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Risks of preterm birth among non-Hispanic black and non-Hispanic white women: Effect modification by maternal age.

Keiser AM, Salinas YD, DeWan AT, Hawley NL, Donohue PK, Strobino DM.

Paediatr Perinat Epidemiol. 2019 Sep;33(5):346-356. doi: 10.1111/ppe.12572. Epub 2019 Jul 31.


Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome.

Brown AL, de Smith AJ, Gant VU, Yang W, Scheurer ME, Walsh KM, Chernus JM, Kallsen NA, Peyton SA, Davies GE, Ehli EA, Winick N, Heerema NA, Carroll AJ, Borowitz MJ, Wood BL, Carroll WL, Raetz EA, Feingold E, Devidas M, Barcellos LF, Hansen HM, Morimoto L, Kang AY, Smirnov I, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson P, Spector LG, Pombo-de-Oliveira MS, DeWan AT, Mullighan CG, Hunger SP, Pui CH, Loh ML, Zwick ME, Metayer C, Ma X, Mueller BA, Sherman SL, Wiemels JL, Relling MV, Yang JJ, Lupo PJ, Rabin KR.

Blood. 2019 Oct 10;134(15):1227-1237. doi: 10.1182/blood.2018890764.


Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome.

de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antillón F, Girón V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL.

Leukemia. 2019 Nov;33(11):2746-2751. doi: 10.1038/s41375-019-0514-9. Epub 2019 Jul 11. No abstract available.



Spector LG, DeWan AT, Pankratz ND, Turcotte LM, Yang JJ, Scheurer ME.

Am J Epidemiol. 2019 Jun 1;188(6):1192-1193. doi: 10.1093/aje/kwz075. No abstract available.


Association of iron status with the risk of bloodstream infections: results from the prospective population-based HUNT Study in Norway.

Mohus RM, Paulsen J, Gustad L, Askim Å, Mehl A, DeWan AT, Afset JE, Åsvold BO, Solligård E, Damås JK.

Intensive Care Med. 2018 Aug;44(8):1276-1283. doi: 10.1007/s00134-018-5320-8. Epub 2018 Jul 23.


MendelProb: probability and sample size calculations for Mendelian studies of exome and whole genome sequence data.

He Z, Wang L, DeWan AT, Leal SM.

Bioinformatics. 2019 Feb 1;35(3):529-531. doi: 10.1093/bioinformatics/bty542.


Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1.

Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R.

Hypertension. 2018 Aug;72(2):408-416. doi: 10.1161/HYPERTENSIONAHA.117.10688. Epub 2018 Jul 2.


Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis.

Cahill ME, Conley S, DeWan AT, Montgomery RR.

BMC Infect Dis. 2018 Jun 22;18(1):282. doi: 10.1186/s12879-018-3186-6.


BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia.

de Smith AJ, Walsh KM, Francis SS, Zhang C, Hansen HM, Smirnov I, Morimoto L, Whitehead TP, Kang A, Shao X, Barcellos LF, McKean-Cowdin R, Zhang L, Fu C, Wang R, Yu H, Hoh J, Dewan AT, Metayer C, Ma X, Wiemels JL.

Int J Cancer. 2018 Dec 1;143(11):2647-2658. doi: 10.1002/ijc.31622. Epub 2018 Oct 3.


Gene-Gene and Gene-Environment Interactions.

DeWan AT.

Methods Mol Biol. 2018;1793:89-110. doi: 10.1007/978-1-4939-7868-7_7.


Association of CACNA1C with bipolar disorder among the Pakistani population.

Khalid M, Driessen TM, Lee JS, Tejwani L, Rasool A, Saqlain M, Shiaq PA, Hanif M, Nawaz A, DeWan AT, Raja GK, Lim J.

Gene. 2018 Jul 20;664:119-126. doi: 10.1016/j.gene.2018.04.061. Epub 2018 Apr 22.


GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.

Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X.

Nat Commun. 2018 Jan 18;9(1):286. doi: 10.1038/s41467-017-02596-9.


Statistical Analysis of Multiple Phenotypes in Genetic Epidemiologic Studies: From Cross-Phenotype Associations to Pleiotropy.

Salinas YD, Wang Z, DeWan AT.

Am J Epidemiol. 2018 Apr 1;187(4):855-863. doi: 10.1093/aje/kwx296. Review.


Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews.

Streicher SA, Klein AP, Olson SH, Amundadottir LT, DeWan AT, Zhao H, Risch HA.

Cancer Epidemiol Biomarkers Prev. 2017 Oct;26(10):1540-1548. doi: 10.1158/1055-9965.EPI-17-0262. Epub 2017 Jul 28.


Parental Age and Risk of Pediatric Cancer in the Offspring: A Population-Based Record-Linkage Study in California.

Wang R, Metayer C, Morimoto L, Wiemels JL, Yang J, DeWan AT, Kang A, Ma X.

Am J Epidemiol. 2017 Oct 1;186(7):843-856. doi: 10.1093/aje/kwx160.


Predictors of tanning dependence in white non-Hispanic females and males.

