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Items: 11


Terminal Alkynes as Raman Probes of α-Synuclein in Solution and in Cells.

Flynn JD, Gimmen MY, Dean DN, Lacy SM, Lee JC.

Chembiochem. 2020 Jan 21. doi: 10.1002/cbic.202000026. [Epub ahead of print]


Large fatty acid-derived Aβ42 oligomers form ring-like assemblies.

Xi W, Dean DN, Stockmal KA, Morgan SE, Hansmann UHE, Rangachari V.

J Chem Phys. 2019 Feb 21;150(7):075101. doi: 10.1063/1.5082659.


Cysteine-rich granulin-3 rapidly promotes amyloid-β fibrils in both redox states.

Bhopatkar AA, Ghag G, Wolf LM, Dean DN, Moss MA, Rangachari V.

Biochem J. 2019 Mar 12;476(5):859-873. doi: 10.1042/BCJ20180916.


pH-Dependent fibril maturation of a Pmel17 repeat domain isoform revealed by tryptophan fluorescence.

Dean DN, Lee JC.

Biochim Biophys Acta Proteins Proteom. 2019 Oct;1867(10):961-969. doi: 10.1016/j.bbapap.2019.01.012. Epub 2019 Feb 2.


Cause and consequence of Aβ - Lipid interactions in Alzheimer disease pathogenesis.

Rangachari V, Dean DN, Rana P, Vaidya A, Ghosh P.

Biochim Biophys Acta Biomembr. 2018 Mar 9. pii: S0005-2736(18)30084-1. doi: 10.1016/j.bbamem.2018.03.004. [Epub ahead of print] Review.


Propagation of an Aβ Dodecamer Strain Involves a Three-Step Mechanism and a Key Intermediate.

Dean DN, Rana P, Campbell RP, Ghosh P, Rangachari V.

Biophys J. 2018 Feb 6;114(3):539-549. doi: 10.1016/j.bpj.2017.11.3778.


Aqueous RAFT Synthesis of Glycopolymers for Determination of Saccharide Structure and Concentration Effects on Amyloid β Aggregation.

Das PK, Dean DN, Fogel AL, Liu F, Abel BA, McCormick CL, Kharlampieva E, Rangachari V, Morgan SE.

Biomacromolecules. 2017 Oct 9;18(10):3359-3366. doi: 10.1021/acs.biomac.7b01007. Epub 2017 Sep 26.


Fatty Acid Concentration and Phase Transitions Modulate Aβ Aggregation Pathways.

Rana P, Dean DN, Steen ED, Vaidya A, Rangachari V, Ghosh P.

Sci Rep. 2017 Sep 4;7(1):10370. doi: 10.1038/s41598-017-09794-x.


Strain-specific Fibril Propagation by an Aβ Dodecamer.

Dean DN, Das PK, Rana P, Burg F, Levites Y, Morgan SE, Ghosh P, Rangachari V.

Sci Rep. 2017 Jan 18;7:40787. doi: 10.1038/srep40787.


Conformational Dynamics of Specific Aβ Oligomers Govern Their Ability To Replicate and Induce Neuronal Apoptosis.

Dean DN, Pate KM, Moss MA, Rangachari V.

Biochemistry. 2016 Apr 19;55(15):2238-50. doi: 10.1021/acs.biochem.6b00161. Epub 2016 Apr 7.


Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease.

Kumar A, Pate KM, Moss MA, Dean DN, Rangachari V.

PLoS One. 2014 Nov 3;9(11):e111492. doi: 10.1371/journal.pone.0111492. eCollection 2014.

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