, MacFarlane DR.

Faraday Discuss. 2012;154:335-52; discussion 439-64, 465-71.

PMID:
22455028
8.

Understanding the effect of the C2 proton in promoting low viscosities and high conductivities in imidazolium-based ionic liquids: part I. Weakly coordinating anions.

Izgorodina EI, Maganti R, Armel V, Dean PM, Pringle JM, Seddon KR, MacFarlane DR.

J Phys Chem B. 2011 Dec 15;115(49):14688-97. doi: 10.1021/jp208573y. Epub 2011 Nov 14.

PMID:
22023104
9.

Structural analysis of low melting organic salts: perspectives on ionic liquids.

Dean PM, Pringle JM, MacFarlane DR.

Phys Chem Chem Phys. 2010 Aug 28;12(32):9144-53. doi: 10.1039/c003519j. Epub 2010 Jun 30.

PMID:
20593067
10.
11.

Clinical evaluation of the mini-mental state exam with culturally deaf senior citizens.

Dean PM, Feldman DM, Morere D, Morton D.

Arch Clin Neuropsychol. 2009 Dec;24(8):753-60. doi: 10.1093/arclin/acp077. Epub 2009 Oct 27.

PMID:
19861331
12.

Methyl 9H-xanthene-9-carboxyl-ate.

Dean PM, Turanjanin J, Macfarlane DR.

Acta Crystallogr Sect E Struct Rep Online. 2008 Apr 16;64(Pt 5):o854. doi: 10.1107/S1600536808005990.

13.

1-Methyl-1-propyl-pyrrolidinium chloride.

Dean PM, Pringle JM, Macfarlane DR.

Acta Crystallogr Sect E Struct Rep Online. 2008 Feb 29;64(Pt 3):o637. doi: 10.1107/S1600536808005229.

14.

Chemical genomics: a challenge for de novo drug design.

Dean PM.

Mol Biotechnol. 2007 Nov;37(3):237-45. Epub 2007 Jun 30. Review.

PMID:
17952670
15.

QUASI: a novel method for simultaneous superposition of multiple flexible ligands and virtual screening using partial similarity.

Todorov NP, Alberts IL, de Esch IJ, Dean PM.

J Chem Inf Model. 2007 May-Jun;47(3):1007-20. Epub 2007 May 12.

PMID:
17497844
16.

Sodium pyridine-3-carboxylate.

Forsyth CM, Dean PM, MacFarlane DR.

Acta Crystallogr C. 2007 Apr;63(Pt 4):m169-70. Epub 2007 Mar 31.

PMID:
17413224
17.

SkelGen: a general tool for structure-based de novo ligand design.

Dean PM, Firth-Clark S, Harris W, Kirton SB, Todorov NP.

Expert Opin Drug Discov. 2006 Jul;1(2):179-89. doi: 10.1517/17460441.1.2.179.

PMID:
23495800
18.

Exhaustive de novo design of low-molecular-weight fragments against the ATP-binding site of DNA-gyrase.

Firth-Clark S, Todorov NP, Alberts IL, Williams A, James T, Dean PM.

J Chem Inf Model. 2006 May-Jun;46(3):1168-73.

PMID:
16711736
19.

The impact of epilepsy surgery on quality of life in children.

Sabaz M, Lawson JA, Cairns DR, Duchowny MS, Resnick TJ, Dean PM, Bleasel AF, Bye AM.

Neurology. 2006 Feb 28;66(4):557-61.

PMID:
16505311
20.

Computer-aided design of small molecules for chemical genomics.

Dean PM.

Methods Mol Biol. 2005;310:25-39.

PMID:
16350945
21.

Receptor flexibility in de novo ligand design and docking.

Alberts IL, Todorov NP, Dean PM.

J Med Chem. 2005 Oct 20;48(21):6585-96.

PMID:
16220975
22.

New crystalline forms of permethylated beta-cyclodextrin.

Caira MR, Bourne SA, Mhlongo WT, Dean PM.

Chem Commun (Camb). 2004 Oct 7;(19):2216-7. Epub 2004 Aug 20.

PMID:
15467879
23.

Backbone-backbone geometry of tertiary contacts between alpha-helices.

Källblad P, Dean PM.

Proteins. 2004 Sep 1;56(4):693-703.

PMID:
15281123
24.

De novo drug design: integration of structure-based and ligand-based methods.