Cartmel B, Bale AE, Mayne ST, Gelernter JE, DeWan AT, Spain P, Leffell DJ, Pagoto S, Ferrucci LM.

J Eur Acad Dermatol Venereol. 2017 Jul;31(7):1223-1228. doi: 10.1111/jdv.14138. Epub 2017 Feb 21.


Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California.

Wang R, Wiemels JL, Metayer C, Morimoto L, Francis SS, Kadan-Lottick N, DeWan AT, Zhang Y, Ma X.

Am J Epidemiol. 2017 Jan 15;185(2):96-105. doi: 10.1093/aje/kww153. Epub 2016 Dec 16.


Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California.

Triebwasser C, Wang R, DeWan AT, Metayer C, Morimoto L, Wiemels JL, Kadan-Lottick N, Ma X.

Eur J Cancer. 2016 Dec;69:19-27. doi: 10.1016/j.ejca.2016.09.016. Epub 2016 Nov 1.


Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia.

Spracklen CN, Smith CJ, Saftlas AF, Triche EW, Bjonnes A, Keating BJ, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK.

Hypertens Pregnancy. 2017 Feb;36(1):30-35. doi: 10.1080/10641955.2016.1223303. Epub 2016 Sep 22.


Genome-wide search identifies a gene-gene interaction between 20p13 and 2q14 in asthma.

Murk W, DeWan AT.

BMC Genet. 2016 Jul 7;17(1):102. doi: 10.1186/s12863-016-0376-3.


Gene-based analysis identified the gene ZNF248 is associated with late-onset asthma in African Americans.

Wang L, Salinas YD, DeWan AT.

Ann Allergy Asthma Immunol. 2016 Jul;117(1):50-55.e2. doi: 10.1016/j.anai.2016.05.005. Epub 2016 May 27.


Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993-2011: an observational study.

Askim Å, Mehl A, Paulsen J, DeWan AT, Vestrheim DF, Åsvold BO, Damås JK, Solligård E.

BMC Infect Dis. 2016 May 23;16:223. doi: 10.1186/s12879-016-1553-8.


PIWI-Interacting RNAs in Gliomagenesis: Evidence from Post-GWAS and Functional Analyses.

Jacobs DI, Qin Q, Lerro MC, Fu A, Dubrow R, Claus EB, DeWan AT, Wang G, Lin H, Zhu Y.

Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1073-80. doi: 10.1158/1055-9965.EPI-16-0047. Epub 2016 May 13.


Exhaustive Genome-Wide Search for SNP-SNP Interactions Across 10 Human Diseases.

Murk W, DeWan AT.

G3 (Bethesda). 2016 Jul 7;6(7):2043-50. doi: 10.1534/g3.116.028563.


dbPEC: a comprehensive literature-based database for preeclampsia related genes and phenotypes.

Uzun A, Triche EW, Schuster J, Dewan AT, Padbury JF.

Database (Oxford). 2016 Mar 5;2016. pii: baw006. doi: 10.1093/database/baw006. Print 2016.


Genome-Wide Gene by Environment Interaction Analysis Identifies Common SNPs at 17q21.2 that Are Associated with Increased Body Mass Index Only among Asthmatics.

Wang L, Murk W, DeWan AT.

PLoS One. 2015 Dec 16;10(12):e0144114. doi: 10.1371/journal.pone.0144114. eCollection 2015.


Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia.

Smith CJ, Saftlas AF, Spracklen CN, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK.

Am J Hypertens. 2016 Jan;29(1):17-24. doi: 10.1093/ajh/hpv069. Epub 2015 May 23.


Confronting the missing epistasis problem: on the reproducibility of gene-gene interactions.

Murk W, Bracken MB, DeWan AT.

Hum Genet. 2015 Aug;134(8):837-49. doi: 10.1007/s00439-015-1564-3. Epub 2015 May 22.


Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.

Patterson VL, Zullo AJ, Koenig C, Stoessel S, Jo H, Liu X, Han J, Choi M, DeWan AT, Thomas JL, Kuan CY, Hoh J.

PLoS One. 2014 Dec 22;9(12):e115789. doi: 10.1371/journal.pone.0115789. eCollection 2014.


Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia.

Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK.

Am J Hypertens. 2015 Jul;28(7):915-23. doi: 10.1093/ajh/hpu242. Epub 2014 Dec 17.


Longitudinal associations between asthma and general and abdominal weight status among Norwegian adolescents and young adults: the HUNT Study.

Egan KB, Ettinger AS, DeWan AT, Holford TR, Holmen TL, Bracken MB.

Pediatr Obes. 2015 Oct;10(5):345-52. doi: 10.1111/ijpo.271. Epub 2014 Nov 18.


General, but not abdominal, overweight increases odds of asthma among Norwegian adolescents: the Young-HUNT study.

Egan KB, Ettinger AS, DeWan AT, Holford TR, Holmen TL, Bracken MB.

Acta Paediatr. 2014 Dec;103(12):1270-6. doi: 10.1111/apa.12775. Epub 2014 Sep 10.


Bioinformatic approach to the genetics of preeclampsia.

