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Items: 28


CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer.

Ferrandon S, DeVecchio J, Duraes L, Chouhan H, Karagkounis G, Davenport J, Orloff M, Liska D, Kalady MF.

Cancer Res. 2019 Nov 8. pii: canres.1161.2019. doi: 10.1158/0008-5472.CAN-19-1161. [Epub ahead of print]


Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome.

Hitchins MP, Vogelaar IP, Brennan K, Haraldsdottir S, Zhou N, Martin B, Alvarez R, Yuan X, Kim S, Guindi M, Hendifar AE, Kalady MF, DeVecchio J, Church JM, de la Chapelle A, Hampel H, Pearlman R, Christensen M, Snyder C, Lanspa SJ, Haile RW, Lynch HT.

BMJ Open Gastroenterol. 2019 May 28;6(1):e000299. doi: 10.1136/bmjgast-2019-000299. eCollection 2019.


A Changing Spectrum of Colorectal Cancer Biology With Age: Implications for the Young Patient.

Chouhan H, Ferrandon S, DeVecchio J, Kalady MF, Church JM.

Dis Colon Rectum. 2019 Jan;62(1):21-26. doi: 10.1097/DCR.0000000000001188.


Poly(ADP-Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer-Initiating Cells to Chemotherapy.

Jarrar A, Lotti F, DeVecchio J, Ferrandon S, Gantt G, Mace A, Karagkounis G, Orloff M, Venere M, Hitomi M, Lathia J, Rich JN, Kalady MF.

Stem Cells. 2019 Jan;37(1):42-53. doi: 10.1002/stem.2929. Epub 2018 Nov 12.


Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers.

Liang J, Zhou W, Sakre N, DeVecchio J, Ferrandon S, Ting AH, Bao S, Bissett I, Church J, Kalady MF.

Br J Cancer. 2018 Nov;119(10):1267-1277. doi: 10.1038/s41416-018-0249-9. Epub 2018 Oct 15.


Simvastatin enhances radiation sensitivity of colorectal cancer cells.

Karagkounis G, DeVecchio J, Ferrandon S, Kalady MF.

Surg Endosc. 2018 Mar;32(3):1533-1539. doi: 10.1007/s00464-017-5841-1. Epub 2017 Sep 15.


RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis.

Karunanithi S, Levi L, DeVecchio J, Karagkounis G, Reizes O, Lathia JD, Kalady MF, Noy N.

Stem Cell Reports. 2017 Aug 8;9(2):438-450. doi: 10.1016/j.stemcr.2017.06.002. Epub 2017 Jul 6.


NPTX2 is associated with neoadjuvant therapy response in rectal cancer.

Karagkounis G, Thai L, DeVecchio J, Gantt GA, Duraes L, Pai RK, Kalady MF.

J Surg Res. 2016 May 1;202(1):112-7. doi: 10.1016/j.jss.2015.12.042. Epub 2015 Dec 30.


Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain.

Demelash A, Pfannenstiel LW, Tannenbaum CS, Li X, Kalady MF, DeVecchio J, Gastman BR.

J Biol Chem. 2015 Sep 4;290(36):21962-75. doi: 10.1074/jbc.M115.663898. Epub 2015 Jul 23.


Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.

Yan K, Wu Q, Yan DH, Lee CH, Rahim N, Tritschler I, DeVecchio J, Kalady MF, Hjelmeland AB, Rich JN.

Genes Dev. 2014 May 15;28(10):1085-100. doi: 10.1101/gad.235515.113. Epub 2014 May 1.


Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.

Lotti F, Jarrar AM, Pai RK, Hitomi M, Lathia J, Mace A, Gantt GA Jr, Sukhdeo K, DeVecchio J, Vasanji A, Leahy P, Hjelmeland AB, Kalady MF, Rich JN.

J Exp Med. 2013 Dec 16;210(13):2851-72. doi: 10.1084/jem.20131195. Epub 2013 Dec 9.


Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells.

Mazumdar T, Sandhu R, Qadan M, DeVecchio J, Magloire V, Agyeman A, Li B, Houghton JA.

PLoS One. 2013 Sep 25;8(9):e75253. doi: 10.1371/journal.pone.0075253. eCollection 2013.


