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Items: 17

1.

LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.

Poffenberger MC, Metcalfe-Roach A, Aguilar E, Chen J, Hsu BE, Wong AH, Johnson RM, Flynn B, Samborska B, Ma EH, Gravel SP, Tonelli L, Devorkin L, Kim P, Hall A, Izreig S, Loginicheva E, Beauchemin N, Siegel PM, Artyomov MN, Lum JJ, Zogopoulos G, Blagih J, Jones RG.

Science. 2018 Jul 27;361(6400):406-411. doi: 10.1126/science.aan3975.

PMID:
30049881
2.

Raman Spectroscopic Signatures Reveal Distinct Biochemical and Temporal Changes in Irradiated Human Breast Adenocarcinoma Xenografts.

Van Nest SJ, Nicholson LM, DeVorkin L, Brolo AG, Lum JJ, Jirasek A.

Radiat Res. 2018 May;189(5):497-504. doi: 10.1667/RR15003.1. Epub 2018 Feb 23.

PMID:
29474157
3.

Ex Vivo Detection of Circulating Tumor Cells from Whole Blood by Direct Nanoparticle Visualization.

Sobral-Filho RG, DeVorkin L, Macpherson S, Jirasek A, Lum JJ, Brolo AG.

ACS Nano. 2018 Feb 27;12(2):1902-1909. doi: 10.1021/acsnano.7b08813. Epub 2018 Feb 7.

PMID:
29401387
4.

Hsp83 loss suppresses proteasomal activity resulting in an upregulation of caspase-dependent compensatory autophagy.

Choutka C, DeVorkin L, Go NE, Hou YC, Moradian A, Morin GB, Gorski SM.

Autophagy. 2017 Sep 2;13(9):1573-1589. doi: 10.1080/15548627.2017.1339004. Epub 2017 Aug 14.

5.

Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma.

DeVorkin L, Hattersley M, Kim P, Ries J, Spowart J, Anglesio MS, Levi SM, Huntsman DG, Amaravadi RK, Winkler JD, Tinker AV, Lum JJ.

Mol Cancer Res. 2017 Mar;15(3):250-258. doi: 10.1158/1541-7786.MCR-16-0132. Epub 2017 Feb 9.

6.

Raman spectroscopy identifies radiation response in human non-small cell lung cancer xenografts.

Harder SJ, Isabelle M, DeVorkin L, Smazynski J, Beckham W, Brolo AG, Lum JJ, Jirasek A.

Sci Rep. 2016 Feb 17;6:21006. doi: 10.1038/srep21006.

7.

Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines?

Lebovitz CB, DeVorkin L, Bosc D, Rothe K, Singh J, Bally M, Jiang X, Young RN, Lum JJ, Gorski SM.

Autophagy. 2015;11(10):1949-52. doi: 10.1080/15548627.2015.1078962.

8.

The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy.

Chittaranjan S, Xu J, Kuzyk M, Dullat HK, Wilton J, DeVorkin L, Lebovitz C, Morin GB, Marra MA, Gorski SM.

Biol Open. 2015 Apr 2;4(5):672-84. doi: 10.1242/bio.20148417.

9.

Survival of effector CD8+ T cells during influenza infection is dependent on autophagy.

Schlie K, Westerback A, DeVorkin L, Hughson LR, Brandon JM, MacPherson S, Gadawski I, Townsend KN, Poon VI, Elrick MA, Côté HC, Abraham N, Wherry EJ, Mizushima N, Lum JJ.

J Immunol. 2015 May 1;194(9):4277-86. doi: 10.4049/jimmunol.1402571. Epub 2015 Apr 1.

10.

Genetic manipulation of autophagy in the Drosophila ovary.

DeVorkin L, Gorski SM.

Cold Spring Harb Protoc. 2014 Sep 2;2014(9):973-9. doi: 10.1101/pdb.prot080358.

PMID:
25183818
11.

Monitoring autophagy in Drosophila using fluorescent reporters in the UAS-GAL4 system.

DeVorkin L, Gorski SM.

Cold Spring Harb Protoc. 2014 Sep 2;2014(9):967-72. doi: 10.1101/pdb.prot080341.

PMID:
25183817
12.

Monitoring autophagic flux using Ref(2)P, the Drosophila p62 ortholog.

DeVorkin L, Gorski SM.

Cold Spring Harb Protoc. 2014 Sep 2;2014(9):959-66. doi: 10.1101/pdb.prot080333.

PMID:
25183816
13.

LysoTracker staining to aid in monitoring autophagy in Drosophila.

DeVorkin L, Gorski SM.

Cold Spring Harb Protoc. 2014 Sep 2;2014(9):951-8. doi: 10.1101/pdb.prot080325.

PMID:
25183815
14.

A mitochondrial-associated link between an effector caspase and autophagic flux.

DeVorkin L, Gorski SM.

Autophagy. 2014 Oct 1;10(10):1866-7. doi: 10.4161/auto.32170. Epub 2014 Aug 13.

15.

The Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB.

DeVorkin L, Go NE, Hou YC, Moradian A, Morin GB, Gorski SM.

J Cell Biol. 2014 May 26;205(4):477-92. doi: 10.1083/jcb.201303144.

16.

Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and -resistant triple-negative breast cancer.

Chittaranjan S, Bortnik S, Dragowska WH, Xu J, Abeysundara N, Leung A, Go NE, DeVorkin L, Weppler SA, Gelmon K, Yapp DT, Bally MB, Gorski SM.

Clin Cancer Res. 2014 Jun 15;20(12):3159-73. doi: 10.1158/1078-0432.CCR-13-2060. Epub 2014 Apr 10.

17.

Steroid hormone control of cell death and cell survival: molecular insights using RNAi.

Chittaranjan S, McConechy M, Hou YC, Freeman JD, Devorkin L, Gorski SM.

PLoS Genet. 2009 Feb;5(2):e1000379. doi: 10.1371/journal.pgen.1000379. Epub 2009 Feb 13.

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