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Emerging next-generation sequencing-based discoveries for targeted osteosarcoma therapy.

Zhao J, Dean DC, Hornicek FJ, Yu X, Duan Z.

Cancer Lett. 2020 Apr 1;474:158-167. doi: 10.1016/j.canlet.2020.01.020. Epub 2020 Jan 24.


Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells.

Chen F, Liu X, Chen Y, Liu JY, Lu H, Wang W, Lu X, Dean KC, Gao L, Kaplan HJ, Dean DC, Peng X, Liu Y.

EBioMedicine. 2020 Jan 23;52:102618. doi: 10.1016/j.ebiom.2019.102618. [Epub ahead of print]


Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067.

Shen S, Dean DC, Yu Z, Hornicek F, Kan Q, Duan Z.

J Cancer. 2020 Jan 1;11(1):132-141. doi: 10.7150/jca.35426. eCollection 2020.


Cortical Microstructural Alterations in Mild Cognitive Impairment and Alzheimer's Disease Dementia.

Vogt NM, Hunt JF, Adluru N, Dean DC, Johnson SC, Asthana S, Yu JJ, Alexander AL, Bendlin BB.

Cereb Cortex. 2019 Dec 13. pii: bhz286. doi: 10.1093/cercor/bhz286. [Epub ahead of print]


The development of the social brain in baby siblings of children with autism.

Dean DC 3rd, Freeman A, Lainhart J.

Curr Opin Psychiatry. 2020 Mar;33(2):110-116. doi: 10.1097/YCO.0000000000000572.


Chimeric antigen receptor T (CAR-T) cell immunotherapy for sarcomas: From mechanisms to potential clinical applications.

Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ, Duan Z.

Cancer Treat Rev. 2020 Jan;82:101934. doi: 10.1016/j.ctrv.2019.101934. Epub 2019 Nov 25. Review.


Establishment and Characterization of a Recurrent Osteosarcoma Cell Line: OSA 1777.

Thanindratarn P, Li X, Dean DC, Nelson SD, Hornicek FJ, Duan Z.

J Orthop Res. 2019 Nov 18. doi: 10.1002/jor.24528. [Epub ahead of print]


Cancer Testis Antigens in Sarcoma: Expression, Function and Immunotherapeutic Application.

Wei R, Dean DC, Thanindratarn P, Hornicek FJ, Guo W, Duan Z.

Cancer Lett. 2019 Oct 18. pii: S0304-3835(19)30521-X. doi: 10.1016/j.canlet.2019.10.024. [Epub ahead of print]


Exosomes promote pre-metastatic niche formation in ovarian cancer.

Feng W, Dean DC, Hornicek FJ, Shi H, Duan Z.

Mol Cancer. 2019 Aug 13;18(1):124. doi: 10.1186/s12943-019-1049-4. Review.


ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells.

de Barrios O, Sanchez-Moral L, Cortés M, Ninfali C, Profitós-Pelejà N, Martínez-Campanario MC, Siles L, Del Campo R, Fernández-Aceñero MJ, Darling DS, Castells A, Maurel J, Salas A, Dean DC, Postigo A.

Gut. 2019 Dec;68(12):2129-2141. doi: 10.1136/gutjnl-2018-317294. Epub 2019 Jul 31.


Metabolic Deregulation of the Blood-Outer Retinal Barrier in Retinitis Pigmentosa.

Wang W, Kini A, Wang Y, Liu T, Chen Y, Vukmanic E, Emery D, Liu Y, Lu X, Jin L, Lee SJ, Scott P, Liu X, Dean K, Lu Q, Fortuny E, James R, Kaplan HJ, Du J, Dean DC.

Cell Rep. 2019 Jul 30;28(5):1323-1334.e4. doi: 10.1016/j.celrep.2019.06.093.


Elevated Insulin and Insulin Resistance are Associated with Altered Myelin in Cognitively Unimpaired Middle-Aged Adults.

O'Grady JP, Dean DC 3rd, Yang KL, Canda CM, Hoscheidt SM, Starks EJ, Merluzzi A, Hurley S, Davenport NJ, Okonkwo OC, Anderson RM, Asthana S, Johnson SC, Alexander AL, Bendlin BB.

Obesity (Silver Spring). 2019 Sep;27(9):1464-1471. doi: 10.1002/oby.22558. Epub 2019 Jul 17.


Generalizability and reproducibility of functional connectivity in autism.

King JB, Prigge MBD, King CK, Morgan J, Weathersby F, Fox JC, Dean DC 3rd, Freeman A, Villaruz JAM, Kane KL, Bigler ED, Alexander AL, Lange N, Zielinski B, Lainhart JE, Anderson JS.

Mol Autism. 2019 Jun 24;10:27. doi: 10.1186/s13229-019-0273-5. eCollection 2019.


