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Items: 39


Glutaminyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization, structure, and development as a screening platform.

Escamilla Y, Hughes CA, Abendroth J, Dranow DM, Balboa S, Dean FB, Bullard JM.

Protein Sci. 2020 Apr;29(4):905-918. doi: 10.1002/pro.3800. Epub 2019 Dec 24.


Lysyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Identification of Inhibitory Compounds.

Balboa S, Hu Y, Dean FB, Bullard JM.

SLAS Discov. 2020 Jan;25(1):57-69. doi: 10.1177/2472555219873095. Epub 2019 Sep 9.


Discovery and Characterization of Chemical Compounds That Inhibit the Function of Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa.

Corona A, Palmer SO, Zamacona R, Mendez B, Dean FB, Bullard JM.

SLAS Discov. 2018 Mar;23(3):294-301. doi: 10.1177/2472555217744559. Epub 2017 Nov 29.


Identification of Chemical Compounds That Inhibit the Function of Histidyl-tRNA Synthetase from Pseudomonas aeruginosa.

Hu Y, Palmer SO, Robles ST, Resto T, Dean FB, Bullard JM.

SLAS Discov. 2018 Jan;23(1):65-75. doi: 10.1177/2472555217722016. Epub 2017 Jul 26.


Mode of action and biochemical characterization of REP8839, a novel inhibitor of methionyl-tRNA synthetase.

Ochsner UA, Young CL, Stone KC, Dean FB, Janjic N, Critchley IA.

Antimicrob Agents Chemother. 2005 Oct;49(10):4253-62.


Unbiased whole-genome amplification directly from clinical samples.

Hosono S, Faruqi AF, Dean FB, Du Y, Sun Z, Wu X, Du J, Kingsmore SF, Egholm M, Lasken RS.

Genome Res. 2003 May;13(5):954-64. Epub 2003 Apr 14.


Comprehensive human genome amplification using multiple displacement amplification.

Dean FB, Hosono S, Fang L, Wu X, Faruqi AF, Bray-Ward P, Sun Z, Zong Q, Du Y, Du J, Driscoll M, Song W, Kingsmore SF, Egholm M, Lasken RS.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5261-6.


High-throughput genotyping of single nucleotide polymorphisms with rolling circle amplification.

Faruqi AF, Hosono S, Driscoll MD, Dean FB, Alsmadi O, Bandaru R, Kumar G, Grimwade B, Zong Q, Sun Z, Du Y, Kingsmore S, Knott T, Lasken RS.

BMC Genomics. 2001;2:4. Epub 2001 Aug 1.


Assignment of the homologue of the yeast origin recognition complex subunit ORC4 (ORC4L) to human chromosome band 2q22-->q23 by in situ hybridization and somatic cell hybrid analysis.

Eki T, Dean FB, Kohda A, Okumura K, Abe M, Murakami Y, Ishiai M, Satomoto K, Hurwitz J, O'Donnell M, Hanaoka F.

Cytogenet Cell Genet. 1998;81(1):89-90. No abstract available.


Role of the adenovirus DNA-binding protein in in vitro adeno-associated virus DNA replication.

Ward P, Dean FB, O'Donnell ME, Berns KI.

J Virol. 1998 Jan;72(1):420-7.


Isolation of human and fission yeast homologues of the budding yeast origin recognition complex subunit ORC5: human homologue (ORC5L) maps to 7q22.

Ishiai M, Dean FB, Okumura K, Abe M, Moon KY, Amin AA, Kagotani K, Taguchi H, Murakami Y, Hanaoka F, O'Donnell M, Hurwitz J, Eki T.

Genomics. 1997 Dec 1;46(2):294-8.


Two steps to binding replication origins? DNA-protein interactions.

Dean FB, O'Donnell M.

Curr Biol. 1996 Aug 1;6(8):931-4. Review.


In vitro reconstitution of human replication factor C from its five subunits.

Uhlmann F, Cai J, Flores-Rozas H, Dean FB, Finkelstein J, O'Donnell M, Hurwitz J.

Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6521-6.


Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23.

Okumura K, Nogami M, Taguchi H, Dean FB, Chen M, Pan ZQ, Hurwitz J, Shiratori A, Murakami Y, Ozawa K, et al.

Genomics. 1995 Jan 1;25(1):274-8.


Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.

Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell M, Hurwitz J.

Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8655-9.


Mapping of the 70 kDa, 34 kDa, and 11 kDa subunit genes of the human multimeric single-stranded DNA binding protein (hSSB/RPA) to chromosome bands 17p13, 1p35-p36.1, and 7p21-p22.

Ozawa K, Dean FB, Chen M, Lee SH, Shiratori A, Murakami Y, Sakakura T, Hurwitz J, Eki T.

Cell Struct Funct. 1993 Aug;18(4):221-30.


Homology in accessory proteins of replicative polymerases--E. coli to humans.

O'Donnell M, Onrust R, Dean FB, Chen M, Hurwitz J.

Nucleic Acids Res. 1993 Jan 11;21(1):1-3. No abstract available.


The simian virus 40 T antigen double hexamer assembles around the DNA at the replication origin.

Dean FB, Borowiec JA, Eki T, Hurwitz J.

J Biol Chem. 1992 Jul 15;267(20):14129-37.


Simian virus 40 large T antigen untwists DNA at the origin of DNA replication.

Dean FB, Hurwitz J.

J Biol Chem. 1991 Mar 15;266(8):5062-71.


The in vitro replication of DNA containing the SV40 origin.

Hurwitz J, Dean FB, Kwong AD, Lee SH.

J Biol Chem. 1990 Oct 25;265(30):18043-6. Review. No abstract available.


Binding and unwinding--how T antigen engages the SV40 origin of DNA replication.

Borowiec JA, Dean FB, Bullock PA, Hurwitz J.

Cell. 1990 Jan 26;60(2):181-4. Review. No abstract available.


ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication.

Mastrangelo IA, Hough PV, Wall JS, Dodson M, Dean FB, Hurwitz J.

Nature. 1989 Apr 20;338(6217):658-62.


An inhibitor of the in vitro elongation reaction of simian virus 40 DNA replication is overcome by proliferating-cell nuclear antigen.

Lee SH, Ishimi Y, Kenny MK, Bullock P, Dean FB, Hurwitz J.

Proc Natl Acad Sci U S A. 1988 Dec;85(24):9469-73.


In vitro replication of DNA containing either the SV40 or the polyoma origin.

Wobbe CR, Dean FB, Murakami Y, Borowiec JA, Bullock P, Hurwitz J.

Philos Trans R Soc Lond B Biol Sci. 1987 Dec 15;317(1187):439-53.


Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro.

Dean FB, Borowiec JA, Ishimi Y, Deb S, Tegtmeyer P, Hurwitz J.

Proc Natl Acad Sci U S A. 1987 Dec;84(23):8267-71.


Unwinding of duplex DNA from the SV40 origin of replication by T antigen.

Dodson M, Dean FB, Bullock P, Echols H, Hurwitz J.

Science. 1987 Nov 13;238(4829):964-7. Erratum in: Science 1987 Dec 4;238(4832):1341.


Replication of simian virus 40 origin-containing DNA in vitro with purified proteins.

Wobbe CR, Weissbach L, Borowiec JA, Dean FB, Murakami Y, Bullock P, Hurwitz J.

Proc Natl Acad Sci U S A. 1987 Apr;84(7):1834-8.


Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.

Dean FB, Bullock P, Murakami Y, Wobbe CR, Weissbach L, Hurwitz J.

Proc Natl Acad Sci U S A. 1987 Jan;84(1):16-20.


Simian virus 40 DNA replication in vitro: study of events preceding elongation of chains.

Wobbe CR, Dean FB, Murakami Y, Weissbach L, Hurwitz J.

Proc Natl Acad Sci U S A. 1986 Jul;83(13):4612-6.


Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.

Murakami Y, Wobbe CR, Weissbach L, Dean FB, Hurwitz J.

Proc Natl Acad Sci U S A. 1986 May;83(9):2869-73.


Duplex DNA knots produced by Escherichia coli topoisomerase I. Structure and requirements for formation.

Dean FB, Stasiak A, Koller T, Cozzarelli NR.

J Biol Chem. 1985 Apr 25;260(8):4975-83.


Replication of bacteriophage T7 DNA by purified proteins.

Richardson CC, Romano LJ, Kolodner R, LeClerc JE, Tamanoi F, Engler MJ, Dean FB, Richardson DS.

Cold Spring Harb Symp Quant Biol. 1979;43 Pt 1:427-40. No abstract available.


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