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Items: 1 to 50 of 1679

1.

Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.

Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.

Crit Care Med. 2020 Mar;48(3):329-337. doi: 10.1097/CCM.0000000000004123.

PMID:
32058370
2.

Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.

Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators.

Crit Care Med. 2020 Mar;48(3):319-328. doi: 10.1097/CCM.0000000000004122.

PMID:
32058369
3.

Innate inflammation drives NK cell activation to impair Treg activity.

Dean JW, Peters LD, Fuhrman CA, Seay HR, Posgai AL, Stimpson SE, Brusko MA, Perry DJ, Yeh WI, Newby BN, Haller MJ, Muir AB, Atkinson MA, Mathews CE, Brusko TM.

J Autoimmun. 2020 Feb 5:102417. doi: 10.1016/j.jaut.2020.102417. [Epub ahead of print]

PMID:
32035746
4.

The influence of lateral stabilization on walking performance and balance control in neurologically-intact and post-stroke individuals.

Frame HB, Finetto C, Dean JC, Neptune RR.

Clin Biomech (Bristol, Avon). 2020 Jan 28;73:172-180. doi: 10.1016/j.clinbiomech.2020.01.005. [Epub ahead of print]

PMID:
32004909
5.

Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism.

Gunning AC, Strucinska K, Muñoz Oreja M, Parrish A, Caswell R, Stals KL, Durigon R, Durlacher-Betzer K, Cunningham MH, Grochowski CM, Baptista J, Tysoe C, Baple E, Lahiri N, Homfray T, Scurr I, Armstrong C, Dean J, Fernandez Pelayo U, Jones AWE, Taylor RW, Misra VK, Yoon WH, Wright CF, Lupski JR, Spinazzola A, Harel T, Holt IJ, Ellard S.

Am J Hum Genet. 2020 Feb 6;106(2):272-279. doi: 10.1016/j.ajhg.2020.01.007. Epub 2020 Jan 30.

6.

Customization scenarios for de-identification of clinical notes.

Hartman T, Howell MD, Dean J, Hoory S, Slyper R, Laish I, Gilon O, Vainstein D, Corrado G, Chou K, Po MJ, Williams J, Ellis S, Bee G, Hassidim A, Amira R, Beryozkin G, Szpektor I, Matias Y.

BMC Med Inform Decis Mak. 2020 Jan 30;20(1):14. doi: 10.1186/s12911-020-1026-2.

7.

Working hours, common mental disorder and suicidal ideation among junior doctors in Australia: a cross-sectional survey.

Petrie K, Crawford J, LaMontagne AD, Milner A, Dean J, Veness BG, Christensen H, Harvey SB.

BMJ Open. 2020 Jan 21;10(1):e033525. doi: 10.1136/bmjopen-2019-033525.

8.

Reduced sensitivity from pooled urine, pharyngeal and rectal specimens when using a molecular assay for the detection of chlamydia and gonorrhoea near the point of care.

Badman SG, Bell SFE, Dean JA, Lemoire J, Coffey L, Debattista J, Redmond AM, Williams OD, Gilks CF, Whiley DM.

Sex Health. 2020 Jan 17. doi: 10.1071/SH19028. [Epub ahead of print]

PMID:
31945307
9.

VTE prophylaxis for medical patients when they leave hospital: a wider approach to future research and evidence is required.

Dean J.

Clin Med (Lond). 2020 Jan;20(1):119. doi: 10.7861/clinmedicine.20-1-119. No abstract available.

10.

TLR7 agonist modulation of postasphyxial neurophysiological and cardiovascular adaptations in preterm fetal sheep.

Cho KHT, Fraser M, Wassink G, Dhillon SJ, Davidson JO, Dean JM, Gunn AJ, Bennet L.

Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R369-R378. doi: 10.1152/ajpregu.00295.2019. Epub 2020 Jan 8.

PMID:
31913689
11.

Structured Chart Review: Assessment of a Structured Chart Review Methodology.