Mindfulness-Based Stress Reduction-related changes in posterior cingulate resting brain connectivity.

Kral TRA, Imhoff-Smith T, Dean DC, Grupe D, Adluru N, Patsenko E, Mumford JA, Goldman R, Rosenkranz MA, Davidson RJ.

Soc Cogn Affect Neurosci. 2019 Jul 31;14(7):777-787. doi: 10.1093/scan/nsz050.


A simple sleep EEG marker in childhood predicts brain myelin 3.5 years later.

LeBourgeois MK, Dean DC, Deoni SCL, Kohler M, Kurth S.

Neuroimage. 2019 Oct 1;199:342-350. doi: 10.1016/j.neuroimage.2019.05.072. Epub 2019 Jun 3.


Role of cyclin-dependent kinases (CDKs) in hepatocellular carcinoma: Therapeutic potential of targeting the CDK signaling pathway.

Shen S, Dean DC, Yu Z, Duan Z.

Hepatol Res. 2019 Oct;49(10):1097-1108. doi: 10.1111/hepr.13353. Epub 2019 May 26.


Advances in immune checkpoint inhibitors for bone sarcoma therapy.

Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ, Duan Z.

J Bone Oncol. 2019 Jan 29;15:100221. doi: 10.1016/j.jbo.2019.100221. eCollection 2019 Apr. Review.


Cyclin-dependent kinase 9 (CDK9) is a novel prognostic marker and therapeutic target in ovarian cancer.

Wang J, Dean DC, Hornicek FJ, Shi H, Duan Z.

FASEB J. 2019 May;33(5):5990-6000. doi: 10.1096/fj.201801789RR. Epub 2019 Feb 6.


Evaluation of Differences in Temporal Synchrony Between Brain Regions in Individuals With Autism and Typical Development.

King JB, Prigge MBD, King CK, Morgan J, Dean DC 3rd, Freeman A, Villaruz JAM, Kane KL, Bigler ED, Alexander AL, Lange N, Zielinski BA, Lainhart JE, Anderson JS.

JAMA Netw Open. 2018 Nov 2;1(7):e184777. doi: 10.1001/jamanetworkopen.2018.4777.


Effects of Delayed Cord Clamping on 4-Month Ferritin Levels, Brain Myelin Content, and Neurodevelopment: A Randomized Controlled Trial.

Mercer JS, Erickson-Owens DA, Deoni SCL, Dean DC 3rd, Collins J, Parker AB, Wang M, Joelson S, Mercer EN, Padbury JF.

J Pediatr. 2018 Dec;203:266-272.e2. doi: 10.1016/j.jpeds.2018.06.006. Epub 2018 Jul 6.


Standing Balance on Unsteady Surfaces in Children on the Autism Spectrum: The Effects of IQ.

Travers BG, Mason A, Gruben KG, Dean DC 3rd, McLaughlin K.

Res Autism Spectr Disord. 2018 Jul;51:9-17. doi: 10.1016/j.rasd.2018.03.008. Epub 2018 Mar 31.


RNA sequencing (RNA-Seq) and its application in ovarian cancer.

Wang J, Dean DC, Hornicek FJ, Shi H, Duan Z.

Gynecol Oncol. 2019 Jan;152(1):194-201. doi: 10.1016/j.ygyno.2018.10.002. Epub 2018 Oct 5. Review.


Epigenetically distinct sister chromatids and asymmetric generation of tumor initiating cells.

Liu Y, Siles L, Postigo A, Dean DC.

Cell Cycle. 2018;17(18):2221-2229. doi: 10.1080/15384101.2018.1532254. Epub 2018 Oct 13. Review.


Association of Prenatal Maternal Depression and Anxiety Symptoms With Infant White Matter Microstructure.

Dean DC 3rd, Planalp EM, Wooten W, Kecskemeti SR, Adluru N, Schmidt CK, Frye C, Birn RM, Burghy CA, Schmidt NL, Styner MA, Short SJ, Kalin NH, Goldsmith HH, Alexander AL, Davidson RJ.

JAMA Pediatr. 2018 Oct 1;172(10):973-981. doi: 10.1001/jamapediatrics.2018.2132.


From genomics to metabolomics: emerging metastatic biomarkers in osteosarcoma.

Dean DC, Shen S, Hornicek FJ, Duan Z.

Cancer Metastasis Rev. 2018 Dec;37(4):719-731. doi: 10.1007/s10555-018-9763-8. Review.


Human amygdala functional network development: A cross-sectional study from 3 months to 5 years of age.

Gabard-Durnam LJ, O'Muircheartaigh J, Dirks H, Dean DC 3rd, Tottenham N, Deoni S.

Dev Cogn Neurosci. 2018 Nov;34:63-74. doi: 10.1016/j.dcn.2018.06.004. Epub 2018 Jul 21.


Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells.

Liu Y, Siles L, Lu X, Dean KC, Cuatrecasas M, Postigo A, Dean DC.

Nat Commun. 2018 Jun 21;9(1):2424. doi: 10.1038/s41467-018-04663-1.


Prospective study of myelin water fraction changes after mild traumatic brain injury in collegiate contact sports.

Spader HS, Dean DC, LaFrance WC, Raukar NP, Cosgrove GR, Eyerly-Webb SA, Ellermeier A, Correia S, Deoni SCL, Rogg J.

J Neurosurg. 2018 Apr 1:1-9. doi: 10.3171/2017.12.JNS171597. [Epub ahead of print]


Correction to: Investigation of brain structure in the 1-month infant.

Dean DC 3rd, Planalp EM, Wooten W, Schmidt CK, Kecskemeti SR, Frye C, Schmidt NL, Goldsmith HH, Alexander AL, Davidson RJ.

Brain Struct Funct. 2018 Jul;223(6):3007-3009. doi: 10.1007/s00429-018-1643-z.


Investigation of brain structure in the 1-month infant.

Dean DC 3rd, Planalp EM, Wooten W, Schmidt CK, Kecskemeti SR, Frye C, Schmidt NL, Goldsmith HH, Alexander AL, Davidson RJ.

Brain Struct Funct. 2018 May;223(4):1953-1970. doi: 10.1007/s00429-017-1600-2. Epub 2018 Jan 5. Erratum in: Brain Struct Funct. 2018 Mar 10;:.


Longitudinal development of thalamic and internal capsule microstructure in autism spectrum disorder.

McLaughlin K, Travers BG, Dadalko OI, Dean DC 3rd, Tromp D, Adluru N, Destiche D, Freeman A, Prigge MD, Froehlich A, Duffield TC, Zielinski BA, Bigler ED, Lange N, Anderson JS, Alexander AL, Lainhart JE.

Autism Res. 2018 Mar;11(3):450-462. doi: 10.1002/aur.1909. Epub 2017 Dec 18.


Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles.

Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A.

EMBO J. 2017 Nov 15;36(22):3336-3355. doi: 10.15252/embj.201797345. Epub 2017 Oct 16.


Evaluation of striatonigral connectivity using probabilistic tractography in Parkinson's disease.

Theisen F, Leda R, Pozorski V, Oh JM, Adluru N, Wong R, Okonkwo O, Dean DC 3rd, Bendlin BB, Johnson SC, Alexander AL, Gallagher CL.

Neuroimage Clin. 2017 Sep 9;16:557-563. doi: 10.1016/j.nicl.2017.09.009. eCollection 2017.


Traveling Slow Oscillations During Sleep: A Marker of Brain Connectivity in Childhood.

Kurth S, Riedner BA, Dean DC, O'Muircheartaigh J, Huber R, Jenni OG, Deoni SCL, LeBourgeois MK.

Sleep. 2017 Sep 1;40(9). doi: 10.1093/sleep/zsx121.


Biofeedback-Based, Videogame Balance Training in Autism.

Travers BG, Mason AH, Mrotek LA, Ellertson A, Dean DC 3rd, Engel C, Gomez A, Dadalko OI, McLaughlin K.

J Autism Dev Disord. 2018 Jan;48(1):163-175. doi: 10.1007/s10803-017-3310-2.


Restoration of Cone Photoreceptor Function in Retinitis Pigmentosa.

Kaplan HJ, Wang W, Dean DC.

Transl Vis Sci Technol. 2017 Sep 6;6(5):5. doi: 10.1167/tvst.6.5.5. eCollection 2017 Sep. Review. No abstract available.


Mapping White Matter Microstructure in the One Month Human Brain.

Dean DC 3rd, Planalp EM, Wooten W, Adluru N, Kecskemeti SR, Frye C, Schmidt CK, Schmidt NL, Styner MA, Goldsmith HH, Davidson RJ, Alexander AL.

Sci Rep. 2017 Aug 29;7(1):9759. doi: 10.1038/s41598-017-09915-6.


Quantifying cortical development in typically developing toddlers and young children, 1-6 years of age.

Remer J, Croteau-Chonka E, Dean DC 3rd, D'Arpino S, Dirks H, Whiley D, Deoni SCL.

Neuroimage. 2017 Jun;153:246-261. doi: 10.1016/j.neuroimage.2017.04.010. Epub 2017 Apr 6.


ZEB1 Regulates Multiple Oncogenic Components Involved in Uveal Melanoma Progression.

Chen Y, Lu X, Montoya-Durango DE, Liu YH, Dean KC, Darling DS, Kaplan HJ, Dean DC, Gao L, Liu Y.

