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Items: 6

1.

Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia.

Ogoshi Y, Matsui T, Mitani I, Yokota M, Terashita M, Motoda D, Ueyama K, Hotta T, Ito T, Hase Y, Fukui K, Deai K, Yoshiuchi H, Ito S, Abe H.

ACS Med Chem Lett. 2017 Nov 20;8(12):1320-1325. doi: 10.1021/acsmedchemlett.7b00404. eCollection 2017 Dec 14.

2.

JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation.

Kurimoto T, Tamai I, Miyai A, Kosugi Y, Nakagawa T, Yamamoto Y, Deai K, Misaki S, Bessho Y, Negoro T, Yamaguchi T, Hata T, Matsushita M.

Eur J Pharmacol. 2017 May 15;803:179-186. doi: 10.1016/j.ejphar.2017.03.057. Epub 2017 Mar 31.

PMID:
28366807
3.

Pharmacological characterization of (3S)-3-(hydroxymethyl)-4-(5-methylpyridin-2-yl)-N-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide (JTS-653), a novel transient receptor potential vanilloid 1 antagonist.

Kitagawa Y, Miyai A, Usui K, Hamada Y, Deai K, Wada M, Koga Y, Sakata M, Hayashi M, Tominaga M, Matsushita M.

J Pharmacol Exp Ther. 2012 Aug;342(2):520-8. doi: 10.1124/jpet.112.194027. Epub 2012 May 15.

PMID:
22588258
4.

Prostaglandin E2 stimulates granulocyte colony-stimulating factor production via the prostanoid EP2 receptor in mouse peritoneal neutrophils.

Sugimoto Y, Fukada Y, Mori D, Tanaka S, Yamane H, Okuno Y, Deai K, Tsuchiya S, Tsujimoto G, Ichikawa A.

J Immunol. 2005 Aug 15;175(4):2606-12.

5.

Expression of L-histidine decarboxylase in granules of elicited mouse polymorphonuclear leukocytes.

Tanaka S, Deai K, Konomi A, Takahashi K, Yamane H, Sugimoto Y, Ichikawa A.

Eur J Immunol. 2004 May;34(5):1472-82.

6.

Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7.

Tanaka S, Deai K, Inagaki M, Ichikawa A.

Am J Physiol Cell Physiol. 2003 Sep;285(3):C592-8. Epub 2003 Apr 30.

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