Dean PM, Lloyd DG, Todorov NP.

Curr Opin Drug Discov Devel. 2004 May;7(3):347-53. Review.

PMID:
15216939
25.

Scaffold hopping in de novo design. Ligand generation in the absence of receptor information.

Lloyd DG, Buenemann CL, Todorov NP, Manallack DT, Dean PM.

J Med Chem. 2004 Jan 29;47(3):493-6.

PMID:
14736231
26.

Validation of the quality of life in childhood epilepsy questionnaire in American epilepsy patients.

Sabaz M, Lawson JA, Cairns DR, Duchowny MS, Resnick TJ, Dean PM, Bye AM.

Epilepsy Behav. 2003 Dec;4(6):680-91.

PMID:
14698702
27.
28.

Efficient conformational sampling of local side-chain flexibility.

Källblad P, Dean PM.

J Mol Biol. 2003 Mar 7;326(5):1651-65.

PMID:
12595271
29.

A validation study on the practical use of automated de novo design.

Stahl M, Todorov NP, James T, Mauser H, Boehm HJ, Dean PM.

J Comput Aided Mol Des. 2002 Jul;16(7):459-78.

PMID:
12510880
30.

Probes for chemical genomics by design.

Zanders ED, Bailey DS, Dean PM.

Drug Discov Today. 2002 Jul 1;7(13):711-8. Review.

PMID:
12110227
31.

The use of chemical design tools to transform proteomics data into drug candidates.

Dean PM, Zanders ED.

Biotechniques. 2002 Mar;Suppl:28-33. Review.

PMID:
11906004
32.

Industrial-scale, genomics-based drug design and discovery.

Dean PM, Zanders ED, Bailey DS.

Trends Biotechnol. 2001 Aug;19(8):288-92.

PMID:
11451470
33.

Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.

De Esch IJ, Mills JE, Perkins TD, Romeo G, Hoffmann M, Wieland K, Leurs R, Menge WM, Nederkoorn PH, Dean PM, Timmerman H.

J Med Chem. 2001 May 24;44(11):1666-74.

PMID:
11356102
34.

SLATE: a method for the superposition of flexible ligands.

Mills JE, de Esch IJ, Perkins TD, Dean PM.

J Comput Aided Mol Des. 2001 Jan;15(1):81-96.

PMID:
11217921
35.

Recent advances in structure-based rational drug design.

Gane PJ, Dean PM.

Curr Opin Struct Biol. 2000 Aug;10(4):401-4. Review.

PMID:
10981625
36.

Design criteria for molecular mimics of fragments of the beta-turn. 2. C alpha-C beta bond vector analysis.

Garland SL, Dean PM.

J Comput Aided Mol Des. 1999 Sep;13(5):485-98.

PMID:
10483530
37.

Design criteria for molecular mimics of fragments of the beta-turn. 1. C alpha atom analysis.

Garland SL, Dean PM.

J Comput Aided Mol Des. 1999 Sep;13(5):469-83.

PMID:
10483529
38.

A branch-and-bound method for optimal atom-type assignment in de novo ligand design.

Todorov NP, Dean PM.

J Comput Aided Mol Des. 1998 Jul;12(4):335-49.

PMID:
9777492
39.

An automated method for predicting the positions of hydrogen-bonding atoms in binding sites.

Mills JE, Perkins TD, Dean PM.

J Comput Aided Mol Des. 1997 May;11(3):229-42.

PMID:
9263850
40.

Evaluation of a method for controlling molecular scaffold diversity in de novo ligand design.

Todorov NP, Dean PM.

J Comput Aided Mol Des. 1997 Mar;11(2):175-92.

PMID:
9089435
41.

Three-dimensional hydrogen-bond geometry and probability information from a crystal survey.

Mills JE, Dean PM.

J Comput Aided Mol Des. 1996 Dec;10(6):607-22.

PMID:
9007693
42.
43.

Hydration in drug design. 2. Influence of local site surface shape on water binding.

Poornima CS, Dean PM.

J Comput Aided Mol Des. 1995 Dec;9(6):513-20.

PMID:
8789193
44.
45.

Molecular surface-volume and property matching to superpose flexible dissimilar molecules.

Perkins TD, Mills JE, Dean PM.

J Comput Aided Mol Des. 1995 Dec;9(6):479-90.

PMID:
8789190
49.
50.

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