Siems A, Banks R, Holubkov R, Meert KL, Bauerfeld C, Beyda D, Berg RA, Bulut Y, Burd RS, Carcillo J, Dean JM, Gradidge E, Hall MW, McQuillen PS, Mourani PM, Newth CJL, Notterman DA, Priestley MA, Sapru A, Wessel DL, Yates AR, Zuppa AF, Pollack MM.

Hosp Pediatr. 2020 Jan;10(1):61-69. doi: 10.1542/hpeds.2019-0225.

PMID:
31879317
12.

Relative Selectivity of Covalent Inhibitors Requires Assessment of Inactivation Kinetics and Cellular Occupancy: A Case Study of Ibrutinib and Acalabrutinib.

Hopper M, Gururaja T, Kinoshita T, Dean JP, Hill RJ, Mongan A.

J Pharmacol Exp Ther. 2019 Dec 23. pii: jpet.119.262063. doi: 10.1124/jpet.119.262063. [Epub ahead of print]

13.

Simultaneous osteosarcoma and renal cell carcinoma with BRCA1 mutation in a young male adult with prior oligodendroglioma.

Dhir A, Li R, Li G, Dean J, Robin NH, Alva E.

Pediatr Blood Cancer. 2020 Mar;67(3):e28116. doi: 10.1002/pbc.28116. Epub 2019 Dec 18. No abstract available.

PMID:
31850619
14.

Developing a Preliminary Conceptual Framework for Guidelines on Inclusion of Patient Reported-Outcome Measures (PROMs) in Clinical Quality Registries.

Ruseckaite R, Maharaj AD, Krysinska K, Dean J, Ahern S.

Patient Relat Outcome Meas. 2019 Dec 10;10:355-372. doi: 10.2147/PROM.S229569. eCollection 2019.

15.

FEV1 recovery following methacholine challenge in asthma: Variability and comparison of methods.

Singh D, Khan N, Dean J, Fowler A, Gupta A, Endriss V, Iacono P, Disse B.

Pulm Pharmacol Ther. 2020 Feb;60:101876. doi: 10.1016/j.pupt.2019.101876. Epub 2019 Dec 13.

16.

Altered post-stroke propulsion is related to paretic swing phase kinematics.

Dean JC, Bowden MG, Kelly AL, Kautz SA.

Clin Biomech (Bristol, Avon). 2019 Nov 29;72:24-30. doi: 10.1016/j.clinbiomech.2019.11.024. [Epub ahead of print]

PMID:
31809919
17.

Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.

Flores C, Wildes T, Dean BD, Moore G, Drake J, Abraham R, Gil J, Yegorov O, Yang C, Dean J, Moneypenny C, Shin D, Pham C, Krauser J, King J, Grant G, Driscoll T, Kurtzberg J, McLendon R, Gururangan S, Mitchell D.

Sci Adv. 2019 Nov 27;5(11):eaav9879. doi: 10.1126/sciadv.aav9879. eCollection 2019 Nov.

18.

Level of Consciousness Is Dissociable from Electroencephalographic Measures of Cortical Connectivity, Slow Oscillations, and Complexity.

Pal D, Li D, Dean JG, Brito MA, Liu T, Fryzel AM, Hudetz AG, Mashour GA.

J Neurosci. 2020 Jan 15;40(3):605-618. doi: 10.1523/JNEUROSCI.1910-19.2019. Epub 2019 Nov 27.

PMID:
31776211
19.

A randomised assessment of image guided radiotherapy within a phase 3 trial of conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer.

Murray J, Griffin C, Gulliford S, Syndikus I, Staffurth J, Panades M, Scrase C, Parker C, Khoo V, Dean J, Mayles H, Mayles P, Thomas S, Naismith O, Baker A, Mossop H, Cruickshank C, Hall E, Dearnaley D; CHHiP Investigators.

Radiother Oncol. 2020 Jan;142:62-71. doi: 10.1016/j.radonc.2019.10.017. Epub 2019 Nov 22.

20.

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

Wang Z, Xu X, Li JL, Palmer C, Maric D, Dean J.

Nat Commun. 2019 Nov 15;10(1):5196. doi: 10.1038/s41467-019-13193-3.

21.