The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.

Mazumdar T, DeVecchio J, Agyeman A, Shi T, Houghton JA.

Oncotarget. 2011 Aug;2(8):638-45.


An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737.

Al-Harbi S, Hill BT, Mazumder S, Singh K, Devecchio J, Choudhary G, Rybicki LA, Kalaycio M, Maciejewski JP, Houghton JA, Almasan A.

Blood. 2011 Sep 29;118(13):3579-90. doi: 10.1182/blood-2011-03-340364. Epub 2011 Jul 19.


Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.

Mazumdar T, Devecchio J, Agyeman A, Shi T, Houghton JA.

Cancer Res. 2011 Sep 1;71(17):5904-14. doi: 10.1158/0008-5472.CAN-10-4173. Epub 2011 Jul 11.


Hedgehog signaling drives cellular survival in human colon carcinoma cells.

Mazumdar T, DeVecchio J, Shi T, Jones J, Agyeman A, Houghton JA.

Cancer Res. 2011 Feb 1;71(3):1092-102. doi: 10.1158/0008-5472.CAN-10-2315. Epub 2010 Dec 6.


cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.

Shi T, Mazumdar T, Devecchio J, Duan ZH, Agyeman A, Aziz M, Houghton JA.

PLoS One. 2010 Oct 1;5(10). pii: e13054. doi: 10.1371/journal.pone.0013054.


CpG-induced IFNgamma expands TLR4-specific IL-18 responses in vivo.

Gupta S, Gould MP, DeVecchio J, Canaday DH, Auletta JJ, Heinzel FP.

Cell Immunol. 2006 Oct;243(2):75-82. Epub 2007 Feb 9.


In vivo and in vitro regulation of type I IFN synthesis by synergistic effects of CD40 and type II IFN.

Greene JA, DeVecchio JL, Gould MP, Auletta JJ, Heinzel FP.

J Immunol. 2006 May 15;176(10):5995-6003.


Fms-like tyrosine kinase 3-based immunoprophylaxis against infection is improved by adjuvant treatment with anti-interleukin-10 antibody.

Das L, DeVecchio J, Heinzel FP.

J Infect Dis. 2005 Aug 15;192(4):693-702. Epub 2005 Jul 14.


Interleukin 12 and interferon-gamma synthetic deficiency is associated with dendritic cell cytopenia after cardiac surgery.

Yadavalli GK, Chien JW, Wener KM, Devecchio JL, Gupta S, Salata RA, Lee JH, Caldeira C, Auletta JJ, Heinzel FP.

Shock. 2005 Jul;24(1):26-33.


Distinct phases in recovery of reconstituted innate cellular-mediated immunity after murine syngeneic bone marrow transplantation.

Auletta JJ, Devecchio JL, Ferrara JL, Heinzel FP.

Biol Blood Marrow Transplant. 2004 Dec;10(12):834-47.


Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.

Gould MP, Greene JA, Bhoj V, DeVecchio JL, Heinzel FP.

J Immunol. 2004 Feb 1;172(3):1754-62.


Modulation of T-cell costimulation as immunotherapy or immunochemotherapy in experimental visceral leishmaniasis.

Murray HW, Lu CM, Brooks EB, Fichtl RE, DeVecchio JL, Heinzel FP.

Infect Immun. 2003 Nov;71(11):6453-62.


Immunoenhancement combined with amphotericin B as treatment for experimental visceral leishmaniasis.

Murray HW, Brooks EB, DeVecchio JL, Heinzel FP.

Antimicrob Agents Chemother. 2003 Aug;47(8):2513-7.


Determinants of response to interleukin-10 receptor blockade immunotherapy in experimental visceral leishmaniasis.

Murray HW, Moreira AL, Lu CM, DeVecchio JL, Matsuhashi M, Ma X, Heinzel FP.

J Infect Dis. 2003 Aug 1;188(3):458-64. Epub 2003 Jul 14.


Combining benchmarking with other quality tools to achieve breakthroughs in admitting.

Covey B, DeVecchio JH, Mitchell L.

Jt Comm J Qual Improv. 1994 Oct;20(10):555-61.


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