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Items: 6


Structures of human steroidogenic cytochrome P450 17A1 with substrates.

Petrunak EM, DeVore NM, Porubsky PR, Scott EE.

J Biol Chem. 2014 Nov 21;289(47):32952-64. doi: 10.1074/jbc.M114.610998. Epub 2014 Oct 9.


Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes.

DeVore NM, Scott EE.

J Biol Chem. 2012 Aug 3;287(32):26576-85. doi: 10.1074/jbc.M112.372813. Epub 2012 Jun 14.


Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001.

DeVore NM, Scott EE.

Nature. 2012 Jan 22;482(7383):116-9. doi: 10.1038/nature10743.


Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.

DeVore NM, Meneely KM, Bart AG, Stephens ES, Battaile KP, Scott EE.

FEBS J. 2012 May;279(9):1621-31. doi: 10.1111/j.1742-4658.2011.08412.x. Epub 2011 Nov 25.


Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes.

DeVore NM, Smith BD, Wang JL, Lushington GH, Scott EE.

Drug Metab Dispos. 2009 Jun;37(6):1319-27. doi: 10.1124/dmd.109.026765. Epub 2009 Feb 27.


Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes.

DeVore NM, Smith BD, Urban MJ, Scott EE.

Drug Metab Dispos. 2008 Dec;36(12):2582-90. doi: 10.1124/dmd.108.023770. Epub 2008 Sep 8.

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