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Items: 7

1.

Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.

Malecka KA, Dheekollu J, Deakyne JS, Wiedmer A, Ramirez UD, Lieberman PM, Messick TE.

J Virol. 2019 Sep 30;93(20). pii: e00487-19. doi: 10.1128/JVI.00487-19. Print 2019 Oct 15.

PMID:
31142669
2.

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau5612. doi: 10.1126/scitranslmed.aau5612.

PMID:
30842315
3.

Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.

Deakyne JS, Malecka KA, Messick TE, Lieberman PM.

J Virol. 2017 Sep 12;91(19). pii: e01046-17. doi: 10.1128/JVI.01046-17. Print 2017 Oct 1.

4.

Analysis of the activities of RAD54, a SWI2/SNF2 protein, using a specific small-molecule inhibitor.

Deakyne JS, Huang F, Negri J, Tolliday N, Cocklin S, Mazin AV.

J Biol Chem. 2013 Nov 1;288(44):31567-80. doi: 10.1074/jbc.M113.502195. Epub 2013 Sep 16.

5.

Polarity and bypass of DNA heterology during branch migration of Holliday junctions by human RAD54, BLM, and RECQ1 proteins.

Mazina OM, Rossi MJ, Deakyne JS, Huang F, Mazin AV.

J Biol Chem. 2012 Apr 6;287(15):11820-32. doi: 10.1074/jbc.M112.341347. Epub 2012 Feb 22.

6.

Fanconi anemia: at the crossroads of DNA repair.

Deakyne JS, Mazin AV.

Biochemistry (Mosc). 2011 Jan;76(1):36-48. Review.

PMID:
21568838
7.

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.

Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr.

Blood. 2010 Nov 11;116(19):3780-91. doi: 10.1182/blood-2009-11-256016. Epub 2010 Jul 16.

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