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Items: 1 to 50 of 93

1.

Synthesis and evaluation of 2-halogenated-1,1-bis(4-hydroxyphenyl)-2-(3-hydroxyphenyl)-ethylenes as potential estrogen receptor-targeted radiodiagnostic and radiotherapeutic agents.

Hanson RN, Tongcharoensirikul P, Barnsley K, Ondrechen MJ, Hughes A, DeSombre ER.

Steroids. 2015 Apr;96:50-62. doi: 10.1016/j.steroids.2015.01.013. Epub 2015 Jan 29.

PMID:
25637676
2.

Structural plasticity in the oestrogen receptor ligand-binding domain.

Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL.

EMBO Rep. 2007 Jun;8(6):563-8. Epub 2007 Apr 27. Erratum in: EMBO Rep. 2007 Jun;8(6):610. Guo, Yuee [added]; Hughs, Alun [removed].

4.

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL.

J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28.

6.
7.

Evaluation of 17alpha-E-(trifluoromethylphenyl)vinyl estradiols as novel estrogen receptor ligands.

Hanson RN, Lee CY, Friel C, Hughes A, DeSombre ER.

Steroids. 2003 Feb;68(2):143-8.

PMID:
12606005
9.

Production of clustered DNA damage by 125I decay.

Yasui LS, Hughes A, DeSombre ER.

Acta Oncol. 2000;39(6):739-40. No abstract available.

PMID:
11130013
11.
12.
13.

DNA and chromosome breaks induced by iodine-123-labeled estrogen in Chinese hamster ovary cells.

Schwartz JL, Mustafi R, Hughes A, DeSombre ER.

Radiat Res. 1996 Aug;146(2):151-8.

PMID:
8693065
14.

DNA damage induction by 125I-estrogen.

Yasui LS, Hughes A, DeSombre ER.

Acta Oncol. 1996;35(7):841-7.

PMID:
9004761
15.

Cellular and subcellular studies of the radiation effects of Auger electron-emitting estrogens.

DeSombre ER, Hughes A, Landel CC, Greene G, Hanson R, Schwartz JL.

Acta Oncol. 1996;35(7):833-40.

PMID:
9004760
16.
18.

A revised method for the synthesis of 1,1-bis(4-hydroxyphenyl)-2-phenylethylene (BHPE) and its derivatives.

Shafii B, Atcher RW, Desombre ER.

Nucl Med Biol. 1993 Apr;20(3):371-4. No abstract available.

PMID:
8485499
20.

Estrogen receptor-directed radiotoxicity with Auger electrons: specificity and mean lethal dose.

DeSombre ER, Shafii B, Hanson RN, Kuivanen PC, Hughes A.

Cancer Res. 1992 Oct 15;52(20):5752-8.

21.

Production of no carrier added 80mBr for investigation of Auger electron toxicity.

Mease RC, DeJesus OT, Gatley SJ, Harper PV, Desombre ER, Friedman AM.

Int J Rad Appl Instrum A. 1991;42(1):57-61.

PMID:
1850394
22.
23.
24.

Receptor-directed radiotherapy: a new approach to therapy of steroid receptor positive cancers.

DeSombre ER, Hughes A, Gatley SJ, Schwartz JL, Harper PV.

Prog Clin Biol Res. 1990;322:295-309. Review. No abstract available.

PMID:
2406735
25.

Estrogens, receptors and cancer: the scientific contributions of Elwood Jensen.

DeSombre ER.

Prog Clin Biol Res. 1990;322:17-29. No abstract available.

PMID:
2406730
26.

Significance of apocrine metaplasia in mammary carcinogenesis. A preliminary morphological and immunohistochemical study.

Tóth J, Számel I, Svastics E, DeSombre ER.

Ann N Y Acad Sci. 1990;586:238-51. No abstract available.

PMID:
2357004
27.
28.

The estrogen-responsive 110K and 74K rat uterine secretory proteins are structurally related to complement component C3.

Kuivanen PC, Capulong RB, Harkins RN, DeSombre ER.

Biochem Biophys Res Commun. 1989 Feb 15;158(3):898-905.

PMID:
2645873
29.

Bromine-80m radiotoxicity and the potential for estrogen receptor-directed therapy with auger electrons.