The CHD8 overgrowth syndrome: A detailed evaluation of an emerging overgrowth phenotype in 27 patients.

Ostrowski PJ, Zachariou A, Loveday C, Beleza-Meireles A, Bertoli M, Dean J, Douglas AGL, Ellis I, Foster A, Graham JM, Hague J, Hilhorst-Hofstee Y, Hoffer M, Johnson D, Josifova D, Kant SG, Kini U, Lachlan K, Lam W, Lees M, Lynch S, Maitz S, McKee S, Metcalfe K, Nathanson K, Ockeloen CW, Parker MJ, Pierson TM, Rahikkala E, Sanchez-Lara PA, Spano A, Van Maldergem L, Cole T, Douzgou S, Tatton-Brown K.

Am J Med Genet C Semin Med Genet. 2019 Dec;181(4):557-564. doi: 10.1002/ajmg.c.31749. Epub 2019 Nov 13.

PMID:
31721432
22.

Update from RCP Quality Improvement: Bringing together the experts to improve services.

Dean J, Gentles H, Burling L.

Future Healthc J. 2019 Oct;6(3):154-155. doi: 10.7861/fhj.QI-6-3. No abstract available.

23.

Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study.

Burger JA, Barr PM, Robak T, Owen C, Ghia P, Tedeschi A, Bairey O, Hillmen P, Coutre SE, Devereux S, Grosicki S, McCarthy H, Simpson D, Offner F, Moreno C, Dai S, Lal I, Dean JP, Kipps TJ.

Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0602-x. [Epub ahead of print]

PMID:
31628428
24.

A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure.

Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Pediatr Crit Care Med. 2019 Dec;20(12):1137-1146. doi: 10.1097/PCC.0000000000002105.

PMID:
31568246
25.

Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation.

Cashen K, Dalton H, Reeder RW, Saini A, Zuppa AF, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Pediatr Crit Care Med. 2020 Feb;21(2):178-185. doi: 10.1097/PCC.0000000000002102.

PMID:
31568245
26.

Unfolding adsorption on metal nanoparticles: Connecting stability with catalysis.

Dean J, Taylor MG, Mpourmpakis G.

Sci Adv. 2019 Sep 13;5(9):eaax5101. doi: 10.1126/sciadv.aax5101. eCollection 2019 Sep.

27.

Application of a Novel Force-Field to Manipulate the Relationship Between Pelvis Motion and Step Width in Human Walking.

Heitkamp LN, Stimpson KH, Dean JC.

IEEE Trans Neural Syst Rehabil Eng. 2019 Oct;27(10):2051-2058. doi: 10.1109/TNSRE.2019.2941372. Epub 2019 Sep 19.

PMID:
31545734
28.

Final analysis from RESONATE: Up to six years of follow-up on ibrutinib in patients with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma.

Munir T, Brown JR, O'Brien S, Barrientos JC, Barr PM, Reddy NM, Coutre S, Tam CS, Mulligan SP, Jaeger U, Kipps TJ, Moreno C, Montillo M, Burger JA, Byrd JC, Hillmen P, Dai S, Szoke A, Dean JP, Woyach JA.

Am J Hematol. 2019 Dec;94(12):1353-1363. doi: 10.1002/ajh.25638. Epub 2019 Oct 13.

29.

Holding the keys to health? A scoping study of the population health impacts of automated vehicles.

Dean J, Wray AJ, Braun L, Casello JM, McCallum L, Gower S.

BMC Public Health. 2019 Sep 11;19(1):1258. doi: 10.1186/s12889-019-7580-9. Review.

30.

A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination.

Su W, Matsumoto S, Banine F, Srivastava T, Dean J, Foster S, Pham P, Hammond B, Peters A, Girish KS, Rangappa KS, Basappa, Jose J, Hennebold JD, Murphy MJ, Bennett-Toomey J, Back SA, Sherman LS.

Glia. 2020 Feb;68(2):263-279. doi: 10.1002/glia.23715. Epub 2019 Sep 6.

PMID:
31490574
31.

Exome sequencing in patients with antiepileptic drug exposure and complex phenotypes.