Triche EW, Uzun A, DeWan AT, Kurihara I, Liu J, Occhiogrosso R, Shen B, Parker J, Padbury JF.

Obstet Gynecol. 2014 Jun;123(6):1155-61. doi: 10.1097/AOG.0000000000000293.


Leptin signaling and hyperparathyroidism: clinical and genetic associations.

Hoang D, Broer N, Roman SA, Yao X, Abitbol N, Li F, Sosa JA, Sue GR, DeWan AT, Wong ML, Licinio J, Simpson C, Li AY, Pizzoferrato N, Narayan D.

J Am Coll Surg. 2014 Jun;218(6):1239-1250.e4. doi: 10.1016/j.jamcollsurg.2013.11.013. Epub 2013 Nov 27.


Pathway-based genetic analysis of preterm birth.

Uzun A, Dewan AT, Istrail S, Padbury JF.

Genomics. 2013 Mar;101(3):163-70. doi: 10.1016/j.ygeno.2012.12.005. Epub 2013 Jan 6.


Association between the SERPINE1 (PAI-1) 4G/5G insertion/deletion promoter polymorphism (rs1799889) and pre-eclampsia: a systematic review and meta-analysis.

Zhao L, Bracken MB, Dewan AT, Chen S.

Mol Hum Reprod. 2013 Mar;19(3):136-43. doi: 10.1093/molehr/gas056. Epub 2012 Nov 23. Review.


Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach.

Jacobs DI, Walsh KM, Wrensch M, Wiencke J, Jenkins R, Houlston RS, Bondy M, Simon M, Sanson M, Gousias K, Schramm J, Labussière M, Di Stefano AL, Wichmann HE, Müller-Nurasyid M, Schreiber S, Franke A, Moebus S, Eisele L, Dewan AT, Dubrow R.

Front Genet. 2012 Oct 12;3:203. doi: 10.3389/fgene.2012.00203. eCollection 2012.


Stage and gene specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo.

Popova EY, Xu X, DeWan AT, Salzberg AC, Berg A, Hoh J, Zhang SS, Barnstable CJ.

PLoS One. 2012;7(10):e46867. doi: 10.1371/journal.pone.0046867. Epub 2012 Oct 9.


Whole-exome sequencing of a pedigree segregating asthma.

DeWan AT, Egan KB, Hellenbrand K, Sorrentino K, Pizzoferrato N, Walsh KM, Bracken MB.

BMC Med Genet. 2012 Oct 9;13:95. doi: 10.1186/1471-2350-13-95.


Association of maternal AGTR1 polymorphisms and preeclampsia: a systematic review and meta-analysis.

Zhao L, Dewan AT, Bracken MB.

J Matern Fetal Neonatal Med. 2012 Dec;25(12):2676-80. doi: 10.3109/14767058.2012.708370. Epub 2012 Aug 3. Review.


Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients.

Zhao L, Triche EW, Walsh KM, Bracken MB, Saftlas AF, Hoh J, Dewan AT.

BMC Pregnancy Childbirth. 2012 Jun 29;12:61.


Disease risk prediction with rare and common variants.

Wu C, Walsh KM, Dewan AT, Hoh J, Wang Z.

BMC Proc. 2011 Nov 29;5 Suppl 9:S61. doi: 10.1186/1753-6561-5-S9-S61.


Genetic signatures of exceptional longevity in humans.

Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Hoh J, Perls TT.

PLoS One. 2012;7(1):e29848. doi: 10.1371/journal.pone.0029848. Epub 2012 Jan 18.


Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.

Murk W, Walsh K, Hsu LI, Zhao L, Bracken MB, Dewan AT.

Hum Hered. 2011;71(2):97-105. doi: 10.1159/000319536. Epub 2011 Jul 6.


A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.

Walsh KM, Choi M, Oberg K, Kulke MH, Yao JC, Wu C, Jurkiewicz M, Hsu LI, Hooshmand SM, Hassan M, Janson ET, Cunningham JL, Vosburgh E, Sackler RS, Lifton RP, Dewan AT, Hoh J.

Endocr Relat Cancer. 2011 Jan 13;18(1):171-80. doi: 10.1677/ERC-10-0248. Print 2011 Feb.


PDE11A associations with asthma: results of a genome-wide association scan.

DeWan AT, Triche EW, Xu X, Hsu LI, Zhao C, Belanger K, Hellenbrand K, Willis-Owen SA, Moffatt M, Cookson WO, Himes BE, Weiss ST, Gauderman WJ, Baurley JW, Gilliland F, Wilk JB, O'Connor GT, Strachan DP, Hoh J, Bracken MB.

J Allergy Clin Immunol. 2010 Oct;126(4):871-873.e9. doi: 10.1016/j.jaci.2010.06.051. No abstract available.


Five classic articles in genetic epidemiology.

DeWan AT.

Yale J Biol Med. 2010 Jun;83(2):87-90.


Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism.

Walsh KM, Bracken MB, Murk WK, Hoh J, Dewan AT.

Mutat Res. 2010 Aug 7;690(1-2):89-94. doi: 10.1016/j.mrfmmm.2010.05.005. Epub 2010 May 27.

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