DeSombre ER, Harper PV, Hughes A, Mease RC, Gatley SJ, DeJesus OT, Schwartz JL.

Cancer Res. 1988 Oct 15;48(20):5805-9.

30.

Estrogen receptor binding affinity and uterotrophic activity of triphenylhaloethylenes.

DeSombre ER, Mease RC, Sanghavi J, Singh T, Seevers RH, Hughes A.

J Steroid Biochem. 1988 Jun;29(6):583-90.

PMID:
3386226
31.
32.
33.

Immunochemical studies of estrogen receptors.

Jensen EV, Greene GL, DeSombre ER.

Prog Clin Biol Res. 1987;249:283-305. Review.

PMID:
3313429
34.

Prognostic usefulness of estrogen receptor immunocytochemical assays for human breast cancer.

DeSombre ER, Thorpe SM, Rose C, Blough RR, Andersen KW, Rasmussen BB, King WJ.

Cancer Res. 1986 Aug;46(8 Suppl):4256s-4264s.

35.

The synthesis of non-steroidal estrogen receptor binding compounds labeled with 80mBr.

Seevers RH, Mease RC, Friedman AM, Desombre ER.

Int J Rad Appl Instrum B. 1986;13(4):483-95.

PMID:
3793506
36.

Steroid hormone receptors as prognostic indicators in primary breast cancer.

Thorpe SM, Rose C, Rasmussen BB, King WJ, DeSombre ER, Blough RM, Mouridsen HT, Rossing N, Andersen KW.

Breast Cancer Res Treat. 1986;7 Suppl:S91-7.

PMID:
3527307
38.

Progestin modulation of estrogen-dependent marker protein synthesis in the endometrium.

DeSombre ER, Kuivanen PC.

Semin Oncol. 1985 Mar;12(1 Suppl 1):6-11.

PMID:
3975654
39.

Comparison of immunocytochemical and steroid-binding assays for estrogen receptor in human breast tumors.

King WJ, DeSombre ER, Jensen EV, Greene GL.

Cancer Res. 1985 Jan;45(1):293-304.

41.

Estrogen receptors, antibodies and hormone dependent cancer.

DeSombre ER, Greene GL, King WJ, Jensen EV.

Prog Clin Biol Res. 1984;142:1-21. No abstract available.

PMID:
6538684
42.

Steroid receptors in breast cancer.

Desombre ER.

Monogr Pathol. 1984;(25):149-74.

PMID:
6377047
43.

Epithelial peroxidase and endometrial granulocytes in the normal cyclic human endometrium.

Press MF, DeSombre ER, Talerman A.

J Clin Endocrinol Metab. 1983 Aug;57(2):254-61.

PMID:
6863474
44.

Interaction of [3H] estradiol - and [3H] monohydroxytamoxifen-estrogen receptor complexes with a monoclonal antibody.

Tate AC, DeSombre ER, Greene GL, Jensen EV, Jordan VC.

Breast Cancer Res Treat. 1983;3(3):267-77.

PMID:
6671136
45.

Calculating specific binding for prolactin receptor assays.

Brooks CL, Leinen JG, DeSombre ER, Jensen EV.

Mol Cell Endocrinol. 1982 Apr;26(1-2):81-94.

PMID:
6282673
46.

Characterization of [125I]-iodo-ovine prolactin and evaluation of prolactin receptor assay methods.

Brooks CL, DeSombre ER, Jensen EV.

Horm Res. 1982;16(6):365-76.

PMID:
6295905
47.

Receptors reconsidered: a 20-year perspective.

Jensen EV, Greene GL, Closs LE, DeSombre ER, Nadji M.

Recent Prog Horm Res. 1982;38:1-40. Review. No abstract available.

PMID:
6289391
48.

Localization of uterine peroxidase activity in estrogen-treated rats.

King WJ, Allen TC, DeSombre ER.

Biol Reprod. 1981 Nov;25(4):859-70. No abstract available.

PMID:
6272895
49.
50.

Special report. Steriod receptors in breast cancer.

DeSombre ER, Carbone PP, Jensen EV, McGuire WL, Wells SA Jr, Wittliff JL, Lipsett MB.

N Engl J Med. 1979 Nov 1;301(18):1011-2. No abstract available.

PMID:
492228

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