Jackson A, Ward H, Bromley RL, Deshpande C, Vasudevan P, Scurr I, Dean J, Shannon N, Berg J, Holder S, Baralle D, Clayton-Smith J; DDD Study.

Arch Dis Child. 2019 Sep 3. pii: archdischild-2018-316547. doi: 10.1136/archdischild-2018-316547. [Epub ahead of print]

PMID:
31481360
32.

Acute flaccid myelitis: Rehabilitation challenges and outcomes in a pediatric cohort.

Melicosta ME, Dean J, Hagen K, Oppenheimer K, Porter C, Rybczynski S, Salorio C, Sadowsky C.

J Pediatr Rehabil Med. 2019;12(3):245-253. doi: 10.3233/PRM-180549.

PMID:
31476175
33.

Methods Used to Maximize Follow-Up: Lessons Learned From the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials.

Gildea MR, Moler FW, Page K, Meert K, Holubkov R, Dean JM, Christensen JR, Slomine BS.

Pediatr Crit Care Med. 2020 Jan;21(1):4-11. doi: 10.1097/PCC.0000000000002098.

PMID:
31464818
34.

Survival and Cardiopulmonary Resuscitation Hemodynamics Following Cardiac Arrest in Children With Surgical Compared to Medical Heart Disease.

Yates AR, Sutton RM, Reeder RW, Meert KL, Berger JT, Fernandez R, Wessel D, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Dean JM, Nadkarni VM, Berg RA; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Pediatr Crit Care Med. 2019 Dec;20(12):1126-1136. doi: 10.1097/PCC.0000000000002088.

PMID:
31453988
35.

Inhibition of the ubiquitous calpains protects complex I activity and enables improved mitophagy in the heart following ischemia-reperfusion.

Chen Q, Thompson J, Hu Y, Dean J, Lesnefsky EJ.

Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C910-C921. doi: 10.1152/ajpcell.00190.2019. Epub 2019 Aug 14.

PMID:
31411917
36.

Impact of Incorporating Pharmacy Residents Into a Pharmacist-Managed Culture Review Service During Weekend Staffing Commitments.

Campo M, Samai KE, Dean JE, Lund JA.

J Pharm Pract. 2019 Aug 13:897190019867489. doi: 10.1177/0897190019867489. [Epub ahead of print]

PMID:
31409208
37.

An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis.

Chen PC, Gadepalli K, MacDonald R, Liu Y, Kadowaki S, Nagpal K, Kohlberger T, Dean J, Corrado GS, Hipp JD, Mermel CH, Stumpe MC.

Nat Med. 2019 Sep;25(9):1453-1457. doi: 10.1038/s41591-019-0539-7. Epub 2019 Aug 12.

PMID:
31406351
38.

Combined LDL and VLDL Electronegativity Correlates with Coronary Heart Disease Risk in Asymptomatic Individuals.

Shen MY, Hsu JF, Chen FY, Lu J, Chang CM, Madjid M, Dean J, Dixon RAF, Shayani S, Chou TC, Chen CH.

J Clin Med. 2019 Aug 9;8(8). pii: E1193. doi: 10.3390/jcm8081193.

39.

Functional outcomes among survivors of pediatric in-hospital cardiac arrest are associated with baseline neurologic and functional status, but not with diastolic blood pressure during CPR.

Wolfe HA, Sutton RM, Reeder RW, Meert KL, Pollack MM, Yates AR, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA; Eunice Kennedy Shriver National Institute of Child Health; Human Development Collaborative Pediatric Critical Care Research Network; Pediatric Intensive Care Quality of Cardiopulmonary Resuscitation Investigators.

Resuscitation. 2019 Oct;143:57-65. doi: 10.1016/j.resuscitation.2019.08.006. Epub 2019 Aug 9.

PMID:
31404636
40.

Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes.

Sutton RM, Reeder RW, Landis WP, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).

Crit Care Med. 2019 Nov;47(11):1627-1636. doi: 10.1097/CCM.0000000000003898.

PMID:
31369424
41.

Update from RCP Quality Improvement: QI, what do we need to learn?

Dean J, Vaux E.