Sci Rep. 2017 Mar 3;7(1):45. doi: 10.1038/s41598-017-00079-x.


Sphere-Induced Rejuvenation of Swine and Human Müller Glia Is Primarily Caused by Telomere Elongation.

Xu N, Chen Y, Dean KC, Lu X, Liu X, Wang W, Dean DC, Kaplan HJ, Gao L, Dong F, Liu Y.

Stem Cells. 2017 Jun;35(6):1579-1591. doi: 10.1002/stem.2585. Epub 2017 Mar 5.


Multivariate characterization of white matter heterogeneity in autism spectrum disorder.

Dean DC 3rd, Lange N, Travers BG, Prigge MB, Matsunami N, Kellett KA, Freeman A, Kane KL, Adluru N, Tromp DP, Destiche DJ, Samsin D, Zielinski BA, Fletcher PT, Anderson JS, Froehlich AL, Leppert MF, Bigler ED, Lainhart JE, Alexander AL.

Neuroimage Clin. 2017 Jan 6;14:54-66. doi: 10.1016/j.nicl.2017.01.002. eCollection 2017.


Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells.

Schreck C, Istvánffy R, Ziegenhain C, Sippenauer T, Ruf F, Henkel L, Gärtner F, Vieth B, Florian MC, Mende N, Taubenberger A, Prendergast Á, Wagner A, Pagel C, Grziwok S, Götze KS, Guck J, Dean DC, Massberg S, Essers M, Waskow C, Geiger H, Schiemann M, Peschel C, Enard W, Oostendorp RA.

J Exp Med. 2017 Jan;214(1):165-181. doi: 10.1084/jem.20151414. Epub 2016 Dec 20.


Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease.

Dean DC 3rd, Hurley SA, Kecskemeti SR, O'Grady JP, Canda C, Davenport-Sis NJ, Carlsson CM, Zetterberg H, Blennow K, Asthana S, Sager MA, Johnson SC, Alexander AL, Bendlin BB.

JAMA Neurol. 2017 Jan 1;74(1):41-49. doi: 10.1001/jamaneurol.2016.3232.


Increased Sleep Depth in Developing Neural Networks: New Insights from Sleep Restriction in Children.

Kurth S, Dean DC 3rd, Achermann P, O'Muircheartaigh J, Huber R, Deoni SC, LeBourgeois MK.

Front Hum Neurosci. 2016 Sep 21;10:456. eCollection 2016.


Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study.

Dean DC 3rd, Sojkova J, Hurley S, Kecskemeti S, Okonkwo O, Bendlin BB, Theisen F, Johnson SC, Alexander AL, Gallagher CL.

PLoS One. 2016 Oct 5;11(10):e0163774. doi: 10.1371/journal.pone.0163774. eCollection 2016.


Age-dependent differences in brain tissue microstructure assessed with neurite orientation dispersion and density imaging.

Merluzzi AP, Dean DC 3rd, Adluru N, Suryawanshi GS, Okonkwo OC, Oh JM, Hermann BP, Sager MA, Asthana S, Zhang H, Johnson SC, Alexander AL, Bendlin BB.

Neurobiol Aging. 2016 Jul;43:79-88. doi: 10.1016/j.neurobiolaging.2016.03.026. Epub 2016 Apr 6.


Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa.

Wang W, Lee SJ, Scott PA, Lu X, Emery D, Liu Y, Ezashi T, Roberts MR, Ross JW, Kaplan HJ, Dean DC.

Cell Rep. 2016 Apr 12;15(2):372-85. doi: 10.1016/j.celrep.2016.03.022. Epub 2016 Mar 31.


Investigating the Microstructural Correlation of White Matter in Autism Spectrum Disorder.

Dean DC 3rd, Travers BG, Adluru N, Tromp do PM, Destiche DJ, Samsin D, Prigge MB, Zielinski BA, Fletcher PT, Anderson JS, Froehlich AL, Bigler ED, Lange N, Lainhart JE, Alexander AL.

Brain Connect. 2016 Jun;6(5):415-33. doi: 10.1089/brain.2015.0385. Epub 2016 May 5.


Mapping an index of the myelin g-ratio in infants using magnetic resonance imaging.

Dean DC 3rd, O'Muircheartaigh J, Dirks H, Travers BG, Adluru N, Alexander AL, Deoni SCL.

Neuroimage. 2016 May 15;132:225-237. doi: 10.1016/j.neuroimage.2016.02.040. Epub 2016 Feb 22.


Examining the relationships between cortical maturation and white matter myelination throughout early childhood.

Croteau-Chonka EC, Dean DC 3rd, Remer J, Dirks H, O'Muircheartaigh J, Deoni SCL.

Neuroimage. 2016 Jan 15;125:413-421. doi: 10.1016/j.neuroimage.2015.10.038. Epub 2015 Oct 21.

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