Future Healthc J. 2019 Jun;6(2):91-92. doi: 10.7861/futurehosp.6-2-91. No abstract available.

42.

An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort.

Kerr SM, Klaric L, Halachev M, Hayward C, Boutin TS, Meynert AM, Semple CA, Tuiskula AM, Swan H, Santoyo-Lopez J, Vitart V, Haley C, Dean J, Miedzybrodzka Z, Aitman TJ, Wilson JF.

Sci Rep. 2019 Jul 29;9(1):10964. doi: 10.1038/s41598-019-47436-6.

43.

Predicting 3-month risk for adolescent suicide attempts among pediatric emergency department patients.

King CA, Grupp-Phelan J, Brent D, Dean JM, Webb M, Bridge JA, Spirito A, Chernick LS, Mahabee-Gittens EM, Mistry RD, Rea M, Keller A, Rogers A, Shenoi R, Cwik M, Busby DR, Casper TC; Pediatric Emergency Care Applied Research Network.

J Child Psychol Psychiatry. 2019 Oct;60(10):1055-1064. doi: 10.1111/jcpp.13087. Epub 2019 Jul 21.

PMID:
31328282
44.

Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability.

Clayton-Smith J, Bromley R, Dean J, Journel H, Odent S, Wood A, Williams J, Cuthbert V, Hackett L, Aslam N, Malm H, James G, Westbom L, Day R, Ladusans E, Jackson A, Bruce I, Walker R, Sidhu S, Dyer C, Ashworth J, Hindley D, Diaz GA, Rawson M, Turnpenny P.

Orphanet J Rare Dis. 2019 Jul 19;14(1):180. doi: 10.1186/s13023-019-1064-y.

45.

Improving preparedness to respond to cross-border hepatitis A outbreaks in the European Union/European Economic Area: towards comparable sequencing of hepatitis A virus.

Enkirch T, Severi E, Vennema H, Thornton L, Dean J, Borg ML, Ciccaglione AR, Bruni R, Christova I, Ngui SL, Balogun K, Němeček V, Kontio M, Takács M, Hettmann A, Korotinska R, Löve A, Avellón A, Muñoz-Chimeno M, de Sousa R, Janta D, Epštein J, Klamer S, Suin V, Aberle SW, Holzmann H, Mellou K, Ederth JL, Sundqvist L, Roque-Afonso AM, Filipović SK, Poljak M, Vold L, Stene-Johansen K, Midgley S, Fischer TK, Faber M, Wenzel JJ, Takkinen J, Leitmeyer K.

Euro Surveill. 2019 Jul;24(28). doi: 10.2807/1560-7917.ES.2019.24.28.1800397.

46.

Reply: metrics to assess machine learning models.

Rajkomar A, Dai AM, Sun M, Hardt M, Chen K, Rough K, Dean J.

NPJ Digit Med. 2018 Oct 10;1:57. doi: 10.1038/s41746-018-0063-z. eCollection 2018. No abstract available.

47.

Implementation of a Community-Based Exercise Program for Parkinson Patients: Using Boxing as an Example.

Domingos J, Radder D, Riggare S, Godinho C, Dean J, Graziano M, de Vries NM, Ferreira J, Bloem BR.

J Parkinsons Dis. 2019;9(3):615-623. doi: 10.3233/JPD-191616.

48.

Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.

Fu Z, Ye J, Dean JW, Bostick JW, Weinberg SE, Xiong L, Oliff KN, Chen ZE, Avram D, Chandel NS, Zhou L.

Cell Rep. 2019 Jul 2;28(1):159-171.e4. doi: 10.1016/j.celrep.2019.06.024.

49.

Preface.

Dean JM, Levison SW.

Dev Neurosci. 2018;40(5-6):381. doi: 10.1159/000500983. Epub 2019 Jun 28. No abstract available.

50.

Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain.

Dean JG, Liu T, Huff S, Sheler B, Barker SA, Strassman RJ, Wang MM, Borjigin J.

Sci Rep. 2019 Jun 27;9(1):9333. doi: 10.1038/s41598-019-45812-w.

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